Roles of p53, c-Myc, Bcl-2, Bax and caspases in glutamate-induced neuronal apoptosis and the possible neuroprotective mechanism of basic fibroblast growth factor

Adams, 1998, The Bcl-2 protein family: arbiters of cell survival?, Science, 281, 322, 10.1126/science.281.5381.1322 Ankarcrona, 1998, Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function, Neuron, 15, 961, 10.1016/0896-6273(95)90186-8 Antonella, 1992, Flow cytometric detection of the mitochondrial Bcl-2 protein in normal and neoplastic human lymphoid cells, Cytometry, 13, 502, 10.1002/cyto.990130509 Asahi, 1997, Expression of Interleukin-1 β converting enzyme gene family in the rat brain following permanent occlusion of the middle cerebral artery, J. Cereb. Blood Flow Metab., 17, 11, 10.1097/00004647-199701000-00003 Banasiak, 1998, Hypoxia-induced apoptosis: effect of hypoxic severity and roles of p53 in neuronal cell death, Brain Res., 797, 295, 10.1016/S0006-8993(98)00286-8 Benini, 1998, p53 expression in human carcinomas: could flow cytometry be an alternative to immunhistochemistry?, J. Histochem. Cytochem., 46, 41, 10.1177/002215549804600106 Bethel, 1997, Intravenous basic fibroblast growth factor decrease brain injury resulting from focal ischemia in cats, Stroke, 28, 609, 10.1161/01.STR.28.3.609 Bonfoco, 1998, Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures, Proc. Natl. Acad. Sci. U.S.A., 92, 7162, 10.1073/pnas.92.16.7162 Choi, 1992, Excitotoxic cell death, J. Neurobiol., 23, 1261, 10.1002/neu.480230915 Digiuseppe, 1996, Multiparameter flow-cytometric analysis of bcl-2 and Fas expression in normal and neoplastic hematopoiesis, Am. J. Clin. Pathol., 106, 345, 10.1093/ajcp/106.3.345 Du, 1997, Activation of a caspase-3-related cysteine protease is required for glutamate-mediated apoptosis of cultured cerebellar granule neurons, Proc. Natl. Acad. Sci. U.S.A., 94, 11657, 10.1073/pnas.94.21.11657 Eizenberg, 1998, p53 play a regulatory role in differentiation and apoptosis of central nervous cystem-associated cells, Mol. Cell Biol., 16, 5178, 10.1128/MCB.16.9.5178 Evan, 1998, A matter of life and cell death, Science, 281, 317, 10.1126/science.281.5381.1317 German, 1998, Apoptosis in neuronal cells: role of caspases, Neuroreport, 9, R49, 10.1097/00001756-199807130-00001 Hughes, 1997, A role for the tumor suppressor gene p53 in regulating neuronal apoptosis, Neuroreport, 8, V Knudson, 1997, Bcl-2 and Bax function independently to regulate cell death, Nat. Genet., 16, 358, 10.1038/ng0897-358 Landberg, 1992, Flow cytometric analysis of proliferation associated nuclear antigens using washless staining of unfixed cells, Cytometry, 13, 230, 10.1002/cyto.990130304 Lipton, 1994, Excitatory amino acids as a final common pathway for neurologic disorders, N. Engl. J. Med., 330, 613, 10.1056/NEJM199403033300907 Louis, 1993, Survival promoting and protein kinase-regulating roles of basic FGF for hippocampal neurons exposed to phorbol ester, glutamate and ischemia-like conditions, Eur. J. Neurosci., 5, 1610, 10.1111/j.1460-9568.1993.tb00230.x Martin, 1998, Neurodegeneration in excitotoxicity, global cerebral ischemia, and target deprivation: a perspective on the contribution of apoptosis and necrosis, Brain Res. Bull., 46, 281, 10.1016/S0361-9230(98)00024-0 Mattson, 1989, Fibroblast growth factor and glutamate: opposing roles in the generation and degeneration of hippocampal neuroarchitecture, J. Neurosci., 9, 3728, 10.1523/JNEUROSCI.09-11-03728.1989 Merry, 1997, Bcl-2 gene family in the nervous system, Annu. Rev. Neurosci., 20, 245, 10.1146/annurev.neuro.20.1.245 Miyashita, 1995, Tumor suppressor p53 is a direct transcriptional activator of the human bax gene, Cell, 80, 293, 10.1016/0092-8674(95)90412-3 Montal, 1998, Mitochondria, glutamate neurotoxicity and the death cascade, Biochim. Biophys. Acta, 1366, 113, 10.1016/S0005-2728(98)00124-8 Nakata, 1993, Protective effects of basic fibroblast growth factor against hippocampal neuronal damage following cerebral ischemia in the gerbil, Brain Res., 605, 354, 10.1016/0006-8993(93)91766-L Nath, 1998, Evidence for activation of caspase-3-like protease in excitotoxic and hypoxia/hypoglycemia-injured neurons, J. Neurochem., 71, 186, 10.1046/j.1471-4159.1998.71010186.x Ohgoh, 1998, Apoptotic cell death of cultured cerebral cortical neurons induced by withdrawal of astroglial trophic support, Exp. Neurol., 149, 51, 10.1006/exnr.1997.6719 Oltvai, 1993, Bcl-2 heterodimerizes in vivo with a conserved homologue, Bax, that accelerates programmed cell death, Cell, 74, 609, 10.1016/0092-8674(93)90509-O Peter, 1997, Advances in apoptosis research, Proc. Natl. Acad. Sci. U.S.A., 94, 12736, 10.1073/pnas.94.24.12736 Pettmann, 1998, Neuronal cell death, Neuron, 20, 633, 10.1016/S0896-6273(00)81004-1 Reed, 1997, Double identity for proteins of the Bcl-2 family, Nature, 387, 773, 10.1038/42867 Reed, 1998, Bcl-2 family proteins and mitochondria, Biochim. Biophys. Acta, 1366, 127, 10.1016/S0005-2728(98)00108-X Ren, 1997, Time window of infarct reduction by intravenous basic fibroblast growth factor in focal cerebral ischemia, Eur. J. Pharmacol., 327, 11, 10.1016/S0014-2999(97)89672-0 Rubin, 1997, Neuronal cell death: when, why and how, Br. Med. Bull., 53, 617, 10.1093/oxfordjournals.bmb.a011634 Sane, 1998, Distinct steps in DNA fragmentation pathway during camptothecin-induced apoptosis involved Caspase-, Benzyloxycarbonyl- and N-Tosyl-L-Pheylalanylchloromethyl Ketone-sensitive activities, Cancer Res., 58, 3066 Savitz, 1998, Apoptosis in neurological diseases, Neurosurgery, 42, 555, 10.1097/00006123-199803000-00026 Sedlak, 1995, Multiple Bcl-2 family members demonstrate selective dimerizations with Bax, Proc. Natl. Acad. Sci. U.S.A., 92, 7834, 10.1073/pnas.92.17.7834 Sei, 1998, Quinolinic acid protects rat cerebellar granule cells from glutamate-induced apoptosis, Neurosci. Lett., 241, 180, 10.1016/S0304-3940(97)00980-4 Selvakumaran, 1994, Immediate early up-regulation of bax expression by p53 but not TGF-β, a paradigm for distinct apoptotic pathways, Oncogene, 9, 1791 Staton, 1997, The dietary excitotoxins β-N-methylamino-L-alanine and β-N-oxalylamino-L-alanine induce necrotic- and apoptotic-like death of rat cerebellar granule cells, J. Neurochem., 69, 1508, 10.1046/j.1471-4159.1997.69041508.x Staunton, 1998, Apoptosis: basic concepts and potential significance in human cancer, Arch. Pathol. Lab. Med., 122, 310 Tamatani, 1998, Roles of Bcl-2 and caspases in hypoxia-induced neuronal cell death: a possible neuroprotective mechanism of peptide growth factors, Mol. Brain Res., 58, 27, 10.1016/S0169-328X(98)00095-3 Tenneti, 1998, Roles of caspases in N-methyl-D-Aspartate-induced apoptosis in cerebrocortical neurons, J. Neurochem., 71, 946, 10.1046/j.1471-4159.1998.71030946.x Wood, 1998, N-methyl-D-Aspartate receptor desensitization is neuroprotective by inhibiting glutamate-induced apoptotic-like death, J. Neurochem., 70, 677, 10.1046/j.1471-4159.1998.70020677.x Yang, 1996, Molecular thanatopsis: a discourse on the Bcl-2 family and cell death, Blood, 88, 386, 10.1182/blood.V88.2.386.bloodjournal882386 Zorumiski, 1993, Excitotoxic neuronal damage and neuropsychiatric disorders, Pharmacol. Ther., 59, 145, 10.1016/0163-7258(93)90043-D