Safety, efficacy, and biomarker findings of PBT2 in targeting Aβ as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial

The Lancet Neurology - Tập 7 Số 9 - Trang 779-786 - 2008
Lars Lannfelt1, Kaj Blennow2, Henrik Zetterberg2, Stellan Båtsman3, David Ames4, John Harrison5,6, Colin L. Masters7, Steve Targum8, Ashley I. Bush7, Ross Murdoch9, Janet Wilson9, Craig Ritchie6
1Department of Public Health and Geriatrics, Uppsala University Hospital, Uppsala, Sweden
2Clinical Neurochemistry Laboratory, Sahlgren's University Hospital, Mölndal, Sweden
3Vårdcentralen Kalix, Kalix, Sweden
4National Ageing Research Institute and University of Melbourne Academic Unit for Psychiatry of Old Age, Melbourne, Australia
5Cogstate Ltd, Warminster, UK
6Department of Psychological Medicine, Imperial College London, London, UK
7Mental Health Research Institute, The University of Melbourne, Melbourne, Australia
8Massachusetts General Hospital, Boston, MA, USA
9Prana Biotechnology, Melbourne, Australia

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