Wellbrock, 2004, The RAF proteins take centre stage, Nat. Rev. Mol. Cell Biol., 5, 875, 10.1038/nrm1498
Wilhelm, 2004, BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis, Cancer Res., 64, 7099, 10.1158/0008-5472.CAN-04-1443
Tanaka, 2008, Interfering with protein–protein interactions: potential for cancer therapy, Cell Cycle, 7, 1569, 10.4161/cc.7.11.6061
Nygren, 2004, Binding proteins from alternative scaffolds, J. Immunol. Methods, 290, 3, 10.1016/j.jim.2004.04.006
Nygren, 2008, Alternative binding proteins: affibody binding proteins developed from a small three-helix bundle scaffold, FEBS J., 275, 2668, 10.1111/j.1742-4658.2008.06438.x
Wahlberg, 2003, An affibody in complex with a target protein: structure and coupled folding, Proc. Natl. Acad. Sci., 100, 3185, 10.1073/pnas.0436086100
Hogbom, 2003, Structural basis for recognition by an in vitro evolved affibody, Proc. Natl. Acad. Sci., 100, 3191, 10.1073/pnas.0436100100
Ruther, 1982, pUR 250 allows rapid chemical sequencing of both DNA strands of its inserts, Nucleic Acids Res., 10, 5765, 10.1093/nar/10.19.5765
Uhlen, 2005, A human protein atlas for normal and cancer tissues based on antibody proteomics, Mol. Cell Proteomics, 4, 1920, 10.1074/mcp.M500279-MCP200
Larsson, 2000, High-throughput protein expression of cDNA products as a tool in functional genomics, J. Biotechnol., 80, 143, 10.1016/S0168-1656(00)00258-3
Nygren, 1988, Analysis and use of the serum albumin binding domains of streptococcal protein G, J. Mol. Recognit., 1, 69, 10.1002/jmr.300010204
Gronwall, 2007, Selection and characterisation of affibody ligands binding to Alzheimer amyloid beta peptides, J. Biotechnol., 128, 162, 10.1016/j.jbiotec.2006.09.013
Nord, 1997, Binding proteins selected from combinatorial libraries of an [alpha]-helical bacterial receptor domain, Nat. Biotechnol., 15, 772, 10.1038/nbt0897-772
Hansson, 1999, An in vitro selected binding protein (affibody) shows conformation-dependent recognition of the respiratory syncytial virus (RSV) G protein, Immunotechnology, 4, 237, 10.1016/S1380-2933(98)00026-8
Orlova, 2006, Tumor imaging using a picomolar affinity HER2 binding affibody molecule, Cancer Res., 66, 4339, 10.1158/0008-5472.CAN-05-3521
Gunneriusson, 1999, Affinity maturation of a Taq DNA polymerase specific affibody by helix shuffling, Protein Eng., 12, 873, 10.1093/protein/12.10.873
Emerson, 1996, Structure of the Ras-binding domain of c-Raf-1 as determined by NMR spectroscopy and identification of the region that interacts with Ras, Drug Des. Discov., 13, 83
Lener, 2000, Diverting a protein from its cellular location by intracellular antibodies. The case of p21Ras, Eur. J. Biochem., 267, 1196, 10.1046/j.1432-1327.2000.01125.x
Tanaka, 2003, Intrabodies based on intracellular capture frameworks that bind the RAS protein with high affinity and impair oncogenic transformation, EMBO J., 22, 1025, 10.1093/emboj/cdg106
Cattaneo, 1999, The selection of intracellular antibodies, Trends Biotechnol., 17, 115, 10.1016/S0167-7799(98)01268-2
Visintin, 2008, In vivo selection of intrabodies specifically targeting protein–protein interactions: a general platform for an ‘undruggable’ class of disease targets, J. Biotechnol., 135, 1, 10.1016/j.jbiotec.2008.02.012
Ronnmark, 2003, Affibody-beta-galactosidase immunoconjugates produced as soluble fusion proteins in the Escherichia coli cytosol, J. Immunol. Methods, 281, 149, 10.1016/j.jim.2003.06.001
Lundberg, 2009, Selection and characterisation of Affibody ligands to the transcription factor c-Jun, Biotechnol. Appl. Biochem., 52, 17, 10.1042/BA20070178
Vernet, 2008, Affinity-based entrapment of the HER2 receptor in the endoplasmic reticulum using an affibody molecule, J. Immunol. Methods, 338, 1, 10.1016/j.jim.2008.06.005
Melchionna, 2007, A protein silencing switch by ligand-induced proteasome-targeting intrabodies, J. Mol. Biol., 374, 641, 10.1016/j.jmb.2007.09.053