Semi‐automated primary tumor volume measurements by dynamic contrast‐enhanced MRI in patients with head and neck cancer
Tóm tắt
Tumor volume is a significant prognostic factor in the treatment of malignant head and neck tumors. Unfortunately, it is not routinely measured because of the workload involved.
Twenty‐one patients, between 2009 and 2010, were studied. Dynamic contrast‐enhanced MRI (DCE‐MRI) at 3.0T was performed. A workstation previously developed for semi‐automated segmentation of breast cancers on DCE‐MRI was used to segment the head and neck cancers. The Pearson correlation analysis was used to assess the agreement between volumetric measurements and the manually derived gross tumor volume (GTV).
In 90.5% of the patients (19 of 21) correlation could be made between DCE‐MRI and the manually derived GTV. The Pearson correlation coefficient between the automatically derived tumor volume at DCE‐MRI and the manually derived GTVs was R2 = 0.95 (
Semi‐automated tumor volumes on DCE‐MRI were representative of those derived from the manually derived GTV (R2 = 0.95;
Từ khóa
Tài liệu tham khảo
Edge SB, 2010, American Joint Committee of Cancer – AJCC Cancer Staging Manual
Fischbein NJ, 2003, Assessment of metastatic cervical adenopathy using dynamic contrast‐enhanced MR imaging, AJNR Am J Neuroradiol, 24, 301