Reversible Inhibition of PSD-95 mRNA Translation by miR-125a, FMRP Phosphorylation, and mGluR Signaling
Tóm tắt
Từ khóa
Tài liệu tham khảo
Abu-Elneel, 2008, Heterogeneous dysregulation of microRNAs across the autism spectrum, Neurogenetics, 9, 153, 10.1007/s10048-008-0133-5
Anwyl, 2009, Metabotropic glutamate receptor-dependent long-term potentiation, Neuropharmacology, 56, 735, 10.1016/j.neuropharm.2009.01.002
Auerbach, 2010, Loss of the fragile X mental retardation protein decouples metabotropic glutamate receptor dependent priming of long-term potentiation from protein synthesis, J. Neurophysiol., 104, 1047, 10.1152/jn.00449.2010
Bagni, 2005, From mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndrome, Nat. Rev. Neurosci., 6, 376, 10.1038/nrn1667
Banerjee, 2009, A coordinated local translational control point at the synapse involving relief from silencing and MOV10 degradation, Neuron, 64, 871, 10.1016/j.neuron.2009.11.023
Bartel, 2004, MicroRNAs: genomics, biogenesis, mechanism, and function, Cell, 116, 281, 10.1016/S0092-8674(04)00045-5
Bassell, 2008, Fragile X syndrome: loss of local mRNA regulation alters synaptic development and function, Neuron, 60, 201, 10.1016/j.neuron.2008.10.004
Bhattacharyya, 2006, Relief of microRNA-mediated translational repression in human cells subjected to stress, Cell, 125, 1111, 10.1016/j.cell.2006.04.031
Bhattacharyya, 2009, A critical role for PSD-95/AKAP interactions in endocytosis of synaptic AMPA receptors, Nat. Neurosci., 12, 172, 10.1038/nn.2249
Bingol, 2004, A proteasome-sensitive connection between PSD-95 and GluR1 endocytosis, Neuropharmacology, 47, 755, 10.1016/j.neuropharm.2004.07.028
Bramham, 2007, Dendritic mRNA: transport, translation and function, Nat. Rev. Neurosci., 8, 776, 10.1038/nrn2150
Brodersen, 2009, Revisiting the principles of microRNA target recognition and mode of action, Nat. Rev. Mol. Cell Biol., 10, 141, 10.1038/nrm2619
Ceman, 1999, Isolation of an FMRP-associated messenger ribonucleoprotein particle and identification of nucleolin and the fragile X-related proteins as components of the complex, Mol. Cell. Biol., 19, 7925, 10.1128/MCB.19.12.7925
Ceman, 2003, Phosphorylation influences the translation state of FMRP-associated polyribosomes, Hum. Mol. Genet., 12, 3295, 10.1093/hmg/ddg350
Chang, 2009, Small regulatory RNAs in neurodevelopmental disorders, Hum. Mol. Genet., 18, R18, 10.1093/hmg/ddp072
Colledge, 2003, Ubiquitination regulates PSD-95 degradation and AMPA receptor surface expression, Neuron, 40, 595, 10.1016/S0896-6273(03)00687-1
De Roo, 2008, Activity-dependent PSD formation and stabilization of newly formed spines in hippocampal slice cultures, Cereb. Cortex, 18, 151, 10.1093/cercor/bhm041
Edbauer, 2010, Regulation of synaptic structure and function by FMRP-associated microRNAs miR-125b and miR-132, Neuron, 65, 373, 10.1016/j.neuron.2010.01.005
Fan, 2009, Interaction of postsynaptic density protein-95 with NMDA receptors influences excitotoxicity in the yeast artificial chromosome mouse model of Huntington's disease, J. Neurosci., 29, 10928, 10.1523/JNEUROSCI.2491-09.2009
Filipowicz, 2008, Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?, Nat. Rev. Genet., 9, 102, 10.1038/nrg2290
Gardoni, 1998, Calcium/calmodulin-dependent protein kinase II is associated with NR2A/B subunits of NMDA receptor in postsynaptic densities, J. Neurochem., 71, 1733, 10.1046/j.1471-4159.1998.71041733.x
Ha, 1996, A bulged lin-4/lin-14 RNA duplex is sufficient for Caenorhabditis elegans lin-14 temporal gradient formation, Genes Dev., 10, 3041, 10.1101/gad.10.23.3041
Jin, 2004, Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway, Nat. Neurosci., 7, 113, 10.1038/nn1174
Kye, 2007, Somatodendritic microRNAs identified by laser capture and multiplex RT-PCR, RNA, 13, 1224, 10.1261/rna.480407
Lee, 1993, The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14, Cell, 75, 843, 10.1016/0092-8674(93)90529-Y
Lee, 2008, miR-19, miR-101 and miR-130 co-regulate ATXN1 levels to potentially modulate SCA1 pathogenesis, Nat. Neurosci., 11, 1137, 10.1038/nn.2183
Lugli, 2005, Dicer and eIF2c are enriched at postsynaptic densities in adult mouse brain and are modified by neuronal activity in a calpain-dependent manner, J. Neurochem., 94, 896, 10.1111/j.1471-4159.2005.03224.x
Martin, 2009, mRNA localization: gene expression in the spatial dimension, Cell, 136, 719, 10.1016/j.cell.2009.01.044
Muddashetty, 2007, Dysregulated metabotropic glutamate receptor-dependent translation of AMPA receptor and postsynaptic density-95 mRNAs at synapses in a mouse model of fragile X syndrome, J. Neurosci., 27, 5338, 10.1523/JNEUROSCI.0937-07.2007
Narayanan, 2007, FMRP phosphorylation reveals an immediate-early signaling pathway triggered by group I mGluR and mediated by PP2A, J. Neurosci., 27, 14349, 10.1523/JNEUROSCI.2969-07.2007
Narayanan, 2008, S6K1 phosphorylates and regulates fragile X mental retardation protein (FMRP) with the neuronal protein synthesis-dependent mammalian target of rapamycin (mTOR) signaling cascade, J. Biol. Chem., 283, 18478, 10.1074/jbc.C800055200
Nikonenko, 2008, PSD-95 promotes synaptogenesis and multiinnervated spine formation through nitric oxide signaling, J. Cell Biol., 183, 1115, 10.1083/jcb.200805132
Nottrott, 2006, Human let-7a miRNA blocks protein production on actively translating polyribosomes, Nat. Struct. Mol. Biol., 13, 1108, 10.1038/nsmb1173
Pan, 2010, Dendritic spine instability and insensitivity to modulation by sensory experience in a mouse model of fragile X syndrome, Proc. Natl. Acad. Sci. USA, 107, 17768, 10.1073/pnas.1012496107
Richter, 2008, Think you know how miRNAs work? Think again, Nat. Struct. Mol. Biol., 15, 334, 10.1038/nsmb0408-334
Ro, 2006, A PCR-based method for detection and quantification of small RNAs, Biochem. Biophys. Res. Commun., 351, 756, 10.1016/j.bbrc.2006.10.105
Ronesi, 2008, Homer interactions are necessary for metabotropic glutamate receptor-induced long-term depression and translational activation, J. Neurosci., 28, 543, 10.1523/JNEUROSCI.5019-07.2008
Schratt, 2009, Fine-tuning neural gene expression with microRNAs, Curr. Opin. Neurobiol., 19, 213, 10.1016/j.conb.2009.05.015
Schratt, 2006, A brain-specific microRNA regulates dendritic spine development, Nature, 439, 283, 10.1038/nature04367
Schutt, 2009, Fragile X mental retardation protein regulates the levels of scaffold proteins and glutamate receptors in postsynaptic densities, J. Biol. Chem., 284, 25479, 10.1074/jbc.M109.042663
Siegel, 2009, A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis, Nat. Cell Biol., 11, 705, 10.1038/ncb1876
Stefani, 2004, Fragile X mental retardation protein is associated with translating polyribosomes in neuronal cells, J. Neurosci., 24, 7272, 10.1523/JNEUROSCI.2306-04.2004
Todd, 2003, The fragile X mental retardation protein is required for type-I metabotropic glutamate receptor-dependent translation of PSD-95, Proc. Natl. Acad. Sci. USA, 100, 14374, 10.1073/pnas.2336265100
Ule, 2005, CLIP: a method for identifying protein-RNA interaction sites in living cells, Methods, 37, 376, 10.1016/j.ymeth.2005.07.018
Vanderklish, 2002, Dendritic spines elongate after stimulation of group 1 metabotropic glutamate receptors in cultured hippocampal neurons, Proc. Natl. Acad. Sci. USA, 99, 1639, 10.1073/pnas.032681099
Vasudevan, 2007, Switching from repression to activation: microRNAs can up-regulate translation, Science, 318, 1931, 10.1126/science.1149460
Xu, 2008, Molecular dissociation of the role of PSD-95 in regulating synaptic strength and LTD, Neuron, 57, 248, 10.1016/j.neuron.2007.11.027
