Scientific evidence and common sense as a basis for food-packaging regulations

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Davis, 1962, Tumorigenic potential of aldrin and dieldrin for mice, Toxic. appl. Pharmac., 4, 187, 10.1016/0041-008X(62)90056-X

Hercules Incorporated (Unpublished data).

Lehman, 1965

Hazleton, 1964, Safety evaluation studies on 2,5-dichloro-3-aminobenzoic acid (Amiben), Toxic. appl. Pharmac., 6, 349

Sherman, 1965, Toxicity studies on ammonium sulfamate, Toxic. appl. Pharmac., 7, 497

Lehman, 1952, Vol. XVI, 47

Prier, 1963, The toxicity of an organic arsenical, 3-nitro-4-hydroxyphenylarsonic acid. II. Chronic Toxicity, Toxic. appl. Pharmac., 5, 526, 10.1016/0041-008X(63)90024-3

Fitzhugh, 1946, Subacute and chronic toxicities of ascorbyl palmitates, 61, 195

Joint FAO/WHO Expert Committee on Food Additives—Sixth Report, 1962, Evaluation of the Toxicity of a Number of Antimicrobials and Antioxidants, Tech. Rep. Ser. Wld Hlth Org., 228

Oser, 1965, Studies of the safety of azodicarbonamide as a flour-maturing agent, Toxic appl. Pharmac., 7, 445, 10.1016/0041-008X(65)90146-8

Deichmann, 1955, Toxicity of ditertiarybutylmethylphenol, A.M.A. Archs ind. Hlth, 11, 93

Joint FAO/WHO Expert Committee on Food Additives—Ninth Report, 1966, Specifications for the Identity and Purity of Food Additives and their Toxicological Evaluation: Some Antimicrobials, Antioxidants, Emulsifiers, Stabilizers, Flour-Treatment Agents, Acids and Bases, Tech. Rep. Ser. Wld Hlth Org., 339

Lehman, 1955, Vol. 19, 87

Scala, 1964, Safety evaluation studies on 1,3-butylene glycol, Toxic. appl. Pharmac., 6, 358

Oser, 1962, 2-(p-tert-Butylphenoxy)isopropyl 2-chloroethlyl sulfite (Aramite). II. Carcinogenicity, Toxic. appl. Pharmac., 4, 70, 10.1016/0041-008X(62)90077-7

Oser, 1963, Safety evaluation studies of calcium EDTA, Toxic. appl. Pharmac., 5, 142, 10.1016/0041-008X(63)90039-5

Oser, 1966, Carcinogenicity study of carbarsone, Toxic. appl. Pharmac., 9, 528, 10.1016/0041-008X(66)90014-7

Shelanski, 1948, Physiological action of sodium carboxymethylcellulose on laboratory animals and humans, Fd Res., 13, 29, 10.1111/j.1365-2621.1948.tb16591.x

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Lehman, 1951, The pharmacological evaluation of antioxidants, Adv. Fd Res., 3, 197, 10.1016/S0065-2628(08)60261-X

Delahunt, 1960, Prolonged administration studies with chlorpropamide, Toxic. appl. Pharmac., 2, 195, 10.1016/0041-008X(60)90049-1

Dessau, 1961, A two-year study of the toxicity of chlortetracycline hydrochloride in rats, Toxic. appl. Pharmac., 3, 654, 10.1016/0041-008X(61)90030-8

Dacre, 1965, Chronic toxicity and carcinogenicity studies on Citrus Red No. 2, 43, 31

Hansen, 1965, Chronic toxicity of cubé, Toxic. appl. Pharmac., 7, 535, 10.1016/0041-008X(65)90038-4

Industrial Bio-Test Laboratories (Unpublished data).

Davis, 1962, Pathologic changes noted in rats fed D & C Red No. 9 for two years, Toxic. appl. Pharmac., 4, 200, 10.1016/0041-008X(62)90058-3

Davis, 1963, Pathologic changes noted in rats fed D & C Red No. 10 [monosodium salt of 2-(2-hydroxy-1-naphthylazo)-1-naphthalenesulfonic acid] for two years, Toxic. appl. Pharmac., 5, 728, 10.1016/0041-008X(63)90065-6

American Cyanamid Company (Unpublished data).

Hodge, 1962, Chronic oral toxicity studies of di-n-hexyl azelate in rats and dogs, Toxic. appl. Pharmac., 4, 247, 10.1016/0041-008X(62)90063-7

Smyth, 1966, Toxicologic studies on 3,5-dimethyltetrahydro-1,3,5, 2H-thiadiazine-2-thione, a soil fungicide and slimicide, Toxic. appl. Pharmac., 9, 521, 10.1016/0041-008X(66)90013-5

Kerr, 1965, Evaluation of the safety of 3,5-dinitrobenzamide, Toxic. appl. Pharmac., 7, 488

Ambrose, 1960, A toxicological study of biphenyl, a citrus fungistat, Fd Res., 25, 328, 10.1111/j.1365-2621.1960.tb00338.x

Paynter, 1960, Chronic toxicity of Santomerase No. 3 from olefin (dodecyl benzene sodium sulfonate), Toxic. appl. Pharmac., 2, 641, 10.1016/0041-008X(60)90082-X

Levinskas, 1961, Acute and chronic toxicity of dodine (n-dodecylguanidine acetate), Toxic. appl. Pharmac., 3, 127, 10.1016/0041-008X(61)90016-3

Larson, 1960, Chronic toxicity studies on two epoxidized soybean oils in the rat and dog, Toxic. appl. Pharmac., 2, 649, 10.1016/0041-008X(60)90083-1

Fitzhugh, 1951, A comparison of the chronic toxicities of synthetic sweetening agents, J. Am. pharm. Ass. Sci Ed., 40, 583, 10.1002/jps.3030401117

Borzelleca, 1964, Studies on the chronic oral toxicity of monomeric ethyl acrylate and methyl methacrylate, Toxic. appl. Pharmac., 6, 29, 10.1016/0041-008X(64)90019-5

Treon, 1953, Toxicity of 2-ethylhexyl diphenyl phosphate, A.M.A. Archs ind. Hyg., 8, 170

Hansen, 1966, Chronic toxicity of three food colourings: Guinea Green B, Light Green SF Yellowish and Fast Green FCF in rats, dogs and mice, Fd Cosmet. Toxicol., 4, 389, 10.1016/S0015-6264(66)80581-3

Hansen, 1966, Chronic toxicity of two food colours, Brilliant Blue FCF and Indigotine, Toxic. appl. Pharmac., 8, 29, 10.1016/0041-008X(66)90097-4

Hine, 1953, Comparative toxicity of synthetic and natural glycerin, A.M.A. Archs ind. Hyg., 7, 282

Ames, 1951, Molecularly distilled monoglycerides, III. Nutritional studies on monoglycerides derived from cottonseed oil, J. Am. Oil Chem. Soc., 28, 31, 10.1007/BF02639747

Johnson, 1938, Action of gum guaiacum upon the animal organism, Fd Res., 3, 555, 10.1111/j.1365-2621.1938.tb17092.x

Frawley, 1965, Investigations establishing the safety of rosin products for food, food packaging applications, Nav. Stores Rev. Ter. Chem., 74, 4

Paynter, 1966, Toxicologic evaluation of the n-heptyl ester of p-hydroxybenzoic acid, Toxic. appl. Pharmac., 8, 350

Smyth, 1947, Chronic toxicity of hydroxyethyl cellulose for rats, J. Am. pharm. Ass., 36, 335, 10.1002/jps.3030361104

Larson, 1960, Chronic toxicologic studies on isopropyl N-(3-chlorophenyl) carbamate (CIPC), Toxic. appl. Pharmac., 2, 659, 10.1016/0041-008X(60)90084-3

Hodge, 1952, Chronic oral toxicity tests of methoxychlor [2, 2-di-(p-methoxyphenyl)-1,1,1-trichloroethane] in rats and dogs, J. Pharmac. exp. Ther., 104, 60

McCollister, 1965, Toxicology of 4-tert-butyl-2-chlorophenyl methyl methylphosphoramidate (Ruelene), Toxic. appl. Pharmac., 7, 490

Matthews, 1956, p-Hydroxybenzoic acid esters as preservatives, II: Acute and chronic toxicity in dogs, rats and mice, J. Am. pharm. Ass., 45, 260, 10.1002/jps.3030450420

Webb, 1963, Chronic and subacute toxicology and pathology of methyl salicylate in dogs, rats, and rabbits, Toxic. appl. Pharmac., 5, 576, 10.1016/0041-008X(63)90003-6

Fitzhugh, 1947, Chronic oral toxicity of alpha-naphthyl thiourea, 64, 305

Haskell Laboratories, DuPont Company (Unpublished data).

MacDonald, 1962, The chronic toxicity of octadecylamine in the rat—a supplemental report, Toxic. appl. Pharmac., 4, 610, 10.1016/0041-008X(62)90087-X

Larson, 1963, Toxicologic studies on a preparation of p-tertiary octylphenoxy-polyethoxy ethanols (Triton X-405), Toxic. appl. Pharmac., 5, 782, 10.1016/0041-008X(63)90070-X

Oser, 1965, Toxicologic studies of petrolatum in mice and rats, Toxic. appl. Pharmac., 7, 382, 10.1016/0041-008X(65)90140-7

Shubik, 1962, Studies on the toxicity of petroleum waxes, Toxic. appl. Pharmac., 4, 49, 10.1016/0041-008X(62)90112-6

Woodard, 1965, Phenacetin: Long-term studies in rats and dogs, Toxic. appl. Pharmac., 7, 503

Hodge, 1952, Toxicological studies of ortho-phenylphenol in (Dowicide I), J. Pharmac. exp. Ther., 104, 202

Levinskas, 1966, Acute and chronic toxicity of pimaricin, Toxic. appl. Pharmac., 8, 97, 10.1016/0041-008X(66)90105-0

McCollister, 1965, Toxicologic investigations of polyacrylamides, Toxic. appl. Pharmac., 7, 639, 10.1016/0041-008X(65)90119-5

Joint FAO/WHO Expert Committee on Food Additives—Seventh Report, 1964, Specifications for the Identity and Purity of Food Additives and Their Toxicological Evaluation: Emulsifiers, Stabilizers, Bleaching and Maturing Agents, Tech. Rep. Ser. Wld Hlth Org., 281

Fitzhugh, 1959, Chronic oral toxicities of four stearic acid emulsifiers, Toxic. appl. Pharmac., 1, 315, 10.1016/0041-008X(59)90116-4

Hansen, 1963, Chronic oral toxicity of Ponceau 3R, Toxic. appl. Pharmac., 5, 105, 10.1016/0041-008X(63)90085-1

Davis, 1966, Chronic toxicity of Ponceau SX to rats, mice and dogs, Toxic. appl. Pharmac., 8, 306, 10.1016/S0041-008X(66)80017-0

Nilson, 1951, Feeding tests with some algin products, 76, 630

Tusing, 1960, The chronic toxicity of sodium alkylbenzenesulfonate by food and water administration to rats, Toxic. appl. Pharmac., 2, 464, 10.1016/0041-008X(60)90013-2

Fitzhugh, 1946, Chronic toxicity of sulfites, J. Pharmac. exp. Ther., 86, 37

Food and Drug Administration (Unpublished data).

Fitzhugh, 1948, Chronic oral toxicities of surface-active agents, J. Am. pharm. Ass. Sci. Ed., 37, 29, 10.1002/jps.3030370109

Tusing, 1962, Toxicologic studies on sodium lauryl glyceryl ether sulfonate and sodium lauryl trioxyethylene sulfate, Toxic. appl. Pharmac., 4, 402, 10.1016/0041-008X(62)90050-9

Lehman, 1958, Nitrates and nitrites in meat products, Q. Bull. Ass. Fd Drug Off. U.S., 22, 136

Fitzhugh, 1947, The comparative chronic toxicities of fumaric, tartaric, oxalic and maleic acids, J. Am. pharm. Ass. Sci. Ed., 36, 217, 10.1002/jps.3030360708

Davis, 1964, Chronic rat and dog toxicity studies on tartrazine, Toxic. appl. Pharmac., 6, 621, 10.1016/0041-008X(64)90095-X

Fitzhugh, 1948, Liver tumours in rats fed thiourea or thioacetamide, Science, N.Y., 108, 626, 10.1126/science.108.2814.626

Carson, 1964, Toxicologic studies with the antioxidant Polygard, Toxic. appl. Pharmac., 6, 342

Anderson, 1965, Toxicological studies on Tylosin: Its safety as a food additive, Toxic. appl. Pharmac., 7, 478

Smyth, 1966, Chronic oral toxicity to rats of a vinyl chloride-vinyl acetate copolymer, Toxic. appl. Pharmac., 9, 501, 10.1016/0041-008X(66)90010-X

Hansen, 1963, Chronic toxicity of Yellow AB (1-phenylazo-2-naphthylamine) and Yellow OB (1-o-tolylazo-2-naphthylamine), Toxic. appl. Pharmac., 5, 16, 10.1016/0041-008X(63)90079-6