Sero-epidemiology of Hepatitis B Among New Refugees to Minnesota
Tóm tắt
Hepatitis B virus (HBV) infection is endemic in many parts of the world, and prevailing conditions in refugee situations result in greater risk of infection. The objectives of this study were to determine the period prevalence of HBV infection among primary refugees in Minnesota during 1998–2001; describe trends in prevalence over time and identify patterns of infection and immunity in various refugee populations. A retrospective analysis of health examination data from the Minnesota Department of Health was conducted to examine serologic markers for hepatitis B: HBcAb, HbsAg, and HBsAb among 12,505 refugees who participated in the voluntary domestic health examination from 1998 to 2001. One hundred and eleven refugees had at least one immunization before arrival and were excluded. There was documented HBV test results in 8,754 (70.6%) of refugees; period prevalence of hepatitis B infection was 7.1%. Africans were three times more likely and Asians 2.4 times more likely to be infected than Europeans (P < 0.001). Older African refugees and African males were more likely to be infected than younger African refugees and women African refugees (P < 0.001). Younger persons below 30 years of age accounted for over 70% of all infected refugees in this study. Reducing the burden of infection among refugees requires enhanced provider awareness as well as intensified efforts aimed at identifying new at-risk populations, modifying risk factors, and implementing preventive and treatment strategies at various levels in the refugee resettlement process.
Tài liệu tham khảo
World health organization. Hepatitis B fact sheet. Available at http://www.who.int/mediacentre/factsheets/fs204/en/index.html. Accessed 31 July 2007.
Poland GA, Jacobson RM. Prevention of hepatitis B with the hepatitis B vaccine. N Engl J Med 2004;351:2832–38.
Gogos CA, Fouka KP, Nikiforidis G, et al. Prevalence of hepatitis B and C virus infection in the general population and selected groups in south-western Greece. Eur J Epidemiol 2003;18:551–57.
World Health Organization vaccine-preventable diseases: monitoring systems, 2004 global summary: Available at http://www.who.int/vaccines-documents/GlobalSummary/GlobalSummary.pdf. Accessed 31 July 2007.
Lansang MA. Epidemiology and control of hepatitis B infection: a perspective from the Phillipines, Asia. Gut 1996;38(suppl 2):S43–7.
Kiire CF. The epidemiology and prophylaxis of hepatitis B in sub-Saharan Africa: a view from tropical and subtropical Africa. Gut 1996;38(Suppl 2):S5–12.
Santantonio T, Lo Caputo S, Germinario C, et al. Prevalence of hepatitis virus infections in Albanian refugees. Eur J Epidemiol 1993;9(5):537–40.
Karim SS, Thejpal R, Singh B. High prevalence of hepatitis B virus infection in rural black adults in Mseleni, South Africa. Am J Public Health 1989;79(7):893–4.
Chironna M, Germinario C, Lopalco PL, Carrozzini F, Barbuti S, Quarto M. Prevalence rates of viral hepatitis infections in refugee Kurds from Iraq and Turkey. Infection 2003;31(2):70–4.
Hurie MB, Mast EE, Davis JP. Horizontal transmission of hepatitis B virus infection to United States-born children of Hmong refugees. Pediatrics 1992;89(2):269–73.
Whittle HC, Bradley HK, McLauchan K, et al. Hepatitis B virus infection in two Gambian villages. Lancet 1983;1(8335):1203–6.
Prozesky OW, Szmuness W, Stevens CE, et al. Baseline epidemiological studies for a hepatitis B vaccine trial in Kangwane. S Afr Med J 1983;64(23):891–93.
Botha JF, Ritchie MJ, Dusheiko GM, Mouton HW, Kew MC. Hepatitis B virus carrier state in black children in Ovamboland: role of perinatal and horizontal infection. Lancet 1984;1(8388):1210–2.
Barin F, Perrin J, Chotard J, et al. Cross-sectional and longitudinal epidemiology of hepatitis B in Senegal. Prog Med Virol 1981;27:148–62.
Kane A, Lloyd J, Zaffran M, Simonsen L, Kane M. Transmission of hepatitis B, hepatitis C and human immunodeficiency viruses through unsafe injections in the developing world: model-based regional estimates. Bull World Health Organ 1999;77(10):801–7.
Kew MC, Reis P, Macnab GM, Seftel HC, Bersohn I. The witch-doctor and tribal scarifications of the skin and the hepatitis B antigen. S Afr Med J 1973;47(50):2419–20.
Johnson CJ, Anderson H, Spearman J, Madon J. Ear-piercing and hepatitis: nonsterile instruments for ear piercing and the subsequent onset of viral hepatitis. JAMA 1974;227(10):1165.
West DJ, Margolis HS. Prevention of hepatitis B virus infection in the United States: a pediatric perspective. Pediat Infect Dis J 1992;11(10):866–74.
Margolis HS. Prevention of acute and chronic liver disease through immunization: hepatitis B and beyond. J Inf Dis 1993;168(1):9–14.
Bhimma R, Coovadia HM, Adhikari M, Connolly CA. The impact of the hepatitis B virus vaccine on the incidence of hepatitis B virus-associated membranous nephropathy. Arch Pediatr Adolesc Med 2003;157(10):1025–30.