Selective Targeting of Vascular Endothelial YAP Activity Blocks EndMT and Ameliorates Unilateral Ureteral Obstruction-Induced Kidney Fibrosis

ACS Pharmacology and Translational Science - Tập 4 Số 3 - Trang 1066-1074 - 2021
Yafeng Ren1, Yuwei Zhang2,3, Lu Wang2,3, Fu‐Qian He4, Mengli Yan1, Xiaoheng Liu2,3, Yangying Ou2,3, Qinkai Wu5, Tao Bi2,3, Shiyuan Wang2,3, Lei Zhu2,3, Bi‐Sen Ding6,7,1, Sheng Wang3, Jie Qing1,2,3
1Key Laboratory of Birth Defects and Related Diseases of Women and Children of MOE, State Key Laboratory of Biotherapy, West China Second University Hospital, Sichuan University, Chengdu, 610064, China
2National Traditional Chinese Medicine Clinical Research Base, Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, 646000, China
3Research Center of Integrated Traditional Chinese and Western Medicine, Affiliated Traditional Medicine Hospital, Southwest Medical University, Luzhou 646000, China
4The Center of Gerontology and Geriatrics and National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University, Chengdu 610041, China
5Michael Smith Laboratories, University of British Columbia, Vancouver, V6T1Z4, Canada
6Ansary Stem Cell Institute, Weill Cornell Medicine, New York, New York 10065, United States
7Fibrosis Research Center, Icahn School of Medicine at Mount Sinai, New York, New York 10128, United States

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Tài liệu tham khảo

10.1172/JCI93563

10.1038/nm.3901

10.1038/s41581-020-0260-2

10.1038/nmat5024

10.1038/nature17040

10.1126/scisignal.aaz2597

10.1681/ASN.2008050513

10.2353/ajpath.2009.090096

10.1681/ASN.2013101137

10.1126/scitranslmed.3006927

10.2337/db09-1631

10.1038/s41580-018-0086-y

10.1038/nrd4161

10.1681/ASN.2015121354

10.1126/scitranslmed.aaz4589

10.1172/JCI93825

10.1038/nature20602

10.1073/pnas.1613121113

10.1101/gad.192856.112

10.1126/scitranslmed.aau6296

10.1681/ASN.2020020220

10.1016/j.cell.2012.06.037

10.1111/j.1476-5381.2011.01434.x

10.1038/nm.3669

10.5137/1019-5149.JTN.27714-19.1

10.1242/dev.175810

10.1385/1-59259-940-0:261

10.1021/acschembio.9b00912

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ACS Pharmacology and Translational Science

Tập 4 Số 3

1066-1074

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