Risk factors of Lung Cancer in nonsmoker

Siegel, 2011, Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths, CA Cancer J Clin, 61, 212, 10.3322/caac.20121 2016 Parkin, 1994, At least one in seven cases of cancer is caused by smoking. Global estimates for 1985, Int J Cancer, 59, 494, 10.1002/ijc.2910590411 Ferlay, 2013 Kohler, 2011, Annual report to the nation on the status of cancer, 1975–2007, featuring tumors of the brain and other nervous system, J Natl Cancer Inst, 103, 1, 10.1093/jnci/djr077 2011, Gender empowerment and female-to-male smoking prevalence ratios, Bull World Health Organ, 89, 195, 10.2471/BLT.10.079905 2009, Lung cancer in women: the differences in epidemiology, biology and treatment outcomes, Expert Rev Resp Med, 3, 627, 10.1586/ers.09.54 Siegel, 2016, Cancer statistics, 2016, CA Cancer J Clin, 66, 7, 10.3322/caac.21332 Marchand, 1998, Associations of CYP1A1, GSTM1, and CYP2E1 polymorphisms with lung cancer suggest cell type specificities to tobacco carcinogens, Cancer Res, 58, 4858 West, 2012, A novel classification of lung cancer into molecular subtypes, PLoS One, 7, e31906, 10.1371/journal.pone.0031906 Subramaniana, 2013, Molecular profile of lung cancer in never smokers, EJC Suppl, 11, 248, 10.1016/j.ejcsup.2013.07.004 Pesch, 2012, Cigarette smoking and lung cancer—relative risk estimates for the major histological types from a pooled analysis of case control studies, Int J Cancer, 131, 1210, 10.1002/ijc.27339 Rudin, 2009, Lung cancer in never smokers: molecular profiles and therapeutic implications, Clin Cancer Res, 15, 5646, 10.1158/1078-0432.CCR-09-0377 Govindan, 2012, Genomic landscape of non-small cell lung cancer in smokers and never-smokers, Cell, 150, 1121, 10.1016/j.cell.2012.08.024 Doll, 1999, Smoking and carcinoma of the lung. Preliminary report. 1950, Bull World Health Organ, 77, 84 Gandini, 2008, Tobacco smoking and cancer: a meta-analysis, Int J Cancer, 122, 155, 10.1002/ijc.23033 Fleiss, 1991, Meta-analysis in epidemiology, with special reference to studies of the association between exposure to environmental tobacco smoke and lung cancer: a critique, J Clin Epidemiol, 44, 127, 10.1016/0895-4356(91)90261-7 Peto, 2000, Smoking, smoking cessation, and lung cancer in the UK since 1950: combination of national statistics with two case-control studies, Br Med J, 321, 323, 10.1136/bmj.321.7257.323 Parsons, 2010, Influence of smoking cessation after diagnosis of early stage lung cancer on prognosis: systematic review of observational studies with meta-analysis, Br Med J, 340, b5569, 10.1136/bmj.b5569 Guindon, 2009, 13 Dela Cruz, 2011, Lung cancer: epidemiology, etiology, and prevention, Clin Chest Med, 32, 605, 10.1016/j.ccm.2011.09.001 1988 Smith, 2000, “IARC group 2A Carcinogens” reported in cigarette mainstream smoke, Food Chem Toxicol, 38, 371, 10.1016/S0278-6915(99)00156-8 Smith, 2001, “IARC Group 2B carcinogens” reported in cigarette mainstream smoke, Food Chem Toxicol, 39, 183, 10.1016/S0278-6915(00)00164-2 Guengerich, 1997, Cytochrome P450 enzymes, Vol 3, 37 Armstrong, 1997, Glutathione-S-transferases, Vol 3, 307 Burchell, 1997, UDP-glucuronosyltransferases, Vol 3, 401 Duffel, 1997, Sulfotransferases, Vol 3, 365 Drin, 1994, Smoking-related increase in O6-alkylguanine-DNA alkyltransferase activity in human lung tissue, Carcinogenesis, 15, 1535, 10.1093/carcin/15.8.1535 Mattern, 1998, Smoking-related increase of O6-methylguanine-DNA methyltransferase expression in human lung carcinomas, Carcinogenesis, 19, 1247, 10.1093/carcin/19.7.1247 Olshan, 1997, p53 mutations in head and neck cancer: new data and evaluation of mutational spectra, Cancer Epidemiol Biomarkers Prev, 6, 499 Westra, 1993, K-ras oncogene activation in lung adenocarcinomas from former smokers. Evidence that K-ras mutations are an early and irreversible irreversible event in the development of adenocarcinoma of the lung, Cancer, 72, 432, 10.1002/1097-0142(19930715)72:2<432::AID-CNCR2820720219>3.0.CO;2-# Pryor, 1998, Fractionation of aqueous cigarette tar extracts: fractions that contain the tar radical cause DNA damage, Chem Res Toxicol, 11, 441, 10.1021/tx970159y Fielding, 1989, Studies on the ability of smoke from different types of cigarettes to induce DNA single-strand breaks in cultured human cells, Mutat Res, 214, 147, 10.1016/0027-5107(89)90208-X Matakidou, 2005, Systematic review of the relationship between family history and lung cancer risk, Br J Cancer, 93, 825, 10.1038/sj.bjc.6602769 Marshall, 2013, Genetic susceptibility to lung cancer—light at the end of the tunnel?, Carcinogenesis, 34, 487, 10.1093/carcin/bgt016 Gu, 2014, HapMap-based study on the association between MPO and GSTP1 gene polymorphisms and lung cancer susceptibilty in Chinese Han population, Acta Pharmacol Sin, 35, 636, 10.1038/aps.2014.11 Timofeeva, 2012, Influence of common genetic variation on lung cancer risk: meta-analysis of 14,900 cases and 29,485 controls, Hum Mol Genet, 21, 4980, 10.1093/hmg/dds334 Spitz, 2007, A risk model for prediction of lung cancer, J Natl Cancer Inst, 99, 715, 10.1093/jnci/djk153 Sedgwick, 2004, Repairing DNA-methylation damage, Nat Rev Mol Cell Biol, 5, 148, 10.1038/nrm1312 Wang, 2015, Genetic association between angiotensinogen polymorphisms and lung cancer risk, Medicine, 94, e1250, 10.1097/MD.0000000000001250 McLemore, 1990, Expression of CYP1A1 gene in patients withlung cancer: evidence for cigarette smoke-induced gene expression in normal lung tissue and for altered gene regulation in primary pulmonary carcinomas, J Natl Cancer Inst, 82, 1333, 10.1093/jnci/82.16.1333 Gao, 1999, Polymorphisms of the GSTM1 and CYP2D6 genes associated with susceptibility to lung cancer in Chinese, Mutat Res, 444, 441, 10.1016/S1383-5718(99)00092-3 Spurr, 1995, Polymorphisms in drug-metabolizing enzymes as modifiers of cancer risk, Clin Chem, 41, 1864, 10.1093/clinchem/41.12.1864 Bouchardy, 1998, N-acetyltransferase NAT1 and NAT2 genotypes and lung cancer risk, Pharmacogenetics, 8, 291, 10.1097/00008571-199808000-00002 Fernández-Rubio, 2008, The TP53 Arg72Pro polymorphism and lung cancer risk in a population of Northern Spain, Lung Cancer, 61, 309, 10.1016/j.lungcan.2008.01.017 Choi, 2009, Polymorphisms in telomere maintenance genes and risk of lung cancer, Cancer Epidemiol Biomarkers Prev, 18, 2773, 10.1158/1055-9965.EPI-09-0323 Hosgood, 2009, Genetic variation in telomere maintenance genes, telomere length, and lung cancer susceptibility, Lung Cancer, 66, 157, 10.1016/j.lungcan.2009.02.005 Brenner, 2012, Previous lung diseases and lung cancer risk: a pooled analysis from the international lung cancer consortium, Am J Epidemiol, 176, 573, 10.1093/aje/kws151 Wang, 2012, Association between chronic obstructive pulmonary disease and lung cancer: a case-control study in southern Chinese and a meta-analysis, PLoS ONE, 7, e46144, 10.1371/journal.pone.0046144 Young, 2009, COPD prevalence is increased in lung cancer, independent of age, sex and smoking history, Eur Respir J, 34, 380, 10.1183/09031936.00144208 Liang, 2009, Facts and fiction of the relationship between preexisting tuberculosis and lung cancer risk: a systematic review, Int J Cancer, 125, 2936, 10.1002/ijc.24636 Shepshelovich, 2016, High lung cancer incidence in heavy smokers following hospitalization due to pneumonia, Am J Med, 129, 332, 10.1016/j.amjmed.2015.10.030 Caramori, 2011, Unbalanced oxidant-induced DNA damage and repair inCOPD: a link towards lung cancer, Thorax, 66, 521, 10.1136/thx.2010.156448 Lin, 2007, A cytokine-mediated link between innate immunity, inflammation, and cancer, J Clin Invest, 117, 1175, 10.1172/JCI31537 Azad, 2008, Inflammation and lung cancer: roles of reactive oxygen/nitrogen species, J Toxicol Environ Health B Crit Rev, 11, 1, 10.1080/10937400701436460 Kobliakov, 2010, Mechanisms of tumor promotion by reactive oxygen species, Biochemistry (Mosc), 75, 675, 10.1134/S0006297910060015 Robinson, 2016, Molecular evidence of viral DNA in non-small cell lung cancer and non-neoplastic lung, Br J Cancer, 115, 497, 10.1038/bjc.2016.213 Ragin, 2014, HPV-associated lung cancers: an international pooled analysis, Carcinogenesis, 35, 1267, 10.1093/carcin/bgu038 Yu, 2009, Correlation of HPV-16/18 infection of human papillomavirus with lung squamous cell carcinomas in Western China, Oncol Rep, 21, 1627 Srinivasan, 2009, Human papillomavirus type 16 and 18 in primary lung cancers–a meta-analysis, Carcinogenesis, 30, 1722, 10.1093/carcin/bgp177 Muñoz, 2012, Functional interaction between human papillomavirus type 16 E6 and E7 oncoproteins and cigarette smoke components in lung epithelial cells, PLoS ONE, 7, e38178, 10.1371/journal.pone.0038178 Kinoshita, 1995, Human papillomavirus type 18 DNA and E6-E7 mRNA are detected in squamous cell carcinoma and adenocarcinoma of the lung, Br J Cancer, 71, 344, 10.1038/bjc.1995.69 Zhai, 2015, HPV and lung cancer risk: a meta-analysis, J Clin Virol, 63, 84, 10.1016/j.jcv.2014.09.014 Cheng, 2008, Human papillomavirus type 16/18 up-regulates the expression of interleukin-6 and antiapoptotic Mcl-1 in non–small cell lung cancer, Clin Cancer Res, 14, 4705, 10.1158/1078-0432.CCR-07-4675 Serraino, 2000, Cancer risk among men with, or at risk of, HIV infection in southern Europe, AIDS, 14, 553, 10.1097/00002030-200003310-00011 el-Solh, 1997, An RGD containing peptide from HIV-1 tat-(65-80) modulates protooncogene expression in human bronchoalveolar carcinoma cell line, A549, Immunol Invest, 26, 351, 10.3109/08820139709022692 Tong, 2009, Decreased TIP30 expression promotes tumor metastasis in lung cancer, Am J Pathol, 174, 1931, 10.2353/ajpath.2009.080846 Shebl, 2010, Pulmonary infections and risk of lung cancer among persons with AIDS, J Acquir Immune Defic Syndr, 55, 375, 10.1097/QAI.0b013e3181eef4f7 Hessol, 2015, Lung cancer incidence and survival among HIV-infected and uninfected women and men, AIDS, 29, 1183, 10.1097/QAD.0000000000000690 Kutok, 2006, Spectrum of Epstein-Barr virus-associated diseases, Annu Rev Pathol, 1, 375, 10.1146/annurev.pathol.1.110304.100209 Conway, 1996, Absence of evidence for an etiologic role for Epstein-Barr virus in neoplasms of the lung and pleura, Mod Pathol, 9, 491 Castro, 2001, Relationship between Epstein-Barr virus and lymphoepithelioma-like carcinoma of the lung: a clinicopathologic study of 6 cases and review of the literature, Hum Pathol, 32, 863, 10.1053/hupa.2001.26457 Jones, 1996, Asbestos exposure, asbestosis, and asbestos-attributable lung cancer, Thorax, 51, S9, 10.1136/thx.51.Suppl_2.S9 Egilman, 1996, Lung cancer and asbestos exposure: asbestosis is not necessary, Am J Ind Med, 30, 398, 10.1002/(SICI)1097-0274(199610)30:4<398::AID-AJIM4>3.0.CO;2-S Hessel, 2005, Asbestos, asbestosis, and lung cancer: a critical assessment of the epidemiological evidence, Thorax, 60, 433, 10.1136/thx.2004.037267 Weiss, 1999, Asbestosis: a marker for the increased risk of lung cancer among workers exposed to asbestos, Chest, 115, 536, 10.1378/chest.115.2.536 Straif, 2009, WHO International Agency for Research on Cancer Monograph Working Group. A review of human carcinogens—Part C: metals, arsenic, dusts, and fibres, Lancet Oncol, 10, 453, 10.1016/S1470-2045(09)70134-2 Gulumian, 2005, An update on the detoxification processes for silica particles and asbestos fibers: successess and limitations, J Toxicol Environ Health B Crit Rev, 8, 453, 10.1080/10937400590952547 Huang, 2011, Role of mutagenicity in asbestos fiber-induced carcinogenicity and other diseases, J Toxicol Environ Health B Crit Rev, 14, 179, 10.1080/10937404.2011.556051 Samet, 2006, Residential radon and lung cancer: end of the story?, J Toxicol Environ Health A, 69, 527, 10.1080/15287390500260879 Grosche, 2006, Lung cancer risk among German male uranium miners: a cohort study, 1946–1998, Br J Cancer, 95, 1280, 10.1038/sj.bjc.6603403 Lubin, 1995, Lung cancer in radon-exposed miners and estimation of risk from indoor exposure, J Natl Cancer Inst, 87, 817, 10.1093/jnci/87.11.817 Samet, 1994, Indoor radon and lung cancer: risky or not?, J Natl Cancer Inst, 86, 1813, 10.1093/jnci/86.24.1813 Saccomanno, 1988, Relationship of radioactive radon daughters and cigarette smoking in the genesis of lung cancer in uranium miners, Cancer, 62, 1402, 10.1002/1097-0142(19881001)62:7<1402::AID-CNCR2820620727>3.0.CO;2-K Robertson, 2013, The cellular and molecular carcinogenic effects of radon exposure: a review, Int J Mol Sci, 14, 14024, 10.3390/ijms140714024 Al-Zoughool, 2009, Health effects of radon: a review of the literature, Int J Radiat Biol, 85, 57, 10.1080/09553000802635054 Narayanan, 1997, Alpha particles initiate biological production of superoxide anions and hydrogen peroxide in human cells, Cancer Res, 57, 3963 Liu, 2013, Exposure-response analysis and risk assessment for lung cancer in relationship to silica exposure: a 44-year cohort study of 34,018 workers, Am J Epidemiol, 178, 1424, 10.1093/aje/kwt139 Consonni, 2015, Lung cancer risk among bricklayers in a pooled analysis of case-control studies, Int J Cancer, 136, 360, 10.1002/ijc.28986 Freire, 2013, Montuenga silica-induced chronic inflammation promotes lung carcinogenesis in the context of an immunosuppressive microenvironment, Neoplasia, 15, 913, 10.1593/neo.13310 Putila, 2011, Minna association of arsenic exposure with lung cancer incidence rates in the United States, PLoS ONE, 6, e25886, 10.1371/journal.pone.0025886 Németi, 2010, Polynucleotide phosphorylase and mitochondrial ATP synthase mediate reduction of arsenate to the more toxic arsenite by forming arsenylated analogues of ADP and ATP, Toxicol Sci, 117, 270, 10.1093/toxsci/kfq141 Shi, 2004, Oxidative mechanism of arsenic toxicity and carcinogenesis, Mol Cell Biochem, 255, 67, 10.1023/B:MCBI.0000007262.26044.e8 Chen, 2011, Estrogen promotes benzo [alpha] pyrene induced lung carcinogenesis through oxidative damage and cytochrome c-mediated caspace-3 activation pathways in female mice, Cancer Lett, 308, 14, 10.1016/j.canlet.2011.04.007 Kerr, 2008, Steroid receptor and growth factor receptor expression in human nonsmall cell lung cancers using cells procured by laser-capture microdissection, Adv Exp Med Biol, 617, 377, 10.1007/978-0-387-69080-3_36 Morani, 2008, Biological functions and clinical implications of oestrogen receptors alfa and beta in epithelial tissues, J Intern Med, 264, 128, 10.1111/j.1365-2796.2008.01976.x Hershberger, 2009, Estrogen receptor beta subtype-specific ligands increase transcription, p44/p42 mitogen activated protein kinase (MAPK) activation and growth in human non-small cell lung cancer cells, J Steroid Biochem Mol Biol, 116, 102, 10.1016/j.jsbmb.2009.05.004 Stabile, 2005, Combined targeting of the estrogen receptor and the epidermal growth factor receptor in non-small cell lung cancer shows enhanced antiproliferative effects, Cancer Res, 65, 1459, 10.1158/0008-5472.CAN-04-1872 Hershberger, 2005, Regulation of endogenous gene expression in human non-small cell lung cancer cells by estrogen receptor ligands, Cancer Res, 65, 1598, 10.1158/0008-5472.CAN-04-2694 Hsu, 2015, Estrogen adversely affects the prognosis of patients with lung adenocarcinoma, Cancer Sci, 106, 51, 10.1111/cas.12558 Price, 1992, Relative expression of aromatase cytochrome P450 in human fetal tissues as determined by competitive polymerase chain reaction amplification, J Clin Endocrinol Metab, 74, 879, 10.1210/jcem.74.4.1548354 Simpson, 2004, Aromatase: biologic relevance of tissue-specific expression, Semin Reprod Med, 22, 11, 10.1055/s-2004-823023 Weinberg, 2005, Aromatase inhibitors in human lungcancer therapy, Cancer Res, 65, 11287, 10.1158/0008-5472.CAN-05-2737 Omenn, 1996, Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease, N Engl J Med, 334, 1150, 10.1056/NEJM199605023341802 Woodson, 1999, Serum alpha-tocopherol and subsequent risk of lung cancer among male smokers, J Natl Cancer Inst, 91, 1738, 10.1093/jnci/91.20.1738 Hosseini, 2014, Nutrition and lung cancer: a case control study in Iran, BMC Cancer, 14, 860, 10.1186/1471-2407-14-860 Pan, 2004, Association of obesity and cancer risk in Canada, Am J Epidemiol, 159, 259, 10.1093/aje/kwh041 Deneo-Pellegrini, 1996, Meat consumption and risk of lung cancer: a case-control study from Uruguay, Lung Cancer, 14, 195, 10.1016/0169-5002(95)00546-3 Bandera, 2001, Alcohol consumption and lung cancer: a review of the epidemiologic evidence, Cancer Epidemiol Biomarkers Prev, 10, 813 Fehringer, 2017, Alcohol and lung cancer risk among never smokers: A pooled analysis from the international lung cancer consortium and the SYNERGY study, Int J Cancer, 140, 1976, 10.1002/ijc.30618 Bagnardi, 2015, Alcohol consumption and site-specific cancer risk: a comprehensive dose-response meta-analysis, Br J Cancer, 112, 580, 10.1038/bjc.2014.579 Pollack, 1984, Prospective study of alcohol consumption and cancer, N Engl J Med, 310, 617, 10.1056/NEJM198403083101003 Chao, 2007, Associations between beer, wine, and liquor consumption and lung cancer risk: a meta-analysis, Cancer Epidemiol Biomarkers Prev, 16, 2436, 10.1158/1055-9965.EPI-07-0386 Ahrendt, 2000, Alcohol consumption and cigarette smoking increase the frequency of p53 mutations in non-small cell lung cancer, Cancer Res, 60, 3155 Liu, 2004, Vegetables, fruit consumption and risk of lung cancer among middle-aged Japanese men and women: JPHC study, Cancer Causes Control, 15, 349, 10.1023/B:CACO.0000027507.22124.20 Hart, 2004, Cannabinoids induce cancer cell proliferation via tumor necrosis factor alpha converting enzyme (TACE/ADAM17)-mediated transactivation of the epidermal growth factor receptor, Cancer Res, 64, 1943, 10.1158/0008-5472.CAN-03-3720 Aldington, 2008, Cannabis use and risk of lung cancer: a case-control study, Eur Respir J, 31, 280, 10.1183/09031936.00065707 Luo, 1996, Indoor burning coal air pollution and lung cancer—a case-control study in Fuzhou, China, Lung Cancer, 14, S113, 10.1016/S0169-5002(96)90217-2 Kleinerman, 2002, Lung cancer and indoor exposure to coal and biomass in rural China, J Occup Environ Med, 44, 338, 10.1097/00043764-200204000-00014 Hosgood, 2010, In-home coal and wood use and lung cancer risk: a pooled analysis of the International Lung Cancer Consortium, Environ Health Perspect, 118, 1743, 10.1289/ehp.1002217 Pope, 2002, Lung cancer, cardiopulmonary mortality, and long-term exposure to fine particulate air pollution, J Am Med Assoc, 287, 1132, 10.1001/jama.287.9.1132 Loomis, 2013, The carcinogenicity of outdoor air pollution, Lancet Oncol, 4, 1263 Sram, 2007, Environmental exposure to carcinogenic polycyclic aromatic hydrocarbons –the interpretation of cytogenetic analysis by FISH, Toxicol Lett, 172, 12, 10.1016/j.toxlet.2007.05.019 Chen, 1999, Analysis of chromosomal aberration in peripheral blood lymphocytes from traffic policemen, J Hygiene Res, 6, 324 Chen, 2015, Traffic-related air pollution and lung cancer: a meta-analysis, Thoracic Cancer, 6, 307, 10.1111/1759-7714.12185 Gu, 2010, Systematic review of the relationship between family history of lung cancer and lung cancer risk, Zhongguo Fei Ai Za Zhi, 13, 224 Coté, 2012, Increased risk of lung cancer in individuals with a family history of the disease: a pooled analysis from the International Lung Cancer Consortium, Eur J Cancer, 48, 1957, 10.1016/j.ejca.2012.01.038 Gao, 2009, Family history of cancer and non-malignant lung diseases as risk factors for lung cancer, Int J Cancer, 125, 146, 10.1002/ijc.24283