Role of the P2X7 receptor in the pathogenesis of type 2 diabetes and its microvascular complications
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Di Virgilio, 2018, Modulation of innate and adaptive immunity by P2X ion channels, Curr Opin Immunol, 52, 51, 10.1016/j.coi.2018.03.026
Adinolfi, 2018, The P2X7 receptor: a main player in inflammation, Biochem Pharmacol, 151, 234, 10.1016/j.bcp.2017.12.021
Burnstock, 2018, The potential of P2X7 receptors as a therapeutic target, including inflammation and tumour progression, Purinergic Signal, 14, 1, 10.1007/s11302-017-9593-0
Tozzi, 2018, The P2X7 receptor and pannexin-1 are involved in glucose-induced autocrine regulation in β-cells, Sci Rep, 8, 10.1038/s41598-018-27281-9
Uresti-Rivera, 2018, The presence of the 1068 G>A variant of P2X7 receptors is associated to an increase in IL-1Ra levels, insulin secretion and pancreatic β-cell function but not with glycemic control in type 2 diabetes patients, Gene, 652, 1, 10.1016/j.gene.2018.01.084
Portillo, 2017, CD40 in retinal Müller cells induces P2X7-dependent cytokine expression in macrophages/microglia in diabetic mice and development of early experimental diabetic retinopathy, Diabetes, 66, 483, 10.2337/db16-0051
Stachon, 2017, P2X(7) deficiency blocks lesional inflammasome activity and ameliorates atherosclerosis in mice, Circulation, 135, 2524, 10.1161/CIRCULATIONAHA.117.027400
Giacovazzo, 2018, Loss of P2X7 receptor function dampens whole body energy expenditure and fatty acid oxidation, Purinergic Signal, 14, 299, 10.1007/s11302-018-9610-y
Solini, 2013, The purinergic 2X7 receptor participates in renal inflammation and injury induced by high-fat diet: possible role of NLRP3 inflammasome activation, J Pathol, 231, 342, 10.1002/path.4237
Blasetti Fantauzzi, 2017, Deficiency of the purinergic receptor 2X(7) attenuates nonalcoholic steatohepatitis induced by high-fat diet: possible role of the NLRP3 inflammasome, Oxid Med Cell Longev, 2017, 10.1155/2017/8962458
Novak, 2018, P2X receptor-ion channels in the inflammatory response in adipose tissue and pancreas-potential triggers in onset of type 2 diabetes?, Curr Opin Immunol, 52, 1, 10.1016/j.coi.2018.02.002
Glas, 2009, Purinergic P2X(7) receptors regulate secretion of interleukin-1 receptor antagonist and beta cell function and survival, Diabetologia, 52, 1579, 10.1007/s00125-009-1349-0
Todd, 2015, Variation in glucose homeostasis traits associated with P2RX7 polymorphisms in mice and humans, J Clin Endocrinol Metab, 100, E688, 10.1210/jc.2014-4160
Tezza, 2018, Islet-derived eATP fuels autoreactive CD8(+) T cells and facilitates the onset of type 1 diabetes, Diabetes, 67, 2038, 10.2337/db17-1227
Madec, 2011, Adipocyte P2X7 receptors expression: a role in modulating inflammatory response in subjects with metabolic syndrome?, Atherosclerosis, 219, 552, 10.1016/j.atherosclerosis.2011.09.012
Pandolfi, 2015, Purinergic signaling modulates human visceral adipose inflammatory responses: implications in metabolically unhealthy obesity, J Leukoc Biol, 97, 941, 10.1189/jlb.3A1214-626R
Lee, 1997, Membrane responses to extracellular ATP in rat isolated white adipocytes, Pflugers Arch, 434, 422, 10.1007/s004240050416
Beaucage, 2014, Loss of P2X7 nucleotide receptor function leads to abnormal fat distribution in mice, Purinergic Signal, 10, 291, 10.1007/s11302-013-9388-x
Arguin, 2017, The loss of P2X7 receptor expression leads to increase intestinal glucose transit and hepatic steatosis, Sci Rep, 7, 10.1038/s41598-017-13300-8
Perruzza, 2017, T follicular helper cells promote a beneficial gut ecosystem for host metabolic homeostasis by sensing microbiota-derived extracellular ATP, Cell Rep, 18, 2566, 10.1016/j.celrep.2017.02.061
Wu, 2017, Skeletal muscle inflammation and insulin resistance in obesity, J Clin Invest, 127, 43, 10.1172/JCI88880
Cea, 2013, De novo expression of connexin hemichannels in denervated fast skeletal muscles leads to atrophy, Proc Natl Acad Sci U S A, 110, 16229, 10.1073/pnas.1312331110
Cea, 2016, Fast skeletal myofibers of mdx mouse, model of Duchenne muscular dystrophy, express connexin hemichannels that lead to apoptosis, Cell Mol Life Sci, 73, 2583, 10.1007/s00018-016-2132-2
Young, 2015, A novel mechanism of autophagic cell death in dystrophic muscle regulated by P2RX7 receptor large-pore formation and HSP90, Autophagy, 11, 113, 10.4161/15548627.2014.994402
Sinadinos, 2015, P2RX7 purinoceptor: a therapeutic target for ameliorating the symptoms of Duchenne muscular dystrophy, PLoS Med, 12, 10.1371/journal.pmed.1001888
Chiang, 2011, Obesity, diabetes mellitus, and liver fibrosis, Am J Physiol Gastrointest Liver Physiol, 300, G697, 10.1152/ajpgi.00426.2010
Chatterjee, 2015, P2X7 receptor as a key player in oxidative stress-driven cell fate in nonalcoholic steatohepatitis, Oxid Med Cell Longev, 2015, 10.1155/2015/172493
Das, 2013, Purinergic receptor X7 is a key modulator of metabolic oxidative stress-mediated autophagy and inflammation in experimental nonalcoholic steatohepatitis, Am J Physiol Gastrointest Liver Physiol, 305, G950, 10.1152/ajpgi.00235.2013
Toki, 2015, Extracellular ATP induces P2X7 receptor activation in mouse Kupffer cells, leading to release of IL-1beta, HMGB1, and PGE2, decreased MHC class I expression and necrotic cell death, Biochem Biophys Res Commun, 458, 771, 10.1016/j.bbrc.2015.02.011
Chandrashekaran, 2016, Purinergic receptor X7 mediates leptin induced GLUT4 function in stellate cells in nonalcoholic steatohepatitis, Biochem Biophys Acta, 1862, 32
Jiang, 2017, Potentiation of hepatic stellate cell activation by extracellular ATP is dependent on P2X7R-mediated NLRP3 inflammasome activation, Pharmacol Res, 117, 82, 10.1016/j.phrs.2016.11.040
Menzies, 2017, Hyperglycemia-induced renal P2X7 receptor activation enhances diabetes-related injury, EBioMedicine, 19, 73, 10.1016/j.ebiom.2017.04.011
Vonend, 2004, Glomerular expression of the ATP-sensitive P2X receptor in diabetic and hypertensive rat models, Kidney Int, 66, 157, 10.1111/j.1523-1755.2004.00717.x
Rodrigues, 2014, P2X(7) receptor in the kidneys of diabetic rats submitted to aerobic training or to N-acetylcysteine supplementation [corrected], PLoS One, 9, 10.1371/journal.pone.0097452
Rodrigues, 2018, P2X(7) receptor and klotho expressions in diabetic nephropathy progression, Purinergic Signal, 14, 167, 10.1007/s11302-018-9602-y
Thomas, 2009, Nonalbuminuric renal impairment in type 2 diabetic patients and in the general population (national evaluation of the frequency of renal impairment cO-existing with NIDDM [NEFRON] 11), Diabetes Care, 32, 1497, 10.2337/dc08-2186
Ninomiya, 2009, Albuminuria and kidney function independently predict cardiovascular and renal outcomes in diabetes, J Am Soc Nephrol, 20, 1813, 10.1681/ASN.2008121270
Penno, 2011, Clinical significance of nonalbuminuric renal impairment in type 2 diabetes, J Hypertens, 29, 1802, 10.1097/HJH.0b013e3283495cd6
Romagnani, 2013, Renal progenitors in non-diabetic and diabetic nephropathies, Trends Endocrinol Metab, 24, 13, 10.1016/j.tem.2012.09.002
Gonçalves, 2006, The role of purinergic P2X7 receptors in the inflammation and fibrosis of unilateral ureteral obstruction in mice, Kidney Int, 70, 1599, 10.1038/sj.ki.5001804
Yan, 2015, P2X7 receptor inhibition protects against ischemic acute kidney injury in mice, Am J Physiol Cell Physiol, 308, C463, 10.1152/ajpcell.00245.2014
Guan, 2007, P2X receptors as regulators of the renal microvasculature, Trends Pharmacol Sci, 28, 646, 10.1016/j.tips.2007.09.010
Kishore, 2005, Expression of NTPDase1 and NTPDase2 in murine kidney: relevance to regulation of P2 receptor signaling, Am J Physiol Renal Physiol, 288, F1032, 10.1152/ajprenal.00108.2004
Solini, 2015, The dark side of extracellular ATP in kidney diseases, J Am Soc Nephrol, 26, 1007, 10.1681/ASN.2014070721
Ji, 2012, P2X7 receptor antagonism attenuates the hypertension and renal injury in Dahl salt-sensitive rats, Hypertens Res, 35, 173, 10.1038/hr.2011.153
Menzies, 2015, Inhibition of the purinergic P2X7 receptor improves renal perfusion in angiotensin-II-infused rats, Kidney Int, 88, 1079, 10.1038/ki.2015.182
Franco, 2017, Physiopathological implications of P2X(1) and P2X(7) receptors in regulation of glomerular hemodynamics in angiotensin II-induced hypertension, Am J Physiol Renal Physiol, 313, F9, 10.1152/ajprenal.00663.2016
Chen, 2013, ATP-P2X4 signaling mediates NLRP3 inflammasome activation: a novel pathway of diabetic nephropathy, Int J Biochem Cell Biol, 45, 932, 10.1016/j.biocel.2013.02.009
Platania, 2017, P2X7 receptor antagonism: implications in diabetic retinopathy, Biochem Pharmacol, 138, 130, 10.1016/j.bcp.2017.05.001
Sugiyama, 2014, Role of P2X7 receptors in the development of diabetic retinopathy, World J Diabetes, 5, 141, 10.4239/wjd.v5.i2.141
Bernier, 2018, P2X receptor channels in chronic pain pathways, Br J Pharmacol, 175, 2219, 10.1111/bph.13957
Ni, 2017, Salidroside ameliorates diabetic neuropathic pain in rats by inhibiting neuroinflammation, J Mol Neurosci, 63, 9, 10.1007/s12031-017-0951-8
Luchting, 2016, Differential expression of P2X7 receptor and IL-1β in nociceptive and neuropathic pain, J Neuroinflammation, 13, 100, 10.1186/s12974-016-0565-z