Reprint of: A parallel randomized trial on the effect of a healthful diet on inflammageing and its consequences in European elderly people: Design of the NU-AGE dietary intervention study

AFSSA, CNERNA-CNRS, 2001 Alles, 2012, Dietary patterns: a novel approach to examine the link between nutrition and cognitive function in older individuals, Nutr. Res. Rev., 25, 207, 10.1017/S0954422412000133 Alonso, 2006, Monounsaturated fatty acids, olive oil and blood pressure: epidemiological, clinical and experimental evidence, Public Health Nutr., 9, 251, 10.1079/PHN2005836 Andres, 2009, Update of oral vitamin B12, Ann. Endocrinol. (Paris), 70, 455, 10.1016/j.ando.2009.07.001 Babio, 2009, Adherence to the Mediterranean diet and risk of metabolic syndrome and its components, Nutr. Metab. Cardiovasc. Dis., 19, 563, 10.1016/j.numecd.2008.10.007 Bingham, 1994, Comparison of dietary assessment methods in nutritional epidemiology: weighed records v. 24h recalls, food-frequency questionnaires and estimated-diet records, Br. J. Nutr., 72, 619, 10.1079/BJN19940064 Bischoff-Ferrari, 2009, Fall prevention with supplemental and active forms of vitamin D: a meta-analysis of randomised controlled trials, BMJ, 339, b3692, 10.1136/bmj.b3692 Bischoff-Ferrari, 2009, Dietary calcium and serum 25-hydroxyvitamin D status in relation to BMD among U.S. adults, J. Bone Miner. Res., 24, 935, 10.1359/jbmr.081242 Bouwens, 2009, Fish-oil supplementation induces antiinflammatory gene expression profiles in human blood mononuclear cells, Am. J. Clin. Nutr., 90, 415, 10.3945/ajcn.2009.27680 Calder, 2008, Polyunsaturated fatty acids, inflammatory processes and inflammatory bowel diseases, Mol. Nutr. Food Res., 52, 885, 10.1002/mnfr.200700289 Carriere, 2007, Nutrient intake in an elderly population in southern France (POLANUT): deficiency in some vitamins, minerals and omega-3 PUFA, Int. J. Vitam. Nutr. Res., 77, 57, 10.1024/0300-9831.77.1.57 Cavelaars, 2010, Prioritizing micronutrients for the purpose of reviewing their requirements: a protocol developed by EURRECA, Eur. J. Clin. Nutr., 64, S19, 10.1038/ejcn.2010.57 Cevenini, 2013, Inflamm-ageing, Curr. Opin. Clin. Nutr. Metab. Care, 16, 14, 10.1097/MCO.0b013e32835ada13 Commission of the European Communities, 1993 Coulston, 2008 Dawson-Hughes, 1997, Effect of calcium and vitamin D supplementation on bone density in men and women 65 years of age or older, N. Engl. J. Med., 337, 670, 10.1056/NEJM199709043371003 de Lorgeril, 1994, Mediterranean alpha-linolenic acid-rich diet in secondary prevention of coronary heart disease, Lancet, 343, 1454, 10.1016/S0140-6736(94)92580-1 de Munter, 2007, Whole grain, bran, and germ intake and risk of type 2 diabetes: a prospective cohort study and systematic review, PLoS Med., 4, e261, 10.1371/journal.pmed.0040261 Department of Health, 1991 Elmadfa, 2009, Nutritional status in Europe: methods and results, Nutr. Rev., 67, S130L 134 Estruch, 2006, Effects of a Mediterranean-style diet on cardiovascular risk factors: a randomized trial, Ann. Intern. Med., 145, 1, 10.7326/0003-4819-145-1-200607040-00004 Estruch, 2013, Primary prevention of cardiovascular disease with a Mediterranean diet, N. Engl. J. Med., 368, 1279, 10.1056/NEJMoa1200303 Eurostat, 2011, EUROPOP2010 – Convergence scenario, national level – assumptions Food and Nutrition Council, 1992 Franceschi, 2007, Inflammaging as a major characteristic of old people: can it be prevented or cured?, Nutr. Rev., 65, S173, 10.1301/nr.2007.dec.S173-S176 Franceschi, 2000, Inflamm-aging: an evolutionary perspective on immunosenescence, Ann. N.Y. Acad. Sci., 908, 244, 10.1111/j.1749-6632.2000.tb06651.x Franceschi, 2007, Inflammaging and anti-inflammaging: a systemic perspective on aging and longevity emerged from studies in humans, Mech. Ageing Dev., 128, 92, 10.1016/j.mad.2006.11.016 Franceschi, 2000, The network and the remodeling theories of aging: historical background and new perspectives, Exp. Gerontol., 35, 879, 10.1016/S0531-5565(00)00172-8 Fried, 2001, Frailty in older adults: evidence for a phenotype, J. Gerontol. A Biol. Sci. Med. Sci., 56, M146, 10.1093/gerona/56.3.M146 Gaesser, 2007, Carbohydrate quantity and quality in relation to body mass index, J. Am. Diet. Assoc., 107, 1768, 10.1016/j.jada.2007.07.011 Hamer, 2007, Intake of fruit, vegetables, and antioxidants and risk of type 2 diabetes: systematic review and meta-analysis, J. Hypertens., 25, 2361, 10.1097/HJH.0b013e3282efc214 Health Council of the Netherlands, 2000, 180 Health Council of the Netherlands, 2001 Health Council of the Netherlands, 2003 Health council of the Netherlands, 2006 Health council of the Netherlands, 2006 Health Council of the Netherlands, 2008, 172 Hin, 2006, Clinical relevance of low serum vitamin B12 concentrations in older people: the Banbury B12 study, Age Ageing, 35, 416, 10.1093/ageing/afl033 Huijbregts, 1997, Dietary pattern and 20 year mortality in elderly men in Finland, Italy, and The Netherlands: longitudinal cohort study, BMJ, 315, 13, 10.1136/bmj.315.7099.13 Institute of Medicine of the National Academies, 2006 Istituto Nazionale di Ricerca per gli Alimenti e la Nutrizione, 2003 Jacobs, 2003, Nutrients, foods, and dietary patterns as exposures in research: a framework for food synergy, Am. J. Clin. Nutr., 78, 508S, 10.1093/ajcn/78.3.508S Jacques, 2001, Are dietary patterns useful for understanding the role of diet in chronic disease?, Am. J. Clin. Nutr., 73, 1, 10.1093/ajcn/73.1.1 Jarosz, 2008 Kastorini, 2011, The effect of Mediterranean diet on metabolic syndrome and its components: a meta-analysis of 50 studies and 534,906 individuals, J. Am. Coll. Cardiol., 57, 1299, 10.1016/j.jacc.2010.09.073 Kraguljac, 2009, Efficacy of omega-3 fatty acids in mood disorders – a systematic review and metaanalysis, Psychopharmacol. Bull., 42, 39 Martinez-Gonzalez, 2010, Cohort profile: design and methods of the PREDIMED study, Int. J. Epidemiol., 41, 377, 10.1093/ije/dyq250 McNaughton, 2012, Diet quality is associated with all-cause mortality in adults aged 65 years and older, J. Nutr., 142, 320, 10.3945/jn.111.148692 Mellen, 2008, Whole grain intake and cardiovascular disease: a meta-analysis, Nutr. Metab. Cardiovasc. Dis., 18, 283, 10.1016/j.numecd.2006.12.008 Miller, 2002 Ministère du Travail, 2011 Paddon-Jones, 2009, Dietary protein recommendations and the prevention of sarcopenia, Curr. Opin. Clin. Nutr. Metab. Care, 12, 86, 10.1097/MCO.0b013e32831cef8b Pan, 2009, Meta-analysis of the effects of flaxseed interventions on blood lipids, Am. J. Clin. Nutr., 90, 288, 10.3945/ajcn.2009.27469 Panunzio, 2011, Randomized, controlled nutrition education trial promotes a Mediterranean diet and improves anthropometric, dietary, and metabolic parameters in adults, Ann. Ig., 23, 13 Patterson, 1994, Diet quality index: capturing a multidimensional behavior, J. Am. Diet. Assoc., 94, 57, 10.1016/0002-8223(94)92042-7 Peregrin, 2008, Getting to know the modified MyPyramid for Older Adults, J. Am. Diet. Assoc., 108, 937, 10.1016/j.jada.2008.04.006 Prochaska, 1982, Transtheoretical therapy: toward a more integrative model of change, Psychother. Theory Res. Pract., 19, 276, 10.1037/h0088437 Richard, 2011, Effect of the Mediterranean diet with and without weight loss on cardiovascular risk factors in men with the metabolic syndrome, Nutr. Metab. Cardiovasc. Dis., 21, 628, 10.1016/j.numecd.2010.01.012 Richard, 2013, Effect of the Mediterranean diet with and without weight loss on markers of inflammation in men with metabolic syndrome, Obesity (Silver Spring, MD), 21, 51, 10.1002/oby.20239 Rodriguez Sangrador, 2008, The contribution of diet and sun exposure to the nutritional status of vitamin D in elderly Spanish women: the five countries study (OPTIFORD Project), Nutr. Hosp., 23, 567 Salas-Salvado, 2008, Components of the Mediterranean-type food pattern and serum inflammatory markers among patients at high risk for cardiovascular disease, Eur. J. Clin. Nutr., 62, 651, 10.1038/sj.ejcn.1602762 Santoro, A., Pini, E., Scurti, M., Palmas, G., Berendsen, A., Brzozowska, B., Pietruszka, B., Sczenziska, A., Cano, N., Meunier, N., de Groot, C.P.M.H., Feskens, E., Fairweather-Tait, S., Salvioli, S., Capri, M., Brigidi, P., Franceschi, C. Combating inflammageing through a Mediterranean whole diet approach: the NU-AGE project's conceptual framework and design. Mech. Ageing Dev. (in Press). Sato, 2005, Effect of folate and mecobalamin on hip fractures in patients with stroke: a randomized controlled trial, JAMA, 293, 1082, 10.1001/jama.293.9.1082 Shelnutt, 2013, MyPyramid for Older Adults, J. Nutr. Educ. Behav., 41, 300, 10.1016/j.jneb.2008.07.007 Svetkey, 2005, Effect of lifestyle modifications on blood pressure by race, sex, hypertension status, and age, J. Hum. Hypertens., 19, 21, 10.1038/sj.jhh.1001770 Tokarz, 2008, Nutritional habits and supplementation of elderly people with cardiovascular diseases from Warsaw, Rocz. Panstw. Zakl. Hig., 59, 467 Trichopoulou, 1997, Healthy traditional Mediterranean diet: an expression of culture, history, and lifestyle, Nutr. Rev., 55, 383, 10.1111/j.1753-4887.1997.tb01578.x Trichopoulou, 2005, Modified Mediterranean diet and survival: EPIC-elderly prospective cohort study, BMJ, 330, 991, 10.1136/bmj.38415.644155.8F Troyer, 2010, The effect of home-delivered Dietary Approach to Stop Hypertension (DASH) meals on the diets of older adults with cardiovascular disease, Am. J. Clin. Nutr., 91, 1204, 10.3945/ajcn.2009.28780 van Dam, 2007, Potentially modifiable determinants of vitamin D status in an older population in the Netherlands: the Hoorn Study, Am. J. Clin. Nutr., 85, 755, 10.1093/ajcn/85.3.755 Vinas, 2011, Projected prevalence of inadequate nutrient intakes in Europe, Ann. Nutr. Metab., 59, 84, 10.1159/000332762 Vincent-Baudry, 2005, The Medi-RIVAGE study: reduction of cardiovascular disease risk factors after a 3-mo intervention with a Mediterranean-type diet or a low-fat diet, Am. J. Clin. Nutr., 82, 964, 10.1093/ajcn/82.5.964 Wannamethee, 2006, Associations of vitamin C status, fruit and vegetable intakes, and markers of inflammation and hemostasis, Am. J. Clin. Nutr., 83, 567, 10.1093/ajcn.83.3.567 Willett, 2013 Zazpe, 2008, A large randomized individual and group intervention conducted by registered dietitians increased adherence to Mediterranean-type diets: the PREDIMED study, J. Am. Diet. Assoc., 108, 1134, 10.1016/j.jada.2008.04.011