Repair of spinal cord injury in rats via exosomes from bone mesenchymal stem cells requires sonic hedgehog
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Zhang, 2021, Total flavonoids of hawthorn leaves promote motor function recovery via inhibition of apoptosis after spinal cord injury, Neural regeneration research, 16, 350, 10.4103/1673-5374.286975
Stephan, 2015, Spinal cord injury--incidence, prognosis, and outcome: an analysis of the TraumaRegister DGU, Spine J, 15, 1994, 10.1016/j.spinee.2015.04.041
Sun, 2020, Neurotrophin-3-Loaded multichannel nanofibrous scaffolds promoted anti-inflammation, neuronal differentiation, and functional recovery after spinal cord injury, ACS Biomater Sci Eng, 6, 1228, 10.1021/acsbiomaterials.0c00023
Yao, 2020, Mesenchymal stem cell-laden hydrogel microfibers for promoting nerve fiber regeneration in long-distance spinal cord transection injury, ACS Biomater Sci Eng, 6, 1165, 10.1021/acsbiomaterials.9b01557
Zou, 2020, Comparison of regenerative effects of transplanting three-dimensional longitudinal scaffold loaded-human mesenchymal stem cells and human neural stem cells on spinal cord completely transected rats, ACS Biomater Sci Eng, 6, 1671, 10.1021/acsbiomaterials.9b01790
Gong, 2020, Bioactive elastic scaffolds loaded with neural stem cells promote rapid spinal cord regeneration, ACS Biomater Sci Eng, 6, 6331, 10.1021/acsbiomaterials.0c01057
Ukeba, 2021, Bone marrow aspirate concentrate combined with in situ forming bioresorbable gel enhances intervertebral disc regeneration in rabbits, J bone and joint surgery American, 103, e31, 10.2106/JBJS.20.00606
Li, 2021, Combined transplantation of neural stem cells and bone marrow mesenchymal stem cells promotes neuronal cell survival to alleviate brain damage after cardiac arrest via microRNA-133b incorporated in extracellular vesicles, Aging, 13, 262, 10.18632/aging.103920
Li, 2020, hBMSC-derived extracellular vesicles attenuate IL-1β-induced catabolic effects on OA-chondrocytes by regulating pro-inflammatory signaling pathways, Frontiers in bioengineering and biotechnology, 8, 603598, 10.3389/fbioe.2020.603598
Wang, 2021, Obesity regulates miR-467/HoxA10 axis on osteogenic differentiation and fracture healing by BMSC-derived exosome LncRNA H19, J Cell Mol Med, 25, 1712, 10.1111/jcmm.16273
Lu, 2020, BMSC-derived exosomal miR-29a promotes angiogenesis and osteogenesis, Frontiers in cell and developmental biology, 8, 608521, 10.3389/fcell.2020.608521
Gu, 2020, Bone marrow mesenchymal stem cell-derived exosomes improves spinal cord function after injury in rats by activating autophagy, Drug Des Dev Ther, 14, 1621, 10.2147/DDDT.S237502
Moreau, 2020, Hedging against neuropathic pain: role of hedgehog signaling in pathological nerve healing, Int J Mol Sci, 21
Pan, 2020, Melatonin promotes Schwann cell proliferation and migration via the shh signalling pathway after peripheral nerve injury, Eur J Neurosci, 53, 720, 10.1111/ejn.14998
Yin, 2020, Neuroprotective effects of the sonic hedgehog signaling pathway in ischemic injury through promotion of synaptic and neuronal Health, Neural Plast, 2020, 8815195, 10.1155/2020/8815195
Angeloni, 2011, Regeneration of the cavernous nerve by Sonic hedgehog using aligned peptide amphiphile nanofibers, Biomaterials, 32, 1091, 10.1016/j.biomaterials.2010.10.003
Zhang, 2017, Lentivirus-mediated silencing of the PTC1 and PTC2 genes promotes recovery from spinal cord injury by activating the Hedgehog signaling pathway in a rat model, Exp Mol Med, 49, e412, 10.1038/emm.2017.220
Jia, 2021, Exosomes secreted from sonic hedgehog-modified bone mesenchymal stem cells facilitate the repair of rat spinal cord injuries, Acta Neurochir, 163, 2297, 10.1007/s00701-021-04829-9
Zhao, 2016, Adiponectin enhances bone marrow mesenchymal stem cell resistance to flow shear stress through AMP-activated protein kinase signaling, Sci Rep, 6, 28752, 10.1038/srep28752
Mohammadian, 2016, Effect of bone marrow derived mesenchymal stem cells on lung pathology and inflammation in ovalbumin-induced asthma in mouse, Iranian journal of basic medical sciences, 19, 55
Zeng, 2019, Lentivirus-mediated downregulation of α-synuclein reduces neuroinflammation and promotes functional recovery in rats with spinal cord injury, J Neuroinflammation, 16, 283, 10.1186/s12974-019-1658-2
Vafaei-Nezhad, 2020, A review of low-level laser therapy for spinal cord injury: challenges and safety, J Laser Med Sci, 11, 363
Li, 2016, Hedgehog signaling pathway as a therapeutic target for ovarian cancer, Cancer epidemiology, 40, 152, 10.1016/j.canep.2015.11.014
Jia, 2014, Bone marrow-derived mesenchymal stem cells expressing the Shh transgene promotes functional recovery after spinal cord injury in rats, Neurosci Lett, 573, 46, 10.1016/j.neulet.2014.05.010
Ren, 2020, Mesenchymal stem cell-derived exosomes: hope for spinal cord injury repair, Stem Cell Dev, 29, 1467, 10.1089/scd.2020.0133
Zhang, 2020, Exosomes derived from human placenta-derived mesenchymal stem cells improve neurologic function by promoting angiogenesis after spinal cord injury, Neurosci Lett, 739, 135399, 10.1016/j.neulet.2020.135399
Kong, 2019, Silencing of the MEKK2/MEKK3 pathway protects against spinal cord injury via the hedgehog pathway and the JNK pathway, Mol Ther Nucleic Acids, 17, 578, 10.1016/j.omtn.2019.05.014
Gao, 2021, Mild hypothermia protects rat cortical neurons against oxygen-glucose deprivation/reoxygenation injury via the PI3K/Akt pathway, Neuroreport, 32, 312, 10.1097/WNR.0000000000001593
Bhattacharyya, 2021, A combinatorial approach to modulate microenvironment toward regeneration and repair after spinal cord injury in rats, Neurosci Lett, 741, 135500, 10.1016/j.neulet.2020.135500
Liu, 2020, Effects of repetitive magnetic stimulation on motor function and GAP43 and 5-HT expression in rats with spinal cord injury, J Int Med Res, 48
Yao, 2021, Neurotropin exerts neuroprotective effects after spinal cord injury by inhibiting apoptosis and modulating cytokines, J orthopaedic translation, 26, 74, 10.1016/j.jot.2020.02.011
Ding, 2020, Acupuncture combined with moxibustion promote the recovery of spinal cord injury in correlation with Shh/Gli-1 signaling pathway, J spinal cord medicine, 1