Schistosoma mansoni: TGF-β signaling pathways

Experimental Parasitology - Tập 117 Số 3 - Trang 304-317 - 2007
Philip T. LoVerde1, Ahmed M. Osman, Andrew P. Hinck
1Department of Biochemistry, University of Texas Health Science Center, San Antonio, TX 78229-3900, USA. [email protected]

Tóm tắt

Từ khóa


Tài liệu tham khảo

Allendorph, 2006, Structure of the ternary signaling complex of a TGF-beta superfamily member, Proc. Natl. Acad. Sci. USA, 103, 7643, 10.1073/pnas.0602558103

Annes, 2003, Making sense of latent TGFbeta activation, J. Cell Sci., 116, 217, 10.1242/jcs.00229

Armstrong, 1965, Mating behavior and development of schistosomes in the mouse, J. Parasitol., 51, 605, 10.2307/3276242

Aronstein, 1985, A glycoprotein antigen of Schistosoma mansoni expressed on the gynecophoral canal of mature male worms, Am. J. Trop. Med. Hyg., 34, 508, 10.4269/ajtmh.1985.34.508

Bannister, 1996, The CBP co-activator is a histone acetyltransferase, Nature, 384, 641, 10.1038/384641a0

Beall, 2000, Functional conservation of Schistosoma mansoni Smads in TGF beta signaling, Mol. Biochem. Parasitol., 111, 131, 10.1016/S0166-6851(00)00307-8

Beall, 2000, Functional conservation of Schistosoma mansoni Smads in TGF-beta signaling, Mol. Biochem. Parasitol., 111, 131, 10.1016/S0166-6851(00)00307-8

Beall, 2001, Human transforming growth factor-beta activates a receptor serine/threonine kinase from the intravascular parasite Schistosoma mansoni, J. Biol. Chem., 276, 31613, 10.1074/jbc.M104685200

Bertin, 2006, Schistosoma mansoni CBP/p300 has a conserved domain structure and interacts functionally with the nuclear receptor SmFtz-F1, Mol. Biochem. Parasitol., 146, 180, 10.1016/j.molbiopara.2005.12.006

Blank, 2006, The common γ chain cytokines Interleukin (IL)-2 and IL-7 indirectly modulate blood fluke development via effects on CD4+ T cells, J. Infect. Dis., 194, 1609, 10.1086/508896

Bostic, 1996, Molecular cloning of a Schistosoma mansoni protein expressed in the gynecophoral canal of male worms, Mol. Biochem. Parasitol., 79, 79, 10.1016/0166-6851(96)02640-0

Carlo, J.M., Osman, A., Niles, E.G., Wu, W., Fantappie, M.R., Oliveira, F.M., Lo Verde, P.T., 2007. Identification and Characterization of a R-Smad orthologue (SmSmad1B) from Schistosoma mansoni. FEBS J., in press.

Chen, 1997, Mechanism of TGFbeta receptor inhibition by FKBP12, EMBO J., 16, 3866, 10.1093/emboj/16.13.3866

Clough, 1981, Morphology and reproductive organs and oogenesis in bisexual and unisexual transplants of mature Schistosoma mansoni females, J. Parasitol., 67, 535, 10.2307/3280487

Davies, 2003, Developmental plasticity in schistosomes and other helminths, Int. J. Parasitol., 33, 1277, 10.1016/S0020-7519(03)00161-9

Davies, 1995, Surface-associated serine–threonine kinase in Schistosoma mansoni, Mol. Biochem. Parasitol., 70, 33, 10.1016/0166-6851(95)00002-I

Davies, 1999, Atypical post-translational modification and targeting of a Schistosoma mansoni surface receptor, a member of the transforming growth factor beta receptor family of cell surface receptors, Mol. Biochem. Parasitol., 104, 299, 10.1016/S0166-6851(99)00147-4

Davies, 1998, A divergent member of the transforming growth factor beta receptor family from Schistosoma mansoni is expressed on the parasite surface membrane, J. Biol. Chem., 273, 11234, 10.1074/jbc.273.18.11234

de Moraes Maciel, 2004, Schistosoma mansoni histone acetyltransferase GCN5: linking histone acetylation to gene activation, Mol. Biochem. Parasitol., 133, 131, 10.1016/j.molbiopara.2003.09.005

Derynck, 1996, Nomenclature: vertebrate mediators of TGFbeta family signals, Cell, 87, 173, 10.1016/S0092-8674(00)81335-5

Derynck, 2003, Smad-dependent and Smad-independent pathways in TGF-beta family signalling, Nature, 425, 577, 10.1038/nature02006

Dissous, 2006, Growth factor receptors in helminth parasites: signalling and host-parasite relationships, FEBS Lett., 580, 2968, 10.1016/j.febslet.2006.03.046

Dubois, 1995, Processing of transforming growth factor beta 1 precursor by human furin convertase, J. Biol. Chem., 270, 10618, 10.1074/jbc.270.18.10618

Ellenrieder, 2001, Transforming growth factor beta1 treatment leads to an epithelial–mesenchymal transdifferentiation of pancreatic cancer cells requiring extracellular signal-regulated kinase 2 activation, Cancer Res., 61, 4222

Eppert, 1996, MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma, Cell, 86, 543, 10.1016/S0092-8674(00)80128-2

Erasmus, 1973, A comparative study of the reproductive system of mature, immature and “unisexual” female Schistosoma mansoni, Parasitology, 67, 165, 10.1017/S0031182000046394

Erasmus, 1987

Escobedo, 2005, Parasite regulation by host hormones: an old mechanism of host exploitation?, Trends Parasitol., 21, 588, 10.1016/j.pt.2005.09.013

Feng, 1997, A kinase subdomain of transforming growth factor-beta (TGF-beta) type I receptor determines the TGF-beta intracellular signaling specificity, EMBO J., 16, 3912, 10.1093/emboj/16.13.3912

Feng, 2005, Specificity and versatility in tgf-beta signaling through Smads, Annu. Rev. Cell Dev. Biol., 21, 659, 10.1146/annurev.cellbio.21.022404.142018

Ferguson, 2003, Developmental expression patterns of Beta-ig (betaIG-H3) and its function as a cell adhesion protein, Mech. Dev., 120, 851, 10.1016/S0925-4773(03)00165-5

Forrester, 2004, Tegumental expression of a novel type II receptor serine/threonine kinase (SmRK2) in Schistosoma mansoni, Mol. Biochem. Parasitol., 136, 149, 10.1016/j.molbiopara.2004.03.007

Freitas, 2007, TGF-beta signaling controls embryo development in the parasitic flatworm Schistosoma mansoni, PLoS Pathog, 3, e52, 10.1371/journal.ppat.0030052

Graff, 1996, Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily, Cell, 85, 479, 10.1016/S0092-8674(00)81249-0

Greenwald, 1999, Three-finger toxin fold for the extracellular ligand-binding domain of the type II activin receptor serine kinase, Nat. Struct. Biol., 6, 18, 10.1038/4887

Greenwald, 2003, The BMP7/ActRII extracellular domain complex provides new insights into the cooperative nature of receptor assembly, Mol. Cell, 11, 605, 10.1016/S1097-2765(03)00094-7

Groppe, J.C., Zuniga, J., Hinck, C.S., Samavarchi-Tehrani, P., Wrana, J., Hinck, A.P., 2006. Structure of TGF-beta complexed to its type I and type II receptors, Cell, submitted for publication.

Harrison, 2004, An activin mutant with disrupted ALK4 binding blocks signaling via type II receptors, J. Biol. Chem., 279, 28036, 10.1074/jbc.M402782200

Hart, 2002, Crystal structure of the human TbetaR2 ectodomain–TGF-beta3 complex, Nat. Struct. Biol., 9, 203

Hayashida, 2003, Cross-talk between ERK MAP kinase and Smad signaling pathways enhances TGF-beta-dependent responses in human mesangial cells, FASEB J., 17, 1576, 10.1096/fj.03-0037fje

Heldin, 1997, TGF-beta signalling from cell membrane to nucleus through SMAD proteins, Nature, 390, 465, 10.1038/37284

Hernandez, 2004, Schistosoma mansoni: sex-specific modulation of parasite growth by host immune signals, Exp. Parasitol., 106, 59, 10.1016/j.exppara.2004.01.003

Huse, 1999, Crystal structure of the cytoplasmic domain of the type I TGF beta receptor in complex with FKBP12, Cell, 96, 425, 10.1016/S0092-8674(00)80555-3

Huse, 2001, The TGF beta receptor activation process: an inhibitor- to substrate-binding switch, Mol. Cell, 8, 671, 10.1016/S1097-2765(01)00332-X

Kahata, 2004, Regulation of transforming growth factor-beta and bone morphogenetic protein signalling by transcriptional coactivator GCN5, Genes Cells, 9, 143, 10.1111/j.1365-2443.2004.00706.x

Kirsch, 2000, BMP-2 antagonists emerge from alterations in the low-affinity binding epitope for receptor BMPR-II, EMBO J., 19, 3314, 10.1093/emboj/19.13.3314

Kirsch, 2000, Crystal structure of the BMP-2-BRIA ectodomain complex, Nat. Struct. Biol., 7, 492, 10.1038/75903

Kloos, 2002, The TGF-beta–Smad network: introducing bioinformatic tools, Trends Genet., 18, 96, 10.1016/S0168-9525(02)02556-8

Knobloch, J., Beckmann, S., Burmeister, C., Quack, T., Grevelding, C.G., 2007. Tyrosine kinase signaling in the reproductive organs of Schistosoma mansoni. Exp. Parasitol., in press.

Knobloch, 2006, Herbimycin A suppresses mitotic activity and egg production of female Schistosoma mansoni, Int. J. Parasitol., 36, 1261, 10.1016/j.ijpara.2006.06.004

Knobloch, 2004, Cytological and biochemical evidence for a gonad-preferential interplay of SmFKBP12 and SmTbetaR-I in Schistosoma mansoni, Mol. Biochem. Parasitol., 138, 227, 10.1016/j.molbiopara.2004.09.006

Kretzschmar, 1997, Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1, Nature, 389, 618, 10.1038/39348

Kretzschmar, 1999, A mechanism of repression of TGFbeta/Smad signaling by oncogenic Ras, Genes Dev., 13, 804, 10.1101/gad.13.7.804

Labbe, 1998, Smad2 and Smad3 positively and negatively regulate TGF beta-dependent transcription through the forkhead DNA-binding protein FAST2, Mol. Cell, 2, 109, 10.1016/S1097-2765(00)80119-7

Lo, 1998, The L3 loop: a structural motif determining specific interactions between SMAD proteins and TGF-beta receptors, EMBO J., 17, 996, 10.1093/emboj/17.4.996

LoVerde, 2002, Sex and Schistosomes: an interesting biological interplay with control implications, J. Parasitol., 88, 3, 10.1645/0022-3395(2002)088[0003:PASASA]2.0.CO;2

LoVerde, 2002, Presidential address. Sex and schistosomes: an interesting biological interplay with control implications, J. Parasitol., 88, 3, 10.1645/0022-3395(2002)088[0003:PASASA]2.0.CO;2

LoVerde, 1991, Schistosome female reproductive development, Parasitol. Today, 7, 303, 10.1016/0169-4758(91)90263-N

LoVerde, 2004, Schistosoma mansoni male–female interactions, Can. J. Zool., 82, 357, 10.1139/z03-217

Massague, 1998, TGF-beta signal transduction, Annu. Rev. Biochem., 67, 753, 10.1146/annurev.biochem.67.1.753

Massague, 2000, Transcriptional control by the TGF-beta/Smad signaling system, EMBO J., 19, 1745, 10.1093/emboj/19.8.1745

McGonigle, 2001, Conserved role for 14-3-3epsilon downstream of type I TGFbeta receptors, FEBS Lett., 490, 65, 10.1016/S0014-5793(01)02133-0

McGonigle, 2002, Eukaryotic initiation factor 2 alpha subunit associates with TGF beta receptors and 14-3-3 epsilon and acts as a modulator of the TGF beta response, Biochemistry, 41, 579, 10.1021/bi011407z

McGonigle, 2001, SIP, a novel SH3 domain-containing protein, interacts with Schistosoma mansoni receptor kinase 1, Mol. Biochem. Parasitol., 114, 119, 10.1016/S0166-6851(01)00232-8

McGonigle, 2002, 14-3-3 Proteins in Schistosoma mansoni; identification of a second epsilon isoform, Int. J. Parasitol., 32, 685, 10.1016/S0020-7519(01)00323-X

Michaels, 1969, Mating of Schistosoma mansoni in vitro, Exp. Parasitol., 25, 58, 10.1016/0014-4894(69)90052-6

Moore, 1954, The relationship of male worms to the sexual development of female Schistosoma mansoni, J. Parasitol., 40, 166, 10.2307/3274297

Nakao, 1997, Identification of Smad2, a human Mad-related protein in the transforming growth factor beta signaling pathway, J. Biol. Chem., 272, 2896, 10.1074/jbc.272.5.2896

Neves, 2005, A new description of the reproductive system of Schistosoma mansoni (Trematoda: Schistosomatidae) analyzed by confocal laser scanning microscopy, Parasitol. Res., 95, 43, 10.1007/s00436-004-1241-2

Osman, 2001, Identification and characterization of a Smad2 homologue from Schistosoma mansoni, a transforming growth factor-beta signal transducer, J. Biol. Chem., 276, 10072, 10.1074/jbc.M005933200

Osman, 2004, Expression of functional Schistosoma mansoni Smad4: role in Erk-mediated transforming growth factor beta (TGF-beta) down-regulation, J. Biol. Chem., 279, 6474, 10.1074/jbc.M310949200

Osman, 2006, Schistosoma mansoni TGF-beta receptor II: role in host ligand-induced regulation of a schistosome target gene, PLoS Pathog, 2, e54, 10.1371/journal.ppat.0020054

Popiel, 1986, The reproductive biology of schistosomes, Parasitol. Today, 2, 10, 10.1016/0169-4758(86)90068-2

Popiel, 1984, Reproductive development of female Schistosoma mansoni (Digenea: Schistosomatidae) following bisexual pairing of worms and worm segments, J. Exp. Zool., 232, 141, 10.1002/jez.1402320117

Ramachandran, 1996, The Schistosoma mansoni epidermal growth factor receptor homologue, SER, has tyrosine kinase activity and is localized in adult muscle, Mol. Biochem. Parasitol., 83, 1, 10.1016/S0166-6851(96)02731-4

Riggins, 1996, Mad-related genes in the human, Nat. Genet., 13, 347, 10.1038/ng0796-347

Salzet, 2000, Molecular crosstalk in host–parasite relationships: schistosome– and leech–host interactions, Parasitol. Today, 16, 536, 10.1016/S0169-4758(00)01787-7

Shaw, 1977, Schistosoma mansoni: pairing in vitro and development of females from single sex infections, Exp. Parasitol., 41, 54, 10.1016/0014-4894(77)90129-1

Shi, 2003, Mechanisms of TGF-beta signaling from cell membrane to the nucleus, Cell, 113, 685, 10.1016/S0092-8674(03)00432-X

Shi, 1998, Crystal structure of a Smad MH1 domain bound to DNA: insights on DNA binding in TGF-beta signaling, Cell, 94, 585, 10.1016/S0092-8674(00)81600-1

Suzuki, 2007, Transforming growth factor beta signaling via Ras in mesenchymal cells requires p21-activated kinase 2 for extracellular signal-regulated kinase-dependent transcriptional responses, Cancer Res., 67, 3673, 10.1158/0008-5472.CAN-06-3211

Thompson, 2003, Structures of an ActRIIB:activin A complex reveal a novel binding mode for TGF-beta ligand:receptor interactions, EMBO J., 22, 1555, 10.1093/emboj/cdg156

Tsukazaki, 1998, SARA, a FYVE domain protein that recruits Smad2 to the TGF b receptor, Cell, 95, 779, 10.1016/S0092-8674(00)81701-8

Verjovski-Almeida, 2003, Transcriptome analysis of the acoelomate human parasite Schistosoma mansoni, Nat. Genet., 35, 148, 10.1038/ng1237

Vicogne, 2004, Conservation of epidermal growth factor receptor function in the human parasitic helminth Schistosoma mansoni, J. Biol. Chem., 279, 37407, 10.1074/jbc.M313738200

Vogel, 1941, Zentralblalt fur Bakteriologie Parasitenkunde I, Abt. Orig., 148, 178

Wang, 1996, The immunophilin FKBP12 functions as a common inhibitor of the TGF beta family type I receptors, Cell, 86, 435, 10.1016/S0092-8674(00)80116-6

Wolowczuk, 1997, Interleukin-7 in the skin of Schistosoma mansoni-infected mice is associated with a decrease in interferon-gamma production and leads to an aggravation of the disease, Immunology, 91, 35, 10.1046/j.1365-2567.1997.00229.x

Wolowczuk, 1999, Infection of mice lacking interleukin-7 (IL-7) reveals an unexpected role for IL-7 in the development of the parasite Schistosoma mansoni, Infect. Immun., 67, 4183, 10.1128/IAI.67.8.4183-4190.1999

Wolowczuk, 1999, Role of interleukin-7 in the relation between Schistosoma mansoni and its definitive vertebrate host, Microbes Infect., 1, 545, 10.1016/S1286-4579(99)80094-X

Wu, 2000, Structural basis of Smad2 recognition by the Smad anchor for receptor activation, Science, 287, 92, 10.1126/science.287.5450.92

Xu, 2002, Smad2 nucleocytoplasmic shuttling by nucleoporins CAN/Nup214 and Nup153 feeds TGFbeta signaling complexes in the cytoplasm and nucleus, Mol. Cell, 10, 271, 10.1016/S1097-2765(02)00586-5

Zhang, 1996, Receptor-associated Mad homologues synergize as effectors of the TGF-beta response, Nature, 383, 168, 10.1038/383168a0

Zhang, Y., Feng, X.H., Derynck, R., 1998. Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription [published erratum appears in Nature 1998 Dec 3;396(6710):491]. Nature 394, 909–913.

Zuniga, 2005, Assembly of TbetaRI:TbetaRII:TGFbeta ternary complex in vitro with receptor extracellular domains is cooperative and isoform-dependent, J. Mol. Biol., 354, 1052, 10.1016/j.jmb.2005.10.014