Sclérose en plaques : prévalence de la neurodégénérescence

Compston, 2008, Multiple sclerosis, Lancet, 372, 1502, 10.1016/S0140-6736(08)61620-7 Breij, 2008, Homogeneity of active demyelinating lesions in established multiple sclerosis, Ann Neurol, 63, 16, 10.1002/ana.21311 Disanto, 2012, Evidence for a role of B cells in multiple sclerosis, Neurology, 78, 823, 10.1212/WNL.0b013e318249f6f0 Lublin, 2003, Effect of relapses on development of residual deficit in multiple sclerosis, Neurology, 61, 1528, 10.1212/01.WNL.0000096175.39831.21 Scalfari, 2010, The natural history of multiple sclerosis: a geographically based study 10. Relapses and long-term disability, Brain, 133, 1914, 10.1093/brain/awq118 Leray, 2010, Evidence for a two-stage disability progression in multiple sclerosis, Brain, 133, 1900, 10.1093/brain/awq076 Trojano, 2007, New natural history of interferon-β-treated relapsing multiple sclerosis, Ann. Neurol, 61, 300, 10.1002/ana.21102 Shirani, 2012, Association between use of interferon beta and progression of disability in patients with relapsing-remitting multiple sclerosis, JAMA, 308, 247, 10.1001/jama.2012.7625 Fisher, 2008, Gray matter atrophy in multiple sclerosis: a longitudinal study, Ann Neurol, 64, 255, 10.1002/ana.21436 Calabrese, 2013, The changing clinical course of multiple sclerosis: a matter of gray matter, Ann Neurol, 74, 76, 10.1002/ana.23882 Deloire, 2011, MRI predictors of cognitive outcome in early multiple sclerosis, Neurology, 76, 1161, 10.1212/WNL.0b013e318212a8be De Stefano, 2010, Assessing brain atrophy rates in a large population of untreated multiple sclerosis subtypes, Neurology, 74, 1868, 10.1212/WNL.0b013e3181e24136 De Stefano, 1998, Axonal damage correlates with disability in patients with relapsing-remitting multiple sclerosis. Results of a longitudinal magnetic resonance spectroscopy study, Brain, 121, 1469, 10.1093/brain/121.8.1469 Evangelou, 2000, Quantitative pathological evidence for axonal loss in normal appearing white matter in multiple sclerosis, Ann Neurol, 47, 391, 10.1002/1531-8249(200003)47:3<391::AID-ANA20>3.0.CO;2-J Kuhlmann, 2002, Acute axonal damage in multiple sclerosis is most extensive in early disease stages and decreases over time, Brain, 125, 2202, 10.1093/brain/awf235 Ferguson, 1997, Axonal damage in acute multiple sclerosis, Brain, 120, 393, 10.1093/brain/120.3.393 Trapp, 1998, Axonal transection in the lesions of multiple sclerosis, N Engl J Med, 38, 278, 10.1056/NEJM199801293380502 Griffiths, 1998, Axonal swellings and degeneration in mice lacking the major proteolipid of myelin, Science, 280, 1610, 10.1126/science.280.5369.1610 Craner, 2004, Molecular changes in neurons in multiple sclerosis: altered axonal expression of Nav1.2 and Nav1.6 sodium channels and Na+/Ca2+ exchanger, Proc Natl Acad Sci U S A, 101, 8168, 10.1073/pnas.0402765101 Lucchinetti, 2000, Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination, Ann Neurol, 47, 707, 10.1002/1531-8249(200006)47:6<707::AID-ANA3>3.0.CO;2-Q Barnett, 2004, Relapsing and remitting multiple sclerosis: pathology of the newly forming lesion, Ann Neurol, 55, 458, 10.1002/ana.20016 Peterson, 2001, Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions, Ann Neurol, 50, 389, 10.1002/ana.1123