Running-Induced Systemic Cathepsin B Secretion Is Associated with Memory Function

Abrous, 2015, Interaction between neurogenesis and hippocampal memory system: new vistas, Cold Spring Harb. Perspect. Biol., 7, a018952, 10.1101/cshperspect.a018952

Aggarwal, 2014, Cathepsin B: multiple roles in cancer, Proteomics Clin. Appl., 8, 427, 10.1002/prca.201300105

Agudelo, 2014, Skeletal muscle PGC-1α1 modulates kynurenine metabolism and mediates resilience to stress-induced depression, Cell, 159, 33, 10.1016/j.cell.2014.07.051

Banerjee, 2015, Increased levels and activity of cathepsins B and D in kainate-induced toxicity, Neuroscience, 284, 360, 10.1016/j.neuroscience.2014.10.003

Bednarski, 1998, Lysosomal dysfunction reduces brain-derived neurotrophic factor expression, Exp. Neurol., 150, 128, 10.1006/exnr.1997.6747

Bendiske, 2003, Lysosomal activation is a compensatory response against protein accumulation and associated synaptopathogenesis--an approach for slowing Alzheimer disease?, J. Neuropathol. Exp. Neurol., 62, 451, 10.1093/jnen/62.5.451

Cavallo-Medved, 2009, Live-cell imaging demonstrates extracellular matrix degradation in association with active cathepsin B in caveolae of endothelial cells during tube formation, Exp. Cell Res., 315, 1234, 10.1016/j.yexcr.2009.01.021

Chao, 2006, Neurotrophin signalling in health and disease, Clin. Sci., 110, 167, 10.1042/CS20050163

Czibere, 2011, Profiling trait anxiety: transcriptome analysis reveals cathepsin B (Ctsb) as a novel candidate gene for emotionality in mice, PLoS ONE, 6, e23604, 10.1371/journal.pone.0023604

Devi, 2004, Regional responses in antioxidant system to exercise training and dietary vitamin E in aging rat brain, Neurobiol. Aging, 25, 501, 10.1016/S0197-4580(03)00112-X

Duzel, 2016, Can physical exercise in old age improve memory and hippocampal function?, Brain, 139, 662, 10.1093/brain/awv407

Eriksson, 2013, Bidirectional regulation of emotional memory by 5-HT1B receptors involves hippocampal p11, Mol. Psychiatry, 18, 1096, 10.1038/mp.2012.130

Felbor, 2002, Neuronal loss and brain atrophy in mice lacking cathepsins B and L, Proc. Natl. Acad. Sci. USA, 99, 7883, 10.1073/pnas.112632299

Harris, 1990, The localized elevation of cathepsins B and L in rat gastrocnemius muscle following tenotomy, Biochem. Soc. Trans., 18, 1254, 10.1042/bst0181254

Hawley, 2014, Integrative biology of exercise, Cell, 159, 738, 10.1016/j.cell.2014.10.029

Hook, 2008, Inhibitors of cathepsin B improve memory and reduce beta-amyloid in transgenic Alzheimer disease mice expressing the wild-type, but not the Swedish mutant, beta-secretase site of the amyloid precursor protein, J. Biol. Chem., 283, 7745, 10.1074/jbc.M708362200

Katsimpardi, 2014, Vascular and neurogenic rejuvenation of the aging mouse brain by young systemic factors, Science, 344, 630, 10.1126/science.1251141

Kawauchi, 2015, Cellullar insights into cerebral cortical development: focusing on the locomotion mode of neuronal migration, Front. Cell. Neurosci., 9, 394, 10.3389/fncel.2015.00394

Klempin, 2013, Serotonin is required for exercise-induced adult hippocampal neurogenesis, J. Neurosci., 33, 8270, 10.1523/JNEUROSCI.5855-12.2013

Kobilo, 2011, Endurance factors improve hippocampal neurogenesis and spatial memory in mice, Learn. Mem., 18, 103, 10.1101/lm.2001611

Kobilo, 2014, AMPK agonist AICAR improves cognition and motor coordination in young and aged mice, Learn. Mem., 21, 119, 10.1101/lm.033332.113

Lemaire, 1997, Alternative splicing of the 5′ region of cathepsin B pre-messenger RNA in rheumatoid synovial tissue, Arthritis Rheum., 40, 1540, 10.1002/art.1780400824

Morel, 2007, The p11/S100A10 light chain of annexin A2 is dispensable for annexin A2 association to endosomes and functions in endosomal transport, PLoS ONE, 2, e1118, 10.1371/journal.pone.0001118

Mueller-Steiner, 2006, Antiamyloidogenic and neuroprotective functions of cathepsin B: implications for Alzheimer’s disease, Neuron, 51, 703, 10.1016/j.neuron.2006.07.027

Nowakowski, 1981, The site of origin and route and rate of migration of neurons to the hippocampal region of the rhesus monkey, J. Comp. Neurol., 196, 129, 10.1002/cne.901960110

Olson, 2015, Cysteine cathepsin proteases: regulators of cancer progression and therapeutic response, Nat. Rev. Cancer, 15, 712, 10.1038/nrc4027

Pedersen, 2008, Muscle as an endocrine organ: focus on muscle-derived interleukin-6, Physiol. Rev., 88, 1379, 10.1152/physrev.90100.2007

Radak, 2013, Oxygen consumption and usage during physical exercise: the balance between oxidative stress and ROS-dependent adaptive signaling, Antioxid. Redox Signal., 18, 1208, 10.1089/ars.2011.4498

Salminen, 1984, Lysosomal changes related to exercise injuries and training-induced protection in mouse skeletal muscle, Acta Physiol. Scand., 120, 15, 10.1111/j.1748-1716.1984.tb07367.x

Sartori, 2011, The antidepressive effect of the physical exercise correlates with increased levels of mature BDNF, and proBDNF proteolytic cleavage-related genes, p11 and tPA, Neuroscience, 180, 9, 10.1016/j.neuroscience.2011.02.055

Sooksawate, 2001, Effects of membrane cholesterol on the sensitivity of the GABA(A) receptor to GABA in acutely dissociated rat hippocampal neurones, Neuropharmacology, 40, 178, 10.1016/S0028-3908(00)00159-3

Svenningsson, 2013, p11 and its role in depression and therapeutic responses to antidepressants, Nat. Rev. Neurosci., 14, 673, 10.1038/nrn3564

Turk, 2012, Cysteine cathepsins: from structure, function and regulation to new frontiers, Biochim. Biophys. Acta, 1824, 68, 10.1016/j.bbapap.2011.10.002

Vargha-Khadem, 1997, Differential effects of early hippocampal pathology on episodic and semantic memory, Science, 277, 376, 10.1126/science.277.5324.376

Voss, 2013, Bridging animal and human models of exercise-induced brain plasticity, Trends Cogn. Sci., 17, 525, 10.1016/j.tics.2013.08.001

Wang, 2012, Effect of shRNA mediated down-regulation of Annexin A2 on biological behavior of human lung adenocarcinoma cells A549. Pathology oncology research, Pathol. Oncol. Res., 18, 183, 10.1007/s12253-011-9427-2

Westerink, 2008, The PC12 cell as model for neurosecretion, Acta Physiol. (Oxf.), 192, 273, 10.1111/j.1748-1716.2007.01805.x

Wong, 2013, Cathepsin B is a novel gender-dependent determinant of cholesterol absorption from the intestine, J. Lipid Res., 54, 816, 10.1194/jlr.M034579

Wrann, 2015, FNDC5/Irisin – Their role in the nervous system and as a mediator for beneficial effects of exercise on the brain, Br. Plast., 1, 55, 10.3233/BPL-150019

Yakovlev, 2015, Possible role of proteases in preconditioning of brain cells to pathological conditions, Biochemistry (Mosc.), 80, 163, 10.1134/S0006297915020030

Yoshida, 2002, Primate neurons show different vulnerability to transient ischemia and response to cathepsin inhibition, Acta Neuropathol., 104, 267, 10.1007/s00401-002-0554-4