Severe cyclical thrombocytopenia in a patient with a large lymphatic–venous malformation: A potential association?

Australasian Journal of Dermatology - Tập 42 Số 1 - Trang 38-42 - 2001
Li‐Chuen Wong1, Maureen Rogers2, A Lammi2
1Departments of Dermatology and
2Haematology, Royal Alexandra Hospital for Children, Sydney, New South Wales, Australia

Tóm tắt

SUMMARYThe case is reported of an infant who had a large vascular malformation involving his left arm and axillar. It was initially believed to be purely lymphatic in composition but some venous elements were identified subsequently, at operation. The lesion was unusual in that there was a total absence of skin over one area of it at birth, that it underwent spontaneous shrinkage in the early weeks of life, and that a circumferential scarring developed which led to severe functional disability of the limb. At 12 months of age the patient developed a profound cyclic thrombocytopenia that spontaneously resolved after 1 year. The cause of the platelet cycling is unresolved but might have been secondary to intermittent production by the malformation of a cytokine which was destructive against the platelets.

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Australasian Journal of Dermatology

Tập 42 Số 1

38-42

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