Sex Chromosomal Homologies between Human and Fish Karyotypes Revealed by Chromosome Painting

Yi Meisheng1, Yu Qixing1
1Department of Genetics, College of Life Sciences, Wuhan University, Wuhan, China

Tóm tắt

Human sex chromosome-specific probes were hybridized to metaphase spreads of three fish species, Monopterus albus Zuiew, Danio rerioandMastacembelus aculeatusBasilewsky, to reveal evolutionary conservation of sex chromosomal segments between distantly related species of vertebrates. The human X chromosomal paint disclosed 4, 8, and 6 conserved syntenic segments in the karyotypes of the three fish species respectively, which were scattered in several pairs of homologous chromosomes. But no conserved segment was identified in our experiments when the human Y chromosomal probes were used. The evolution of the X chromosome of vertebrates is discussed.

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