SENSORY NEUROPEPTIDES AND RHEUMATIC DISEASES

Agro, 1992, Are lymphocytes a target for substance P modulation in arthritis?, Semin Arthritis Rheum, 21, 252, 10.1016/0049-0172(92)90056-J Amalich, 1992, Sensory and sympathetic neuropeptides and cytokines in human inflammatory arthritis [abstract], Arthritis Rheum, 35, d27 Appelboom, 1991, Enkephalinase: A physiologic neuromodulator detected in the synovial fluid, Arthritis Rheum, 34, 1048, 10.1002/art.1780340815 Bathon, 1992, Cultured human synovial fibroblasts rapidly metabolize kinins and neuropeptide, J Clin Invest, 90, 981, 10.1172/JCI115975 Bayliss, 1901, On the origin from the spinal cord of the vasodilator fibres of the hind limb, and on the nature of these fibres, J Physiol (Lond), 26, 173, 10.1113/jphysiol.1901.sp000831 Bienenstock, 1989, Evidence for mast cell-nerve interactions, 275 Bost, 1992, Substance P: A late acting B lymphocyte differentiation cofactor, Am J Physiol, 262, C537, 10.1152/ajpcell.1992.262.3.C537 Boudard, 1991, Inhibition of mouse T cell proliferation by CGRP and VIP: Effects of these neuropeptides on IL-2 production and cAMP synthesis, J Neurosci Res, 29, 29, 10.1002/jnr.490290104 Brain, 1992, Evidence that CGRP contributes to inflammation in the skin and in joints, Ann N Y Acad Sci, 165, 412, 10.1111/j.1749-6632.1992.tb22787.x Brain, 1985, Inflammatory edema induced by synergism between calcitonin gene related peptide and mediators of increased vascular permeability, Br J Pharmacol, 86, 655, 10.1111/j.1476-5381.1985.tb11107.x Bruce, 1910, Uber die bezieehung der sensiblen nervendigungen zun entzundungsvorgang, Archder Experimental Patholologie und Pharmakologie, 63, 424, 10.1007/BF01840938 Buckley, 1991, Inflammatory edema induced by interactions between IL-1 and the neuropeptide calcitonin gene related peptide, J Immunol, 146, 10.4049/jimmunol.146.10.3424 Calvo, 1992, Substance P enhances IL-2 expression in activated human T cells, J Immunol, 148, 10.4049/jimmunol.148.11.3498 Chrubasik, 1984, Somatostatin, a potent analgesic, Lancet, 2, 1208, 10.1016/S0140-6736(84)92761-2 Colpaert, 1983, Effects of capsaicin on inflammation and on the substance P content of nervous tissues in rats with adjuvant arthritis, Life Sci, 32, 1827, 10.1016/0024-3205(83)90060-7 Denko, 1985, Effects of peptide hormones in urate crystal inflammation, J Rheumatol, 12, 971 Devillier, 1983, Elevated levels of tachykinin like immunoreactivity in joint fluids from patients with rheumatic inflammatory diseases, N Engl J Med, 314, 1323 Ehlers, 1989, Angiotensin converting enzyme: New concepts concerning its biological role, Biochemistry, 28, 10.1021/bi00439a001 Ferrel, 1986, Extravasation in the knee induced by antidromic stimulatin of articular C fibre afferents of the anaesthetized cat, J Physiol (Lond), 379, 407, 10.1113/jphysiol.1986.sp016260 Foster, 1992, Calcitonin gene related peptide is chemotactic for human T lymphocytes, Ann N Y Acad Sci, 657, 397, 10.1111/j.1749-6632.1992.tb22785.x Gazelius, 1981, Evidence that substance P is a mediator of antidromic vasodilatation using somatostatin as a release inhibitor, Acta Physiol Scand, 113, 155, 10.1111/j.1748-1716.1981.tb06876.x Goetzl, 1984, Inhibition by somatostatin of the release of mediators from human basophils and rat leukemic basophils, J Immunol, 133, 10.4049/jimmunol.133.6.3255 Gronblad, 1988, Neuropeptides in synovium of patients with rheumatoid arthritis and osteoarthritis, J Rheumatol, 15, 1897 Hafstrom, 1989, Substance P activates and modulates neutrophil oxidative metabolism and aggregation, J Rheumatol, 16, 1033 Haegerstrand, 1990, Calcitonin gene related peptide stimulates proliferation of human endothelial cells, Proc Natl Acad Sci USA, 87, 10.1073/pnas.87.9.3299 Hartung, 1983, Activation of macrophages by substance P: Induction of oxidative burst and thromboxane release, Eur J Pharmacol, 89, 301, 10.1016/0014-2999(83)90511-3 Holzer, 1988, Local effector functions of capsaicin sensitive sensory nerves endings: Involvement of tachykinins, CGRP and other neuropeptides, Neuroscience, 24, 739, 10.1016/0306-4522(88)90064-4 Inman, 1989, Neuromodulation of synovitis: The capsaicin effect on severity of experimental arthritis, J Neuroimmunol, 24, 17, 10.1016/0165-5728(89)90093-3 Jancsò, 1967, Direct evidence for neurogenic inflammation and its prevention by denervation and by pretreatment with capsaicin, Br J Pharmacol, 31, 138 Johansson, 1987, Stimulative effect of somatostatin on cell proliferation in culture synoviocytes, Medical Biology, 65, 57 Jorizzo, 1983, Vascular responses of human skin to injection of substance P and mechanism of action, Eur J Pharmacol, 87, 67, 10.1016/0014-2999(83)90051-1 Khalil, 1990, Serotonin modulates substance P-induced plasma extravasation in rat skin by an action through capsaicin sensitive primary afferent nerves, Brain Res, 527, 292, 10.1016/0006-8993(90)91149-B Kidd, 1992, Role of sympathetic nervous system in chronic joint pain and inflammation, Ann Rheum Dis, 51, 1188, 10.1136/ard.51.11.1188 Kidd, 1990, Neurogenic influences in arthritis, Ann Rheum Dis, 49, 649, 10.1136/ard.49.8.649 Klimiuk, 1988, Autonomic neuropathy in systemic sclerosis, Ann Rheum Dis, 47, 542, 10.1136/ard.47.7.542 Kolasinski, 1992, Neuropeptides and inflammation: A somatostatin analog as a selective antagonist of neutrophil activation by substance P, Arthritis Rheum, 35, 369, 10.1002/art.1780350402 Kurahishi, 1985, Evidence that Substance P and somatostatin transmit separate information related to pain in the spinal dorsal horn, Brain Res, 325, 294, 10.1016/0006-8993(85)90326-9 Larsson, 1991, Concentration of substance P, Neurokinin A, CGRP, neuropeptide Y and VIP in synovial fluid from knee joints in patients suffering from rheumatoid arthritis, Scand J Rheumatol, 20, 326, 10.3109/03009749109096808 Lembeck, 1988, Substance P: From extract to excitement, Acta Physiol Scand, 133, 435, 10.1111/j.1748-1716.1988.tb08427.x Lembeck, 1981, Increase of substance P in primary afferent nerves during chronic pain, Neuropeptides, 1, 175, 10.1016/0143-4179(81)90013-5 Lembeck, 1979, Substance P as a neurogenic mediator of antidromic vasodilation and neurogenic plasma extravasation, Naunyn Schmiedebergs Arch Pharmacol, 310, 175, 10.1007/BF00500282 Levine, 1984, Intraneuronal substance P contributes to the severity of experimental arthritis, Science, 226, 547, 10.1126/science.6208609 Levine, 1988, The effect of gold, an antirheumatic therapy, on substance P levels in rat peripheral nerve, Neuroscience, 87, 280 Levine, 1985, Hypothesis: The nervous system may contribute to the pathophysiology of rheumatoid arthritis, J Rheumatol, 12, 406 Levine, 1986, Contribution of sensory afferents and sympathetic efferents to joint injury in experimental arthritis, J Neurosci, 6, 10.1523/JNEUROSCI.06-12-03423.1986 Levine, 1985, The contribution of neurogenic inflammation in experimental arthritis, J Immunol, 135, 843s, 10.4049/jimmunol.135.2.843 Llorens-Cortes, 1992, Identification and characterization of neutral endopeptidase in endothelial cells from venous and arterial origin, J Biol Chem, 267, 10.1016/S0021-9258(19)49671-3 Lorkowski, 1987, Neutral endopeptidase 24–11 (enkephalinase). Biosynthesis and localization in human fibroblasts, Biochem J, 248, 345, 10.1042/bj2480345 Lotz, 1987, Substance P activation of rheumatoid synoviocytes: Neural pathway in the pathogenesis of rheumatoid arthritis, Science, 235, 893, 10.1126/science.2433770 Lotz, 1988, Effects of neuropeptides on production of inflammatory cytokines by human monocytes, Science, 241, 1218, 10.1126/science.2457950 Lotz, 1992, Effects of topical capsaicin (0.075%) on substance P and prostaglandin E2 in synovial fluid: a double blind study, Arthritis Rheum, 35, d132 Louis, 1990, Immunization with CGRP peptide reduces the inflammatory response to adjuvant arthritis in the rat, Neuroscience, 39, 727, 10.1016/0306-4522(90)90256-4 Lowe, 1986, Serum and synovial fluid levels of angiotensin converting enzyme in polyarthritis, Ann Rheum Dis, 45, 921, 10.1136/ard.45.11.921 Maggi, 1991, The pharmacology of the efferent function of sensory nerves, J Auton Pharmacol, 11, 173, 10.1111/j.1474-8673.1991.tb00317.x Mapp, 1990, Substance P, CGRP and c-flanking peptide of neuropeptide Y immunoreactive fibres are present in normal synovium but depleted in patients with rheumatoid arthritis, Neuroscience, 37, 14, 10.1016/0306-4522(90)90199-E Marshall, 1990, Substance P and arthritis: Analysis of plasma and synovial fluid levels, Arthritis Rheum, 33, 87, 10.1002/art.1780330111 Matis, 1990, Substance P induces the expression of ELAM by microvascular endothelium, J Invest Dermatol, 94, 492, 10.1111/1523-1747.ep12874665 Matucci-Cerinic, 1992, angiotensin converting enzyme. An in vivo and in vitro marker of endothelial injury, J Lab Clin Med, 128, 428 Matucci-Cerinic, 1993, Neutral endopeptidase in plasma and synovial fluid of patients with rheumatoid arthritis. A marker of disease activity or a regulator of pain and inflammation?, Rheumatol Int, 13, 1, 10.1007/BF00290326 Matucci-Cerinic, 1988, Somatostatin treatment of psoriatic arthritis, Int J Dermatol, 27, 56, 10.1111/j.1365-4362.1988.tb02341.x Matucci-Cerinic, 1988, Somatostatin treatment for pain in rheumatoid arthritis: A double blind versus placebo study in knee involvement, Medical Science Research, 16, 233 Matucci-Cerinic, 1991, Somatostatin activity in experimental arthritis (abstract 264), 260 Matucci-Cerinic, 1992, The contribution of the peripheral nervous system and the neuropeptide network to the development of synovial inflammation, Clin Exp Rheumatol, 10, 211 Matucci-Cerinic, 1991, High levels of substance P in rheumatoid arthritis synovial fluid. Lack of substance P production by synoviocytes in vitro, Clin Exp Rheumatol, 9, 440 Matucci-Cerinic, 1990, Local venomotor response to intravenous infusion of substance P and glyceryl trinitrate in systemic sclerosis, Clin Exp Rheumatol, 8, 561 Matucci-Cerinic, 1992, Gold salts and somatostatin: A new combined analgesic treatment for psoriatic arthritis, Drugs Exp Clin Res, 18, 53 Matucci-Cerinic, 1990, Reduced angiotensin converting enzyme plasmatic activity in scleroderma. A marker of endothelial injury?, J Rheumatol, 17, 328 Matucci-Cerinic, 1992, Neutral endopeptidase (3.4.24.11:enkephalinase) levels in systemic sclerosis, Br J Rheumatol, 31, 17 Menkes CJ, Renoux M, Laoussadi S, et al: Substance P levels in the synovium and synovial fluid from rheumatoid arthritis and osteoarthritis. J Rheumatol, in press Milner, 1990, Endothelial cells cultured from human umbilical vein release ATP, substance P and acethylcholine in response to increased flow, Proc R Soc Lond [Biol], 241, 245, 10.1098/rspb.1990.0092 Mione, 1990, Peptides and vasomotor mechanisms, Pharmacol Ther, 46, 429, 10.1016/0163-7258(90)90027-Y Muscettola, 1990, Somatostatin and VIP reduce interferon gamma production by human peripheral blood mononuclear cells, Immunobiology, 180, 419, 10.1016/S0171-2985(11)80303-7 Nadel, 1991, Modulation of neurogenic inflammation by neutral endopeptidase, Am Rev Respir Dis, 143, s33, 10.1164/ajrccm/143.3_Pt_2.S33 Nilsson, 1985, Stimulation of connective tissue cell growth by substance P and substance K, Science, 315, 61 Nong, 1989, Peptides encoded by calcitonin gene inhibit macrophage function, J Immunol, 143, 45, 10.4049/jimmunol.143.1.45 O’Byrne, 1990, Elevated substance P and accelerated cartilage degradation in rabbit knees injected with interleukin 1 and tumor necrosis factor, Arthritis Rheum, 33, 1023, 10.1002/art.1780330715 O’Byrne, 1991, Effects of indomethacin, triamcinolone and dexamethasone and recombinant interleukin 1-induced substance P and prostaglandin E2 levels in rabbit knee joints, Agents Action, 34, 46, 10.1007/BF01993234 Ohlen, 1989, Substance P activates leucocytes and platelets in rabbit microvessels, Blood Vessels, 26, 84 Partsch, 1992, Effects of substance P and somatotatin on migration of polymorphonuclear cells in vitro, Inflammation, 16, 539, 10.1007/BF00918978 Partsch, 1991, Collagenase synthesis of rheumatoid arthritis synoviocytes: Dose dependent stimulation by substance P and capsaicin, Scand J Rheumatol, 20, 98, 10.3109/03009749109165283 Patel, 1990, Mechanism of action of somatostatin: An overview of receptor function and studies of the molecular characterization and purification of somatostatin receptor protein, Metabolism, 9, 63, 10.1016/0026-0495(90)90214-W Pawlowski, 1963, The nerve network of the skin in diffuse scleroderma and clinically similar conditions, Arch Dermatol, 88, 236, 10.1001/archderm.1963.01590240192032 Pawlikoski, 1987, Immunomodulatory action of somatostatin, Ann N Y Acad Sci, 496, 233, 10.1111/j.1749-6632.1987.tb35771.x Payan, 1989, Neuropeptides and inflammation: The role of substance P, Annu Rev Med, 40, 341, 10.1146/annurev.me.40.020189.002013 Payan, 1985, Receptor mediated mitogenic effects of substance P on cultured smooth muscle cells, Biochem Biophys Res Commun, 130, 109, 10.1016/0006-291X(85)90388-2 Payan, 1985, Modulation of lymphocyte function by sensory neuropeptides, J Immunol, 135, 783S, 10.4049/jimmunol.135.2.783 Payan, 1984, Inhibition by somatostatin of the proliferation of T lymphocytes and Molt 4 lymphocytes, Cell Immunol, 84, 433, 10.1016/0008-8749(84)90117-5 Pereira da Silva, 1990, Peptide containing nerves in human synovium: Immunohistochemical evidence for decreased innervation in rheumatoid arthritis, J Rheumatol, 17, 1592 Polak, 1986, Somatostatin localization in tissues, Scand J Gastroenterol, 119, 11, 10.3109/00365528609087427 Raud, 1991, Potent antinflammatory action of calcitonin gene related peptide, Biochem Biophys Res Commun, 180, 1429, 10.1016/S0006-291X(05)81356-7 Scarborough, 1990, Somatostatin regulation by cytokines, Metabolism, 39, 108, 10.1016/0026-0495(90)90224-Z Schady, 1991, Peripheral nerve dysfunction in scleroderma, Q J Med, 80, 661 Schally, 1988, Oncological applications of somatostatin analogues, Cancer Res, 48 Scicchitano, 1987, In vivo immunomodulation by the neuropeptide substance P, Immunology, 63, 733 Shipp, 1990, Downregulation of enkephalin mediated inflammatory responses by CD10/neutral endopeptidase 24.11, Nature, 347, 394, 10.1038/347394a0 Sicuteri, 1984, Pain relief by somatostatin in attacks of cluster headache, Pain, 18, 359, 10.1016/0304-3959(84)90048-4 Skidgel, 1987, Angiotensin I converting enzyme and its role in neuropeptide metabolism, 165 Smallridge, 1986, Angiotensin coverting enzyme: Characteristics in human skin fibroblasts, Metabolism, 35, 899, 10.1016/0026-0495(86)90051-X Solis-Cohen, 1911, Certain angioneurotic manifestations in and around joints frequently mistaken for gout and rheumatism, Transactions of the College of Physicians of Philadelphia, 33, 309 Sreedharan, 1990, Elevated synovial tissue concentration of the acute common acute lymphoblastic leukemia antigen (CALLA) associated neutral endopeptidase (3.4.24.11) in human chronic arthritis, Immunology, 71, 142 Stanisz, 1986, Differential effects of vasoactive intestinal polypeptide, substance P, and somatostatin on immunoglobulin synthesis and proliferation by lymphocytes from Peyer’s patches, mesenteric lymphnodes and spleen, J Immunol, 136, 152, 10.4049/jimmunol.136.1.152 Stricker, 1876, Untersuchungen uber die gefarsswurzeln des ischiadichus, Sber Akademie Wissenschaft Wien, 3, 173 Sung, 1992, CGRP stimulates the adhesion of leukocytes to vascular endothelial cells, Peptides, 13, 429, 10.1016/0196-9781(92)90071-A Terenghi, 1988, Image analysis quantification of peptide-immunor-eactive nerves in the skin of patients with Raynaud’s phenomenon and systemic sclerosis, J Pathol, 164, 245, 10.1002/path.1711640310 Theoharides, 1981, Mast cell histamine secretion in response to somatostatin analogues: Structural considerations, Eur J Pharmacol, 73, 131, 10.1016/0014-2999(81)90084-4 Turner, 1987, Endopeptidases 24–11 and neuropeptide metabolism, 183 Umeda, 1989, Inhibition of natural killer activity by calcitonin gene related peptide, Immunopharmacol Immunotoxicol, 11, 309, 10.3109/08923978909005372 Veale, 1992, Production of angiotensin converting enzyme by rheumatoid synovial membrane, Ann Rheum Dis, 51, 476, 10.1136/ard.51.4.476 Walsh, 1992, Localisation and characterisation of substance P binding to human synovial tissue in rheumatoid arthritis, Ann Rheum Dis, 51, 313, 10.1136/ard.51.3.313 Wallengren, 1987, Occurrence and distribution of neuropeptides in the human skin, Acta Derm Venereol (Stockh), 67, 185, 10.2340/0001555567185192 Yaksh, 1988, Substance P release from knee joint afferent terminals: Modulation by opioids, Brain Res, 458, 319, 10.1016/0006-8993(88)90474-X Ziche, 1990, Substance P stimulation of neovascularization in vivo and proliferation of cultured endothelial cells, Microvasc Res, 40, 264, 10.1016/0026-2862(90)90024-L