Role of tumor necrosis factor α (TNFα) in the onset of fructose-induced nonalcoholic fatty liver disease in mice

Lazo, 2008, The epidemiology of nonalcoholic fatty liver disease: a global perspective, Semin Liver Dis, 28, 339, 10.1055/s-0028-1091978 Bedogni, 2005, Prevalence of and risk factors for nonalcoholic fatty liver disease: the Dionysos nutrition and liver study, Hepatology, 42, 44, 10.1002/hep.20734 Yang, 2005, Attenuated hepatic inflammation and fibrosis in angiotensin type 1a receptor deficient mice, J Hepatol, 43, 317, 10.1016/j.jhep.2005.02.034 Adams, 2005, The natural history of nonalcoholic fatty liver disease: a population-based cohort study, Gastroenterology, 129, 113, 10.1053/j.gastro.2005.04.014 Spruss, 2009, Dietary fructose and intestinal barrier: potential risk factor in the pathogenesis of nonalcoholic fatty liver disease, J Nutr Biochem, 20, 657, 10.1016/j.jnutbio.2009.05.006 Armutcu, 2005, Thymosin alpha 1 attenuates lipid peroxidation and improves fructose-induced steatohepatitis in rats, Clin Biochem, 38, 540, 10.1016/j.clinbiochem.2005.01.013 Bergheim, 2008, Antibiotics protect against fructose-induced hepatic lipid accumulation in mice: role of endotoxin, J Hepatol, 48, 983, 10.1016/j.jhep.2008.01.035 Jurgens, 2005, Consuming fructose-sweetened beverages increases body adiposity in mice, Obes Res, 13, 1146, 10.1038/oby.2005.136 Faeh, 2005, Effect of fructose overfeeding and fish oil administration on hepatic de novo lipogenesis and insulin sensitivity in healthy men, Diabetes, 54, 1907, 10.2337/diabetes.54.7.1907 Lewis, 2004, Hepatic lipase mRNA, protein, and plasma enzyme activity is increased in the insulin-resistant, fructose-fed Syrian golden hamster and is partially normalized by the insulin sensitizer rosiglitazone, Diabetes, 53, 2893, 10.2337/diabetes.53.11.2893 Spruss, 2009, Toll-like receptor 4 is involved in the development of fructose-induced hepatic steatosis in mice, Hepatology, 50, 1094, 10.1002/hep.23122 Tomita, 2006, Tumour necrosis factor alpha signalling through activation of Kupffer cells plays an essential role in liver fibrosis of non-alcoholic steatohepatitis in mice, Gut, 55, 415, 10.1136/gut.2005.071118 Ma, 2008, Probiotics improve high fat diet-induced hepatic steatosis and insulin resistance by increasing hepatic NKT cells, J Hepatol, 49, 821, 10.1016/j.jhep.2008.05.025 Li, 2003, Probiotics and antibodies to TNF inhibit inflammatory activity and improve nonalcoholic fatty liver disease, Hepatology, 37, 343, 10.1053/jhep.2003.50048 Memon, 2001, TNF-alpha is not the cause of fatty liver disease in obese diabetic mice, Nat Med, 7, 2, 10.1038/83316 Lalor, 2007, The role of cytokines and chemokines in the development of steatohepatitis, Semin Liver Dis, 27, 173, 10.1055/s-2007-979470 Latta, 2007, ATP-depleting carbohydrates prevent tumor necrosis factor receptor 1-dependent apoptotic and necrotic liver injury in mice, J Pharmacol Exp Ther, 321, 875, 10.1124/jpet.107.119958 Nair, 2003, Hepatic ATP reserve and efficiency of replenishing: comparison between obese and nonobese normal individuals, Am J Gastroenterol, 98, 466 Cortez-Pinto, 1999, Alterations in liver ATP homeostasis in human nonalcoholic steatohepatitis: a pilot study, JAMA, 282, 1659, 10.1001/jama.282.17.1659 Robbez, 2008, Long-chain [n-3] polyunsaturated fatty acids prevent metabolic and vascular disorders in fructose-fed rats, J Nutr, 138, 1915, 10.1093/jn/138.10.1915 Kroder, 1996, Tumor necrosis factor-alpha- and hyperglycemia-induced insulin resistance. Evidence for different mechanisms and different effects on insulin signaling, J Clin Invest, 97, 1471, 10.1172/JCI118569 Popa, 2007, The role of TNF-alpha in chronic inflammatory conditions, intermediary metabolism, and cardiovascular risk, J Lipid Res, 48, 751, 10.1194/jlr.R600021-JLR200 Blakely, 1981, Long-term effects of moderate fructose feeding on glucose tolerance parameters in rats, J Nutr, 111, 307, 10.1093/jn/111.2.307 Thuy, 2008, Nonalcoholic fatty liver disease in humans is associated with increased plasma endotoxin and plasminogen activator inhibitor 1 concentrations and with fructose intake, J Nutr, 138, 1452, 10.1093/jn/138.8.1452 Alessi, 2003, Plasma PAI-1 levels are more strongly related to liver steatosis than to adipose tissue accumulation, Arterioscler Thromb Vasc Biol, 23, 1262, 10.1161/01.ATV.0000077401.36885.BB Zelber-Sagi, 2007, Long term nutritional intake and the risk for non-alcoholic fatty liver disease [NAFLD]: a population based study, J Hepatol, 47, 711, 10.1016/j.jhep.2007.06.020 Bode, 2003, Effect of alcohol consumption on the gut, Best Pract Res Clin Gastroenterol, 17, 575, 10.1016/S1521-6918(03)00034-9 Rivera, 1998, Role of endotoxin in the hypermetabolic state after acute ethanol exposure, Am J Physiol, 275, G1252 Yin, 2001, Alcohol-induced free radicals in mice: direct toxicants or signaling molecules?, Hepatology, 34, 935, 10.1053/jhep.2001.28888 Bergheim, 2006, Metformin prevents alcohol-induced liver injury in the mouse: critical role of plasminogen activator inhibitor-1, Gastroenterology, 130, 2099, 10.1053/j.gastro.2006.03.020 Ruiz, 2007, Lipopolysaccharide-binding protein plasma levels and liver TNF-alpha gene expression in obese patients: evidence for the potential role of endotoxin in the pathogenesis of non-alcoholic steatohepatitis, Obes Surg, 17, 1374, 10.1007/s11695-007-9243-7 Lin, 2000, Metformin reverses fatty liver disease in obese, leptin-deficient mice, Nat Med, 6, 998, 10.1038/79697 Grove, 1997, Association of a tumor necrosis factor promoter polymorphism with susceptibility to alcoholic steatohepatitis, Hepatology, 26, 143, 10.1002/hep.510260119 Valenti, 2002, Tumor necrosis factor alpha promoter polymorphisms and insulin resistance in nonalcoholic fatty liver disease, Gastroenterology, 122, 274, 10.1053/gast.2002.31065 Malaguarnera, 2009, Molecular mechanisms involved in NAFLD progression, J Mol Med, 87, 679, 10.1007/s00109-009-0464-1 Yan, 2007, Nuclear corepressor is required for inhibition of phosphoenolpyruvate carboxykinase expression by tumor necrosis factor-alpha, Mol Endocrinol, 21, 1630, 10.1210/me.2007-0072 Shimano, 2007, SREBP-1c and TFE3, energy transcription factors that regulate hepatic insulin signaling, J Mol Med, 85, 437, 10.1007/s00109-007-0158-5 Ma, 2004, Prevention of obesity and insulin resistance in mice lacking plasminogen activator inhibitor 1, Diabetes, 53, 336, 10.2337/diabetes.53.2.336