Role of BMP signalling in peripheral CD4+ T cell proliferation

Inmunología - Tập 28 - Trang 125-130 - 2009
Alberto Varas1, Víctor G. Martínez1, Carmen Hernández-López1, Laura Hidalgo1, Ana Entrena1, Jaris Valencia1, Agustín Zapata1, Rosa Sacedón1, Angeles Vicente1
1Department of Cell Biology, Faculty of Medicine, Complutense University, Madrid

Tài liệu tham khảo

Kingsley, 1994, The TGF-β superfamily: New members, new receptors, and new genetic tests of function in different organisms, Genes Dev, 8, 133, 10.1101/gad.8.2.133 Balemans, 2002, Extracellular regulation of BMP signaling in vertebrates: A cocktail of modulators, Dev Biol, 250, 231, 10.1006/dbio.2002.0779 Gazzerro, 2007, Potential drug targets within bone morphogenetic protein signaling pathways, Curr Opin Pharmacol, 7, 325, 10.1016/j.coph.2007.01.003 Kawabata, 1998, Signal transduction by bone morphogenetic proteins, Cytokine Growth Factor Rev, 9, 49, 10.1016/S1359-6101(97)00036-1 Miyazono, 2005, BMP receptor signaling: Transcriptional targets, regulation of signals, and signaling crosstalk, Cytokine Growth Factor Rev, 16, 251, 10.1016/j.cytogfr.2005.01.009 Zwijsen, 2003, New intracellular components of bone morphogenetic protein/Smad signaling cascades, FEBS Lett, 546, 133, 10.1016/S0014-5793(03)00566-0 Miyazawa, 2002, Two major Smad pathways in TGF-β superfamily signalling, Genes Cells, 7, 1191, 10.1046/j.1365-2443.2002.00599.x Guo, 2009, Signaling cross-talk between TGF-β/BMP and other pathways, Cell Res, 19, 71, 10.1038/cr.2008.302 Urist, 1965, Bone: Formation by autoinduction, Science, 150, 893, 10.1126/science.150.3698.893 Chen, 2004, Signal transduction and biological functions of bone morphogenetic proteins, Front Biosci, 9, 349, 10.2741/1090 Bhatia, 1999, Bone morphogenetic proteins regulate the developmental program of human hematopoietic stem cells, J Exp Med, 189, 1139, 10.1084/jem.189.7.1139 Detmer, 2002, Bone morphogenetic proteins act synergistically with haematopoietic cytokines in the differentiation of haematopoietic progenitors, Cytokine, 17, 36, 10.1006/cyto.2001.0984 Grassinger, 2007, Bone morphogenetic protein (BMP)-7 but not BMP- 2 and BMP-4 improves maintenance of primitive peripheral bloodderived hematopoietic progenitor cells (HPC) cultured in serumfree medium supplemented with early acting cytokines, Cytokine, 40, 165, 10.1016/j.cyto.2007.09.004 Kersten, 2006, BMP-6 inhibits human bone marrow B lymphopoiesisupregulation of Id1 and Id3, Exp Hematol, 34, 72, 10.1016/j.exphem.2005.09.010 Kersten, 2005, BMP-6 inhibits growth of mature human B cells; induction of Smad phosphorylation and upregulation of Id1, BMC Immunol, 6, 9, 10.1186/1471-2172-6-9 Hjertner, 2001, Bone morphogenetic protein-4 inhibits proliferation and induces apoptosis of multiple myeloma cells, Blood, 97, 516, 10.1182/blood.V97.2.516 Ro, 2004, Bone morphogenetic protein-5, -6 and -7 inhibit growth and induce apoptosis in human myeloma cells, Oncogene, 23, 3024, 10.1038/sj.onc.1207386 Cejalvo, 2007, Bone morphogenetic protein-2/4 signalling pathway components are expressed in the human thymus and inhibit early T-cell development, Immunology, 121, 94, 10.1111/j.1365-2567.2007.02541.x Graf, 2002, The developmentally regulated expression of Twisted gastrulation reveals a role for bone morphogenetic proteins in the control of T cell development, J Exp Med, 196, 163, 10.1084/jem.20020276 Hager-Theodorides, 2002, Bone morphogenetic protein 2/4 signaling regulates early thymocyte differentiation, J Immunol, 169, 5496, 10.4049/jimmunol.169.10.5496 de la Pena, 2005, Fibrodysplasia ossificans progressiva (FOP), a disorder of ectopic osteogenesis, misregulates cell surface expression and trafficking of BMPRIA, J Bone Miner Res, 20, 1168, 10.1359/JBMR.050305 Sivertsen, 2007, Inhibitory effects and target genes of bone morphogenetic protein 6 in Jurkat TAg cells, Eur J Immunol, 37, 2937, 10.1002/eji.200636759 Kretzschmar, 1997, The TGF-βfamily mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase, Genes Dev, 11, 984, 10.1101/gad.11.8.984 Yamaguchi, 1996, Effects of BMP-2, BMP-4, and BMP-6 on osteoblastic differentiation of bone marrow-derived stromal cell lines, ST2 and MC3T3-G2/PA6, Biochem Biophys Res Commun, 220, 366, 10.1006/bbrc.1996.0411 Yokouchi, 1996, BMP-2/-4 mediate programmed cell death in chicken limb buds, Development, 122, 3725, 10.1242/dev.122.12.3725 Haynes, 2007, B.M.P signaling mediates stem/progenitor cell-induced retina regeneration, Proc Natl Acad Sci USA, 104, 20380, 10.1073/pnas.0708202104 Kendall, 2005, NRAGE mediates p38 activation and neural progenitor apoptosis via the bone morphogenetic protein signaling cascade, Mol Cell Biol, 25, 7711, 10.1128/MCB.25.17.7711-7724.2005