SARS-CoV, MERS-CoV and SARS-CoV-2 infections in pregnancy and fetal development

Journal of Gynecology Obstetrics and Human Reproduction - Tập 49 Số 10 - Trang 101846 - 2020
Guilherme Antonio de Souza Silva1, Suéllen Pedrosa da Silva2, Marcos Aurélio Santos da Costa3, Abdênego Rodrigues da Silva2, Robson Raion de Vasconcelos Alves2, Fernanda das Chagas Ângelo Mendes Tenório3, Alanne Rayssa da Silva Melo4, Antônio Carlos de Freitas4, Cristiane Moutinho Lagos de Melo1
1Laboratory of Immunological and Antitumor Analysis, Department of Antibiotics, Bioscience Center, Federal University of Pernambuco, Brazil
2Laboratory of Protein Biochemistry, Department of Biochemistry, Bioscience Center, Federal University of Pernambuco, Brazil
3Laboratory of Histology, Department of Histology and Embryology, Bioscience Center, Federal University of Pernambuco, Brazil
4Laboratory of Molecular Studies and Experimental Therapy, Department of Genetics, Bioscience Center, Federal University of Pernambuco, Brazil

Tóm tắt

Từ khóa


Tài liệu tham khảo

Berger, 2004, Severe acute respiratory syndrome (SARS)—paradigm of an emerging viral infection, J Clin Virol, 29, 13, 10.1016/j.jcv.2003.09.011

Wong, 2004, Pregnancy and perinatal outcomes of women with severe acute respiratory syndrome, Am J Obstet Gynecol, 191, 292, 10.1016/j.ajog.2003.11.019

Ng, 2016, The placentas of patients with severe acute respiratory syndrome: a pathophysiological evaluation, Pathology, 38, 210, 10.1080/00313020600696280

Omrani, 2014, Ribavirin and interferon alfa-2a for severe Middle East respiratory syndrome coronavirus infection: a retrospective cohort study, Lancet Infect Dis, 14, 1090, 10.1016/S1473-3099(14)70920-X

Lai, 2020, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and corona virus disease-2019 (COVID-19): the epidemic and the challenges, Int J Antimicrob Agents, 55, 10.1016/j.ijantimicag.2020.105924

Payne, 2014, Stillbirth during infection with Middle East respiratory syndrome coronavirus, J Infect Dis, 209, 1870, 10.1093/infdis/jiu068

Malik, 2013, Middle east respiratory syndrome coronavirus during pregnancy, Abu Dhabi, United Arab Emirates, Emerg Infect Dis, 2016, 515

Chan, 2020, Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan, Emerg Microbes Infect, 9, 221, 10.1080/22221751.2020.1719902

Li, 2020, Early transmission dynamics in Wuhan, China, of novel coronavirus–infected pneumonia, N Engl J Med, 382, 1199, 10.1056/NEJMoa2001316

Mardani, 2020, Controversial Debate: Vertical transmission of COVID-19 in pregnancy, Arch Clin Infect Dis, 15, e102286, 10.5812/archcid.102286

Vasylyeva, 2020, Pregnancy and COVID-19, a brief review, Int J Integr Pediatr Environ Med, 5, 8

Robertson, 2004, SARS and pregnancy: a case report, Emerging Infect Dis, 10, 345, 10.3201/eid1002.030736

WHO, 2003

WHO, 2003

Muller, 2015, Presence of Middle East respiratory syndrome coronavirus antibodies in Saudi Arabia: a nationwide, cross-sectional, serological study, Lancet Infect Dis, 15, 629

Meo, 2020, Novel coronavirus 2019-nCoV: prevalence, biological and clinical characteristics comparison with SARS-CoV and MERS-CoV, Eur Rev Med Pharmacol Sci, 24, 2012

Kandeel, 2014, Bioinformatics analysis of the recent MERS-coV with special reference to the virus-encoded spike protein, Mol Enzymol Drug Targets, 1, 1

Choi, 2017, Progress of Middle East respiratory syndrome coronavirus vaccines: a patent review, Expert opinion on therapeutic patentes, 27, 721, 10.1080/13543776.2017.1281248

WHO, 2019

WHO, 2019

Keyaerts, 2004, Inhibition of SARS-coronavirus infection in vitro by S-nitroso-N-acetylpenicillamine, a nitric oxide donor compound, Int J Infect Dis, 8, 223, 10.1016/j.ijid.2004.04.012

Lipsitch, 2003, Transmission dynamics and control of severe acute respiratory syndrome, Science, 300, 1966, 10.1126/science.1086616

WHO, 2005, Statement on the meeting of the International health regulations

Adams, 2012, Ratification vote on taxonomic proposals to the International Committee on Taxonomy of Viruses (2012), Arch Virol, 157, 1411, 10.1007/s00705-012-1299-6

King, 2012, Virus taxonomy, 486

Bermingham, 2012, Severe respiratory illness caused by a novel coronavirus, in a patient transferred to the United Kingdom from the Middle East, September 2012, Eurosurveillance, 17, 20290, 10.2807/ese.17.40.20290-en

Zaki, 2012, Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia, N Engl J Med, 367, 1814, 10.1056/NEJMoa1211721

Marra, 2003, The genome sequence of the SARS-associated coronavirus, Science, 300, 1399, 10.1126/science.1085953

Gorbalenya, 2006, Nidovirales: evolving the largest RNA virus genome, Virus Res, 117, 17, 10.1016/j.virusres.2006.01.017

Hu, 2015, Bat origin of human coronaviruses, Virology jornal, 12, 221, 10.1186/s12985-015-0422-1

Wu, 2020, Genome composition and divergence of the novel coronavirus (2019-nCoV) originating in China, Cell Host Microbe, 27, 325, 10.1016/j.chom.2020.02.001

Song, 2019, From SARS to MERS, thrusting coronaviruses into the spotlight, Viruses, 11, 59, 10.3390/v11010059

Bhardwaj, 2004, The severe acute respiratory syndrome coronavirus Nsp15 protein is an endoribonuclease that prefers manganese as a cofactor, J Virol, 78, 12218, 10.1128/JVI.78.22.12218-12224.2004

Decroly, 2011, Crystal structure and functional analysis of the SARS-coronavirus RNA cap 2′-O-methyltransferase nsp10/nsp16 complex, PLoS Pathog, 7, e1002059, 10.1371/journal.ppat.1002059

Sevajol, 2014, Insights into RNA synthesis, capping, and proofreading mechanisms of SARS-coronavirus, Virus Res, 194, 90, 10.1016/j.virusres.2014.10.008

Lehmann, 2015, Discovery of an essential nucleotidylating activity associated with a newly delineated conserved domain in the RNA polymerase-containing protein of all nidoviruses, Nucleic Acids Res, 43, 8416, 10.1093/nar/gkv838

Cui, 2019, Origin and evolution of pathogenic coronaviruses, Nat Rev Microbiol, 17, 181, 10.1038/s41579-018-0118-9

Stadler, 2005, SARS: understanding the virus and development of rational therapy, Curr Mol Med, 5, 677, 10.2174/156652405774641124

Li, 2017, Mouse-adapted MERS coronavirus causes lethal lung disease in human DPP4 knockin mice, Proc Natl Acad Sci, 114, E3119, 10.1073/pnas.1619109114

Zhu, 2018, Predicting the receptor-binding domain usage of the coronavirus based on kmer frequency on spike protein, Infect Genet Evol, 61, 183, 10.1016/j.meegid.2018.03.028

Wu, 2020, A new coronavirus associated with human respiratory disease in China, Nature, 579, 265, 10.1038/s41586-020-2008-3

Ge, 2013, Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor, Nature, 503, 535, 10.1038/nature12711

Peng, 2020, Discovery of a novel coronavirus associated with the recent pneumonia outbreak in humans and its potential bat origin, BioRxiv, 01, 914952

Snijder, 2003, Unique and conserved features of genome and proteome of SARS-coronavirus, an early split-off from the coronavirus group 2 lineage, J Mol Biol, 331, 991, 10.1016/S0022-2836(03)00865-9

Peng, 2006, Long-lived memory T lymphocyte responses against SARS coronavirus nucleocapsid protein in SARS-recovered patients, Virology, 351, 466, 10.1016/j.virol.2006.03.036

Booth, 2003, Clinical features and short-term outcomes of 144 patients with SARS in the greater Toronto area, JAMA, 289, 2801, 10.1001/jama.289.21.JOC30885

Lee, 2003, A major outbreak of severe acute respiratory syndrome in Hong Kong, N Engl J Med, 348, 1986, 10.1056/NEJMoa030685

Panesar, 2003, Lymphopenia in SARS, Lancet, 361, 1985, 10.1016/S0140-6736(03)13557-X

Ajlan, 2014, Middle East respiratory syndrome coronavirus (MERS-CoV) infection: chest CT findings, Am J Roentgenol, 203, 782, 10.2214/AJR.14.13021

Arabi, 2015, Severe neurologic syndrome associated with Middle East respiratory syndrome corona virus (MERS-CoV), Infection, 43, 495, 10.1007/s15010-015-0720-y

Ko, 2016, Predictive factors for pneumonia development and progression to respiratory failure in MERS-CoV infected patients, J Infect, 73, 468, 10.1016/j.jinf.2016.08.005

Xu, 2020, Liver damage during highly pathogenic human coronavirus infections, Liver Int, 00, 1

Zhang, 2020, Clinical characteristics of 140 patients infected by SARS‐CoV‐2 in Wuhan, China, Allergy, 00, 1

Yu, 2003, Change of T lymphocyte and its activated subsets in SARS patients, Acta Academiae Medicinae Sinicae, 25, 542

Cai, 2004, Study on T cell subsets and their activated molecules from the convalescent SARS patients during two follow-up surveys, Chinese J Cell Mol Immunol, 20, 322

Josset, 2013, Cell host response to infection with novel human coronavirus EMC predicts potential antivirals and important differences with SARS coronavirus, MBio, 4, e00165, 10.1128/mBio.00165-13

Chu, 2014, Productive repliC.aTion of Middle East respiratory syndrome coronavirus in monocyte-derived dendritic cells modulates innate immune response, Virology, 454, 197, 10.1016/j.virol.2014.02.018

Ying, 2016, Discovery of T-cell infection and apoptosis by Middle East respiratory syndrome coronavirus, J Infect Dis, 213, 877, 10.1093/infdis/jiv381

Ishii, 2001, CD26-mediated signaling for T cell activation occurs in lipid rafts through its association with CD45RO, Proc Natl Acad Sci, 98, 12138, 10.1073/pnas.211439098

Manni, 2014, A tale of two cytokines: IL-17 and IL-22 in asthma and infection, Expert Rev Respir Med, 8, 25, 10.1586/17476348.2014.854167

Mahallawi, 2018, MERS-CoV infection in humans is associated with a pro-inflammatory Th1 and Th17 cytokine profile, Cytokine, 104, 8, 10.1016/j.cyto.2018.01.025

Jin, 2013, IL-17 cytokines in immunity and inflammation, Emerg Microbes Infect, 2, 1, 10.1038/emi.2013.58

Park, 2015, Kinetics of serologic responses to MERS coronavirus infection in humans, South Korea, Emerging Infect Dis, 21, 2186, 10.3201/eid2112.151421

Corman, 2016, Viral shedding and antibody response in 37 patients with Middle East respiratory syndrome coronavirus infection, Clin Infect Dis, 62, 477

Alshukairi, 2016, Antibody response and disease severity in healthcare worker MERS survivors, Emerging Infect Dis, 22, 1113, 10.3201/eid2206.160010

Liu, 2006, Two-year prospective study of the humoral immune response of patients with severe acute respiratory syndrome, J Infect Dis, 193, 792, 10.1086/500469

Tang, 2011, Lack of peripheral memory B cell responses in recovered patients with severe acute respiratory syndrome: a six-year follow-up study, J Immunol, 186, 7264, 10.4049/jimmunol.0903490

Wang, 2004, T-cell epitopes in severe acute respiratory syndrome (SARS) coronavirus spike protein elicit a specific T-cell immune response in patients who recover from SARS, J Virol, 78, 5612, 10.1128/JVI.78.11.5612-5618.2004

Xu, 2004, Immunological responses against SARS-coronavirus infection in humans, Cell Mol Immunol, 1, 119

Yang, 2006, Long-lived effector/central memory T-cell responses to severe acute respiratory syndrome coronavirus (SARS-CoV) S antigen in recovered SARS patients, Clin Immunol, 120, 171, 10.1016/j.clim.2006.05.002

Libraty, 2007, Human CD4+ memory T-lymphocyte responses to SARS coronavirus infection, Virology, 368, 317, 10.1016/j.virol.2007.07.015

Chen, 2005, Response of memory CD8+ T cells to severe acute respiratory syndrome (SARS) coronavirus in recovered SARS patients and healthy individuals, J Immunol, 175, 591, 10.4049/jimmunol.175.1.591

Openshaw, 2004, What does the peripheral blood tell you in SARS?, Clin Exp Immunol, 136, 11, 10.1111/j.1365-2249.2004.02448.x

Yang, 2007, Persistent memory CD4+ and CD8+ T-cell responses in recovered severe acute respiratory syndrome (SARS) patients to SARS coronavirus M antigen, J Gen Virol, 88, 2740, 10.1099/vir.0.82839-0

Martin, 2008, A SARS DNA vaccine induces neutralizing antibody and cellular immune responses in healthy adults in a Phase I clinical trial, Vaccine, 26, 6338, 10.1016/j.vaccine.2008.09.026

Huang, 2020, Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China, Lancet, 395, 497, 10.1016/S0140-6736(20)30183-5

Li, 2016, Structure, function, and evolution of coronavirus spike proteins, Annu Rev Virol, 3, 237, 10.1146/annurev-virology-110615-042301

Hui, 2018, Middle East respiratory syndrome coronavirus: risk factors and determinants of primary, household, and nosocomial transmission, Lancet Infect Dis, 18, e217, 10.1016/S1473-3099(18)30127-0

European Centre for Disease Prevention and Control (ECDC), 2018

Kong, 2020, Chest imaging apperance of COVID-19 infection, Radiol Cardio Imag, 2, e200028

Santos, 2003, Ground-glass opacity in diffuse lung diseases: high-resolution computed tomography-pathology correlation, Radiol Bras, 36

Alserehi, 2016, Impact of Middle East Respiratory Syndrome coronavirus (MERS‐CoV) on pregnancy and perinatal outcome, BMC Infect Dis, 16, 105, 10.1186/s12879-016-1437-y

Assiri, 2016, Middle East Respiratory syndrome coronavirus infection during pregnancy: a report of 5 cases from Saudi Arabia, Clin Infect Dis, 63, 951, 10.1093/cid/ciw412

CDC, 2013, Update: severe respiratory illness associated with Middle East Respiratory Syndrome Coronavirus (MERS-CoV) worldwide, 2012-2013, MMWR Morb Mortal Wkly Rep, 62, 480

Chen, 2020, Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records, Lancet, 12

Cabral, 2002, Maternal serum level of C-reactive protein in gestations complicated by preeclampsia, Rev Bras Ginecol Obstet, 24

Hvilsom, 2002, C-reactive protein: a serological marker for preterm delivery?, Acta Obstet Gynecol Scand, 81, 424, 10.1034/j.1600-0412.2002.810509.x

Tjoa, 2003, Elevated C-reactive protein levels during first trimester of pregnancy are indicative of preeclampsia and intrauterine growth restriction, J Reprod Immunol, 59, 29, 10.1016/S0165-0378(02)00085-2

Robinson, 2012, Pregnancy and pregnancy-associated hormones alter immune responses and disease pathogenesis, Horm Behav, 62, 263, 10.1016/j.yhbeh.2012.02.023

Lee, 2005, The immediate effects of the severe acute respiratory syndrome (SARS) epidemic on childbirth in Taiwan, BMC Public Health, 5, 10.1186/1471-2458-5-30

Lee, 2006, Psychological responses of pregnant women to an infectious outbreak: a case-control study of the 2003 SARS outbreak in Hong Kong, J Psychosom Res, 61, 707, 10.1016/j.jpsychores.2006.08.005

Lam, 2004, A case-controlled study comparing clinical course and outcomes of pregnant and non-pregnant women with severe acute respiratory syndrome, Bjog Int J Obstet Gynaecol, 111, 771, 10.1111/j.1471-0528.2004.00199.x

Zhang, 2003, Clinical analysis of pregnancy in second and third trimesters complicated severe acute respiratory syndrome, Zhonghua Fu Chan Ke Za Zhi, 38, 516

Stockman, 2004, SARS during pregnancy, United States, Emerg Infect Dis., 10, 1689, 10.3201/eid1009.040244

Park, 2016, Emergency cesarean section in an epidemic of the middle east respiratory syndrome: a case report, Korean J Anesthesiol, 69, 287, 10.4097/kjae.2016.69.3.287

Racicot, 2014, Understanding the complexity of the immune system during pregnancy, Am J Reprod Immunol., 72, 107, 10.1111/aji.12289

Jeong, 2017, MERS-CoV Infection in a pregnant woman in Korea, J Korean Med Sci, 32, 1717, 10.3346/jkms.2017.32.10.1717

Racicot, 2017, Risks associated with viral infections during pregnancy, J Clin Invest, 127, 1591, 10.1172/JCI87490

Alfaraj, 2019, Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection during pregnancy: report of two cases & review of the literature, J Microbiol Immunol Infect, 52, 501, 10.1016/j.jmii.2018.04.005

Favre, 2020, 2019-nCoV epidemic: what about pregnancies?, Lancet, 395, 10224, 10.1016/S0140-6736(20)30311-1

Zhu, 2020, Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia, Transl Pediatr, 9, 51, 10.21037/tp.2020.02.06

Schwartz, 2020, An analysis of 38 pregnant women with COVID-19, their newborn infants, and maternal-fetal transmission of SARS-CoV-2: maternal coronavirus infections and pregnancy outcomes, Arch Pathol Lab Med, 10.5858/arpa.2020-0901-SA

Wang, 2020, A case report of neonatal COVID-19 infection in China, Clin Infect Dis

Fan, 2020, Perinatal Transmission of COVID-19 Associated SARS-CoV-2: Should We Worry?, Clin Infect Dis, 226

Shek, 2003, Infants born to mothers with severe acute respiratory syndrome, Pediatrics, 112, 10.1542/peds.112.4.e254

Lu, 2020, Coronavirus disease (COVID‐19) and neonate: what neonatologist need to know, J Med Virol, 92, 564, 10.1002/jmv.25740

Mustafa, 2018, Current treatment options and the role of peptides as potential therapeutic components for Middle East Respiratory Syndrome (MERS): a review, J Infect Public Health, 11, 9, 10.1016/j.jiph.2017.08.009

Yao, 2020, A systematic review of lopinavir therapy for SARS coronavirus and MERS coronavirus–A possible reference for coronavirus Disease‐19 treatment option, J Med Virol, 92, 556, 10.1002/jmv.25729

Arabi, 2019, Ribavirin and interferon therapy for critically ill patients with middle east respiratory syndrome: a multicenter observational study, Clin Infect Dis, 70, 1837, 10.1093/cid/ciz544

Momattin, 2019, A Systematic Review of therapeutic agents for the treatment of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV), Travel Med Infect Dis, 30, 9, 10.1016/j.tmaid.2019.06.012

Wit, 2020, Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection, Proc Natl Acad Sci, 117, 6771, 10.1073/pnas.1922083117

Mulangu, 2019, A randomized, controlled trial of Ebola virus disease therapeutics, N Engl J Med, 381, 2293, 10.1056/NEJMoa1910993

Kim, 2016, Extensive viable Middle East respiratory syndrome (MERS) coronavirus contamination in air and surrounding environment in MERS isolation wards, Rev Infect Dis, 63, 363, 10.1093/cid/ciw239

Arabi, 2020, Treatment of Middle East respiratory syndrome with a combination of lopinavir/ritonavir and interferon-β1b (MIRACLE trial): statistical analysis plan for a recursive two-stage group sequential randomized controlled trial, Trials, 21, 1, 10.1186/s13063-019-3846-x

Momattin, 2013, Therapeutic options for Middle East respiratory syndrome coronavirus (MERS-CoV)–possible lessons from a systematic review of SARS-CoV therapy, Int J Infect Dis, 17, e792, 10.1016/j.ijid.2013.07.002

Chang, 2016, Structure-based virtual screening and experimental validation of the discovery of inhibitors targeted towards the human coronavirus nucleocapsid protein, Mol Biosyst, 12, 59, 10.1039/C5MB00582E

Dayer, 2017, A Potent Drug against Coronavirus Infection: Insight from Molecular Docking Study, Arch Clin Infect Dis, 12, 10.5812/archcid.13823

Lin, 2020, Molecular Modeling Evaluation of the Binding Effect of Ritonavir, Lopinavir and Darunavir to Severe Acute Respiratory Syndrome Coronavirus 2 Proteases, bioRxiv, 01, 929695

Dieterich, DT. Method of treating anemia caused by ribavirin treatment of hepatitis C using erythropoietin alpha. U.S. Patent 2019; 10: 434-143.

Nyström, 2019, Ribavirin: pharmacology, multiple modes of action and possible future perspectives, Future Virol, 14, 153, 10.2217/fvl-2018-0166

Sinclair, 2017, The Ribavirin Pregnancy Registry: an interim analysis of potential teratogenicity at the mid-point of enrollment, Drug Saf, 40, 1205, 10.1007/s40264-017-0566-6

Merino, 2017, Hydroxychloroquine, a potentially lethal drug, Med Intensiva, 41, 257

Wilde, 2014, Screening of an FDA-approved compound library identifies four small-molecule inhibitors of Middle East respiratory syndrome coronavirus replication in cell culture, Antimicrob Agents Chemother, 58, 4875, 10.1128/AAC.03011-14

Cong, 2018, MERS-CoV pathogenesis and antiviral efficacy of licensed drugs in human monocyte-derived antigen-presenting cells, PLoS One, 13, 10.1371/journal.pone.0194868

Mo, 2016, A review of treatment modalities for Middle East respiratory syndrome, J Antimicrob Chemother, 71, 3340, 10.1093/jac/dkw338

Gautret, 2020, Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial, J Pre-proof., 20, 0924

2020

De Souza Oliveira, 2020, COVID-19: a pandemic that alert to the population, Inter Am J Med Health, 3, 1

Pauque, 1969, Retinal degeneration in two children following preventive antimalarial treatment of the mother during pregnancy, Bull Soc Ophtalmol Fr, 69, 466

Kaplan, 2016, Reproductive outcomes following hydroxychloroquine use for autoimmune diseases: a systematic review and metaanalysis, Br J Clin Pharmacol, 81, 835, 10.1111/bcp.12872

Kaplan, 2020, Use of hydroxychloroquine during pregnancy and breastfeeding: an update for the recent coronavirus pandemic (COVID-19), Motherisk Int J

Sperber, 2009, Systematic review of hydroxychloroquine use in pregnant patients with autoimmune diseases, Pediatr Rheumatol Online J, 7, 9, 10.1186/1546-0096-7-9

Al-Tawfiq, 2017, Update on therapeutic options for Middle East respiratory syndrome coronavirus (MERS-CoV), Expert Rev Anti Infect Ther, 15, 269, 10.1080/14787210.2017.1271712

Channappanavar, 2019, IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes, J Clin Invest, 129, 10.1172/JCI126363

Habib, 2019, Clinical outcomes among hospital patients with Middle East respiratory syndrome coronavirus (MERS-CoV) infection, BMC Infect Dis, 19, 1, 10.1186/s12879-019-4555-5

Lokugamage, 2020, SARS-CoV-2 sensitive to type I interferon pretreatment, bioRxiv, 03, 982264

Yazdani, 2012, A systematic review of the fetal safety of interferon alpha, Reprod Toxicol, 33, 265, 10.1016/j.reprotox.2011.11.003

Spera, 2016, Antiviral therapy for hepatitis C: Has anything changed for pregnant/lactating women?, World J Hepatol, 8, 557, 10.4254/wjh.v8.i12.557

Peck‐Radosavljevic, 2017, Thrombocytopenia in chronic liver disease, Liver Int, 37, 778, 10.1111/liv.13317

Balsat, 2018, Successful pregnancies in patients with BCR‐ABL‐positive leukemias treated with interferon‐alpha therapy during the tyrosine kinase inhibitors era, Eur J Haematol, 101, 774, 10.1111/ejh.13167

Da Silva, 2019, Portulaca elatior root contains a trehalose-binding lectin with antibacterial and antifungal activities, Int J Biol Macromol, 126, 291, 10.1016/j.ijbiomac.2018.12.188

Zhou, 2010, A single asparagine-linked glycosylation site of the Severe Acute Respiratory Syndrome coronavirus spike glycoprotein facilitates inhibition by mannose-binding lectin through multiple mechanisms, J Virology, 84, 8753, 10.1128/JVI.00554-10

Ip, 2005, Mannose-binding lectin in severe acute respiratory syndrome coronavirus infection, J Infect Dis, 191, 1697, 10.1086/429631

Zumla, 2016, Coronaviruses - drug discovery and therapeutic options, Nat Rev Drug Discov, 15, 327, 10.1038/nrd.2015.37

Haagmans, 2016, An orthopoxvirus-based vaccine reduces virus excretion after MERS-CoV infection in dromedary camels, Science, 351, 77, 10.1126/science.aad1283