Role of molecular chaperones in neurodegenerative disorders
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Kayed R, 2003, Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis. Science, 300, 486
Anton LC, 1999, Intracellular localization of proteasomal degradation of a viral antigen. J Cell Biol, 146, 113
Garcia-Mata R, 1999, Characterization and dynamics of aggresome formation by a cytosolic GFP-chimera. J Cell Biol, 146, 1239
Vidair CA, 1999, Heat shock causes protein aggregation and reduced protein solubility at the centrosome and other cytoplasmic locations. Int J Hyperthermia, 12, 681
Wigley WC, 1999, Dynamic association of proteasomal machinery with the centrosome. J Cell Biol, 145, 481
Wojcik C, 1996, Ubiquitin-mediated proteolysis centers in Hela cells—indication from atudies of an inhibitor of the chymotrypsin-like activity of the proteasome. Eur J Cell Biol, 71, 311
Johnston JA, 1898, J Cell Biol, 1998, 1883–
Ravikumar B, 2002, Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy. Hum Mol Genet, 11, 1107
Cowan K, 2003, Polyglutamine protein aggregation and toxicity are linked to the cellular stress response. Human Molec Gen, 12, 1377
Diamond MI, 2000, Regulation of expanded polyglutamine protein aggregation and nuclear localization by the glucocorticoid receptor. Proc Natl Acad Sci (USA), 97, 657
Kazantsev A, 2002, A bivalent Huntingtin binding peptide suppresses polyglutamine aggregation and pathogenesis in Drosophila. Nat Genet, 30, 367
Sanchez I, 2003, Pivotal role of oligomerization in expanded polyglutamine neurodegenerative disorders. Nature, 421, 373
Arrasate M, 2004, Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death. Nature, 431, 805
Taylor JP, 2003, Aggresomes protect cells by enhancing the degradation of toxic polyglutamine-containing protein. Hum Mol Genet, 12, 749
Sittler A, 2001, Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of Huntington's disease. Hum Mol Genet, 10, 1307
Zhou H, 2001, Chaperone suppression of cellular toxicity of huntingtin is independent of polyglutamine aggregation. J Biol Chem, 276, 48417
Chan HY, 2000, Mechanisms of chaperone suppression of polyglutamine disease: selectivity, synergy and modulation of protein solubility in Drosophila. Hum Mol Genet, 9, 2811
Auluck PK, 2002, Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease. Science, 295, 865
Schaffar G, 2004, Cellular toxicity of polyglutamine expansion proteins: mechanism of transcription factor deactivation. Mol Cell, 15, 95
Goloubinoff P, 1999, Sequential mechanism of solubilization and refolding of stable protein aggregates by a bichaperone network. Proc Natl Acad Sci (USA), 96, 13732
Takahashi R, 2003, J Neurol, 250, 11125
Imai Y, 2002, CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity. Mol Cell, 10, 55
Sugita M, 1995, Puromycin induces apoptosis of developing chick sympathetic neurons in a similar manner to NGF-deprivation. Zoological Sci, 12, 419
Garcia M, 2004, Expanded huntingtin activates the C-Jun N terminal kinase/C-Jun pathway prior to aggregate formation in striatal neurons in culture. Neuroscience, 127, 859
Martin-Aparicio E, 2001, Proteasomal-dependent aggregate reversal and absence of cell death in a conditional mouse model of Huntington's disease. J Neurosci, 21, 8772
Toussaint, 2000, Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytes. Exp Gerontol, 35, 927
Liu AY, 1989, Attenuated induction of heat shock gene expression in aging diploid fibroblasts. J Biol Chem, 264, 12037
Itahana K, 2004, Mechanisms of cellular senescence in human and mouse cells. Biogerontology, 5, 1
Bence NF, 2001, Impairment of the ubiquitin-proteasome system by protein aggregation. Science, 292, 1552
Seo H, 2004, Generalized brain and skin proteasome inhibition in Huntington's disease. Ann Neurol, 56, 319
Meredith GE, 2002, Lysosomal malfunction accompanies alpha-synuclein aggregation in a progressive mouse model of Parkinson's disease. Brain Res, 956, 156