Role of malate dehydrogenase in facilitating lactate dehydrogenase to support the glycolysis pathway in tumors

Biomedical Reports - Tập 6 Số 4 - Trang 463-467 - 2017
Siavash Mansouri1, Ali Shahriari1, Hadi Kalantar2, Taraneh Moini Zanjani3, Mojtaba Haghi Karamallah4
1Department of Biochemistry and Molecular Biology, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Khuzestan 61357‑83151, Iran
2Department of Pharmacology, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Khuzestan 61357-33184, Iran
3Department of Pharmacology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran 19857‑17443, Iran
4Department of Biochemistry and Molecular Biology, International Campus, Shahid Sadoughi University of Medical Sciences, Yazd 89151‑73143, Iran

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Hanahan, 2011, Hallmarks of cancer: The next generation, Cell, 144, 646, 10.1016/j.cell.2011.02.013

Warburg, 1956, On the origin of cancer cells, Science, 123, 309, 10.1126/science.123.3191.309

Gatenby, 2004, Why do cancers have high aerobic glycolysis?, Nat Rev Cancer, 4, 891, 10.1038/nrc1478

Talaiezadeh, 2015, Kinetic characterization of lactate dehydrogenase in normal and malignant human breast tissues, Cancer Cell Int, 15, 19, 10.1186/s12935-015-0171-7

Koukourakis, 2005, Lactate dehydrogenase 5 (LDH5) relates to up-regulated hypoxia inducible factor pathway and metastasis in colorectal cancer, Clin Exp Metastasis, 22, 25, 10.1007/s10585-005-2343-7

Rong, 2013, Lactate dehydrogenase A is overexpressed in pancreatic cancer and promotes the growth of pancreatic cancer cells, Tumour Biol, 34, 1523, 10.1007/s13277-013-0679-1

Israël, 2011, The metabolic advantage of tumor cells, Mol Cancer, 10, 70, 10.1186/1476-4598-10-70

DeBerardinis, 2008, The biology of cancer: Metabolic reprogramming fuels cell growth and proliferation, Cell Metab, 7, 11, 10.1016/j.cmet.2007.10.002

Murray, 2003, Harper's illustrated biochemistry, 26th edition

Storey, 1995, The basis of enzymatic adaptation, Principles of Medical Biology, 4, 147, 10.1016/S1569-2582(06)80008-5

Fukumura, 2007, Tumor microenvironment abnormalities: Causes, consequences, and strategies to normalize, J Cell Biochem, 101, 937, 10.1002/jcb.21187

Cairns, 2011, Regulation of cancer cell metabolism, Nat Rev Cancer, 11, 85, 10.1038/nrc2981

Grisham, 1983, The cytoplasmic malate dehydrogenase in neoplastic tissues; presence of a novel isoenzyme?, Br J Cancer, 47, 727, 10.1038/bjc.1983.113

Belfiore, 1975, Enzyme activities of NADPH-forming metabolic pathways in normal and leukemic leukocytes, Clin Chem, 21, 880, 10.1093/clinchem/21.7.880

Bradford, 1976, A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding, Anal Biochem, 72, 248, 10.1016/0003-2697(76)90527-3

Brooks, 1992, A simple computer program with statistical tests for the analysis of enzyme kinetics, Biotechniques, 13, 906

Brooks, 1994, A program for analyzing enzyme rate data obtained from a microplate reader, Biotechniques, 17, 1154

Koukourakis, 2009, Serum and tissue LDH levels in patients with breast/gynaecological cancer and benign diseases, Gynecol Obstet Invest, 67, 162, 10.1159/000183250

Koukourakis, 2009, Lactate dehydrogenase 5 expression in squamous cell head and neck cancer relates to prognosis following radical or postoperative radiotherapy, Oncology, 77, 285, 10.1159/000259260

Deberardinis, 2008, Brick by brick: Metabolism and tumor cell growth, Curr Opin Genet Dev, 18, 54, 10.1016/j.gde.2008.02.003

Robey, 2005, Hypoxia-inducible factor-1α and the glycolytic phenotype in tumors, Neoplasia, 7, 324, 10.1593/neo.04430

Allison, 2014, Identification of LDH-A as a therapeutic target for cancer cell killing via (i) p53/NAD(H)-dependent and (ii) p53-independent pathways, Oncogenesis, 3, e102, 10.1038/oncsis.2014.16

Shi, 2014, Human lactate dehydrogenase a inhibitors: A molecular dynamics investigation, PLoS One, 9, e86365, 10.1371/journal.pone.0086365

Balinsky, 1983, Isozyme patterns of normal, benign, and malignant human breast tissues, Cancer Res, 43, 5895