Retention and tolerance of autoreactive CD4+ recent thymic emigrants in the liver
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Gallegos, 2006, Central tolerance: good but imperfect, Immunol Rev, 209, 290, 10.1111/j.0105-2896.2006.00348.x
Stritesky, 2012, Selection of self-reactive T cells in the thymus, Annu Rev Immunol, 30, 95, 10.1146/annurev-immunol-020711-075035
Mueller, 2010, Mechanisms maintaining peripheral tolerance, Nat Immunol, 11, 21, 10.1038/ni.1817
Mathis, 2009, Aire Annu Rev Immunol, 27, 287, 10.1146/annurev.immunol.25.022106.141532
Anderson, 2002, Projection of an immunological self shadow within the thymus by the aire protein, Science, 298, 1395, 10.1126/science.1075958
Liston, 2004, Gene dosage–limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity, J Exp Med, 200, 1015, 10.1084/jem.20040581
Kurts, 1997, Class I-restricted cross-presentation of exogenous self-antigens leads to deletion of autoreactive CD8(+) T cells, J Exp Med, 186, 239, 10.1084/jem.186.2.239
Morgan, 1999, Ontogeny of T cell tolerance to peripherally expressed antigens, Proc Natl Acad Sci U S A, 96, 3854, 10.1073/pnas.96.7.3854
Belz, 2002, The CD8alpha(+) dendritic cell is responsible for inducing peripheral self-tolerance to tissue-associated antigens, J Exp Med, 196, 1099, 10.1084/jem.20020861
Lee, 2007, Peripheral antigen display by lymph node stroma promotes T cell tolerance to intestinal self, Nat Immunol, 8, 181, 10.1038/ni1427
Metzger, 2011, Control of central and peripheral tolerance by Aire, Immunol Rev, 241, 89, 10.1111/j.1600-065X.2011.01008.x
Thangavelu, 2011, Programmed death-1 is required for systemic self-tolerance in newly generated T cells during the establishment of immune homeostasis, J Autoimmun, 36, 301, 10.1016/j.jaut.2011.02.009
Houston, 2009, MHC drives TCR repertoire shaping, but not maturation, in recent thymic emigrants, J Immunol, 183, 7244, 10.4049/jimmunol.0902313
Fink, 2013, The biology of recent thymic emigrants, Annu Rev Immunol, 31, 31, 10.1146/annurev-immunol-032712-100010
Mabarrack, 2008, Recent thymic origin, differentiation, and turnover of regulatory T cells, J Leukoc Biol, 84, 1287, 10.1189/jlb.0308201
Berkley, 2014, Cutting edge: CD8+ recent thymic emigrants exhibit increased responses to low-affinity ligands and improved access to peripheral sites of inflammation, J Immunol, 193, 3262, 10.4049/jimmunol.1401870
Teng, 2011, The molecular signature underlying the thymic migration and maturation of TCRalphabeta+ CD4+ CD8 thymocytes, PLoS One, 6, 10.1371/journal.pone.0025567
Jin, 2008, Characterization of the in vivo dynamics of medullary CD4+CD8− thymocyte development, J Immunol, 180, 2256, 10.4049/jimmunol.180.4.2256
Starr, 2003, Positive and negative selection of T cells, Annu Rev Immunol, 21, 139, 10.1146/annurev.immunol.21.120601.141107
Li, 2007, Developmental pathway of CD4+CD8− medullary thymocytes during mouse ontogeny and its defect in Aire−/− mice, Proc Natl Acad Sci U S A, 104, 18175, 10.1073/pnas.0708884104
Xu, 2013, Maturation and emigration of single-positive thymocytes, Clin Dev Immunol, 2013, 282870, 10.1155/2013/282870
Kim, 2011, The requirements for natural Th17 cell development are distinct from those of conventional Th17 cells, J Exp Med, 208, 2201, 10.1084/jem.20110680
Bai, 2007, Kruppel-like factor 2 controls T cell trafficking by activating L-selectin (CD62L) and sphingosine-1-phosphate receptor 1 transcription, J Immunol, 178, 7632, 10.4049/jimmunol.178.12.7632
Fontenot, 2005, Regulatory T cell lineage specification by the forkhead transcription factor foxp3, Immunity, 22, 329, 10.1016/j.immuni.2005.01.016
Vondenhoff, 2009, LTbetaR signaling induces cytokine expression and up-regulates lymphangiogenic factors in lymph node anlagen, J Immunol, 182, 5439, 10.4049/jimmunol.0801165
Onder, 2013, Endothelial cell-specific lymphotoxin-beta receptor signaling is critical for lymph node and high endothelial venule formation, J Exp Med, 210, 465, 10.1084/jem.20121462
Boursalian, 2004, Continued maturation of thymic emigrants in the periphery, Nat Immunol, 5, 418, 10.1038/ni1049
Oo, 2012, Regulatory T cells and autoimmune hepatitis: defective cells or a hostile environment?, J Hepatol, 57, 6, 10.1016/j.jhep.2012.04.005
Kurts, 1996, Constitutive class I-restricted exogenous presentation of self antigens in vivo, J Exp Med, 184, 923, 10.1084/jem.184.3.923
Barnden, 1994, Peptide antagonists that promote positive selection are inefficient at T cell activation and thymocyte deletion, Eur J Immunol, 24, 2452, 10.1002/eji.1830241029
Anderson, 2005, The cellular mechanism of Aire control of T cell tolerance, Immunity, 23, 227, 10.1016/j.immuni.2005.07.005
Gallegos, 2004, Central tolerance to tissue-specific antigens mediated by direct and indirect antigen presentation, J Exp Med, 200, 1039, 10.1084/jem.20041457
Paiva, 2013, Recent thymic emigrants are the preferential precursors of regulatory T cells differentiated in the periphery, Proc Natl Acad Sci U S A, 110, 6494, 10.1073/pnas.1221955110
Crispe, 2009, The liver as a lymphoid organ, Annu Rev Immunol, 27, 147, 10.1146/annurev.immunol.021908.132629
Martinez, 2012, Arthritogenic self-reactive CD4+ T cells acquire an FR4hiCD73hi anergic state in the presence of Foxp3+ regulatory T cells, J Immunol, 188, 170, 10.4049/jimmunol.1101311
Daley, 2013, Helios marks strongly autoreactive CD4+ T cells in two major waves of thymic deletion distinguished by induction of PD-1 or NF-kappaB, J Exp Med, 210, 269, 10.1084/jem.20121458
Erhardt, 2007, IL-10, regulatory T cells, and Kupffer cells mediate tolerance in concanavalin A-induced liver injury in mice, Hepatology, 45, 475, 10.1002/hep.21498
Wang, 2011, Signal transducer and activator of transcription 3 in liver diseases: a novel therapeutic target, Int J Biol Sci, 7, 536, 10.7150/ijbs.7.536
Shevach, 2014, tTregs, pTregs, and iTregs: similarities and differences, Immunol Rev, 259, 88, 10.1111/imr.12160
Benseler, 2011, Hepatocyte entry leads to degradation of autoreactive CD8 T cells, Proc Natl Acad Sci U S A, 108, 16735, 10.1073/pnas.1112251108
Sawa, 2009, Hepatic interleukin-7 expression regulates T cell responses, Immunity, 30, 447, 10.1016/j.immuni.2009.01.007
Surh, 2008, Homeostasis of naive and memory T cells, Immunity, 29, 848, 10.1016/j.immuni.2008.11.002
Takada, 2009, Naive T cell homeostasis: from awareness of space to a sense of place, Nat Rev Immunol, 9, 823, 10.1038/nri2657
Stefanova, 2002, Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes, Nature, 420, 429, 10.1038/nature01146
Gardner, 2008, Deletional tolerance mediated by extrathymic Aire-expressing cells, Science, 321, 843, 10.1126/science.1159407
Klamp, 2006, Expression profiling of autoimmune regulator AIRE mRNA in a comprehensive set of human normal and neoplastic tissues, Immunol Lett, 106, 172, 10.1016/j.imlet.2006.06.006
Poliani, 2010, Human peripheral lymphoid tissues contain autoimmune regulator-expressing dendritic cells, Am J Pathol, 176, 1104, 10.2353/ajpath.2010.090956
Gardner, 2013, Extrathymic Aire-expressing cells are a distinct bone marrow-derived population that induce functional inactivation of CD4(+) T cells, Immunity, 39, 560, 10.1016/j.immuni.2013.08.005
Fletcher, 2010, Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions, J Exp Med, 207, 689, 10.1084/jem.20092642
Halonen, 2001, Subcellular location and expression pattern of autoimmune regulator (Aire), the mouse orthologue for human gene defective in autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED), J Histochem Cytochem, 49, 197, 10.1177/002215540104900207
Thomson, 2010, Antigen-presenting cell function in the tolerogenic liver environment, Nat Rev Immunol, 10, 753, 10.1038/nri2858
Tang, 2013, IL-7 licenses activation of human liver intrasinusoidal mucosal-associated invariant T cells, J Immunol, 190, 3142, 10.4049/jimmunol.1203218
Hou, 2013, Early IL-17 production by intrahepatic T cells is important for adaptive immune responses in viral hepatitis, J Immunol, 190, 621, 10.4049/jimmunol.1201970
Adamson, 2004, A comparative study of mRNA and protein expression of the autoimmune regulator gene (Aire) in embryonic and adult murine tissues, J Pathol, 202, 180, 10.1002/path.1493
Holt, 2009, Liver myofibroblasts regulate infiltration and positioning of lymphocytes in human liver, Gastroenterology, 136, 705, 10.1053/j.gastro.2008.10.020
Curbishley, 2005, CXCR 3 activation promotes lymphocyte transendothelial migration across human hepatic endothelium under fluid flow, Am J Pathol, 167, 887, 10.1016/S0002-9440(10)62060-3
Schrage, 2008, Enhanced T cell transmigration across the murine liver sinusoidal endothelium is mediated by transcytosis and surface presentation of chemokines, Hepatology, 48, 1262, 10.1002/hep.22443
Staton, 2006, CD8+ recent thymic emigrants home to and efficiently repopulate the small intestine epithelium, Nat Immunol, 7, 482, 10.1038/ni1319
Coles, 2012, Alemtuzumab for patients with relapsing multiple sclerosis after disease-modifying therapy: a randomised controlled phase 3 trial, Lancet, 380, 1829, 10.1016/S0140-6736(12)61768-1
Coles, 2008, Alemtuzumab vs. interferon beta-1a in early multiple sclerosis, N Engl J Med, 359, 1786, 10.1056/NEJMoa0802670
Cohen, 2012, Alemtuzumab versus interferon beta 1a as first-line treatment for patients with relapsing-remitting multiple sclerosis: a randomised controlled phase 3 trial, Lancet, 380, 1819, 10.1016/S0140-6736(12)61769-3