Role of Hyperosmolarity in the Pathogenesis and Management of Dry Eye Disease: Proceedings of the OCEAN Group Meeting
Tóm tắt
Từ khóa
Tài liệu tham khảo
(No authors listed), 2007, 2007 Report of the International Dry Eye WorkShop (DEWS), Ocul Surf, 5, 1
Clouzeau, 2012, Hyperosmolarity potentiates toxic effects of benzalkonium chloride on conjunctival epithelial cells in vitro, Mol Vis, 18, 851
Lee, 2002, Prevalence and risk factors associated with dry eye symptoms: a population based study in Indonesia, Br J Ophthalmol, 86, 1347, 10.1136/bjo.86.12.1347
Lin, 2003, Prevalence of dry eye among an elderly Chinese population in Taiwan: the Shihpai Eye Study, Ophthalmology, 110, 1096, 10.1016/S0161-6420(03)00262-8
McCarty, 1998, The epidemiology of dry eye in Melbourne, Australia, Ophthalmology, 105, 1114, 10.1016/S0161-6420(98)96016-X
Moss, 2000, Prevalence of and risk factors for dry eye syndrome, Arch Ophthalmol, 118, 1264, 10.1001/archopht.118.9.1264
Schaumberg, 2003, Prevalence of dry eye syndrome among US women, Am J Ophthalmol, 136, 318, 10.1016/S0002-9394(03)00218-6
Schein, 1997, Prevalence of dry eye among the elderly, Am J Ophthalmol, 124, 723, 10.1016/S0002-9394(14)71688-5
Schein, 1999, Dry eye and dry mouth in the elderly: a population-based assessment, Arch Intern Med, 159, 1359, 10.1001/archinte.159.12.1359
Nichols, 2006, Patient-reported symptoms in dry dye disease, Ocul Surf, 4, 137, 10.1016/S1542-0124(12)70040-X
Miljanovic, 2007, Impact of dry eye syndrome on vision-related quality of life, Am J Ophthalmol, 143, 409, 10.1016/j.ajo.2006.11.060
Li, 2011, Anxiety and depression in patients with dry eye syndrome, Curr Eye Res, 36, 1, 10.3109/02713683.2010.519850
Stern, 1998, The pathology of dry eye: the interaction between the ocular surface and lacrimal glands, Cornea, 17, 584, 10.1097/00003226-199811000-00002
Stern, 2004, The role of the lacrimal functional unit in the pathophysiology of dry eye, Exp Eye Res, 78, 409, 10.1016/j.exer.2003.09.003
Baudouin, 2007, [A new approach for better comprehension of diseases of the ocular surface], J Fr Ophtalmol, 30, 239, 10.1016/S0181-5512(07)89584-2
Dmitrieva, 2003, High NaCl causes Mre11 to leave the nucleus, disrupting DNA damage signaling and repair, Am J Physiol Renal Physiol, 285, F266, 10.1152/ajprenal.00060.2003
Bortner, 1996, Absence of volume regulatory mechanisms contributes to the rapid activation of apoptosis in thymocytes, Am J Physiol, 271, C950, 10.1152/ajpcell.1996.271.3.C950
Galvez, 2001, A rapid and strong apoptotic process is triggered by hyperosmotic stress in cultured rat cardiac myocytes, Cell Tissue Res, 304, 279, 10.1007/s004410100358
Gilles, 1997, "Compensatory" organic osmolytes in high osmolarity and dehydration stresses: history and perspectives, Comp Biochem Physiol A Physiol, 117, 279, 10.1016/S0300-9629(96)00265-4
Yancey, 1982, Living with water stress: evolution of osmolyte systems, Science, 217, 1214, 10.1126/science.7112124
Burg, 2007, Cellular response to hyperosmotic stresses, Physiol Rev, 87, 1441, 10.1152/physrev.00056.2006
Bowlus, 1979, Solute compatibility with enzyme function and structure: rationales for the selection of osmotic agents and end-products of anaerobic metabolism in marine invertebrates, J Exp Zool, 208, 137, 10.1002/jez.1402080202
Hall, 2010, Comprehensive analysis of phosphorylation sites in Tensin1 reveals regulation by p38MAPK, Mol Cell Proteomics, 9, 2853, 10.1074/mcp.M110.003665
Brocker, 2012, The role of hyperosmotic stress in inflammation and disease, Biomol Concepts, 3, 345, 10.1515/bmc-2012-0001
Yancey, 2005, Organic osmolytes as compatible, metabolic and counteracting cytoprotectants in high osmolarity and other stresses, J Exp Biol, 208, 2819, 10.1242/jeb.01730
Corrales, 2008, Effects of osmoprotectants on hyperosmolar stress in cultured human corneal epithelial cells, Cornea, 27, 574, 10.1097/ICO.0b013e318165b19e
Pescosolido, 2009, L-carnitine and short chain ester in tears from patients with dry eye, Optom Vis Sci, 86, E132, 10.1097/OPX.0b013e318194e767
Pescosolido, 2008, Inherited ocular disorders, ophthalmic procedures and carnitines, Drugs R D, 9, 23, 10.2165/0126839-200809001-00004
Pescosolido, 2008, Ocular disorders secondary to systemic disease and the potential role of carnitines, Drugs R D, 9, 15, 10.2165/0126839-200809001-00003
Pescosolido, 2008, The aging eye and the role of L-carnitine and its derivatives, Drugs R D, 9, 3, 10.2165/0126839-200809001-00002
Garrett, 2013, Betaine stabilizes cell volume and protects against apoptosis in human corneal epithelial cells under hyperosmotic stress, Exp Eye Res, 108, 33, 10.1016/j.exer.2012.12.001
Canovas, 2007, Salt stress effects on the central and carnitine metabolisms of Escherichia coli, Biotechnol Bioeng, 96, 722, 10.1002/bit.21128
Cayley, 2003, Roles of cytoplasmic osmolytes, water, and crowding in the response of Escherichia coli to osmotic stress: biophysical basis of osmoprotection by glycine betaine, Biochemistry, 42, 12596, 10.1021/bi0347297
Peluso, 2000, Carnitine: an osmolyte that plays a metabolic role, J Cell Biochem, 80, 1, 10.1002/1097-4644(20010101)80:1<1::AID-JCB10>3.0.CO;2-W
Wood, 2001, Osmosensing and osmoregulatory compatible solute accumulation by bacteria, Comp Biochem Physiol A Mol Integr Physiol, 130, 437, 10.1016/S1095-6433(01)00442-1
Beck, 1998, Cellular response to osmotic stress in the renal medulla, Pflugers Arch, 436, 814, 10.1007/s004240050710
Pasantes-Morales, 2000, Amino acid osmolytes in regulatory volume decrease and isovolumetric regulation in brain cells: contribution and mechanisms, Cell Physiol Biochem, 10, 361, 10.1159/000016369
Maallem, 2006, Large discrepancies in cellular distribution of the tonicity-induced expression of osmoprotective genes and their regulatory transcription factor TonEBP in rat brain, Neuroscience, 142, 355, 10.1016/j.neuroscience.2006.06.028
Alfieri, 2002, Compatible osmolytes modulate the response of porcine endothelial cells to hypertonicity and protect them from apoptosis, J Physiol, 540, 499, 10.1113/jphysiol.2001.013395
Cammarata, 2002, Osmoregulatory alterations in taurine uptake by cultured human and bovine lens epithelial cells, Invest Ophthalmol Vis Sci, 43, 425
Shioda, 2002, Osmosensitive taurine transporter expression and activity in human corneal epithelial cells, Invest Ophthalmol Vis Sci, 43, 2916
Bron, 2009, Predicted phenotypes of dry eye: proposed consequences of its natural history, Ocul Surf, 7, 78, 10.1016/S1542-0124(12)70299-9
Tomlinson, 2009, Inputs and outputs of the lacrimal system: review of production and evaporative loss, Ocul Surf, 7, 186, 10.1016/S1542-0124(12)70186-6
Rolando, 1983, Increased tear evaporation in eyes with keratoconjunctivitis sicca, Arch Ophthalmol, 101, 557, 10.1001/archopht.1983.01040010557003
Tietz, 1995
Lemp, 2011, Tear osmolarity in the diagnosis and management of dry eye disease, Am J Ophthalmol, 151, 792, 10.1016/j.ajo.2010.10.032
Tomlinson, 2006, Tear film osmolarity: determination of a referent for dry eye diagnosis, Invest Ophthalmol Vis Sci, 47, 4309, 10.1167/iovs.05-1504
Versura, 2010, Performance of tear osmolarity compared to previous diagnostic tests for dry eye diseases, Curr Eye Res, 35, 553, 10.3109/02713683.2010.484557
Gilbard, 1979, Tear osmolarity and ocular surface disease in keratoconjunctivitis sicca, Arch Ophthalmol, 97, 1642, 10.1001/archopht.1979.01020020210003
Sullivan, 2010, An objective approach to dry eye disease severity, Invest Ophthalmol Vis Sci, 51, 6125, 10.1167/iovs.10-5390
Liu, 2009, A link between tear instability and hyperosmolarity in dry eye, Invest Ophthalmol Vis Sci, 50, 3671, 10.1167/iovs.08-2689
M'garrech, 2013, Impairment of lacrimal secretion in the unaffected fellow eye of patients with recurrent unilateral herpetic keratitis, Ophthalmology, 10.1016/j.ophtha.2013.02.037
Ubels, 1994, Evaluation of effects of a physiologic artificial tear on the corneal epithelial barrier: electrical resistance and carboxyfluorescein permeability, Adv Exp Med Biol, 350, 441, 10.1007/978-1-4615-2417-5_77
Li, 2006, JNK and ERK MAP kinases mediate induction of IL-1beta, TNF-alpha and IL-8 following hyperosmolar stress in human limbal epithelial cells, Exp Eye Res, 82, 588, 10.1016/j.exer.2005.08.019
Luo, 2007, Hyperosmolarity-induced apoptosis in human corneal epithelial cells is mediated by cytochrome c and MAPK pathways, Cornea, 26, 452, 10.1097/ICO.0b013e318030d259
Gaffney, 2010, A mass and solute balance model for tear volume and osmolarity in the normal and the dry eye, Prog Retin Eye Res, 29, 59, 10.1016/j.preteyeres.2009.11.002
Lechner, 2011, The molecular and cellular identity of peripheral osmoreceptors, Neuron, 69, 332, 10.1016/j.neuron.2010.12.028
Li, 2004, Stimulation of matrix metalloproteinases by hyperosmolarity via a JNK pathway in human corneal epithelial cells, Invest Ophthalmol Vis Sci, 45, 4302, 10.1167/iovs.04-0299
Solomon, 2001, Pro- and anti-inflammatory forms of interleukin-1 in the tear fluid and conjunctiva of patients with dry-eye disease, Invest Ophthalmol Vis Sci, 42, 2283
Luo, 2005, Hyperosmolar saline is a proinflammatory stress on the mouse ocular surface, Eye Contact Lens, 31, 186, 10.1097/01.ICL.0000162759.79740.46
Luo, 2004, Experimental dry eye stimulates production of inflammatory cytokines and MMP-9 and activates MAPK signaling pathways on the ocular surface, Invest Ophthalmol Vis Sci, 45, 4293, 10.1167/iovs.03-1145
Versura, 2011, Hyperosmolar stress upregulates HLA-DR expression in human conjunctival epithelium in dry eye patients and in vitro models, Invest Ophthalmol Vis Sci, 52, 5488, 10.1167/iovs.11-7215
Gilbard, 1988, Tear film osmolarity and ocular surface disease in two rabbit models for keratoconjunctivitis sicca, Invest Ophthalmol Vis Sci, 29, 374
Gilbard, 1985, Tear film osmolarity and keratoconjunctivitis sicca, CLAO J, 11, 243
Yeh, 2003, Apoptosis of ocular surface cells in experimentally induced dry eye, Invest Ophthalmol Vis Sci, 44, 124, 10.1167/iovs.02-0581
Nelson, 1984, Conjunctival goblet cell densities in ocular surface disease, Arch Ophthalmol, 102, 1049, 10.1001/archopht.1984.01040030851031
Tomlinson, 2010, Comparison of human tear film osmolarity measured by electrical impedance and freezing point depression techniques, Cornea, 29, 1036, 10.1097/ICO.0b013e3181cd9a1d
Sullivan, 2012, Correlations between commonly used objective signs and symptoms for the diagnosis of dry eye disease: clinical implications, Acta Ophthalmol
Jacobi, 2011, Tear film osmolarity measurements in dry eye disease using electrical impedance technology, Cornea, 30, 1289, 10.1097/ICO.0b013e31821de383
OcuSense. TearLab website. Available at: www.tearlab.com/.
Messmer, 2010, Hyperosmolarity of the tear film in dry eye syndrome, Dev Ophthalmol, 45, 129, 10.1159/000315026
Szalai, 2012, Evaluation of tear osmolarity in non-Sjogren and Sjogren syndrome dry eye patients with the TearLab system, Cornea, 31, 867, 10.1097/ICO.0b013e3182532047
Sullivan BD, Zmina SG, Zmina MG, et al. Real world analytical performance of the TearLab osmolarity system with an enhanced temperature sensor. Abstract: Association for Research in Vision and Ophthalmology (ARVO 2013): 4336-C0074
Khanal, 2012, Barriers to clinical uptake of tear osmolarity measurements, Br J Ophthalmol, 96, 341, 10.1136/bjo.2011.202754
Eperjesi, 2012, Reproducibility and repeatability of the OcuSense TearLab osmometer, Graefes Arch Clin Exp Ophthalmol, 250, 1201, 10.1007/s00417-012-1961-4
Gokhale, 2013, In situ osmometry: validation and effect of sample collection technique, Optom Vis Sci, 90, 359, 10.1097/OPX.0b013e31828aaf10
McCann, 2012, Effectiveness of artificial tears in the management of evaporative dry eye, Cornea, 31, 1, 10.1097/ICO.0b013e31821b71e6
Keech, 2013, Impact of time between collection and collection method on human tear fluid osmolarity, Curr Eye Res, 38, 428, 10.3109/02713683.2013.763987
Tomlinson, 2013, Effectiveness of dry eye therapy under conditions of environmental stress, Curr Eye Res, 38, 229, 10.3109/02713683.2012.757323
Benelli, 2010, Tear osmolarity measurement using the TearLab Osmolarity System in the assessment of dry eye treatment effectiveness, Cont Lens Anterior Eye, 33, 61, 10.1016/j.clae.2010.01.003
Montani, 2013, Intrasubject tear osmolarity changes with two different types of eyedrops, Optom Vis Sci, 90, 372, 10.1097/OPX.0b013e318288bdbe
Sullivan, 2012, Clinical utility of objective tests for dry eye disease: variability over time and implications for clinical trials and disease management, Cornea, 31, 1000, 10.1097/ICO.0b013e318242fd60
Aragona, 2002, Sodium hyaluronate eye drops of different osmolarity for the treatment of dry eye in Sjogren's syndrome patients, Br J Ophthalmol, 86, 879, 10.1136/bjo.86.8.879
Papa, 2001, Comparison of hypotonic and isotonic solutions containing sodium hyaluronate on the symptomatic treatment of dry eye patients, Ophthalmologica, 215, 124, 10.1159/000050842
Geerling, 2000, Quality of salivary tears following autologous submandibular gland transplantation for severe dry eye, Graefes Arch Clin Exp Ophthalmol, 238, 45, 10.1007/s004170050008
Holly, 1981, Effect of nonisotonic solutions on tear film osmolality, Invest Ophthalmol Vis Sci, 20, 236
Simmons PA, Chang-Lin J-E, Chung Q, et al. Effect of compatible solutes on transepithelial electrical resistance and uptake in primary rabbit corneal epithelial cell layers model. Abstract: Association for Research in Vision and Ophthalmology (ARVO) 2007. E-abstract #428
Loeb, 1997, The effect of erythritol on the stability of gamma-glutamyl transpeptidase and N-acetyl glucosaminidase in human urine, Toxicol Pathol, 25, 264, 10.1177/019262339702500303
Guo, 2000, Trehalose expression confers desiccation tolerance on human cells, Nat Biotechnol, 18, 168, 10.1038/72616
Matsuo, 2001, Trehalose protects corneal epithelial cells from death by drying, Br J Ophthalmol, 85, 610, 10.1136/bjo.85.5.610
Chen, 2009, Trehalose protects against ocular surface disorders in experimental murine dry eye through suppression of apoptosis, Exp Eye Res, 89, 311, 10.1016/j.exer.2009.03.015
Cejkova, 2012, Trehalose treatment accelerates the healing of UVB-irradiated corneas. Comparative immunohistochemical studies on corneal cryostat sections and corneal impression cytology, Histol Histopathol, 27, 1029
Li, 2012, Therapeutic efficacy of trehalose eye drops for treatment of murine dry eye induced by an intelligently controlled environmental system, Mol Vis, 18, 317
Foulks, 2008, Treatment of dry eye disease by the non-ophthalmologist, Rheum Dis Clin North Am, 34, 987, 10.1016/j.rdc.2008.08.008
Funke, 2012, Longitudinal analysis of taurine induced effects on the tear proteome of contact lens wearers and dry eye patients using a RP-RP-Capillary-HPLC-MALDI TOF/TOF MS approach, J Proteomics, 75, 3177, 10.1016/j.jprot.2012.03.018
Shamsi, 2007, L-carnitine protects human retinal pigment epithelial cells from oxidative damage, Curr Eye Res, 32, 575, 10.1080/02713680701363833
Willcox MD, Khandekar N, Shih S, et al. Reduction of hyperosmotic stress-induced corneal epithelial cell apoptosis by carnitine. Abstract: Association for Research in Vision and Ophthalmology (ARVO) 2012: #564/A32
Geraldine, 2006, Prevention of selenite-induced cataractogenesis by acetyl-L-carnitine: an experimental study, Exp Eye Res, 83, 1340, 10.1016/j.exer.2006.07.009
Kiyosawa, 1991, Volumetric properties of polyols (ethylene glycol, glycerol, meso-erythritol, xylitol and mannitol) in relation to their membrane permeability: group additivity and estimation of the maximum radius of their molecules, Biochim Biophys Acta, 1064, 251, 10.1016/0005-2736(91)90309-V
Guillon, 2010, Evaluation of the effects on conjunctival tissues of Optive eyedrops over one month usage, Cont Lens Anterior Eye, 33, 93, 10.1016/j.clae.2010.01.007
Davitt, 2010, Efficacy in patients with dry eye after treatment with a new lubricant eye drop formulation, J Ocul Pharmacol Ther, 26, 347, 10.1089/jop.2010.0025
Kaercher, 2009, Treatment of patients with keratoconjunctivitis sicca with Optive: results of a multicenter, open-label observational study in Germany, Clin Ophthalmol, 3, 33
Baudouin, 2012, Randomized, phase III study comparing osmoprotective carboxymethylcellulose with sodium hyaluronate in dry eye disease, Eur J Ophthalmol, 22, 751, 10.5301/ejo.5000117
Monaco, 2011, Effects of osmoprotection on symptoms, ocular surface damage, and tear film modifications caused by glaucoma therapy, Eur J Ophthalmol, 21, 243, 10.5301/EJO.2010.5730
Hardten, 2007, Evaluation of an isotonic tear in combination with topical cyclosporine for the treatment of ocular surface disease, Curr Med Res Opin, 23, 2083, 10.1185/030079907X219670
Matsuo, 2002, Trehalose eye drops in the treatment of dry eye syndrome, Ophthalmology, 109, 2024, 10.1016/S0161-6420(02)01219-8