Respiratory syncytial virus fusion inhibitors. Part 6: An examination of the effect of structural variation of the benzimidazol-2-one heterocycle moiety

Bioorganic & Medicinal Chemistry Letters - Tập 17 - Trang 4784-4790 - 2007
Keith D. Combrink1, H. Belgin Gulgeze1, Jan W. Thuring1, Kuo-Long Yu1, Rita L. Civiello1, Yi Zhang1, Bradley C. Pearce1, Zhiwei Yin1, David R. Langley2, Kathleen F. Kadow3, Christopher W. Cianci3, Zhufang Li3, Junius Clarke3, Eugene V. Genovesi3, Ivette Medina3, Lucinda Lamb3, Zheng Yang4, Lisa Zadjura4, Mark Krystal3, Nicholas A. Meanwell1
1Department of Chemistry, Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492, USA
2Department of Computer-Aided Drug Design, Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492, USA
3Department of Virology, Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492, USA
4Department of Metabolism and Pharmacokinetics, Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492, USA

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