Revert the SIRT: Normalizing SIRT1 Activity in Myelodysplastic Stem Cells
Tài liệu tham khảo
Anderson, 2014, SnapShot: Mammalian sirtuins, Cell, 159, 956e1, 10.1016/j.cell.2014.10.045
Chalkiadaki, 2015, The multifaceted functions of sirtuins in cancer, Nat. Rev. Cancer, 15, 608, 10.1038/nrc3985
Dai, 2018, Sirtuin activators and inhibitors: Promises, achievements, and challenges, Pharmacol. Ther., 188, 140, 10.1016/j.pharmthera.2018.03.004
Haferlach, 2014, Landscape of genetic lesions in 944 patients with myelodysplastic syndromes, Leukemia, 28, 241, 10.1038/leu.2013.336
Leko, 2012, SIRT1 is dispensable for function of hematopoietic stem cells in adult mice, Blood, 119, 1856, 10.1182/blood-2011-09-377077
Li, 2012, Activation of p53 by SIRT1 inhibition enhances elimination of CML leukemia stem cells in combination with imatinib, Cancer Cell, 21, 266, 10.1016/j.ccr.2011.12.020
Li, 2014, SIRT1 activation by a c-MYC oncogenic network promotes the maintenance and drug resistance of human FLT3-ITD acute myeloid leukemia stem cells, Cell Stem Cell, 15, 431, 10.1016/j.stem.2014.08.001
Liu, 2013, Decreased 5-hydroxymethylcytosine levels are associated with TET2 mutation and unfavorable overall survival in myelodysplastic syndromes, Leuk. Lymphoma, 54, 2466, 10.3109/10428194.2013.778408
Singh, 2013, Sirt1 ablation promotes stress-induced loss of epigenetic and genomic hematopoietic stem and progenitor cell maintenance, J. Exp. Med., 210, 987, 10.1084/jem.20121608
Sun, 2018, SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function, Cell Stem Cell, 23, 355, 10.1016/j.stem.2018.07.018