Robo4 Cooperates with Cxcr4 to Specify Hematopoietic Stem Cell Localization to Bone Marrow Niches
Tóm tắt
Từ khóa
Tài liệu tham khảo
Aiuti, 1997, The chemokine SDF-1 is a chemoattractant for human CD34+ hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34+ progenitors to peripheral blood, J. Exp. Med., 185, 111, 10.1084/jem.185.1.111
Bonig, 2009, Insights into the biology of mobilized hematopoietic stem/progenitor cells through innovative treatment schedules of the CXCR4 antagonist AMD3100, Exp. Hematol., 37, 402, 10.1016/j.exphem.2008.10.017
Broxmeyer, 2005, Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist, J. Exp. Med., 201, 1307, 10.1084/jem.20041385
Dallol, 2002, Tumour specific promoter region methylation of the human homologue of the Drosophila Roundabout gene DUTT1 (ROBO1) in human cancers, Oncogene, 21, 3020, 10.1038/sj.onc.1205421
Flomenberg, 2005, Role of CXCR4 chemokine receptor blockade using AMD3100 for mobilization of autologous hematopoietic progenitor cells, Acta Haematol., 114, 198, 10.1159/000088410
Forsberg, 2009, Parsing the niche code: The molecular mechanisms governing hematopoietic stem cell adhesion and differentiation, Haematologica, 94, 1477, 10.3324/haematol.2009.013730
Forsberg, 2005, Differential expression of novel potential regulators in hematopoietic stem cells, PLoS Genet., 1, e28, 10.1371/journal.pgen.0010028
Forsberg, 2006, New evidence supporting megakaryocyte-erythrocyte potential of flk2/flt3+ multipotent hematopoietic progenitors, Cell, 126, 415, 10.1016/j.cell.2006.06.037
Forsberg, 2010, Molecular signatures of quiescent, mobilized and leukemia-initiating hematopoietic stem cells, PLoS ONE, 5, e8785, 10.1371/journal.pone.0008785
Hooper, 2009, Engraftment and reconstitution of hematopoiesis is dependent on VEGFR2-mediated regeneration of sinusoidal endothelial cells, Cell Stem Cell, 4, 263, 10.1016/j.stem.2009.01.006
Hu, 2001, Cell-surface heparan sulfate is involved in the repulsive guidance activities of Slit2 protein, Nat. Neurosci., 4, 695, 10.1038/89482
Huminiecki, 2002, Magic roundabout is a new member of the roundabout receptor family that is endothelial specific and expressed at sites of active angiogenesis, Genomics, 79, 547, 10.1006/geno.2002.6745
Johnson, 2004, Axonal heparan sulfate proteoglycans regulate the distribution and efficiency of the repellent slit during midline axon guidance, Curr. Biol., 14, 499, 10.1016/j.cub.2004.02.005
Jones, 2008, Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability, Nat. Med., 14, 448, 10.1038/nm1742
Kaur, 2006, Robo4 signaling in endothelial cells implies attraction guidance mechanisms, J. Biol. Chem., 281, 11347, 10.1074/jbc.M508853200
Kikuta, 2000, Mobilization of hematopoietic primitive and committed progenitor cells into blood in mice by anti-vascular adhesion molecule-1 antibody alone or in combination with granulocyte colony-stimulating factor, Exp. Hematol., 28, 311, 10.1016/S0301-472X(99)00151-4
Lapidot, 2001, Mechanism of human stem cell migration and repopulation of NOD/SCID and B2mnull NOD/SCID mice. The role of SDF-1/CXCR4 interactions, Ann. N Y Acad. Sci., 938, 83, 10.1111/j.1749-6632.2001.tb03577.x
Legg, 2008, Slits and Roundabouts in cancer, tumour angiogenesis and endothelial cell migration, Angiogenesis, 11, 13, 10.1007/s10456-008-9100-x
Liles, 2003, Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100, a CXCR4 antagonist, Blood, 102, 2728, 10.1182/blood-2003-02-0663
London, 2010, Targeting Robo4-dependent Slit signaling to survive the cytokine storm in sepsis and influenza, Sci. Transl. Med., 2, ra19, 10.1126/scitranslmed.3000678
Marlow, 2008, SLITs suppress tumor growth in vivo by silencing Sdf1/Cxcr4 within breast epithelium, Cancer Res., 68, 7819, 10.1158/0008-5472.CAN-08-1357
Marlow, 2010, Vascular Robo4 restricts proangiogenic VEGF signaling in breast, Proc. Natl. Acad. Sci. USA, 107, 10520, 10.1073/pnas.1001896107
Morrison, 1997, Cyclophosphamide/granulocyte colony-stimulating factor induces hematopoietic stem cells to proliferate prior to mobilization, Proc. Natl. Acad. Sci. USA, 94, 1908, 10.1073/pnas.94.5.1908
Nagasawa, 1996, Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1, Nature, 382, 635, 10.1038/382635a0
Nie, 2008, CXCR4 is required for the quiescence of primitive hematopoietic cells, J. Exp. Med., 205, 777, 10.1084/jem.20072513
Ooi, 2009, The adhesion molecule esam1 is a novel hematopoietic stem cell marker, Stem Cells, 27, 653, 10.1634/stemcells.2008-0824
Park, 2003, Robo4 is a vascular-specific receptor that inhibits endothelial migration, Dev. Biol., 261, 251, 10.1016/S0012-1606(03)00258-6
Passegué, 2004, JunB deficiency leads to a myeloproliferative disorder arising from hematopoietic stem cells, Cell, 119, 431, 10.1016/j.cell.2004.10.010
Passegué, 2005, Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates, J. Exp. Med., 202, 1599, 10.1084/jem.20050967
Peled, 1999, Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4, Science, 283, 845, 10.1126/science.283.5403.845
Prasad, 2007, Slit-2/Robo-1 modulates the CXCL12/CXCR4-induced chemotaxis of T cells, J. Leukoc. Biol., 82, 465, 10.1189/jlb.1106678
Ross, 2008, A novel role for PECAM-1 (CD31) in regulating haematopoietic progenitor cell compartmentalization between the peripheral blood and bone marrow, PLoS ONE, 3, e2338, 10.1371/journal.pone.0002338
Sasaki, 2009, Marginal expression of CXCR4 on c-kit(+)Sca-1 (+)Lineage (-) hematopoietic stem/progenitor cells, Int. J. Hematol., 90, 553, 10.1007/s12185-009-0451-x
Seth, 2005, Magic roundabout, a tumor endothelial marker: Expression and signaling, Biochem. Biophys. Res. Commun., 332, 533, 10.1016/j.bbrc.2005.03.250
Sheldon, 2009, Active involvement of Robo1 and Robo4 in filopodia formation and endothelial cell motility mediated via WASP and other actin nucleation-promoting factors, FASEB J., 23, 513, 10.1096/fj.07-098269
Shibata, 2009, Roundabout 4 is expressed on hematopoietic stem cells and potentially involved in the niche-mediated regulation of the side population phenotype, Stem Cells, 27, 183, 10.1634/stemcells.2008-0292
Steigemann, 2004, Heparan sulfate proteoglycan syndecan promotes axonal and myotube guidance by slit/robo signaling, Curr. Biol., 14, 225, 10.1016/j.cub.2004.01.006
Suchting, 2005, Soluble Robo4 receptor inhibits in vivo angiogenesis and endothelial cell migration, FASEB J., 19, 121, 10.1096/fj.04-1991fje
Sugiyama, 2006, Maintenance of the hematopoietic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone marrow stromal cell niches, Immunity, 25, 977, 10.1016/j.immuni.2006.10.016
Watt, 2008, The central role of the chemokine receptor, CXCR4, in haemopoietic stem cell transplantation: Will CXCR4 antagonists contribute to the treatment of blood disorders?, Vox Sang., 94, 18, 10.1111/j.1423-0410.2007.00995.x
Wright, 2001, Cyclophosphamide/granulocyte colony-stimulating factor causes selective mobilization of bone marrow hematopoietic stem cells into the blood after M phase of the cell cycle, Blood, 97, 2278, 10.1182/blood.V97.8.2278
Wright, 2002, Hematopoietic stem cells are uniquely selective in their migratory response to chemokines, J. Exp. Med., 195, 1145, 10.1084/jem.20011284
Wu, 2001, The neuronal repellent Slit inhibits leukocyte chemotaxis induced by chemotactic factors, Nature, 410, 948, 10.1038/35073616