Satellite glia not DRG neurons constitutively activate EGFR but EGFR inactivation is not correlated with axon regeneration

Neurobiology of Disease - Tập 39 - Trang 292-300 - 2010
Zubair Ahmed1, Martin L. Read1, Martin Berry1, Ann Logan1
1Molecular Neuroscience Group, Neuropharmacology and Neurobiology Section, School of Clinical and Experimental Medicine, University of Birmingham, Birmingham, B15 2TT, UK

Tài liệu tham khảo

Ahmed, 2005, Disinhibition of neurotrophin-induced dorsal root ganglion cell neurite outgrowth on CNS myelin by siRNA-mediated knockdown of NgR, p75(NTR) and Rho-A, Mol. Cell. Neurosci., 28, 509, 10.1016/j.mcn.2004.11.002 Ahmed, 2006, TACE-induced cleavage of NgR and p75NTR in dorsal root ganglion cultures disinhibits outgrowth and promotes branching of neurites in the presence of inhibitory CNS myelin, FASEB J., 20, 1939, 10.1096/fj.05-5339fje Ahmed, 2006, Schwann cell-derived factor-induced modulation of the NgR/p75(NTR)/EGFR axis disinhibits axon growth through CNS myelin in vivo and in vitro, Brain, 129, 1517, 10.1093/brain/awl080 Ahmed, 2009, ROCK inhibition promotes adult retinal ganglion cell neurite outgrowth only in the presence of growth promoting factors, Mol. Cell. Neurosci., 42, 128, 10.1016/j.mcn.2009.06.005 Ahmed, 2009, Epidermal growth factor receptor inhibitors promote CNS axon growth through off-target effects on glia, Neurobiol. Dis., 36, 142, 10.1016/j.nbd.2009.07.016 Bahr, 1995, Myelin from peripheral and central nervous system is a nonpermissive substrate for retinal ganglion cell axons, Exp. Neurol., 134, 87, 10.1006/exnr.1995.1039 Berry, 2008, Regeneration of axons in the visual system, Restor. Neurol. Neurosci., 26, 147 Bomze, 2001, Spinal axon regeneration evoked by replacing two growth cone proteins in adult neurons, Nat. Neurosci., 4, 38, 10.1038/82881 Chong, 1999, Axonal regeneration from injured dorsal roots into the spinal cord of adult rats, J. Comp. Neurol., 410, 42, 10.1002/(SICI)1096-9861(19990719)410:1<42::AID-CNE5>3.0.CO;2-F Costigan, 2002, Replicate high-density rat genome oligonucleotide microarrays reveal hundreds of regulated genes in the dorsal root ganglion after peripheral nerve injury, BMC Neurosci., 3, 16, 10.1186/1471-2202-3-16 Douglas, 2009, Off-target effects of epidermal growth factor receptor antagonists mediate retinal ganglion cell disinhibited axon regeneration, Brain, 132, 3102, 10.1093/brain/awp240 Du, 2007, Eph/ephrin signaling as a potential therapeutic target after central nervous system injury, Curr. Pharm. Des., 13, 2507, 10.2174/138161207781368594 Erschbamer, 2007, Inhibiting epidermal growth factor receptor improves structural, locomotor, sensory, and bladder recovery from experimental spinal cord injury, J. Neurosci., 27, 6428, 10.1523/JNEUROSCI.1037-07.2007 Fabes, 2007, Regeneration-enhancing effects of EphA4 blocking peptide following corticospinal tract injury in adult rat spinal cord, Eur. J. Neurosci., 26, 2496, 10.1111/j.1460-9568.2007.05859.x Fischer, 2004, Switching mature retinal ganglion cells to a robust growth state in vivo: gene expression and synergy with RhoA inactivation, J. Neurosci., 24, 8726, 10.1523/JNEUROSCI.2774-04.2004 Fournier, 2002, Nogo and the Nogo-66 receptor, Prog. Brain Res., 137, 361, 10.1016/S0079-6123(02)37027-4 Gomezpinilla, 1988, Epidermal growth-factor receptor immunoreactivity in rat-brain — development and cellular-localization, Brain Res., 438, 385, 10.1016/0006-8993(88)91369-8 Hokfelt, 1987, Increase of galanin-like immunoreactivity in rat dorsal root ganglion cells after peripheral axotomy, Neurosci. Lett., 83, 217, 10.1016/0304-3940(87)90088-7 Holmes, 2000, Targeted disruption of the galanin gene reduces the number of sensory neurons and their regenerative capacity, Proc. Natl. Acad. Sci. U. S. A., 97, 11563, 10.1073/pnas.210221897 Hou, 2008, Permissive and repulsive cues and signalling pathways of axonal outgrowth and regeneration, Int. Rev. Cell Mol. Biol., 267, 125, 10.1016/S1937-6448(08)00603-5 Hunt, 2002, The Nogo receptor, its ligands and axonal regeneration in the spinal cord; a review, J. Neurocytol., 31, 93, 10.1023/A:1023941421781 Jin, 2002, Heparin-binding epidermal growth factor-like growth factor: hypoxia-inducible expression in vitro and stimulation of neurogenesis in vitro and in vivo, J. Neurosci., 22, 5365, 10.1523/JNEUROSCI.22-13-05365.2002 Koprivica, 2005, EGFR activation mediates inhibition of axon regeneration by myelin and chondroitin sulfate proteoglycans, Science, 310, 106, 10.1126/science.1115462 Lagord, 2002, Expression of TGFbeta2 but not TGFbeta1 correlates with the deposition of scar tissue in the lesioned spinal cord, Mol. Cell. Neurosci., 20, 69, 10.1006/mcne.2002.1121 Lisovoski, 1997, Transforming growth factor alpha expression as a response of murine motor neurons to axonal injury and mutation-induced degeneration, J. Neuropathol. Exp. Neurol., 56, 459, 10.1097/00005072-199705000-00001 Liu, 2003, Activation of epidermal growth factor receptor signals induction of nitric oxide synthase-2 in human optic nerve head astrocytes in glaucomatous optic neuropathy, Neurobiol. Dis., 13, 109, 10.1016/S0969-9961(03)00010-X Liu, 2004, Activation of epidermal growth factor receptors directs astrocytes to organize in a network surrounding axons in the developing rat optic nerve, Dev. Biol., 273, 297, 10.1016/j.ydbio.2004.06.006 Liu, 2006, Epidermal growth factor receptor activation: an upstream signal for transition of quiescent astrocytes into reactive astrocytes after neural injury, J. Neurosci., 26, 7532, 10.1523/JNEUROSCI.1004-06.2006 McKerracher, 2001, Spinal cord repair: strategies to promote axon regeneration, Neurobiol. Dis., 8, 11, 10.1006/nbdi.2000.0359 McKerracher, 2002, Nogo on the go, Neuron, 36, 345, 10.1016/S0896-6273(02)01018-8 Neumann, 1999, Regeneration of dorsal column fibers into and beyond the lesion site following adult spinal cord injury, Neuron, 23, 83, 10.1016/S0896-6273(00)80755-2 Peng, 2010, Mechanical stretch-induced RhoA activation is mediated by the RhoGEF Vav2 in mesangial cells, Cell Signal., 22, 34, 10.1016/j.cellsig.2009.09.003 Planas, 1998, Epidermal growth factor receptor in proliferating reactive glia following transient focal ischemia in the rat brain, Glia, 23, 120, 10.1002/(SICI)1098-1136(199806)23:2<120::AID-GLIA3>3.0.CO;2-A Quarles, 2009, A hypothesis about the relationship of myelin-associated glycoprotein's function in myelinated axons to its capacity to inhibit neurite outgrowth, Neurochem. Res., 34, 79, 10.1007/s11064-008-9668-y Sandvig, 2004, Myelin-, reactive glia-, and scar-derived CNS axon growth inhibitors: expression, receptor signaling, and correlation with axon regeneration, Glia, 46, 225, 10.1002/glia.10315 Seijffers, 2007, ATF3 increases the intrinsic growth state of DRG neurons to enhance peripheral nerve regeneration, J. Neurosci., 27, 7911, 10.1523/JNEUROSCI.5313-06.2007 Shim, 2010, Roles of channels and receptors in the growth cone during PNS axonal regeneration, Exp. Neurol., 223, 38, 10.1016/j.expneurol.2009.10.001 Smith, 2005, Growth factor and cytokine regulation of chondroitin sulfate proteoglycans by astrocytes, Glia, 52, 209, 10.1002/glia.20236 Wakisaka, 1991, Increased neuropeptide Y (NPY)-like immunoreactivity in rat sensory neurons following peripheral axotomy, Neurosci. Lett., 124, 200, 10.1016/0304-3940(91)90093-9 Wakisaka, 1992, Effects of peripheral nerve injuries and tissue inflammation on the levels of neuropeptide Y-like immunoreactivity in rat primary afferent neurons, Brain Res., 598, 349, 10.1016/0006-8993(92)90206-O White, 1998, Contribution of neurotrophin-3 to the neuropeptide Y-induced increase in neurite outgrowth of rat dorsal root ganglion cells, Neuroscience, 86, 257, 10.1016/S0306-4522(98)00034-7 White, 1996, Vasoactive intestinal polypeptide and neuropeptide Y act indirectly to increase neurite outgrowth of dissociated dorsal root ganglion cells, Neuroscience, 73, 881, 10.1016/0306-4522(96)00055-3 Woolf, 2001, Turbocharging neurons for growth: accelerating regeneration in the adult CNS, Nat. Neurosci., 4, 7, 10.1038/82921 Zhang, 1995, Ultrastructural studies on peptides in the dorsal horn of the rat spinal cord—IV. Effects of peripheral axotomy with special reference to neuropeptide Y and vasoactive intestinal polypeptide/peptide histidine isoleucine, Neuroscience, 64, 917, 10.1016/0306-4522(94)00487-P