Role of Sildenafil in Neurological Disorders

Clinical Neuropharmacology - Tập 31 Số 6 - Trang 353-362 - 2008
Muhammad Umar Farooq1, Bharath Naravetla2, Phillip Moore3, Arshad Majid2, Rishi Gupta2, Mounzer Kassab4
1Department of Neurology and Ophthalmology, Michigan State University, East Lansing, MI, USA
2Michigan State University
3BroMenn Healthcare
4Neurology and Ophthalmology

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Kruuse, 2002, The phosphodiesterase 5 inhibitor sildenafil has no effect on cerebral blood flow or blood velocity, but nevertheless induces headache in healthy subjects., J Cereb Blood Flow Metab, 22, 1124, 10.1097/00004647-200209000-00010

Desouza, 2002, Acute and prolonged effects of sildenafil on brachial artery flow-mediated dilatation in type 2 diabetes., Diabetes Care, 25, 1336, 10.2337/diacare.25.8.1336

Diomedi, 2005, Sildenafil increases cerebrovascular reactivity: a transcranial Doppler study., Neurology, 65, 919, 10.1212/01.wnl.0000173835.12308.bb

Kruuse, 2004, Plasma levels of cAMP, cGMP and CGRP in sildenafil-induced headache., Cephalalgia, 24, 547, 10.1111/j.1468-2982.2003.00712.x

Morales, 1998, Clinical safety of oral sildenafil citrate (VIAGRA) in the treatment of erectile dysfunction., Int J Impot Res, 10, 69, 10.1038/sj.ijir.3900354

Zusman, 1999, Overall cardiovascular profile of sildenafil citrate., Am J Cardiol, 83, 35C, 10.1016/S0002-9149(99)00046-6

Arnavaz, 2003, Effect of sildenafil (Viagra) on cerebral blood flow velocity: a pilot study., Psychiatry Res, 122, 207, 10.1016/S0925-4927(03)00018-0

Erceg, 2005, Oral administration of sildenafil restores learning ability in rats with hyperammonemia and with portacaval shunts., Hepatology, 41, 299, 10.1002/hep.20565

Fisher, 1980, Relation of cerebral vasospasm to subarachnoid hemorrhage visualized by computerized tomographic scanning., Neurosurgery, 6, 1, 10.1227/00006123-198001000-00001

Johnston, 2005, Effect of sildenafil (Viagra) on cerebral blood vessels., Neurology, 65, 785, 10.1212/01.wnl.0000182169.91597.6c

Dora, 2002, Exaggerated interictal cerebrovascular reactivity but normal blood flow velocities in migraine without aura., Cephalalgia, 22, 288, 10.1046/j.1468-2982.2002.00365.x

Gilad, 2002, Tonic-clonic seizures in patients taking sildenafil., BMJ, 325, 869, 10.1136/bmj.325.7369.869

Riazi, 2006, The proconvulsant effect of sildenafil in mice: role of nitric oxide-cGMP pathway., Br J Pharmacol, 147, 935, 10.1038/sj.bjp.0706680

Ballard, 1998, Effects of sildenafil on the relaxation of human corpus cavernosum tissue in vitro and on the activities of cyclic nucleotide phosphodiesterase isozymes., J Urol, 159, 2164, 10.1016/S0022-5347(01)63299-3

Shimizu-Albergine, 2003, Individual cerebellar Purkinje cells express different cGMP phosphodiesterases (PDEs): in vivo phosphorylation of cGMP-specific PDE (PDE5) as an indicator of cGMP-dependent protein kinase (PKG) activation., J Neurosci, 23, 6452, 10.1523/JNEUROSCI.23-16-06452.2003

Thompson, 1971, Multiple cyclic nucleotide phosphodiesterase activities from rat brain., Biochemistry, 10, 311, 10.1021/bi00778a018

Barnes, 2005, Phosphodiesterase 4D forms a cAMP diffusion barrier at the apical membrane of the airway epithelium., J Biol Chem, 280, 7997, 10.1074/jbc.M407521200

Burns, 1992, The catalytic subunit of protein kinase A triggers activation of the type V cyclic GMP-specific phosphodiesterase from guinea-pig lung., Biochem J, 283, 487, 10.1042/bj2830487

Omori, 2007, Overview of PDEs and their regulation., Circ Res, 100, 309, 10.1161/01.RES.0000256354.95791.f1

Yan, 2007, Regulation of phosphodiesterase 3 and inducible cAMP early repressor in the heart., Circ Res, 100, 489, 10.1161/01.RES.0000258451.44949.d7

Wheeler, 2005, Regulation of cyclic nucleotides in the urinary tract., J Smooth Muscle Res, 41, 1, 10.1540/jsmr.41.1

Inoha, 2002, Type V phosphodiesterase expression in cerebral arteries with vasospasm after subarachnoid hemorrhage in a canine model., Neurol Res, 24, 607, 10.1179/016164102101200447

Rosengarten, 2006, Sildenafil improves dynamic vascular function in the brain: studies in patients with pulmonary hypertension., Cerebrovasc Dis, 21, 194, 10.1159/000090555

Morgan, 2001, Transient ischemic attack and stroke associated with sildenafil (Viagra) use., Neurology, 57, 1730, 10.1212/WNL.57.9.1730

Habek, 2006, PetravientityD. Stroke-an adverse reaction to sildenafil., Clin Neuropharmacol, 29, 165, 10.1097/01.WNF.0000220815.86478.5F

Li, 2000, Nitric Oxide in the pathogenesis of vascular disease., J Pathol, 190, 244, 10.1002/(SICI)1096-9896(200002)190:3<244::AID-PATH575>3.0.CO;2-8

Zhang, 1996, ARL 17477, a potent and selective neuronal NOS inhibitor decreases infarct volume after transient middle cerebral artery occlusion in rats., J Cereb Blood Flow Metab, 16, 599, 10.1097/00004647-199607000-00009

Zhang, 2001, A nitric oxide donor induces neurogenesis and reduces functional deficits after stroke in rats., Ann Neurol, 50, 602, 10.1002/ana.1249

Zhang, 2003, Nitric oxide enhances angiogenesis via the synthesis of vascular endothelial growth factor and cGMP after stroke in the rat., Circ Res, 92, 308, 10.1161/01.RES.0000056757.93432.8C

Bussolati, 2001, Vascular endothelial growth factor receptor-1 modulates vascular endothelial growth factor-mediated angiogenesis via nitric oxide., Am J Pathol, 159, 993, 10.1016/S0002-9440(10)61775-0

Kroll, 1999, A novel function of VEGF receptor-2 (KDR): rapid release of nitric oxide in response to VEGF-A stimulation in endothelial cells., Biochem Biophys Res Commun, 265, 636, 10.1006/bbrc.1999.1729

Buxton, 2001, Sildenafil (Viagra)-induced spontaneous intracerebral haemorrhage., Br J Neurosurg, 15, 347, 10.1080/02688690120072513

Monastero, 2001, Intracerebral haemorrhage associated with sildenafil citrate., J Neurol, 248, 141, 10.1007/s004150170250

Marti, 2004, Hemiballism due to sildenafil use., Neurology, 63, 534, 10.1212/01.WNL.0000130359.58099.8B

Donahue, 1998, Pupil-sparing third nerve palsy associated with sildenafil citrate (Viagra)., Am J Ophthalmol, 126, 476, 10.1016/S0002-9394(98)00243-8

Laties, 2006, Ocular safety in patients using sildenafil citrate therapy for erectile dysfunction., J Sex Med, 3, 12, 10.1111/j.1743-6109.2005.00194.x

Lawes, 2004, Blood pressure and stroke: an overview of published reviews., Stroke, 35, 776, 10.1161/01.STR.0000116869.64771.5A

Ballard, 1998, Effects of sildenafil on the relaxation of human corpus cavernosum tissue in vitro and on the activities of cyclic nucleotide phosphodiesterase isozymes., J Urol, 159, 2164, 10.1016/S0022-5347(01)63299-3

Goldstein, 1998, Oral sildenafil in the treatment of erectile dysfunction. Sildenafil Study Group., N Engl J Med, 338, 1397, 10.1056/NEJM199805143382001

Brenner, 2006, Sildenafil increases cerebrovascular reactivity: a transcranial Doppler study., Neurology, 66, 1455, 10.1212/01.wnl.0000224699.75283.18

2006, Figuerola, M, Bruera O, Leston J, et al. Cluster headache attack due to sildenafil intake., Cephalalgia, 26, 617, 10.1111/j.1468-2982.2006.01071.x

Evans, 2006, Sildenafil can trigger cluster headaches., Headache, 46, 173, 10.1111/j.1526-4610.2006.00316_4.x

Inoha, 2002, Type V phosphodiesterase expression in cerebral arteries with vasospasm after subarachnoid hemorrhage in a canine model., Neurol Res, 24, 607, 10.1179/016164102101200447

Teunissen, 1996, Risk factors for subarachnoid hemorrhage: a systematic review., Stroke, 27, 544, 10.1161/01.STR.27.3.544

Gorelick, 1999, Prevention of a first stroke: a review of guidelines and a multidisciplinary consensus statement from the National Stroke Association., JAMA, 281, 1112, 10.1001/jama.281.12.1112

Solenski, 1995, Medical complications of aneurysmal subarachnoid hemorrhage: a report of the multicenter, cooperative aneurysm study. Participants of the Multicenter Cooperative Aneurysm Study., Crit Care Med, 23, 1007, 10.1097/00003246-199506000-00004

Manno, 2004, Subarachnoid hemmorhage., Neurol Clin, 22, 347, 10.1016/j.ncl.2003.12.002

Wang, 2002, Hemoglobin-induced cytotoxicity in rat cerebral cortical neurons: caspase activation and oxidative stress., Stroke, 33, 1882, 10.1161/01.STR.0000020121.41527.5D

Gandolfo, 2003, Sildenafil and transient global amnesia., Neurol Sci, 24, 145, 10.1007/s10072-003-0102-6

Savitz, 2002, Transient global amnesia after sildenafil (Viagra) use., Neurology, 59, 778, 10.1212/WNL.59.5.778

Schiefer, 2005, Transient global amnesia after intake of tadalafil, a PDE-5 inhibitor: a possible association?, Int J Impot Res, 17, 383, 10.1038/sj.ijir.3901301

Devan, 2006, Phosphodiesterase inhibition by sildenafil citrate attenuates a maze learning impairment in rats induced by nitric oxide synthase inhibition., Psychopharmacology (Berl), 183, 439, 10.1007/s00213-005-0232-z

Devan, 2004, Phosphodiesterase inhibition by sildenafil citrate attenuates the learning impairment induced by blockade of cholinergic muscarinic receptors in rats., Pharmacol Biochem Behav, 79, 691, 10.1016/j.pbb.2004.09.019

Fowler, 2005, A double blind, randomised study of sildenafil citrate for erectile dysfunction in men with multiple sclerosis., J Neurol Neurosurg Psychiatry, 76, 700, 10.1136/jnnp.2004.038695

Giammusso, 2002, Sildenafil in the treatment of erectile dysfunction in elderly depressed patients with idiopathic Parkinson's disease., Arch Gerontol Geriatr Suppl, 8, 157, 10.1016/S0167-4943(02)00124-3

Hussain, 2001, Treatment of erectile dysfunction with sildenafil citrate (Viagra) in parkinsonism due to Parkinson's disease or multiple system atrophy with observations on orthostatic hypotension., J Neurol Neurosurg Psychiatry, 71, 371, 10.1136/jnnp.71.3.371

Hurwitz, 1985, cGMP phosphodiesterase in rod and cone outer segments of the retina., J Biol Chem, 260, 568, 10.1016/S0021-9258(18)89770-8

Vobig, 1999, Retinal side-effects of sildenafil., Lancet, 353, 375, 10.1016/S0140-6736(98)05473-7

Tripathi, 2000, Branch retinal artery occlusion; another complication of sildenafil., Br J Ophthalmol, 84, 934, 10.1136/bjo.84.8.928g

Sponsel, 2000, Sildenafil and ocular perfusion., N Engl J Med, 342, 1680, 10.1056/NEJM200006013422218

Vobig, 1999, Retinal side-effects of sildenafil., Lancet, 353, 1442, 10.1016/S0140-6736(05)75965-1

Birch, 2002, A double-blind placebo-controlled evaluation of the acute effects of sildenafil citrate (Viagra) on visual function in subjects with early-stage age-related macular degeneration., Am J Ophthalmol, 133, 665, 10.1016/S0002-9394(02)01338-7

Cunningham, 2001, Anterior ischemic optic neuropathy associated with viagra., J Neuroophthalmol, 21, 22, 10.1097/00041327-200103000-00006

Egan, 2000, Sildenafil (Viagra) associated anterior ischemic optic neuropathy., Arch Ophthalmol, 118, 291

Pomeranz, 2002, Sildenafil-associated nonarteritic anterior ischemic optic neuropathy., Ophthalmology, 109, 584, 10.1016/S0161-6420(01)00976-9

Fraunfelder, 2006, Nonarteritic anterior ischemic optic neuropathy and sildenafil., Arch Ophthalmol, 124, 733, 10.1001/archopht.124.5.733

Gorkin, 2006, Sildenafil citrate use and the incidence of nonarteritic anterior ischemic optic neuropathy., Int J Clin Pract, 60, 500, 10.1111/j.1368-5031.2006.00904.x

Fowler, 2005, A double blind, randomised study of sildenafil citrate for erectile dysfunction in men with multiple sclerosis., J Neurol Neurosurg Psychiatry, 76, 700, 10.1136/jnnp.2004.038695

Giuliano, 1999, Randomized trial of sildenafil for the treatment of erectile dysfunction in spinal cord injury. Sildenafil Study Group., Ann Neurol, 46, 15, 10.1002/1531-8249(199907)46:1<15::AID-ANA5>3.0.CO;2-U

Zesiewicz, 2000, Sildenafil citrate (Viagra) for the treatment of erectile dysfunction in men with Parkinson's disease., Mov Disord, 15, 305, 10.1002/1531-8257(200003)15:2<305::AID-MDS1015>3.0.CO;2-W