Safety and efficacy of the JAK inhibitor tofacitinib citrate in patients with alopecia areata

JCI insight - Tập 1 Số 15 - 2016
Milène K. Crispin1, Justin Ko1, Brittany G. Craiglow2,3, Shufeng Li1, Gautam Shankar1, J. Urban4, James C. Chen2,5, Jane Cerise2, Ali Jabbari2, M.C.G. Winge1, M. Peter Marinkovich1, Angela M. Christiano2,6, Anthony E. Oro1, Brett King2
1Program in Epithelial Biology and Department of Dermatology, Stanford University School of Medicine, Stanford, California, USA
2Department of Dermatology
3‡Department of Pediatrics and
4Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut USA
5Department of Systems Biology, and
6Department of Genetics and Development, Columbia University, New York, New York, USA

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Tài liệu tham khảo

10.4065/70.7.628

Delamere, 2008, Interventions for alopecia areata, Cochrane database Syst Rev, 10.1002/14651858.CD004413.pub2

10.1038/nature09114

Betz, 2015, Genome-wide meta-analysis in alopecia areata resolves HLA associations and reveals two new susceptibility loci, Nat Commun, 6, 10.1038/ncomms6966

10.1038/nm.3645

10.1038/jid.2014.260

10.1016/j.ebiom.2015.02.015

10.1016/S0140-6736(14)62113-9

10.1016/j.cels.2015.11.001

10.1002/art.38779

10.1016/S0140-6736(12)61424-X

10.1002/art.37816

10.1056/NEJMoa1310476

10.1056/NEJMoa1110557

10.1126/sciadv.1500973

Mackay-Wiggan, 2016, Oral ruxolitinib induces hair regrowth in patients with moderate to severe alopecia areata, JCI Insight, 1, 10.1172/jci.insight.89790

Olsen, 1999, Alopecia areata investigational assessment guidelines. National Alopecia Areata Foundation, J Am Acad Dermatol, 40, 242, 10.1016/S0190-9622(99)70195-7

Colevas, 2004, The NCI Common Terminology Criteria for Adverse Events (CTCAE) v 3.0 is the new standard for oncology clinical trials, J Clin Oncol (meeting abstracts), 22

10.1093/nar/30.1.207