Ribose 2′-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5

Nature Immunology - Tập 12 Số 2 - Trang 137-143 - 2011
Roland Züst1,2, Luisa Cervantes‐Barragán1, Matthias Habjan1, Reinhard Maier1, Benjamin W. Neuman3, John Ziebuhr4,5, Kristy J. Szretter6, Susan C. Baker7, Winfried Barchet8, Michael Diamond6, Stuart G. Siddell9, Burkhard Ludewig1,10, Volker Thiel1,10
1Institute of Immunobiology, Kantonal Hospital St. Gallen, St. Gallen, Switzerland
2Present address: Singapore Immunology Network, Agency for Science, Technology and Research, Singapore.,
3School of Biological Sciences, University of Reading, Reading, UK
4Centre for Infection and Immunity, Queen's University Belfast, Belfast, UK
5Institute of Medical Virology, Justus Liebig University Giessen, Giessen, Germany
6Department of Medicine, Department of Molecular Microbiology, and Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, USA
7Department of Microbiology and Immunology, Loyola University Stritch School of Medicine, Maywood, USA
8Institute for Clinical Chemistry and Pharmacology, University Hospital, University of Bonn, Bonn, Germany
9Department of Cellular and Molecular Medicine, School of Medical and Veterinary Sciences, University of Bristol, Bristol, UK
10Vetsuisse Faculty, University of Zurich, Zurich, Switzerland

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