Role of Renal Hypoxia in the Progression From Acute Kidney Injury to Chronic Kidney Disease
Tài liệu tham khảo
Basile, 2012, Pathophysiology of acute kidney injury, Compr Physiol, 2, 1303, 10.1002/cphy.c110041
Lameire, 2013, Acute kidney injury: an increasing global concern, Lancet, 382, 170, 10.1016/S0140-6736(13)60647-9
Benedetto, 2009, Miniaturized cardiopulmonary bypass and acute kidney injury in coronary artery bypass graft surgery, Ann Thorac Surg, 88, 529, 10.1016/j.athoracsur.2009.03.072
Uchino, 2005, Acute renal failure in critically ill patients: a multinational, multicenter study, JAMA, 294, 813, 10.1001/jama.294.7.813
Fahling, 2017, Understanding and preventing contrast-induced acute kidney injury, Nat Rev Nephrol, 13, 169, 10.1038/nrneph.2016.196
Moore, 2018, Management of acute kidney injury: core curriculum 2018, Am J Kidney Dis, 72, 136, 10.1053/j.ajkd.2017.11.021
Rifkin, 2012, Does AKI truly lead to CKD, J Am Soc Nephrol, 23, 979, 10.1681/ASN.2011121185
Ishani, 2009, Acute kidney injury increases risk of ESRD among elderly, J Am Soc Nephrol, 20, 223, 10.1681/ASN.2007080837
Amdur, 2009, Outcomes following diagnosis of acute renal failure in U.S. veterans: focus on acute tubular necrosis, Kidney Int, 76, 1089, 10.1038/ki.2009.332
Coca, 2012, Chronic kidney disease after acute kidney injury: a systematic review and meta-analysis, Kidney Int, 81, 442, 10.1038/ki.2011.379
Basile, 2016, Progression after AKI: understanding maladaptive repair processes to predict and identify therapeutic treatments, J Am Soc Nephrol, 27, 687, 10.1681/ASN.2015030309
Basile, 2004, Rarefaction of peritubular capillaries following ischemic acute renal failure: a potential factor predisposing to progressive nephropathy, Curr Opin Nephrol Hypertens, 13, 1, 10.1097/00041552-200401000-00001
Nony, 2003, Mechanisms of renal cell repair and regeneration after acute renal failure, J Pharmacol Exp Ther, 304, 905, 10.1124/jpet.102.035022
Dong, 2019, Ischemic duration and frequency determines AKI-to-CKD progression monitored by dynamic changes of tubular biomarkers in IRI mice, Front Physiol, 10, 153, 10.3389/fphys.2019.00153
Nowak, 1997, Renal cell regeneration following oxidant exposure: inhibition by TGF-beta1 and stimulation by ascorbic acid, Toxicol Appl Pharmacol, 145, 175, 10.1006/taap.1997.8166
Polichnowski, 2014, Severe renal mass reduction impairs recovery and promotes fibrosis after AKI, J Am Soc Nephrol, 25, 1496, 10.1681/ASN.2013040359
Lan, 2012, PTEN loss defines a TGF-beta-induced tubule phenotype of failed differentiation and JNK signaling during renal fibrosis, Am J Physiol Renal Physiol, 302, 1210, 10.1152/ajprenal.00660.2011
Venkatachalam, 2015, Failed tubule recovery, AKI-CKD transition, and kidney disease progression, J Am Soc Nephrol, 26, 1765, 10.1681/ASN.2015010006
Yang, 2010, Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury, Nat Med, 16, 535, 10.1038/nm.2144
Geng, 2009, Inhibition of autoregulated TGFbeta signaling simultaneously enhances proliferation and differentiation of kidney epithelium and promotes repair following renal ischemia, Am J Pathol, 174, 1291, 10.2353/ajpath.2009.080295
de Borst, 2009, c-Jun NH2-terminal kinase is crucially involved in renal tubulo-interstitial inflammation, J Pharmacol Exp Ther, 331, 896, 10.1124/jpet.109.154179
Ferenbach, 2015, Mechanisms of maladaptive repair after AKI leading to accelerated kidney ageing and CKD, Nat Rev Nephrol, 11, 264, 10.1038/nrneph.2015.3
Suzuki, 2001, Role of atrophic tubules in development of interstitial fibrosis in microembolism-induced renal failure in rat, Am J Pathol, 158, 75, 10.1016/S0002-9440(10)63946-6
Basile, 2001, Renal ischemic injury results in permanent damage to peritubular capillaries and influences long-term function, Am J Physiol Renal Physiol, 281, 887, 10.1152/ajprenal.00050.2001
Kramann, 2014, Fluorescence microangiography for quantitative assessment of peritubular capillary changes after AKI in mice, J Am Soc Nephrol, 25, 1924, 10.1681/ASN.2013101121
Basile, 2011, Impaired endothelial proliferation and mesenchymal transition contribute to vascular rarefaction following acute kidney injury, Am J Physiol Renal Physiol, 300, 721, 10.1152/ajprenal.00546.2010
Babickova, 2017, Regardless of etiology, progressive renal disease causes ultrastructural and functional alterations of peritubular capillaries, Kidney Int, 91, 70, 10.1016/j.kint.2016.07.038
Yuan, 2003, Peritubular capillary loss after mouse acute nephrotoxicity correlates with down-regulation of vascular endothelial growth factor-A and hypoxia-inducible factor-1 alpha, Am J Pathol, 163, 2289, 10.1016/S0002-9440(10)63586-9
Kwon, 2008, Preservation of peritubular capillary endothelial integrity and increasing pericytes may be critical to recovery from postischemic acute kidney injury, Am J Physiol Renal Physiol, 295, 351, 10.1152/ajprenal.90276.2008
Steegh, 2011, Early loss of peritubular capillaries after kidney transplantation, J Am Soc Nephrol, 22, 1024, 10.1681/ASN.2010050531
Shaw, 2001, Am J Pathol, 159, 2281, 10.1016/S0002-9440(10)63078-7
Ehling, 2016, Quantitative micro-computed tomography imaging of vascular dysfunction in progressive kidney diseases, J Am Soc Nephrol, 27, 520, 10.1681/ASN.2015020204
Leonard, 2008, VEGF-121 preserves renal microvessel structure and ameliorates secondary renal disease following acute kidney injury, Am J Physiol Renal Physiol, 295, 1648, 10.1152/ajprenal.00099.2008
Jung, 2009, Peritubular capillary preservation with COMP-angiopoietin-1 decreases ischemia-reperfusion-induced acute kidney injury, Am J Physiol Renal Physiol, 297, 952, 10.1152/ajprenal.00064.2009
Liu, 2014, Novel cardiolipin therapeutic protects endothelial mitochondria during renal ischemia and mitigates microvascular rarefaction, inflammation, and fibrosis, Am J Physiol Renal Physiol, 306, 970, 10.1152/ajprenal.00697.2013
Cantaluppi, 2012, Microvesicles derived from endothelial progenitor cells protect the kidney from ischemia-reperfusion injury by microRNA-dependent reprogramming of resident renal cells, Kidney Int, 82, 412, 10.1038/ki.2012.105
Lee, 2011, MMP-9 gene deletion mitigates microvascular loss in a model of ischemic acute kidney injury, Am J Physiol Renal Physiol, 301, 101, 10.1152/ajprenal.00445.2010
Xing, 2014, Mesenchymal stem cells, not conditioned medium, contribute to kidney repair after ischemia-reperfusion injury, Stem Cell Res Ther, 5, 1, 10.1186/scrt489
Lee, 2014, Id proteins regulate capillary repair and perivascular cell proliferation following ischemia-reperfusion injury, PLoS One, 9, 96
Grgic, 2012, Targeted proximal tubule injury triggers interstitial fibrosis and glomerulosclerosis, Kidney Int, 82, 172, 10.1038/ki.2012.20
Horbelt, 2007, Acute and chronic microvascular alterations in a mouse model of ischemic acute kidney injury, Am J Physiol Renal Physiol, 293, 688, 10.1152/ajprenal.00452.2006
Basile, 2007, The endothelial cell in ischemic acute kidney injury: implications for acute and chronic function, Kidney Int, 72, 151, 10.1038/sj.ki.5002312
Dimke, 2015, Tubulovascular cross-talk by vascular endothelial growth factor a maintains peritubular microvasculature in kidney, J Am Soc Nephrol, 26, 1027, 10.1681/ASN.2014010060
Basile, 2008, Renal ischemia reperfusion inhibits VEGF expression and induces ADAMTS-1, a novel VEGF inhibitor, Am J Physiol Renal Physiol, 294, 928, 10.1152/ajprenal.00596.2007
Lindenmeyer, 2007, Interstitial vascular rarefaction and reduced VEGF-A expression in human diabetic nephropathy, J Am Soc Nephrol, 18, 1765, 10.1681/ASN.2006121304
Barylski, 2009, Plasma total antioxidant activity in comparison with plasma NO and VEGF levels in patients with metabolic syndrome, Angiology, 60, 87, 10.1177/0003319708327165
Smith, 2012, Biology of the renal pericyte, Nephrol Dial Transplant, 27, 2149, 10.1093/ndt/gfs134
Lin, 2008, Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney, Am J Pathol, 173, 1617, 10.2353/ajpath.2008.080433
Lin, 2011, Targeting endothelium-pericyte cross talk by inhibiting VEGF receptor signaling attenuates kidney microvascular rarefaction and fibrosis, Am J Pathol, 178, 911, 10.1016/j.ajpath.2010.10.012
Humphreys, 2010, Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis, Am J Pathol, 176, 85, 10.2353/ajpath.2010.090517
Chen, 2011, Platelet-derived growth factor receptor signaling activates pericyte-myofibroblast transition in obstructive and post-ischemic kidney fibrosis, Kidney Int, 80, 1170, 10.1038/ki.2011.208
Kida, 2011, Pivotal role of pericytes in kidney fibrosis, Clin Exp Pharmacol Physiol, 38, 417, 10.1111/j.1440-1681.2011.05531.x
Schrimpf, 2012, Pericyte TIMP3 and ADAMTS1 modulate vascular stability after kidney injury, J Am Soc Nephrol, 23, 868, 10.1681/ASN.2011080851
Kramann, 2017, Gli1+ pericyte loss induces capillary rarefaction and proximal tubular injury, J Am Soc Nephrol, 28, 776, 10.1681/ASN.2016030297
Hansell, 2013, Determinants of kidney oxygen consumption and their relationship to tissue oxygen tension in diabetes and hypertension, Clin Exp Pharmacol Physiol, 40, 123, 10.1111/1440-1681.12034
Brezis, 1995, Hypoxia of the renal medulla—its implications for disease, N Engl J Med, 332, 647, 10.1056/NEJM199503093321006
Molema, 2012, Vascular heterogeneity in the kidney, Semin Nephrol, 32, 145, 10.1016/j.semnephrol.2012.02.001
Evans, 2013, Haemodynamic influences on kidney oxygenation: clinical implications of integrative physiology, Clin Exp Pharmacol Physiol, 40, 106, 10.1111/1440-1681.12031
Evans, 2010, Multiple mechanisms act to maintain kidney oxygenation during renal ischemia in anesthetized rabbits, Am J Physiol Renal Physiol, 298, 1235, 10.1152/ajprenal.00647.2009
Basile, 2003, Chronic renal hypoxia after acute ischemic injury: effects of L-arginine on hypoxia and secondary damage, Am J Physiol Renal Physiol, 284, 338, 10.1152/ajprenal.00169.2002
Fine, 2000, Is there a common mechanism for the progression of different types of renal diseases other than proteinuria? Towards the unifying theme of chronic hypoxia, Kidney Int., 57, 22, 10.1046/j.1523-1755.57.s75.12.x
Fine, 2008, Chronic hypoxia as a mechanism of progression of chronic kidney diseases: from hypothesis to novel therapeutics, Kidney Int., 74, 867, 10.1038/ki.2008.350
Fine, 1998, Progressive renal disease: the chronic hypoxia hypothesis, Kidney Int Suppl, 65, 74
Matsumoto, 2004, Hypoperfusion of peritubular capillaries induces chronic hypoxia before progression of tubulointerstitial injury in a progressive model of rat glomerulonephritis, J Am Soc Nephrol, 15, 1574, 10.1097/01.ASN.0000128047.13396.48
Eardley, 2008, The role of capillary density, macrophage infiltration and interstitial scarring in the pathogenesis of human chronic kidney disease, Kidney Int, 74, 495, 10.1038/ki.2008.183
Matsumoto, 2003, Induction of renoprotective gene expression by cobalt ameliorates ischemic injury of the kidney in rats, J Am Soc Nephrol, 14, 1825, 10.1097/01.ASN.0000074239.22357.06
Nordquist, 2015, Activation of hypoxia-inducible factors prevents diabetic nephropathy, J Am Soc Nephrol, 26, 328, 10.1681/ASN.2013090990
Haase, 2006, Hypoxia-inducible factors in the kidney, Am J Physiol Renal Physiol, 291, 271, 10.1152/ajprenal.00071.2006
Nangaku, 2007, Hypoxia and the HIF system in kidney disease, J Mol Med, 85, 1325, 10.1007/s00109-007-0278-y
Sun, 2009, Hypoxia-inducible factor-1alpha induces twist expression in tubular epithelial cells subjected to hypoxia, leading to epithelial-to-mesenchymal transition, Kidney Int, 75, 1278, 10.1038/ki.2009.62
Higgins, 2007, Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition, J Clin Invest, 117, 3810
Iwano, 2002, Evidence that fibroblasts derive from epithelium during tissue fibrosis, J Clin Invest, 110, 341, 10.1172/JCI0215518
Wang, 2017, Ablation of endothelial prolyl hydroxylase domain protein-2 promotes renal vascular remodelling and fibrosis in mice, J Cell Mol Med, 21, 1967, 10.1111/jcmm.13117
Liu, 2017, Signalling pathways involved in hypoxia-induced renal fibrosis, J Cell Mol Med, 21, 1248, 10.1111/jcmm.13060
Cheng, 2016, Losartan reduces ensuing chronic kidney disease and mortality after acute kidney injury, Sci Rep, 6, 34265, 10.1038/srep34265
Gewin, 2019, Transforming growth factor-beta in the acute kidney injury to chronic kidney disease transition, Nephron, 143, 154, 10.1159/000500093
Yamaguchi, 2015, Inflammation and hypoxia linked to renal injury by CCAAT/enhancer-binding protein delta, Kidney Int, 88, 262, 10.1038/ki.2015.21
Ascon, 2009, Renal ischemia-reperfusion leads to long term infiltration of activated and effector-memory T lymphocytes, Kidney Int, 75, 526, 10.1038/ki.2008.602
Burne-Taney, 2005, Persistent renal and extrarenal immune changes after severe ischemic injury, Kidney Int, 67, 1002, 10.1111/j.1523-1755.2005.00163.x
Santana, 2013, Thalidomide suppresses inflammation in adenine-induced CKD with uraemia in mice, Nephrol Dial Transplant, 28, 1140, 10.1093/ndt/gfs569
Kincaid-Smith, 1989, Polymorphs infiltrate glomeruli in mesangial IgA glomerulonephritis, Kidney Int, 36, 1108, 10.1038/ki.1989.308
Rastaldi, 2000, Glomerular monocyte-macrophage features in ANCA-positive renal vasculitis and cryoglobulinemic nephritis, J Am Soc Nephrol, 11, 2036, 10.1681/ASN.V11112036
Kinsey, 2014, Macrophage dynamics in AKI to CKD progression, J Am Soc Nephrol, 25, 209, 10.1681/ASN.2013101110
Nacu, 2008, Macrophages produce TGF-β-induced (β-ig-h3) following ingestion of apoptotic cells and regulate MMP14 levels and collagen turnover in fibroblasts, J Immunol, 180, 5036, 10.4049/jimmunol.180.7.5036
Ito, 2010, Expression patterns of connective tissue growth factor and of TGF-beta isoforms during glomerular injury recapitulate glomerulogenesis, Am J Physiol Renal Physiol, 299, 545, 10.1152/ajprenal.00120.2009
Wynn, 2016, Macrophages in tissue repair, regeneration, and fibrosis, Immunity, 44, 450, 10.1016/j.immuni.2016.02.015
Li, 2015, Rictor/mTORC2 signaling mediates TGFbeta1-induced fibroblast activation and kidney fibrosis, Kidney Int, 88, 515, 10.1038/ki.2015.119
Chung, 2018, TGF-beta promotes fibrosis after severe acute kidney injury by enhancing renal macrophage infiltration, JCI Insight, 3, 1, 10.1172/jci.insight.123563
Lech, 2014, Macrophage phenotype controls long-term AKI outcomes–kidney regeneration versus atrophy, J Am Soc Nephrol, 25, 292, 10.1681/ASN.2013020152
Mehrotra, 2017, IL-17 mediates neutrophil infiltration and renal fibrosis following recovery from ischemia reperfusion: compensatory role of natural killer cells in athymic rats, Am J Physiol Renal Physiol, 312, 385, 10.1152/ajprenal.00462.2016
Evans, 2008, Methods for studying the physiology of kidney oxygenation, Clin Exp Pharmacol Physiol, 35, 1405
Arteel, 1995, Evidence that hypoxia markers detect oxygen gradients in liver: pimonidazole and retrograde perfusion of rat liver, Br J Cancer, 72, 889, 10.1038/bjc.1995.429
Arteel, 1998, Reductive metabolism of the hypoxia marker pimonidazole is regulated by oxygen tension independent of the pyridine nucleotide redox state, Eur J Biochem, 253, 743, 10.1046/j.1432-1327.1998.2530743.x
Rosenberger, 2009, Pimonidazole adduct immunohistochemistry in the rat kidney: detection of tissue hypoxia, Methods Mol Biol, 466, 161, 10.1007/978-1-59745-352-3_12
Fong, 2016, Renal cellular hypoxia in adenine-induced chronic kidney disease, Clin Exp Pharmacol Physiol, 43, 896, 10.1111/1440-1681.12621
Ow, 2019, Detection of cellular hypoxia by pimonidazole adduct immunohistochemistry in kidney disease: Methodological pitfalls and their solution, Am J Physiol Renal Physiol, 317, 322, 10.1152/ajprenal.00219.2019
Rosenberger, 2008, Adaptation to hypoxia in the diabetic rat kidney, Kidney Int, 73, 34, 10.1038/sj.ki.5002567
Rosenberger, 2002, Expression of hypoxia-inducible factor-1α and -2α in hypoxic and ischemic rat kidneys, J Am Soc Nephrol, 13, 1721, 10.1097/01.ASN.0000017223.49823.2A
Jiang, 1996, Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension, Am J Physiol, 271, 1172, 10.1152/ajpcell.1996.271.4.C1172
Wang, 1995, Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension, Proc Natl Acad Sci U S A, 92, 5510, 10.1073/pnas.92.12.5510
Li, 2019, FoxO3 activation in hypoxic tubules prevents chronic kidney disease, J Clin Invest, 129, 2374, 10.1172/JCI122256
Rosenberger, 2007, Immunohistochemical detection of hypoxia-inducible factor-1alpha in human renal allograft biopsies, J Am Soc Nephrol, 18, 343, 10.1681/ASN.2006070792
Yu, 2013, Expression of hypoxia-inducible factor-1alpha (HIF-1alpha) in infiltrating inflammatory cells is associated with chronic allograft dysfunction and predicts long-term graft survival, Nephrol Dial Transplant, 28, 659, 10.1093/ndt/gfs377
Aukland, 1960, Renal oxygen tension, Nature, 188, 671, 10.1038/188671a0
Baumgartl, 1972, The oxygen supply of the dog kidney: measurements of intrarenal pO2, Microvasc Res, 4, 247, 10.1016/0026-2862(72)90036-2
Liss, 1997, Intrarenal oxygen tension measured by a modified Clark electrode at normal and low blood pressure and after injection of x-ray contrast media, Pflugers Arch, 434, 705, 10.1007/s004240050455
Heyman, 1991, Early renal medullary hypoxic injury from radiocontrast and indomethacin, Kidney Int, 40, 632, 10.1038/ki.1991.255
Palm, 2003, Reactive oxygen species cause diabetes-induced decrease in renal oxygen tension, Diabetologia, 46, 1153, 10.1007/s00125-003-1155-z
Warner, 2009, Regional decreases in renal oxygenation during graded acute renal arterial stenosis: a case for renal ischemia, Am J Physiol Regul Integr Comp Physiol, 296, 67, 10.1152/ajpregu.90677.2008
Ow, 2018, Absence of renal hypoxia in the subacute phase of severe renal ischemia reperfusion injury, Am J Physiol Renal Physiol, 315, 1358, 10.1152/ajprenal.00249.2018
Koeners, 2013, Telemetry-based oxygen sensor for continuous monitoring of kidney oxygenation in conscious rats, Am J Physiol Renal Physiol, 304, 1471, 10.1152/ajprenal.00662.2012
Emans, 2016, Exogenous and endogenous angiotensin-II decrease renal cortical oxygen tension in conscious rats by limiting renal blood flow, J Physiol, 594, 6287, 10.1113/JP270731
Emans, 2018, Nitric oxide synthase inhibition induces renal medullary hypoxia in conscious rats, J Am Heart Assoc, 7, 1, 10.1161/JAHA.118.009501
Prasad, 2006, Evaluation of intra-renal oxygenation by BOLD MRI, Nephron Clin Pract, 103, 58, 10.1159/000090610
Pedersen, 2005, Validation of quantitative BOLD MRI measurements in kidney: application to unilateral ureteral obstruction, Kidney Int, 67, 2305, 10.1111/j.1523-1755.2005.00334.x
Prasad, 1996, Noninvasive evaluation of intrarenal oxygenation with BOLD MRI, Circulation, 94, 3271, 10.1161/01.CIR.94.12.3271
Brezis, 1994, Determinants of intrarenal oxygenation. I. effects of diuretics, Am J Physiol, 267, 1059
Li, 2008, Blood oxygen level-dependent MR imaging of the kidneys, Magn Reson Imaging Clin N Am, 16, 613, 10.1016/j.mric.2008.07.008
Pruijm, 2018, Reduced cortical oxygenation predicts a progressive decline of renal function in patients with chronic kidney disease, Kidney Int, 93, 932, 10.1016/j.kint.2017.10.020
Prasad, 1999, Changes in renal medullary pO2 during water diuresis as evaluated by blood oxygenation level-dependent magnetic resonance imaging: effects of aging and cyclooxygenase inhibition, Kidney Int, 55, 294, 10.1046/j.1523-1755.1999.00237.x
Pruijm, 2018, Renal blood oxygenation level-dependent magnetic resonance imaging to measure renal tissue oxygenation: a statement paper and systematic review, Nephrol Dial Transplant, 33, 22, 10.1093/ndt/gfy243
Pruijm, 2010, Effect of sodium loading/depletion on renal oxygenation in young normotensive and hypertensive men, Hypertension, 55, 1116, 10.1161/HYPERTENSIONAHA.109.149682
Pohlmann, 2014, Detailing the relation between renal T2* and renal tissue pO2 using an integrated approach of parametric magnetic resonance imaging and invasive physiological measurements, Invest Radiol, 49, 547, 10.1097/RLI.0000000000000054
Kodama, 2019, Dynamic nuclear polarization magnetic resonance imaging and the oxygen-sensitive paramagnetic agent OX63 provide a noninvasive quantitative evaluation of kidney hypoxia in diabetic mice, Kidney Int, 96, 787, 10.1016/j.kint.2019.04.034
Zhu, 2018, Urinary hypoxia: an intraoperative marker of risk of cardiac surgery-associated acute kidney injury, Nephrol Dial Transplant, 33, 2191, 10.1093/ndt/gfy047
Lankadeva, 2016, Intrarenal and urinary oxygenation during norepinephrine resuscitation in ovine septic acute kidney injury, Kidney Int, 90, 100, 10.1016/j.kint.2016.02.017
Lankadeva, 2018, Urinary oxygenation as a surrogate measure of medullary oxygenation during angiotensin II therapy in septic acute kidney injury, Crit Care Med, 46, 41, 10.1097/CCM.0000000000002797
Leonhardt, 1965, Anatomy and physiology of intrarenal oxygen tension: preliminary study of the effects of anesthetics, Anesthesiology, 26, 648, 10.1097/00000542-196509000-00010
O'Hara, 2005, Simultaneous measurement of rat brain cortex PtO2 using EPR oximetry and a fluorescence fiber-optic sensor during normoxia and hyperoxia, Physiol Meas, 26, 203, 10.1088/0967-3334/26/3/006
Oostendorp, 2011, MRI of renal oxygenation and function after normothermic ischemia-reperfusion injury, NMR Biomed, 24, 194, 10.1002/nbm.1572
Hofmann, 2006, BOLD-MRI for the assessment of renal oxygenation in humans: acute effect of nephrotoxic xenobiotics, Kidney Int, 70, 144, 10.1038/sj.ki.5000418
Palm, 2004, Differentiating between effects of streptozotocin per se and subsequent hyperglycemia on renal function and metabolism in the streptozotocin-diabetic rat model, Diabetes Metab Res Rev, 20, 452, 10.1002/dmrr.472
Franzen, 2016, Pronounced kidney hypoxia precedes albuminuria in type 1 diabetic mice, Am J Physiol Renal Physiol, 310, 807, 10.1152/ajprenal.00049.2016
Ries, 2003, Renal diffusion and BOLD MRI in experimental diabetic nephropathy. Blood oxygen level-dependent, J Magn Reson Imaging, 17, 104, 10.1002/jmri.10224
Manotham, 2004, Evidence of tubular hypoxia in the early phase in the remnant kidney model, J Am Soc Nephrol, 15, 1277, 10.1097/01.ASN.0000125614.35046.10
Welch, 2003, Renal oxygenation defects in the spontaneously hypertensive rat: role of AT1 receptors, Kidney Int, 63, 202, 10.1046/j.1523-1755.2003.00729.x
Ding, 2012, Chronic treatment with tempol does not significantly ameliorate renal tissue hypoxia or disease progression in a rodent model of polycystic kidney disease, Clin Exp Pharmacol Physiol, 39, 917, 10.1111/1440-1681.12013
Ow, 2014, Determinants of renal tissue hypoxia in a rat model of polycystic kidney disease, Am J Physiol Regul Integr Comp Physiol, 307, 1207, 10.1152/ajpregu.00202.2014
Papazova, 2015, Renal transplantation induces mitochondrial uncoupling, increased kidney oxygen consumption, and decreased kidney oxygen tension, Am J Physiol Renal Physiol, 308, 22, 10.1152/ajprenal.00278.2014
Engel, 2019, Targeted VEGF therapy induces long-term renal recovery in chronic kidney disease via macrophage polarization, Hypertension, 74, 1113, 10.1161/HYPERTENSIONAHA.119.13469
Mehrotra, 2015, Th-17 cell activation in response to high salt following acute kidney injury is associated with progressive fibrosis and attenuated by AT-1R antagonism, Kidney Int, 88, 776, 10.1038/ki.2015.200
Friederich-Persson, 2013, Kidney hypoxia, attributable to increased oxygen consumption, induces nephropathy independently of hyperglycemia and oxidative stress, Hypertension, 62, 914, 10.1161/HYPERTENSIONAHA.113.01425
Luks, 2008, Chronic kidney disease at high altitude, J Am Soc Nephrol, 19, 2262, 10.1681/ASN.2007111199
Hochman, 2007, The prevalence and incidence of end-stage renal disease in Native American adults on the Navajo reservation, Kidney Int, 71, 931, 10.1038/sj.ki.5002100
Sayarlioglu, 2005, Nephropathy and retinopathy in type 2 diabetic patients living at moderately high altitude and sea level, Ren Fail, 27, 67, 10.1081/JDI-42794