SETting the Stage for Cancer Development: SETD2 and the Consequences of Lost Methylation
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2011, Scientific report, Nat Publ Gr, 12, 463
2015, Loss of MLH1 confers resistance to PI3Kβ inhibitors in renal clear cell carcinoma with SETD2 mutation, Tumour Biol, 36, 3457, 10.1007/s13277-014-2981-y
2015, High-resolution profiling of histone h3 lysine 36 trimethylation in metastatic renal cell carcinoma, Oncogene, 35, 1565
2005, Risk of tumorigenesis in overgrowth syndromes: A comprehensive review, Am J Med Genet-Semin Med Genet, 137C, 53, 10.1002/ajmg.c.30064
2016, Functional studies on primary tubular epithelial cells indicate a tumor suppressor role of SETD2 in clear cell renal cell carcinoma, Neoplasia, 18, 339, 10.1016/j.neo.2016.04.005
2016, Genomic profiling of malignant phyllodes tumors reveals aberrations in FGFR1 and PI-3 kinase/RAS signaling pathways and provides insights into intratumoral heterogeneity, Mod Pathol, 29, 1012, 10.1038/modpathol.2016.97
2014, Mutations in epigenetic regulators including SETD2 are gained during relapse in paediatric acute lymphoblastic leukaemia, Nat Commun, 5, 3469, 10.1038/ncomms4469
2010, Evidence for a tumour suppressor function of SETD2 in human breast cancer: A new hypothesis, Anticancer Res, 30, 3309
2015, Inhibiting WEE1 selectively kills histone H3K36me3-deficient cancers by dNTP starvation, Cancer Cell, 28, 557, 10.1016/j.ccell.2015.09.015
2010, Mechanism and regulation of DNA end resection in eukaryotes, Crit Rev Biochem Mol Biol, 51, 195
2016, Dynamic reprogramming of DNA methylation in SETD2-deregulated renal cell carcinoma, Oncotarget, 7, 1927, 10.18632/oncotarget.6481
2016, Prognostic value of SETD2 expression in patients with metastatic renal cell carcinoma treated with tyrosine kinase inhibitors, J Urol, 195, 1363
2015, miR-106b-5p targets tumor suppressor gene SETD2 to inactive its function in clear cell renal cell carcinoma, Oncotarget, 6, 4066, 10.18632/oncotarget.2926
2014, H3K36 histone methyltransferase Setd2 is required for murine embryonic stem cell differentiation toward endoderm, Cell Rep, 8, 1989, 10.1016/j.celrep.2014.08.031