Role of enzymes and tissue-specific actions of steroids

Maturitas - Tập 48 - Trang 18-23 - 2004
M.J. Reed1
1Endocrinology and Metabolic Medicine, Imperial College Faculty of Medicine, St. Mary’s Hospital, London W21NY, UK

Tài liệu tham khảo

Bonney, 1983, The relationship between 17 beta-hydroxysteroid dehydrogenase activity and oestrogen concentrations in human breast tumours and in normal breast tissue, Clin. Endocrinol. (Oxford), 19, 727, 10.1111/j.1365-2265.1983.tb00051.x Pasqualini, 1989, Importance of estrogen sulfates in breast cancer, J. Steroid Biochem., 34, 1020, 10.1016/0022-4731(89)90077-0 Thijssen, 1989, Endogenous oestrogens and androgens in normal and malignant endometrial and mammary tissues, Eur. J. Cancer Clin. Oncol., 25, 1953, 10.1016/0277-5379(89)90377-5 Edery, 1981, Endogenous oestradiol-17β concentration in breast tumours determined by mass fragmentography and by radioimmunoassay: relationship to receptor content, Eur. J. Cancer, 17, 115, 10.1016/0014-2964(81)90220-6 Reed, 1989, In situ oestrone synthesis in normal breast and breast tumour tissue: effect of treatment with 4-hydroxyandrostenedione, Int. J. Cancer, 44, 233, 10.1002/ijc.2910440208 Yue, 1998, In situ aromatization enhances breast tumor estradiol levels and cellular proliferation, Cancer Res., 58, 927 Purohit, 1995, Aromatase activity and interleukin-6 production by normal and malignant breast tissues, J. Clin. Endocrinol. Metab., 80, 3052, 10.1210/jc.80.10.3052 Bulun, 1993, A link between breast cancer and local estrogen synthesis suggested by quantification of breast adipose tissue aromatase cytochrome P450 transcripts using polymerase chain reaction after reverse transcription, J. Clin. Endocrinol. Metab., 77, 1622, 10.1210/jc.77.6.1622 Macdiarmid, 1994, Reed MJ Stimulation of aromatase activity in breast fibroblasts by tumour necrosis factor-α, Mol. Cell Endocrinol., 106, 17, 10.1016/0303-7207(94)90181-3 Agarwal, 1996, Use of alternative promoters to express the aromatase cytochrome P450 (CYP19) gene in breast adipose tissues of cancer-free and breast cancer patients, J. Clin. Endocrinol. Metab., 81, 3843, 10.1210/jc.81.11.3843 Reed, 2001, Aromatase regulation and breast cancer, Clin. Endocrinol., 54, 563, 10.1046/j.1365-2265.2001.01276.x Luu-The, 2001, Analysis and characteristics of multiple types of human 17beta-hydroxysteroid dehydrogenase, J. Steroid Biochem. Mol. Biol., 76, 143, 10.1016/S0960-0760(00)00155-2 Singh, 1991, Insulin-like growth factor I and insulin-like growth factor II stimulate oestradiol-17β-hydroxysteroid dehydrogenase activity in breast cancer cells, J. Endocrinol., 129, R5, 10.1677/joe.0.129R005 Casey, 1994, 17β-hydroxysteroid dehydrogenase type 2: chromosomal assignment and progestin regulation of gene expression in human endometrium, J. Clin. Invest., 94, 2135, 10.1172/JCI117569 Kitawaki, 2000, Progesterone induction of 17beta-hydroxysteroid dehydrogenase type 2 during the secretory phase occurs in the endometrium of estrogen-dependent benign diseases but not in normal endometrium, J. Clin. Endocrinol. Metab., 85, 3292, 10.1210/jc.85.9.3292 Purohit, 1994, The hydrolysis of oestrone sulphate and dehydroepiandrosterone sulphate by human steroid sulphatase expressed in transfected COS-1 cells, J. Steroid Biochem. Mol. Biol., 50, 101, 10.1016/0960-0760(94)90177-5 Billich, 2000, Stimulation of MCF-7 breast cancer cell proliferation by estrone sulfate and dehydroepiandrosterone sulfate: inhibition by novel non-steroidal steroid sulfatase inhibitors, J. Steroid Biochem. Mol. Biol., 73, 225, 10.1016/S0960-0760(00)00077-7 Utsumi, 2000, Elevated steroid sulfatase expression in breast cancers, J. Steroid Biochem. Mol. Biol., 73, 141, 10.1016/S0960-0760(00)00060-1 Utsumi, 1999, Steroid sulfatase expression is an independent predictor of recurrence in human breast cancer, Cancer Res., 59, 377 James, 2001, Constitutive expression of the steroid sulfatase gene supports the growth of MCF-7 human breast cancer cells in vitro and in vivo, Endocrinology, 142, 1497, 10.1210/en.142.4.1497 Purohit, 1996, Regulation and inhibition of steroid sulfatase activity in breast cancer, Ann. N.Y. Acad. Sci., 784, 40, 10.1111/j.1749-6632.1996.tb16226.x Elger, 1995, Sulfamates of various estrogens are prodrugs with increased systemic and reduced hepatic estrogenicity at oral application, J. Steroid Biochem. Mol. Biol., 55, 395, 10.1016/0960-0760(95)00214-6 Chetrite, 1997, Effect of tibolone (Org OD14) and its metabolites on estrone sulphatase activity in MCF-7 and T-47D mammary cancer cells, Anticancer Res., 17, 135 Purohit, 2002, Inhibition of oestrone sulphatase activity by tibolone and its metabolites, Horm. Metab. Res., 34, 1, 10.1055/s-2002-19958 Kloosterboer, 1999, Tibolone inhibits sulfatase activity in breast but not in bone, Climacteric, 2, 322 de Gooyer, 2001, Tibolone: a compound with tissue specific inhibitory effects on sulfatase, Mol. Cell Endocrinol., 183, 55, 10.1016/S0303-7207(01)00606-2