Safety evaluation of surgical materials by cytotoxicity testing

Tsuchiya T, Ikarashi Y, Hata H, Toyoda K, Takahashi M, Uchima T, Tanaka N, Sasaki T, Nakamura A. Comparative studies of the toxicity of standard reference materials in various cytotoxicity tests and in vivo implantation tests. J Appl Biomater 1993;4:153–156

Kooten van TG, Klein LC, Wagner M, Kirkpatrick JC. Focal adhesion and assessment of cytotoxicity. J Biomed Mater Res 1999;46:33–43

Nappi JF, Lehman JA. The effect of Surgicel on bone formation. Cleft Palate J 1980;17:291–296

Ibarrola JL, Bjorenson JE, Austin BP, Gerstein H. Osseous reactions to three hemostatic agents. J Endodont 1985;11:75–83

Matthew IR, Browne RM, Frame JW, Millar BG. Subperiosteal behavior of alginate and cellulose wound dressing materials. Biomaterials 1995;16:75–78

Krishnan LK, Mohanty M, Umashankar PR, Lal AV. Comparative evaluation of absorbable hemostats: advantages of fibrin-based sheets. Biomaterials 2004;24:5557–5563

Dutton JJ, Tse DT, Anderson RL. Compressive optic neuropathy following use of intracranial oxidized cellulose hemostat. Ophthal Surg 1983;14:487–490

Inoue M, Uchida K, Miki C, Kusunoki M. Efficacy of Seprafilm for reducing reoperative risk in pediatric patients undergoing abdominal surgery. J Pediatr Surg 2005;40:1301–1306

Tomizawa Y, Komori M, Takada K, Nishida H, Endo M, Kurosawa H. In vitro and in vivo evaluation of the biocompatibility and cytotoxicity of local hemostatic agents. Jpn J Cardiovasc Surg 2004;33:382–386

US Food and Drug Administration. http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfMAUDE/search.cfm?searchoptions=1

Tsuchiya T, Arai T, Ohhashi J, Imai K, Kokima H, Miyamoto S, Hata H, Ikarashi Y, Toyoda K, Takahashi M, Nakamura A. Rabbit eye irritation caused by wearing toxic contact lenses and their cytotoxicities: in vivo/in vitro correlation study using standard reference materials. J Biomed Mater Res 1993;27:885–893