Risk of Neural Tube Defect-Affected Pregnancy Is Associated with a Block in Maternal One-Carbon Metabolism at the Level ofN-5-Methyltetrahydrofolate:Homocysteine Methyltransferase

Biochemical and Molecular Medicine - Tập 61 - Trang 28-40 - 1997
M.D. Lucock1, J. Wild1, C.H. Lumb1, M. Oliver1, R. Kendall2, I. Daskalakis1, C.J. Schorah1, M.I. Levene1
1University of Leeds Research School of Medicine, Centre for Reproduction, Growth and Development, Division of Paediatrics and Child Health, Leeds General Infirmary, D Floor, Clarendon Wing, Leeds, West Yorkshire, LS2 9NS, United Kingdom
2Department of Haematology, Leeds General Infirmary, Martin Wing, Leeds, West Yorkshire, LS1 3EX, United Kingdom