Resolution of chronic hepatitis Delta after 1 year of combined therapy with pegylated interferon, tenofovir and emtricitabine

Journal of Clinical Virology - Tập 47 - Trang 97-99 - 2010
Wael Mansour1,2, Alexandra Ducancelle1,2, Frédéric Le Gal3, Hélène Le Guillou-Guillemette1,2, Pierre Abgueguen4, Adeline Pivert1,2, Paul Calès1,5, Emmanuel Gordien3, Françoise Lunel1,2
1Laboratoire HIFIH UPRES EA 3859, Faculté de Médecine d’Angers, France
2Laboratoire de virologie, CHU Angers, 4, rue Larrey 49933, Angers cedex 9, France
3Laboratoire de virologie, CH&U Avicenne, associé au CNR des hépatites B, C et Delta, 125, boulevard de Stalingrad 93009 Bobigny cedex, France
4Service des Maladies Infectieuses et Tropicales, CHU, Angers, 4, rue Larrey 49933, Angers cedex 9, France
5Service d’Hépato-Gastroentérologie, CHU, Angers, 4, rue Larrey 49933, Angers cedex 9, France

Tài liệu tham khảo

Rizzetto, 1977, Immunofluorescence detection of a new antigen-antibody system delta/anti-delta associated to the hepatitis B virus in the liver and the serum of HBs-Ag carriers, Gut, 18, 997, 10.1136/gut.18.12.997 Hsieh, 2006, Natural course and treatment of hepatitis D virus infection, J Formos Med Assoc, 105, 869, 10.1016/S0929-6646(09)60172-8 Farci, 2003, Delta hepatitis: an update, J Hepatol, 39, S212, 10.1016/S0168-8278(03)00331-3 Castelnau, 2006, Efficacy of peginterferon alpha-2b in chronic hepatitis delta: relevance of quantitative RT-PCR for follow-up, Hepatology, 44, 728, 10.1002/hep.21325 Le Gal, 2005, Quantification of hepatitis delta virus RNA in serum by consensus real-time PCR indicates different patterns of virological response to interferon therapy in chronically infected patients, J Clin Microbiol, 43, 2363, 10.1128/JCM.43.5.2363-2369.2005 Radjef, 2004, Molecular phylogenetic analyses indicate a wide and ancient radiation of African hepatitis delta virus, suggesting a Deltavirus genus of at least seven major clades, J Virol, 78, 2537, 10.1128/JVI.78.5.2537-2544.2004 Williams, 2009, Hepatitis delta virus proteins repress hepatitis B virus enhancers and activate the alpha/beta interferon-inducible MxA gene, J Gen Virol, 90, 2759, 10.1099/vir.0.011239-0 Bozdayi, 2004, Molecular epidemiology of hepatitis B, C and D viruses in Turkish patients, Arch Virol, 149, 2115, 10.1007/s00705-004-0363-2 Farci, 2004, Long-term benefit of interferon alpha therapy of chronic hepatitis D: regression of advanced hepatic fibrosis, Gastroenterology, 126, 1740, 10.1053/j.gastro.2004.03.017 Gozlan, 2009, Complete cure of HBV-HDV co-infection after 24 weeks of combination therapy with pegylated interferon and ribavirin in a patient co-infected with HBV/HCV/HDV/HIV, J Hepatol, 50, 432, 10.1016/j.jhep.2008.05.029 Van Bömmel, 2004, Comparison of adefovir and tenofovir in the treatment of lamivudine-resistant hepatitis B virus infection, Hepatology, 40, 1421, 10.1002/hep.20464 Wursthorn, 2006, Peginterferon alpha-2b plus adefovir induce strong cccDNA decline and HBsAg reduction in patients with chronic hepatitis B, Hepatology, 44, 675, 10.1002/hep.21282