Self-Organization of Polarized Cerebellar Tissue in 3D Culture of Human Pluripotent Stem Cells

Cell Reports - Tập 10 Số 4 - Trang 537-550 - 2015
Keiko Muguruma1, Ayaka Nishiyama1, Hideshi Kawakami2, Kouichi Hashimoto3, Yoshiki Sasai1
1Laboratory for Organogenesis and Neurogenesis, RIKEN Center for Developmental Biology, Kobe 650-0047, Japan
2Department of Epidemiology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, 734-8551, Japan
3Department of Neurophysiology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8551, Japan

Tóm tắt

Từ khóa


Tài liệu tham khảo

Alder, 1999, Generation of cerebellar granule neurons in vivo by transplantation of BMP-treated neural progenitor cells, Nat. Neurosci., 2, 535, 10.1038/9189

Aldinger, 2009, FOXC1 is required for normal cerebellar development and is a major contributor to chromosome 6p25.3 Dandy-Walker malformation, Nat. Genet., 41, 1037, 10.1038/ng.422

Altman, 1985, Embryonic development of the rat cerebellum. II. Translocation and regional distribution of the deep neurons, J. Comp. Neurol., 231, 27, 10.1002/cne.902310104

Ang, 2006, Transcriptional control of midbrain dopaminergic neuron development, Development, 133, 3499, 10.1242/dev.02501

Ben-Arie, 1997, Math1 is essential for genesis of cerebellar granule neurons, Nature, 390, 169, 10.1038/36579

Bulfone, 2000, Barhl1, a gene belonging to a new subfamily of mammalian homeobox genes, is expressed in migrating neurons of the CNS, Hum. Mol. Genet., 9, 1443, 10.1093/hmg/9.9.1443

Chi, 2003, The isthmic organizer signal FGF8 is required for cell survival in the prospective midbrain and cerebellum, Development, 130, 2633, 10.1242/dev.00487

Chizhikov, 2006, The roof plate regulates cerebellar cell-type specification and proliferation, Development, 133, 2793, 10.1242/dev.02441

Davis, 1988, Expression of the homeo box-containing gene En-2 delineates a specific region of the developing mouse brain, Genes Dev., 2, 361, 10.1101/gad.2.3.361

Erceg, 2010, Efficient differentiation of human embryonic stem cells into functional cerebellar-like cells, Stem Cells Dev., 19, 1745, 10.1089/scd.2009.0498

Fink, 2006, Development of the deep cerebellar nuclei: transcription factors and cell migration from the rhombic lip, J. Neurosci., 26, 3066, 10.1523/JNEUROSCI.5203-05.2006

Fischer, 2011, Fgf15-mediated control of neurogenic and proneural gene expression regulates dorsal midbrain neurogenesis, Dev. Biol., 350, 496, 10.1016/j.ydbio.2010.12.017

Gimeno, 2007, Expression of chick Fgf19 and mouse Fgf15 orthologs is regulated in the developing brain by Fgf8 and Shh, Dev. Dyn., 236, 2285, 10.1002/dvdy.21237

Gruol, 1987, Morphological and physiological differentiation of Purkinje neurons in cultures of rat cerebellum, J. Neurosci., 7, 1271, 10.1523/JNEUROSCI.07-05-01271.1987

Hirano, 1986, Voltage-gated and synaptic currents in rat Purkinje cells in dissociated cell cultures, Proc. Natl. Acad. Sci. USA, 83, 1945, 10.1073/pnas.83.6.1945

Hirano, 1988, Synaptic transmission between rat cerebellar granule and Purkinje cells in dissociated cell culture: effects of excitatory-amino acid transmitter antagonists, Proc. Natl. Acad. Sci. USA, 85, 934, 10.1073/pnas.85.3.934

Hoshino, 2005, Ptf1a, a bHLH transcriptional gene, defines GABAergic neuronal fates in cerebellum, Neuron, 47, 201, 10.1016/j.neuron.2005.06.007

Joyner, 2000, Otx2, Gbx2 and Fgf8 interact to position and maintain a mid-hindbrain organizer, Curr. Opin. Cell Biol., 12, 736, 10.1016/S0955-0674(00)00161-7

Lapham, 1971, Human fetal cerebellar cortex: organization and maturation of cells in vitro, Science, 173, 829, 10.1126/science.173.3999.829

Machold, 2005, Math1 is expressed in temporally discrete pools of cerebellar rhombic-lip neural progenitors, Neuron, 48, 17, 10.1016/j.neuron.2005.08.028

Matsuda, 2010, Cbln1 is a ligand for an orphan glutamate receptor δ2, a bidirectional synapse organizer, Science, 328, 363, 10.1126/science.1185152

McMahon, 1992, The midbrain-hindbrain phenotype of Wnt-1-/Wnt-1- mice results from stepwise deletion of engrailed-expressing cells by 9.5 days postcoitum, Cell, 69, 581, 10.1016/0092-8674(92)90222-X

Minaki, 2008, Identification of a novel transcriptional corepressor, Corl2, as a cerebellar Purkinje cell-selective marker, Gene Expr. Patterns, 8, 418, 10.1016/j.gep.2008.04.004

Mizuhara, 2010, Purkinje cells originate from cerebellar ventricular zone progenitors positive for Neph3 and E-cadherin, Dev. Biol., 338, 202, 10.1016/j.ydbio.2009.11.032

Morales, 2006, Molecular markers of neuronal progenitors in the embryonic cerebellar anlage, J. Neurosci., 26, 12226, 10.1523/JNEUROSCI.3493-06.2006

Muguruma, 2010, Ontogeny-recapitulating generation and tissue integration of ES cell-derived Purkinje cells, Nat. Neurosci., 13, 1171, 10.1038/nn.2638

Nakano, 2012, Self-formation of optic cups and storable stratified neural retina from human ESCs, Cell Stem Cell, 10, 771, 10.1016/j.stem.2012.05.009

O’Rahilly, 2006

Raman, 1999, Ionic currents underlying spontaneous action potentials in isolated cerebellar Purkinje neurons, J. Neurosci., 19, 1663, 10.1523/JNEUROSCI.19-05-01663.1999

Salero, 2007, Differentiation of ES cells into cerebellar neurons, Proc. Natl. Acad. Sci. USA, 104, 2997, 10.1073/pnas.0610879104

Seto, 2014, Temporal identity transition from Purkinje cell progenitors to GABAergic interneuron progenitors in the cerebellum, Nat. Commun., 5, 3337, 10.1038/ncomms4337

Su, 2006, Generation of cerebellar neuron precursors from embryonic stem cells, Dev. Biol., 290, 287, 10.1016/j.ydbio.2005.11.010

Tabata, 2000, A reliable method for culture of dissociated mouse cerebellar cells enriched for Purkinje neurons, J. Neurosci. Methods, 104, 45, 10.1016/S0165-0270(00)00323-X

Takebayashi, 2002, Non-overlapping expression of Olig3 and Olig2 in the embryonic neural tube, Mech. Dev., 113, 169, 10.1016/S0925-4773(02)00021-7

Tao, 2010, Efficient generation of mature cerebellar Purkinje cells from mouse embryonic stem cells, J. Neurosci. Res., 88, 234, 10.1002/jnr.22208

Thomas, 1990, Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development, Nature, 346, 847, 10.1038/346847a0

Uemura, 2010, Trans-synaptic interaction of GluRdelta2 and Neurexin through Cbln1 mediates synapse formation in the cerebellum, Cell, 141, 1068, 10.1016/j.cell.2010.04.035

Vernay, 2005, Otx2 regulates subtype specification and neurogenesis in the midbrain, J. Neurosci., 25, 4856, 10.1523/JNEUROSCI.5158-04.2005

Wang, 2005, Math1 expression redefines the rhombic lip derivatives and reveals novel lineages within the brainstem and cerebellum, Neuron, 48, 31, 10.1016/j.neuron.2005.08.024

Watanabe, 2007, A ROCK inhibitor permits survival of dissociated human embryonic stem cells, Nat. Biotechnol., 25, 681, 10.1038/nbt1310

Wataya, 2008, Minimization of exogenous signals in ES cell culture induces rostral hypothalamic differentiation, Proc. Natl. Acad. Sci. USA, 105, 11796, 10.1073/pnas.0803078105

Williams, 2002, Membrane potential bistability is controlled by the hyperpolarization-activated current I(H) in rat cerebellar Purkinje neurons in vitro, J. Physiol., 539, 469, 10.1113/jphysiol.2001.013136

Wingate, 1999, The role of the rhombic lip in avian cerebellum development, Development, 126, 4395, 10.1242/dev.126.20.4395

Yamada, 2014, Specification of spatial identities of cerebellar neuron progenitors by ptf1a and atoh1 for proper production of GABAergic and glutamatergic neurons, J. Neurosci., 34, 4786, 10.1523/JNEUROSCI.2722-13.2014

Zhu, 2002, Role of the chemokine SDF-1 as the meningeal attractant for embryonic cerebellar neurons, Nat. Neurosci., 5, 719, 10.1038/nn881

Zou, 1998, Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development, Nature, 393, 595, 10.1038/31269