Responses of Small Mammals to Habitat Fragmentation: Epidemiological Considerations for Rodent-Borne Hantaviruses in the Americas

EcoHealth - Tập 11 - Trang 526-533 - 2014
André V. Rubio1, Rafael Ávila-Flores2, Gerardo Suzán1
1Departamento de Etología, Fauna Silvestre y Animales de Laboratorio, Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autónoma de México, Mexico, Mexico
2División Académica de Ciencias Biológicas, Universidad Juárez Autónoma de Tabasco, Villahermosa, Mexico

Tóm tắt

Rodent-borne hantaviruses are a group of zoonotic agents that cause hemorrhagic fever in humans. The transmission of hantaviruses among rodent hosts may be higher with the increase of reservoir host abundance in a given area (density-dependent transmission) and with the decrease of small mammal diversity (dilution effect phenomenon). These population and community parameters may be modified by habitat fragmentation; however, studies that focus on fragmentation and its effect on hantavirus infection risk are scarce. To further understanding of this issue, we assessed some population and community responses of rodents that may increase the risk for hantavirus transmission among wildlife hosts in the Americas. We conducted a meta-analysis of published studies to assess the responses of small mammals to fragmentation of native habitats, relative to patch size. Our analyses included five countries and 14 case studies for abundance of reservoir hosts (8 species) and 15 case studies for species richness. We found that a reduction of patch area due to habitat fragmentation is associated with increased reservoir host abundances and decreased small mammal richness, which is mainly due to the loss of non-host small mammals. According to these results, habitat fragmentation in the Americas should be considered as an epidemiological risk factor for hantavirus transmission to humans. These findings are important to assess potential risk of infection when fragmentation of native habitats occurs.

Tài liệu tham khảo

Abbott KD, Ksiazek TG, and Mills JN (1999) Long-term hantavirus persistence in rodent populations in central Arizona. Emerging Infectious Diseases 5:102-112 Arnqvist G, and Wooster D (1995) Meta-analysis: synthesizing research findings in ecology and evolution. Trends in Ecology & Evolution 10:236-240 Begon M, Bennett M, Bowers R, French N, Hazel S, and Turner J (2002) A clarification of transmission terms in host-microparasite models: numbers, densities and areas. Epidemiology and Infection 129:147-153 Blasdell K, Cosson JF, Chaval Y, Herbreteau V, Douangboupha B, Jittapalapong S, et al. (2011) Rodent-Borne Hantaviruses in Cambodia, Lao PDR, and Thailand. EcoHealth 8:432-443 Boone JD, Otteson EW, McGwire KC, Villard P, Rowe JE, and St Jeor SC (1998) Ecology and demographics of hantavirus infections in rodent populations in the Walker River Basin of Nevada and California. American Journal of Tropical Medicine and Hygiene 59:445-451 Brady MJ, McAlpine CA, Possingham HP, Miller CJ, and Baxter GS (2011) Matrix is important for mammals in landscapes with small amounts of native forest habitat. Landscape Ecology 26:617-628 Brooks TM, Mittermeier RA, Mittermeier CG, Da Fonseca GA, Rylands AB, Konstant WR, et al. (2002) Habitat loss and extinction in the hotspots of biodiversity. Conservation Biology 16:909-923 Carver S, Kuenzi A, Bagamian KH, Mills JN, Rollin PE, Zanto SN, et al. (2011a) A temporal dilution effect: hantavirus infection in deer mice and the intermittent presence of voles in Montana. Oecologia 166:713-721 Carver S, Trueax JT, Douglass R, and Kuenzi A (2011b) Delayed density-dependent prevalence of Sin Nombre virus infection in deer mice (Peromyscus maniculatus) in central and western Montana. Journal of Wildlife Diseases 47:56-63 Clay CA, Lehmer EM, Jeor SS, and Dearing MD (2009) Sin Nombre Virus and Rodent Species Diversity: A Test of the Dilution and Amplification Hypotheses. Plos One 4:e6467 Cruz CD, Forshey BM, Vallejo E, Agudo R, Vargas J, Blazes DL, et al. (2012) Novel strain of Andes virus associated with fatal human infection, central Bolivia. Emerging Infectious Diseases 18:750-757 Debinski DM (2006) Forest fragmentation and matrix effects: the matrix does matter. Journal of Biogeography 33:1791-1792 Dearing MD, and Dizney L (2010) Ecology of hantavirus in a changing world. Annals of the New York Academy of Sciences 1195:99-112 Dizney LJ, and Ruedas LA (2009) Increased Host Species Diversity and Decreased Prevalence of Sin Nombre Virus. Emerging Infectious Diseases 15:1012-1018 Dobson AP, and Hudson PJ. (1995) Microparasites: Observed patterns in wild animal populations. In: Ecology of infectious diseases in natural populations, Grenfell BT, Dobson A (editors), Cambridge, UK: Cambridge University Press, pp 52–89 Douglass RJ, Wilson T, Semmens WJ, Zanto SN, Bond CW, Van Horn RC, et al. (2001) Longitudinal studies of Sin Nombre virus in deer mouse-dominated ecosystems of Montana. American Journal of Tropical Medicine and Hygiene 65:33-41 Escutenaire S, Thomas I, Clement J, Verhagen R, Chalon P, and Pastoret PP (1997) Hantavirus epidemiology in red bank voles (Clethrionomys glareolus). Annales de Medecine Veterinaire 141:471-476 Ewers RM, and Didham RK (2006) Confounding factors in the detection of species responses to habitat fragmentation. Biological Reviews 81:117-142 Fahrig L (2003) Effects of habitat fragmentation on biodiversity. Annual Review of Ecology Evolution and Systematics 34:487-515 Guo W-P, Lin X-D, Wang W, Tian J-H, Cong M-L, Zhang H-L, et al. (2013) Phylogeny and origins of hantaviruses harbored by bats, insectivores, and rodents. Plos Pathogens 9:e1003159 Gurevitch J, and Hedges VL (2001) Meta-analysis: combining the results of independent experiments. In: Design and analysis of ecological experiments, Scheiner SM, Gurevitch J (editors), New York: Oxford University Press, pp 347–369 Hedges LV, and Olkin I (1985) Statistical methods for meta-analysis. Boston: Academic Press Hjelle B, and Torres-Pérez F (2010) Hantaviruses in the Americas and their role as emerging pathogens. Viruses 2:2559-2586 Jonsson CB, Moraes Figueiredo LT, and Vapalahti O (2010) A Global Perspective on Hantavirus Ecology, Epidemiology, and Disease. Clinical Microbiology Reviews 23:412-441 Kariwa H, Yoshida H, Sanchez-Hernandez C, de Lourdes Romero-Almaraz M, Alberto Almazan-Catalan J, Ramos C, et al. (2012) Genetic diversity of hantaviruses in Mexico: Identification of three novel hantaviruses from Neotominae rodents. Virus Research 163:486-494 Keesing F, Holt RD, and Ostfeld RS (2006) Effects of species diversity on disease risk. Ecology Letters 9:485-498 Langlois JP, Fahrig L, Merriam G, and Artsob H (2001) Landscape structure influences continental distribution of hantavirus in deer mice. Landscape Ecology 16:255-266 Lee H, Bark D, Baek L, Choi K, Whang Y, and Woo M (1980) Korean hemorrhagic fever patients in urban areas of Seoul. Korean Journal of Virology 10:1-6 Lobos G, Ferres M, and Palma RE (2005) Presencia de los géneros invasores Mus y Rattus en áreas naturales de Chile: un riesgo ambiental y epidemiológico. Revista Chilena de Historia Natural 78:113-124 Mackelprang R, Dearing MD, and St Jeor S (2001) High prevalence of Sin Nombre virus in rodent populations, central Utah: a consequence of human disturbance? Emerging Infectious Diseases 7:480-482 Madhav NK, Wagoner KD, Douglass RJ, and Mills JN (2007) Delayed density-dependent prevalence of Sin Nombre virus antibody in Montana deer mice (Peromyscus maniculatus) and implications for human disease risk. Vector-Borne and Zoonotic Diseases 7:353-364 Matheus S, Lavergne A, de Thoisy B, Dussart P, and Lacoste V (2012) Complete genome sequence of a novel hantavirus variant of Rio Mamore virus, Maripa virus, from French Guiana. Journal of Virology 86:5399-5399 Markl J, Schleuning M, Forget P, Jordano P, Lambert J, Traveset A, et al. (2012) Meta-analysis of the effects of human disturbance on seed dispersal by animals. Conservation Biology 26:1072-1081 Mills JN, Ksiazek TG, Peters C, and Childs JE (1999) Long-term studies of hantavirus reservoir populations in the southwestern United States: a synthesis. Emerging Infectious Diseases 5:135-142 Myers SS, Gaffikin L, Golden CD, Ostfeld RS, Redford KH, Ricketts TH, et al. (2013) Human health impacts of ecosystem alteration. Proceedings of the National Academy of Sciences 110:18753-18760 Niklasson B, Hornfeldt B, Lundkvist A, Bjorsten S, and Leduc J (1995) Temporal dynamics of Puumala virus antibody prevalence in voles and of nephropathia epidemica incidence in humans. The American Journal of Tropical Medicine and Hygiene 53:134-140 Olsson GE, White N, Ahlm C, Elgh F, Verlemyr AC, Juto P, et al. (2002) Demographic factors associated with hantavirus infection in bank voles (Clethrionomys glareolus). Emerging Infectious Diseases 8:924-929 Ostfeld RS, and Keesing F (2012) Effects of Host Diversity on Infectious Disease. Annual Review of Ecology, Evolution, and Systematics 43:157-182 Pardini R (2004) Effects of forest fragmentation on small mammals in an Atlantic Forest landscape. Biodiversity & Conservation 13:2567-2586 Prugh LR, Hodges KE, Sinclair AR, and Brashares JS (2008) Effect of habitat area and isolation on fragmented animal populations. Proceedings of the National Academy of Sciences 105:20770-20775 Rosenberg MS, Adams DC, and Gurevitch J (2000) MetaWin: statistical software for meta-analysis. Sunderland, Massachusetts: Sinauer Associates Rosenthal R (1979) The file drawer problem and tolerance for null results. Psychological Bulletin 86:638-641 Ruedas LA, Salazar-Bravo J, Tinnin DS, Armién B, Cáceres L, García A, et al. (2004) Community ecology of small mammal populations in Panama following an outbreak of Hantavirus pulmonary syndrome. Journal of Vector Ecology 29:177-191 Suzán G, Armien A, Mills JN, Marce E, Ceballos G, Avila M, et al. (2008) Epidemiological considerations of rodent community composition in fragmented landscapes in Panama. Journal of Mammalogy 89:684-690 Suzán G, Marce E, Giermakowski JT, Mills JN, Ceballos G, Ostfeld RS, et al. (2009) Experimental Evidence for Reduced Rodent Diversity Causing Increased Hantavirus Prevalence. Plos One 4:e5461 Suzán G, Esponda F, Carrasco-Hernández R, and Aguirre AA (2012) Habitat Fragmentation and Infectious Disease Ecology. In: New Directions in Conservation Medicine: Applied Cases of Ecological Health, Aguirre, AA, Ostfeld RS, Daszak (editors), New York: Oxford University Press, pp 135-150 Tersago K, Schreurs A, Linard C, Verhagen R, Van Dongen S, and Leirs H (2008) Population, environmental, and community effects on local bank vole (Myodes glareolus) Puumala virus infection in an area with low human incidence. Vector-Borne and Zoonotic Diseases 8:235-244 Vargas RR, Fontúrbel FE, Bonacorso E, and Simonetti JA (2012) Variation in reproductive life-history traits of birds in fragmented habitats: a review and meta-analysis. Bird Conservation International 22:462-467 Voutilainen L, Savola S, Kallio ER, Laakkonen J, Vaheri A, Vapalahti O, et al. (2012) Environmental Change and Disease Dynamics: Effects of Intensive Forest Management on Puumala Hantavirus Infection in Boreal Bank Vole Populations. Plos One 7:e39452 Wang H, Yoshimatsu K, Ebihara H, Ogino M, Araki K, Kariwa H, et al. (2000) Genetic Diversity of Hantaviruses Isolated in China and Characterization of Novel Hantaviruses Isolated from Niviventer confucianus and Rattus rattus. Virology 278:332-345 Yahnke CJ, Meserve PL, Ksiazek TG, and Mills JN (2001) Patterns of infection with Laguna Negra virus in wild populations of Calomys laucha in the central Paraguayan chaco. American Journal of Tropical Medicine and Hygiene 65:768-776 Yates TL, Mills JN, Parmenter CA, Ksiazek TG, Parmenter RR, Vande Castle JR, et al. (2002) The ecology and evolutionary history of an emergent disease: Hantavirus pulmonary syndrome. Bioscience 52:989-998 Zhang Y, Yuan J, Yang X, Zhou J, Yang W, Peng C, et al. (2011) A novel hantavirus detected in Yunnan red-backed vole (Eothenomys miletus) in China. Journal of General Virology 92:1454-1457 Zeitz PS, Butler JC, Cheek JE, Samuel MC, Childs JE, Shands LA, et al. (1995) A case-control study of hantavirus pulmonary syndrome during an outbreak in the southwestern United States. Journal of Infectious Diseases 171:864-870