Serial 4DCT/4DPET imaging to predict and monitor response for locally-advanced non-small cell lung cancer chemo-radiotherapy

Aupérin, 2010, Meta-analysis of concomitant versus sequential radiochemotherapy in locally advanced non-small-cell lung cancer, J Clin Oncol, 28, 2181, 10.1200/JCO.2009.26.2543 Bradley, 2013, A randomized phase III comparison of standard-dose (60 Gy) versus high-dose (74 Gy) conformal chemoradiotherapy with or without cetuximab for stage III non-small cell lung cancer: Results on radiation dose in RTOG 0617, J Clin Oncol, 31, 1, 10.1200/jco.2013.31.15_suppl.7501 van Baardwijk, 2008, Individualized radical radiotherapy of non-small-cell lung cancer based on normal tissue dose constraints: a feasibility study, Int J Radiat Oncol Biol Phys, 71, 1394, 10.1016/j.ijrobp.2007.11.070 Feng, 2009, Using fluorodeoxyglucose positron emission tomography to assess tumor volume during radiotherapy for non-small-cell lung cancer and its potential impact on adaptive dose escalation and normal tissue sparing, Int J Radiat Oncol Biol Phys, 73, 1228, 10.1016/j.ijrobp.2008.10.054 Gensheimer, 2017, Mid-radiotherapy PET/CT for prognostication and detection of early progression in patients with stage III non-small cell lung cancer, Radiother Oncol, 10.1016/j.radonc.2017.08.007 Ashley Cox, 2017, Survival and central photopenia detected by fluorine-18 fluoro-deoxy-glucose positron emission tomography (FDG-PET) in patients with locoregional non-small cell lung cancer treated with radiotherapy, Radiother Oncol, 124, 25, 10.1016/j.radonc.2017.06.004 Carvalho, 2016, Early variation of FDG-PET radiomics features in NSCLC is related to overall survival – the “delta radiomics” concept, Radiother Oncol, 118, S20, 10.1016/S0167-8140(16)30042-1 Konert, 2016, Multiple training interventions significantly improve reproducibility of PET/CT-based lung cancer radiotherapy target volume delineation using an IAEA study protocol, Radiother Oncol, 121, 39, 10.1016/j.radonc.2016.09.002 Nygård, 2016, Early lesion-specific 18F-FDG PET response to chemotherapy predicts time to lesion progression in locally advanced non-small cell lung cancer, Radiother Oncol, 118, 460, 10.1016/j.radonc.2016.01.009 Yue, 2017, Association of lung fluorodeoxyglucose uptake with radiation pneumonitis after concurrent chemoradiation for non-small cell lung cancer, Clin Transl Radiat Oncol, 4, 1, 10.1016/j.ctro.2017.04.001 De Ruysscher, 2010, PET scans in radiotherapy planning of lung cancer, Radiother Oncol, 96, 335, 10.1016/j.radonc.2010.07.002 Van Diessen, 2017, PO-0888: response monitoring by 18FDG-PET in locally advanced NSCLC treated with concurrent chemoradiotherapy, Radiother Oncol, 123, S488, 10.1016/S0167-8140(17)31325-7 Lim, 2011, Tumor regression and positional changes in non-small cell lung cancer during radical radiotherapy, J Thorac Oncol, 6, 531, 10.1097/JTO.0b013e31820b8a52 Bertelsen, 2011, Radiation dose response of normal lung assessed by Cone Beam CT – a potential tool for biologically adaptive radiation therapy, Radiother Oncol, 100, 351, 10.1016/j.radonc.2011.08.012 Bissonnette, 2009, Cone-Beam Computed Tomographic Image Guidance for Lung Cancer Radiation Therapy, Int J Radiat Oncol Biol Phys, 73, 927, 10.1016/j.ijrobp.2008.08.059 Soike, 2013, Image guided radiation therapy results in improved local control in lung cancer patients treated with fractionated radiation therapy for stage IIB–IIIB disease, Int J Radiat Oncol Biol Phys, 87, S547, 10.1016/j.ijrobp.2013.06.1449 Kupelian, 2005, Serial megavoltage CT imaging during external beam radiotherapy for non-small-cell lung cancer: observations on tumor regression during treatment, Int J Radiat Oncol Biol Phys, 63, 1024, 10.1016/j.ijrobp.2005.04.046 Erridge, 2003, Portal imaging to assess set-up errors, tumor motion and tumor shrinkage during conformal radiotherapy of non-small cell lung cancer, Radiother Oncol, 66, 75, 10.1016/S0167-8140(02)00287-6 Woodford, 2007, Adaptive radiotherapy planning on decreasing gross tumor volumes as seen on megavoltage computed tomography images, Int J Radiat Oncol Biol Phys, 69, 1316, 10.1016/j.ijrobp.2007.07.2369 Britton, 2007, Assessment of gross tumor volume regression and motion changes during radiotherapy for non-small-cell lung cancer as measured by four-dimensional computed tomography, Int J Radiat Oncol Biol Phys, 68, 1036, 10.1016/j.ijrobp.2007.01.021 Britton, 2009, Consequences of anatomic changes and respiratory motion on radiation dose distributions in conformal radiotherapy for locally advanced non-small-cell lung cancer, Int J Radiat Oncol Biol Phys, 73, 94, 10.1016/j.ijrobp.2008.04.016 Erdi, 2000, Use of PET to monitor the response of lung cancer to radiation treatment, Eur J Nucl Med, 27, 861, 10.1007/s002590000258 Ling, 2000, Towards multidimensional radiotherapy (MD-CRT): biological imaging and biological conformality, Int J Radiat Oncol Biol Phys, 47, 551, 10.1016/S0360-3016(00)00467-3 Ung, 2011, Positron emission tomography with 18fluorodeoxyglucose in radiation treatment planning for non-small cell lung cancer: a systematic review, J Thorac Oncol, 6, 86, 10.1097/JTO.0b013e3181fc7687 Hicks, 2009, Role of 18F-FDG PET in assessment of response in non-small cell lung cancer, J Nucl Med, 50, 31S, 10.2967/jnumed.108.057216 Kong, 2007, A pilot study of [18F]fluorodeoxyglucose positron emission tomography scans during and after radiation-based therapy in patients with non small-cell lung cancer, J Clin Oncol, 25, 3116, 10.1200/JCO.2006.10.3747 van Baardwijk, 2007, Time trends in the maximal uptake of FDG on PET scan during thoracic radiotherapy: a prospective study in locally advanced non-small cell lung cancer (NSCLC) patients, Radiother Oncol, 82, 145, 10.1016/j.radonc.2007.01.007 Borst, 2005, Standardised FDG uptake: a prognostic factor for inoperable non-small cell lung cancer, Eur J Cancer, 41, 1533, 10.1016/j.ejca.2005.03.026 Mac Manus, 2005, Metabolic (FDG-PET) response after radical radiotherapy/chemoradiotherapy for non-small cell lung cancer correlates with patterns of failure, Lung Cancer, 49, 95, 10.1016/j.lungcan.2004.11.024 Hoekstra, 2005, Prognostic relevance of response evaluation using [18F]-2-fluoro-2-deoxy-d-glucose positron emission tomography in patients with locally advanced non-small-cell lung cancer, J Clin Oncol, 23, 8362, 10.1200/JCO.2005.01.1189 De Los, 2013, Image guided radiation therapy (IGRT) technologies for radiation therapy localization and delivery, Int J Radiat Oncol Biol Phys, 87, 33, 10.1016/j.ijrobp.2013.02.021 Ohri, 2017, 18F-fluorodeoxyglucose/positron emission tomography predicts patterns of failure after definitive chemoradiation therapy for locally advanced non-small cell lung cancer, Int J Radiat Oncol Biol Phys, 97, 372, 10.1016/j.ijrobp.2016.10.031 Aerts, 2012, Identification of residual metabolic-active areas within NSCLC tumours using a pre-radiotherapy FDG-PET-CT scan: a prospective validation, Lung Cancer, 75, 73, 10.1016/j.lungcan.2011.06.003 Aerts, 2009, Identification of residual metabolic-active areas within individual NSCLC tumours using a pre-radiotherapy (18)Fluorodeoxyglucose-PET-CT scan, Radiother Oncol, 91, 386, 10.1016/j.radonc.2009.03.006 Vera, 2011, Radiother Oncol, 98, 109, 10.1016/j.radonc.2010.10.011 Schwarz, 2005, Early prediction of response to chemotherapy in metastatic breast cancer using sequential 18F-FDG PET, J Nucl Med, 46, 1144 Gallamini, 2006, The predictive value of positron emission tomography scanning performed after two courses of standard therapy on treatment outcome in advanced stage Hodgkin’s disease, Haematologica, 91, 475 Higgins, 2011, Effect of image-guidance frequency on geometric accuracy and setup margins in radiotherapy for locally advanced lung cancer, Int J Radiat Oncol Biol Phys, 80, 1330, 10.1016/j.ijrobp.2010.04.006 Li, 2015, The value of nodal information in predicting lung cancer relapse using 4DPET/4DCT, Med Phys, 42, 4727, 10.1118/1.4926755 Mehmood, 2015, Predicting radiation esophagitis using 18F-FDG PET during chemo-radiotherapy for locally advanced non-small cell lung cancer, J Thorac Oncol, 11, 213, 10.1016/j.jtho.2015.10.006 Nehmeh, 2003, Reduction of respiratory motion artifacts in PET imaging of lung cancer by respiratory correlated dynamic PET: methodology and comparison with respiratory gated PET, J Nucl Med, 44, 1644 Wu, 2013, PET imaging of inflammation biomarkers, Theranostics, 3, 448, 10.7150/thno.6592 Siedschlag, 2011, The impact of microscopic disease on the tumor control probability in non-small-cell lung cancer, Radiother Oncol, 100, 344, 10.1016/j.radonc.2011.08.046 Aristophanous, 2011, Four-dimensional positron emission tomography: implications for dose painting of high-uptake regions, Int J Radiat Oncol Biol Phys, 80, 900, 10.1016/j.ijrobp.2010.08.028 Vines, 2007, Quantitative PET comparing gated with nongated acquisitions using a NEMA phantom with respiratory-simulated motion, J Nucl Med Technol, 35, 246, 10.2967/jnmt.107.040782 Vera, 2007, Does chemotherapy influence the quantification of SUV when contrast-enhanced CT is used in PET/CT in lymphoma?, Eur J Nucl Med Mol Imaging, 34, 1943, 10.1007/s00259-007-0504-4 Hicks, 2004, Early FDG-PET imaging after radical radiotherapy for non-small-cell lung cancer: inflammatory changes in normal tissues correlate with tumor response and do not confound therapeutic response evaluation, Int J Radiat Oncol Biol Phys, 60, 412, 10.1016/j.ijrobp.2004.03.036 Yu, 2009, Comparison of tumor volumes as determined by pathologic examination and FDG-PET/CT images of non-small-cell lung cancer: a pilot study, Int J Radiat Oncol Biol Phys, 75, 1468, 10.1016/j.ijrobp.2009.01.019 Hong, 2008, Impact of manual and automated interpretation of fused PET/CT data on esophageal target definitions in radiation planning, Int J Radiat Oncol Biol Phys, 72, 1612, 10.1016/j.ijrobp.2008.07.061 Biehl, 2006, 18F-FDG PET definition of gross tumor volume for radiotherapy of non-small cell lung cancer: is a single standardized uptake value threshold approach appropriate?, J Nucl Med, 47, 1808 Kleinbaum, 2012 Breiman, 1993 Yap, 2016, Adaptive dose escalation using serial Four-dimensional Positron Emission Tomography/Computed Tomography scans during radiotherapy for locally advanced non-small cell lung cancer, Clin Oncol (R Coll Radiol), 28, e199, 10.1016/j.clon.2016.08.011 van Elmpt, 2012, The PET-boost randomised phase II dose-escalation trial in non-small cell lung cancer, Radiother Oncol, 104, 67, 10.1016/j.radonc.2012.03.005 Bradley, 2015, Lancet Oncol, 16, 187, 10.1016/S1470-2045(14)71207-0 Cox, 2012, Are the results of RTOG 0617 mysterious?, Int J Radiat Oncol Biol Phys, 82, 1042, 10.1016/j.ijrobp.2011.12.032 Usmanij, 2013, 18F-FDG PET early response evaluation of locally advanced non-small cell lung cancer treated with concomitant chemoradiotherapy, J Nucl Med, 54, 1528, 10.2967/jnumed.112.116921 Lambin, 2009, The ESTRO Breur Lecture 2009. From population to voxel-based radiotherapy: exploiting intra-tumour and intra-organ heterogeneity for advanced treatment of non-small cell lung cancer, Radiother Oncol, 96, 145, 10.1016/j.radonc.2010.07.001