Seasonal Weather Changes Affect the Yield and Quality of Recombinant Proteins Produced in Transgenic Tobacco Plants in a Greenhouse Setting
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Baird, 2000, Biochemistry, mutagenesis, and oligomerization of DsRed, a red fluorescent protein from coral, Proc. Natl. Acad. Sci. U. S. A, 97, 11984, 10.1073/pnas.97.22.11984
Bita, 2013, Plant tolerance to high temperature in a changing environment: scientific fundamentals and production of heat stress-tolerant crops, Front. Plant Sci., 4, 273, 10.3389/fpls.2013.00273
Buyel, 2012, Predictive models for transient protein expression in tobacco (Nicotiana tabacum L.) can optimize process time, yield, and downstream costs, Biotechnol. Bioeng., 109, 2575, 10.1002/bit.24523
Buyel, 2014, Flocculation increases the efficacy of depth filtration during the downstream processing of recombinant pharmaceutical proteins produced in tobacco, Plant Biotechnol. J., 12, 240, 10.1111/pbi.12132
Buyel, 2014, Scale-down models to optimize a filter train for the downstream purification of recombinant pharmaceutical proteins produced in tobacco leaves, Biotechnol. J., 9, 415, 10.1002/biot.201300369
Buyel, 2014, Rational design of a host cell protein heat precipitation step simplifies the subsequent purification of recombinant proteins from tobacco, Biochem. Eng. J., 88, 162, 10.1016/j.bej.2014.04.015
Buyel, 2015, Extraction and downstream processing of plant-derived recombinant proteins, Biotechnol. Adv., 33, 902, 10.1016/j.biotechadv.2015.04.010
Buyel, 2017, Very-large-scale production of antibodies in plants: the biologization of manufacturing, Biotechnol. Adv., 35, 458, 10.1016/j.biotechadv.2017.03.011
Debeljak, 2006, Variability in the immunodetection of his-tagged recombinant proteins, Anal. Biochem., 359, 216, 10.1016/j.ab.2006.09.017
Gengenbach, 2018, Expression and purification of human phosphatase and actin regulator 1 (PHACTR1) in plant-based systems, Protein Express. Purif., 151, 46, 10.1016/j.pep.2018.06.003
Goulet, 2019, Production of biopharmaceuticals in Nicotiana benthamiana—axillary stem growth as a key determinant of total protein yield, 10.3389/fpls.2019.00735
Holtz, 2015, Commercial-scale biotherapeutics manufacturing facility for plant-made pharmaceuticals, Plant Biotechnol. J., 13, 1180, 10.1111/pbi.12469
Jutras, 2018, Recombinant protein susceptibility to proteolysis in the plant cell secretory pathway is pH-dependent, Plant Biotechnol. J., 16, 1928, 10.1111/pbi.12928
Ma, 2015, Regulatory approval and a first-in-human phase I clinical trial of a monoclonal antibody produced in transgenic tobacco plants, Plant Biotechnol. J., 13, 1106, 10.1111/pbi.12416
Menzel, 2016, Optimized blanching reduces the host cell protein content and substantially enhances the recovery and stability of two plant-derived malaria vaccine candidates, Front. Plant Sci., 7, 1, 10.3389/fpls.2016.00159
Menzel, 2018, Downstream processing of a plant-derived malaria transmission-blocking vaccine candidate, Protein Express. Purif., 152, 122, 10.1016/j.pep.2018.07.012
Mor, 2015, Molecular pharming’s foot in the FDA’s door: Protalix’s trailblazing story, Biotechnol. Lett., 37, 2147, 10.1007/s10529-015-1908-z
Muster, 1993, A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1, J. Virol., 67, 6642, 10.1128/JVI.67.11.6642-6647.1993
Niemer, 2016, Nicotiana benthamiana cathepsin B displays distinct enzymatic features which differ from its human relative and aleurain-like protease, Biochimie, 122, 119, 10.1016/j.biochi.2015.06.017
Norkunas, 2018, Improving agroinfiltration-based transient gene expression in Nicotiana benthamiana, Plant Methods, 14, 71, 10.1186/s13007-018-0343-2
Opole, 2018, Thresholds, sensitive stages and genetic variability of finger millet to high temperature stress, J. Agron. Crop. Sci., 204, 477, 10.1111/jac.12279
Parker, 2001, Fine definition of the epitope on the gp41 glycoprotein of human immunodeficiency virus type 1 for the neutralizing monoclonal antibody 2F5, J. Virol., 75, 10906, 10.1128/JVI.75.22.10906-10911.2001
Parups, 1960, The growth of tobacco at certain soil temperatures and nutrient levels in greenhouse, Can. J. Plant Sci., 40, 281, 10.4141/cjps60-038
Rühl, 2018, A linear epitope coupled to DsRed provides an affinity ligand for the capture of monoclonal antibodies, J. Chromatogr. A., 1571, 55, 10.1016/j.chroma.2018.08.014
Sack, 2015, The increasing value of plant-made proteins, Curr. Opin. Biotechnol., 32, 163, 10.1016/j.copbio.2014.12.008
Sack, 2015, From gene to harvest: insights into upstream process development for the GMP production of a monoclonal antibody in transgenic tobacco plants, Plant Biotechnol. J., 13, 1094, 10.1111/pbi.12438
Song, 2012, PROSPER: an integrated feature-based tool for predicting protease substrate cleavage sites, Plos One, 7, 10.1371/journal.pone.0050300
Spiegel, 2018, Current status and perspectives of the molecular farming landscape, Molecular pharming: applications, challenges and emerging areas, 3, 10.1002/9781118801512.ch1
Stoger, 2002, Practical considerations for pharmaceutical antibody production in different crop systems, Mol. Breed., 9, 149, 10.1023/A:1019714614827
Wirz, 2012, Automated Production of plant-based vaccines and pharmaceuticals, J. Lab. Autom., 17, 449, 10.1177/2211068212460037
Yamori, 2010, Effects of growth and measurement light intensities on temperature dependence of CO(2) assimilation rate in tobacco leaves, Plant Cell Environ., 33, 332, 10.1111/j.1365-3040.2009.02067.x
Yang, 2018, Effects of different growth temperatures on growth, development, and plastid pigments metabolism of tobacco (Nicotiana tabacum L.) plants, Bot. Studies, 59, 5, 10.1186/s40529-018-0221-2
Zhou, 2017, Physiological response to heat stress during seedling and anthesis stage in tomato genotypes differing in heat tolerance, J. Agron. Crop. Sci., 203, 68, 10.1111/jac.12166