Risk of thrombosis in human atherosclerotic plaques: role of extracellular lipid, macrophage, and smooth muscle cell content.

Fuster V, Badimon L, Badimon J, Chesebro J. Mechanisms of Disease: The pathogenesis of coronary artery disease and the acute coronary syndromes I. N Engl Med 1992;326:242-50.

Fuster V, Badimon L, Badimon J, Chesebro J. The pathogenesis of coronary artery disease and the acute coronary syndrome II. N Engl Jf Med 1992;326:310-8.

Constantinides P. Plaque fissures in human coronary thrombosis. JAtheroscl Res 1966;6:1-17.

Davies MJ, Thomas AC. Plaque fissuring-the cause of acute myocardial infarction, sudden ischaemic death, and crescendo angina. BrHeartJ' 1985;53:363-73.

Falk E. Unstable angina with fatal outcome: dynamic coronary thrombosis leading to infarction and/or sudden death. Circulation 1985;71:699-708.

Levin D, Fallon J. Significance of the angiographic morphology of localized coronary stenosis: histopathologic correlations. Circulation 1982;66:316-20.

Ambrose J, Winters S, Arora R, et al. Coronary angiograph morphology in acute myocardial infarction: link between the pathogenesis of unstable angina and myocardial infarction. Jf Am Coil Cardial 1985;6: 1233-8.

Forrester J, Litvak F, Grundfest W, Hickey A. A perspective of coronary disease seen through the arteries of a living man. Circulation 1987;75:505-13.

Mizuno KM Satomura K, Miyamoto A, Arakawa K, Shibuya T, Arai T, Kurita A, Nakamura H, Ambrose JA. Angioscopic evaluation of coronary-artery thrombi in acute coronary syndromes. N Engl J Med 1992; 326:287-91.

Tracy R, Devaney K, Kissling G. Characteristics of the plaque under a coronary thrombus. Virchows Arch [A] 1985;405:411-27.

Richardson P, Davies M, Bom G. Influence of plaque configuration and stress distribution on fissuring of coronary atherosclerotic plaques. Lancet 1989;ii:941-4.

Nissen S, Gurley J, Booth D, et al. Differences in ultravascular plaque morphology in stable and unstable patients [abstr]. Circulation 1991;84:436.

Stary H. Evolution and progression of atherosclerotic lesions in coronary arteries of children and young adults. Arteriosclerosis 1989;9:1-19.

Aqel N, Ball R, Waldmann H, Mitchinson M. Monocytic origin of foam cells in human atherosclerotic plaques. Atherosclerosis 1984;53:265-71.

Kelly P, Bliss E, Morton J, Burns J, McGee J. Monoclonal antibody EBMl. High cellular specificity for human macrophages. J7 Clin Pathol 1988;41:510-5.

Skalli 0, Ropraz P, Trzeciak A, Benzonana G, Gillessen D, Gabbiani G. A monoclonal antibody against alphasmooth muscle actin: a new probe for smooth muscle differentiation. J Cell Biol 1986;103:2787-96.

Cordell J, Falini B, Erber W. Immunoenzymatic labelling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal antialkaline phosphatase (APAAP complexes). 7 Histochem Cytochem 1984;32:219-29.

Faggiotto A, Ross R. Studies of hypercholesterolaemia in non-human primates. II Fatty streak conversion to fibrous plaque. Arteriosclerosis 1984;4:341-56.

Jonasson L, Holm J, Skalli 0, Bondjers G, Hansson K. Regional accumulations of T cells, macrophages and smooth muscle cells in the human atherosclerotic plaque. Arteriosclerosis 1986;6:131-8.

Gown A, Tsukakda T, Ross R. Human atherosclerosis II immunocytochemical analysis of the cellular composition of human atherosclerotic lesions. Am JT Pathol 1986;125:191-207.

Wilcox J. Analysis of local gene expression in human atherosclerotic plaques by in-situ hybridisation. Trends Cardiovasc Med 1991;1: 17-24.

Lendon C, Davies M, Bom G, Richardson P. Atherosclerotic plaque caps are locally weakened when macrophage density is increased. Atherosclerosis 1991;65: 302-10.

Henney A, Wakeley P, Davies M, et al. Localization of stromelysin gene expression in atherosclerotic plaques by in situ hybridization. IProc Natd Acad Sci USA 1991; 88:8154-8.

Amarenco P, Duyckaerts C, Tzourio C, et al. The prevalence of ulcerated plaques in the aortic arch in patients with stroke.NEnglJMed 1992;326:221-5.

Small DM, Bond MG, Waugh D, Prack M, Sawyer JK. Physiochemical and histological changes in the arterial wall of the non-human primates during progression and regression of atherosclerosis. J Clin Invest 1984;73: 1590-1605.

Stary H. Progression and regression of experimental atherosclerosis in rhesus monkeys. In: Goldsmith E, Morr-Hankowsky J, ed. Medical primatology. Basel: S Karger, 1972:356-7.

Armstrong ML, Heistad DD, Megan MB, Lopez JA. Reversibility of atherosclerosis. Cardiovasc Clin 1990;20: 113-26.

Brown G, Albers J, Fisher L. Regression of coronary artery disease as a result of intensive lipid-lowering therapy in men with high levels of apolipoprotein B. NEnglJMed 1990;323:1289-98.