Relevance of granulocyte apoptosis to resolution of inflammation at the respiratory mucosa

Mucosal Immunology - Tập 1 - Trang 350-363 - 2008
A E Leitch1, R Duffin1, C Haslett1, A G Rossi1
1MRC Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh Medical School, Edinburgh, Scotland, UK

Tài liệu tham khảo

Seaton, 2000 Rather, 1971, Disturbance of function (functio laesa): the legendary fifth cardinal sign of inflammation, added by Galen to the four cardinal signs of celsus, Bull NY Acad. Med, 47,, 303 Sabroe, 2007, Toll-like receptor (TLR)-based networks regulate neutrophilic inflammation in respiratory disease, Biochem. Soc. Trans, 35,, 1492, 10.1042/BST0351492 Rossi, 2007, Modulation of granulocyte apoptosis can influence the resolution of inflammation, Biochem. Soc. Trans, 35,, 288, 10.1042/BST0350288 Serhan, 2007, Resolution of inflammation: state of the art, definitions and terms, FASEB. J, 21,, 325, 10.1096/fj.06-7227rev von Kockritz-Blickwede, 2008, Phagocytosis-independent antimicrobial activity of mast cells by means of extracellular trap formation, Blood, 111,, 3070, 10.1182/blood-2007-07-104018 Brinkmann, 2004, Neutrophil extracellular traps kill bacteria, Science, 303,, 1532, 10.1126/science.1092385 Nathan, 2006, Neutrophils and immunity: challenges and opportunities, Nat. Rev. Immunol, 6,, 173, 10.1038/nri1785 Holgate, 2007, The future of lung research in the UK, Thorax, 62,, 1028, 10.1136/thx.2007.088971 British Thoracic Society. Health Select Committee inquiry into Health InequalitiesSubmission from the British Thoracic Society–08.01.08 (2008). Lachmann, 2002, Microbial subversion of the immune response, Proc. Natl. Acad. Sci. USA, 99,, 8461, 10.1073/pnas.132284499 Prince, 2008, Subversion of a lysosomal pathway regulating neutrophil apoptosis by a major bacterial toxin, pyocyanin, J. Immunol, 180,, 3502, 10.4049/jimmunol.180.5.3502 Haslett, 1999, Granulocyte apoptosis and its role in the resolution and control of lung inflammation, Am. J. Respir. Crit. Care. Med, 160,, S5, 10.1164/ajrccm.160.supplement_1.4 Sasmono, 2007, Mouse neutrophilic granulocytes express mRNA encoding the macrophage colony-stimulating factor receptor (CSF-1R) as well as many other macrophage-specific transcripts and can transdifferentiate into macrophages in vitro in response to CSF-1, J. Leukoc. Biol, 82,, 111, 10.1189/jlb.1206713 Araki, 2004, Reprogramming of human postmitotic neutrophils into macrophages by growth factors, Blood, 103,, 2973, 10.1182/blood-2003-08-2742 Opferman, 2007, Life and death during hematopoietic differentiation, Curr. Opin. Immunol, 19,, 497, 10.1016/j.coi.2007.06.002 Rossi, 2006, Cyclin-dependent kinase inhibitors enhance the resolution of inflammation by promoting inflammatory cell apoptosis, Nat. Med, 12,, 1056, 10.1038/nm1468 Sundaramurthy, 2007, Interactions of pathogenic mycobacteria with host macrophages, Microbes Infect, 9,, 1671, 10.1016/j.micinf.2007.09.007 Brinkmann, 2007, Beneficial suicide: why neutrophils die to make NETs, Nat. Rev. Microbiol, 5,, 577, 10.1038/nrmicro1710 Rothenberg, 2006, The eosinophil, Annu. Rev. Immunol, 24,, 147, 10.1146/annurev.immunol.24.021605.090720 Perretti, 2004, Annexin 1 and neutrophil apoptosis, Biochem. Soc. Trans, 32,, 507, 10.1042/bst0320507 Scannell, 2007, Annexin-1 and peptide derivatives are released by apoptotic cells and stimulate phagocytosis of apoptotic neutrophils by macrophages, J. Immunol, 178,, 4595, 10.4049/jimmunol.178.7.4595 Bianchi, 2006, Granulocyte apoptosis in the pathogenesis and resolution of lung disease, Clin. Sci, 110,, 293, 10.1042/CS20050178 Maianski, 2003, Tumor necrosis factor alpha induces a caspase-independent death pathway in human neutrophils, Blood, 101,, 1987, 10.1182/blood-2002-02-0522 Simon, 2003, Neutrophil apoptosis pathways and their modifications in inflammation, Immunol. Rev, 193,, 101, 10.1034/j.1600-065X.2003.00038.x Cowburn, 2005, z-VAD-fmk augmentation of TNF alpha-stimulated neutrophil apoptosis is compound specific and does not involve the generation of reactive oxygen species, Blood, 105,, 2970, 10.1182/blood-2004-07-2870 Simon, 2001, Regulation of eosinophil and neutrophil apoptosis–similarities and differences, Immunol. Rev, 179,, 156, 10.1034/j.1600-065X.2001.790115.x Simon, 2006, Molecules involved in the regulation of eosinophil apoptosis, Chem. Immunol. Allergy, 91,, 49, 10.1159/000090229 Simon, 1999, Regulation of eosinophil apoptosis: transduction of survival and death signals, Int. Arch. Allergy Immunol, 118,, 7, 10.1159/000024025 Daigle, 2001, Critical role for caspases 3 and 8 in neutrophil but not eosinophil apoptosis, Int. Arch. Allergy Immunol, 126,, 147, 10.1159/000049506 Ochiai, 1997, IL-5 but not interferon-gamma (IFN-gamma) inhibits eosinophil apoptosis by up-regulation of bcl-2 expression, Clin. Exp. Immunol, 107,, 198, 10.1046/j.1365-2249.1997.d01-884.x Weinmann, 1999, Bcl-Xl- and Bax-alpha-mediated regulation of apoptosis of human neutrophils via caspase-3, Blood, 93,, 3106, 10.1182/blood.V93.9.3106.409k36_3106_3115 Dzhagalov, 2007, The antiapoptotic protein Mcl-1 is essential for the survival of neutrophils but not macrophages, Blood, 109,, 1620, 10.1182/blood-2006-03-013771 Hamasaki, 1998, Accelerated neutrophil apoptosis in mice lacking A1-a, a subtype of the bcl-2-related A1 gene, J. Exp. Med, 188,, 1985, 10.1084/jem.188.11.1985 Sabroe, 2005, The role of Toll-like receptors in the regulation of neutrophil migration, activation, apoptosis, Clin. Infect. Dis, 41, S421, 10.1086/431992 Ward, 1999, NF-kappaB activation is a critical regulator of human granulocyte apoptosis in vitro, J. Biol. Chem, 274,, 4309, 10.1074/jbc.274.7.4309 Lawrence, 2001, Possible new role for NF-kappaB in the resolution of inflammation, Nat. Med, 7,, 1291, 10.1038/nm1201-1291 Pinho, 2005, Phosphoinositide-3 kinases critically regulate the recruitment and survival of eosinophils in vivo: importance for the resolution of allergic inflammation, J. Leukoc. Biol, 77,, 800, 10.1189/jlb.0704386 Pinho, 2007, Tissue- and stimulus-dependent role of phosphatidylinositol 3-kinase isoforms for neutrophil recruitment induced by chemoattractants in vivo, J. Immunol, 179,, 7891, 10.4049/jimmunol.179.11.7891 Savill, 1995, Granulocyte clearance by apoptosis in the resolution of inflammation, Semin. Cell. Biol, 6,, 385, 10.1016/S1043-4682(05)80009-1 Sivertson, 2007, The differential effect of dexamethasone on granulocyte apoptosis involves stabilization of Mcl-1L in neutrophils but not in eosinophils, Cell. Immunol, 246,, 34, 10.1016/j.cellimm.2007.05.003 Heasman, 2003, Glucocorticoid-mediated regulation of granulocyte apoptosis and macrophage phagocytosis of apoptotic cells: implications for the resolution of inflammation, J. Endocrinol, 178,, 29, 10.1677/joe.0.1780029 Serhan, 2007, Resolution phase of inflammation: novel endogenous anti-inflammatory and proresolving lipid mediators and pathways, Annu. Rev. Immunol, 25,, 101, 10.1146/annurev.immunol.25.022106.141647 Hallett, 2008, Novel pharmacological strategies for driving inflammatory cell apoptosis and enhancing the resolution of inflammation, Trends Pharmacol. Sci, 29,, 250, 10.1016/j.tips.2008.03.002 Kobayashi, 2007, TIM-1 and TIM-4 glycoproteins bind phosphatidylserine and mediate uptake of apoptotic cells, Immunity, 27,, 927, 10.1016/j.immuni.2007.11.011 Park, 2008, Rapid cell corpse clearance by stabilin-2, a membrane phosphatidylserine receptor, Cell Death Differ, 15,, 192, 10.1038/sj.cdd.4402242 Park, 2007, BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module, Nature, 450,, 430, 10.1038/nature06329 Fadok, 1998, Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, PAF, J. Clin. Invest, 101,, 890, 10.1172/JCI1112 Barnes, P.J. Alveolar macrophages in chronic obstructive pulmonary disease (COPD). Cell. Mol. Biol. 50, Online Pub:OL627-OL637 (2004). Barnes, 2007, New molecular targets for the treatment of neutrophilic diseases, J. Allergy Clin. Immunol, 119,, 1055, 10.1016/j.jaci.2007.01.015 MacNee, 2007, Pathogenesis of chronic obstructive pulmonary disease, Clin. Chest Med, 28,, 479, 10.1016/j.ccm.2007.06.008 Kirkham, 2004, Macrophage phagocytosis of apoptotic neutrophils is compromised by matrix proteins modified by cigarette smoke and lipid peroxidation products, Biochem. Biophys. Res. Commun, 318,, 32, 10.1016/j.bbrc.2004.04.003 Barnes, 2004, Corticosteroid resistance in chronic obstructive pulmonary disease: inactivation of histone deacetylase, Lancet, 363,, 731, 10.1016/S0140-6736(04)15650-X Quint, 2007, The neutrophil in chronic obstructive pulmonary disease, J. Allergy Clin. Immunol, 119,, 1065, 10.1016/j.jaci.2006.12.640 Barnes, 1996, Pathophysiology of asthma, Br. J. Clin. Pharmacol, 42,, 3, 10.1046/j.1365-2125.1996.03721.x Busse, 2000, Pathophysiology of severe asthma, J. Allergy Clini. Immunol, 106,, 1033, 10.1067/mai.2000.111307 Hanania, 2008, Targeting airway inflammation in asthma: current and future therapies, Chest, 133,, 989, 10.1378/chest.07-0829 Holgate, 2006, Understanding the pathophysiology of severe asthma to generate new therapeutic opportunities, J. Allergy Clin. Immunol, 117,, 496, 10.1016/j.jaci.2006.01.039 Maddox, 2002, The pathophysiology of asthma, Annu. Rev. Med, 53,, 477, 10.1146/annurev.med.53.082901.103921 Walsh, 2003, Corticosteroids, eosinophils and bronchial epithelial cells: new insights into the resolution of inflammation in asthma, J. Endocrinol, 178,, 37, 10.1677/joe.0.1780037 Contoli, 2006, Role of deficient type III interferon-[lambda] production in asthma exacerbations, Nat. Med, 12,, 1023, 10.1038/nm1462 Uddin, 2008, Enhancement of neutrophil function by the bronchial epithelium stimulated by epidermal growth factor, Eur. Respir. J, 31,, 714, 10.1183/09031936.00144307 Flood-Page, 2003, Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics, J. Clin. Invest, 112,, 1029, 10.1172/JCI17974 Flood-Page, 2003, Eosinophil's role remains uncertain as anti-interleukin-5 only partially depletes numbers in asthmatic airway, Am. J. Respir. Crit. Care. Med, 167,, 199, 10.1164/rccm.200208-789OC Wenzel, 2007, Effect of an interleukin-4 variant on late phase asthmatic response to allergen challenge in asthmatic patients: results of two phase 2a studies, Lancet, 370,, 1422, 10.1016/S0140-6736(07)61600-6 Bullens, 2006, IL-17 mRNA in sputum of asthmatic patients: linking T cell driven inflammation and granulocytic influx?, Respir. Res, 7,, 113, 10.1186/1465-9921-7-135 Meagher, 1996, Opposing effects of glucocorticoids on the rate of apoptosis in neutrophilic and eosinophilic granulocytes, J. Immunol, 156,, 4422, 10.4049/jimmunol.156.11.4422 Wenzel, 2003, A different disease, many diseases or mild asthma gone bad? Challenges of severe asthma, Eur. Respir. J, 22,, 397, 10.1183/09031936.03.00027403 Collard, 2007, Acute exacerbations of idiopathic pulmonary fibrosis, Am. J. Respir. Crit. Care. Med, 176,, 636, 10.1164/rccm.200703-463PP Du Bois, 2007, Challenges in pulmonary fibrosis x 5: the NSIP/UIP debate, Thorax, 62,, 1008, 10.1136/thx.2004.031039 Hunninghake, 2007, State of the Art. Does current knowledge explain the pathogenesis of idiopathic pulmonary fibrosis?: a perspective, Proc. Am. Thorac. Soc, 4,, 449, 10.1513/pats.200702-036MS Wallace, 2007, Inflammation-associated remodelling and fibrosis in the lung - a process and an end point, Int. J. Exp. Pathol, 88,, 103, 10.1111/j.1365-2613.2006.00515.x Strieter, 2008, What differentiates normal lung repair and fibrosis? Inflammation, resolution of repair, fibrosis, Proc. Am. Thorac. Soc, 5,, 305, 10.1513/pats.200710-160DR Chua, 2007, Mice lacking neutrophil elastase are resistant to bleomycin-induced pulmonary fibrosis, Am. J. Pathol, 170,, 65, 10.2353/ajpath.2007.060352 Kinder, 2008, Baseline BAL neutrophilia predicts early mortality in idiopathic pulmonary fibrosis, Chest, 133,, 226, 10.1378/chest.07-1948 Abraham, 2003, Neutrophils and acute lung injury, Crit. Care. Med, 31,, S195, 10.1097/01.CCM.0000057843.47705.E8 Bellingan, 2002, The pulmonary physician in critical care * 6: The pathogenesis of ALI/ARDS, Thorax, 57,, 540, 10.1136/thorax.57.6.540 Leaver, 2007, Acute respiratory distress syndrome, BMJ, 335,, 389, 10.1136/bmj.39293.624699.AD Martin, 2008, Interactions between mechanical and biological processes in acute lung injury, Proc. Am. Thorac. Soc, 5,, 291, 10.1513/pats.200801-005DR Matthay, 2005, Acute lung injury and the acute respiratory distress syndrome: four decades of inquiry into pathogenesis and rational management, Am. J. Respir. Cell. Mol. Biol, 33,, 319, 10.1165/rcmb.F305 Donnelly, 1993, Interleukin-8 and development of adult respiratory distress syndrome in at-risk patient groups, Lancet, 341,, 643, 10.1016/0140-6736(93)90416-E Oeckler, 2007, Ventilator-associated lung injury: a search for better therapeutic targets, Eur. Respir. J, 30,, 1216, 10.1183/09031936.00104907 British Thoracic Society, 2001, BTS Guidelines for the Management of Community Acquired Pneumonia in Adults, Thorax, 56, IV1 Droemann, 2000, Decreased apoptosis and increased activation of alveolar neutrophils in bacterial pneumonia, Chest, 117,, 1679, 10.1378/chest.117.6.1679 Watson, 1996, Neutrophils undergo apoptosis following ingestion of Escherichia coli, J. Immunol, 156,, 3986, 10.4049/jimmunol.156.10.3986 Cazzola, 2005, Inflammation–a new therapeutic target in pneumonia, Respiration, 72,, 117, 10.1159/000084039 Confalonieri, 2005, Hydrocortisone infusion for severe community-acquired pneumonia: a preliminary randomized study, Am. J. Respir. Crit. Care. Med, 171,, 242, 10.1164/rccm.200406-808OC Elizur, 2008, Airway inflammation in cystic fibrosis, Chest, 133,, 489, 10.1378/chest.07-1631 Sabroe, 2007, Incapacitating the immune system in cystic fibrosis, Nat. Med, 13,, 1417, 10.1038/nm1207-1417 Brodmerkel, 2003, Transgenic animals in inflammatory disease models, Curr. Opin. Biotechnol, 14,, 652, 10.1016/j.copbio.2003.10.001 Guilbault, 2007, Cystic fibrosis mouse models, Am. J. Respir. Cell. Mol. Biol, 36,, 1, 10.1165/rcmb.2006-0184TR Kips, 2003, Murine models of asthma, Eur. Respir. J, 22,, 374, 10.1183/09031936.03.00026403 Moeller, 2006, Models of pulmonary fibrosis, Drug Discov. Today Dis. Models, 3,, 243, 10.1016/j.ddmod.2006.09.006 Moore, 2008, Murine models of pulmonary fibrosis, Am. J. Physiol. Lung Cell. Mol. Physiol, 294,, L152, 10.1152/ajplung.00313.2007 Renshaw, 2007, Modeling inflammation in the zebrafish: how a fish can help us understand lung disease, Exp. Lung Res, 33,, 549, 10.1080/01902140701756778 Harrison, 1987, High dose continuous infusion of bleomycin in mice: a new model for drug-induced pulmonary fibrosis, J. Pharmacol. Exp. Ther, 243,, 1185 Moeller, 2008, The bleomycin animal model: a useful tool to investigate treatment options for idiopathic pulmonary fibrosis?, Int. J. Biochem. Cell. Biol, 40,, 362, 10.1016/j.biocel.2007.08.011 Hardie, 2004, Conditional expression of transforming growth factor-alpha in adult mouse lung causes pulmonary fibrosis, Am. J. Physiol. Lung. Cell. Mol. Physiol, 286,, L741, 10.1152/ajplung.00208.2003 Sime, 1997, Adenovector-mediated gene transfer of active transforming growth factor-beta 1 induces prolonged severe fibrosis in rat lung, J. Clin. Investig, 100,, 768, 10.1172/JCI119590 Xing, 1996, Gene transfer for cytokine functional studies in the lung: the multifunctional role of GM-CSF in pulmonary inflammation, J. Leukoc. Biol, 59,, 481, 10.1002/jlb.59.4.481 Kolb, 2001, Transient expression of IL-1 beta induces acute lung injury and chronic repair leading to pulmonary fibrosis, J. Clin. Investig, 107,, 1529, 10.1172/JCI12568 Miyazaki, 1995, Expression of a tumor-necrosis-factor-alpha transgene in murine lung causes lymphocytic and fibrosing alveolitis - a mouse model of progressive pulmonary fibrosis, J. Clin. Investig, 96,, 250, 10.1172/JCI118029 Elias, 2003, Transgenic modeling of interleukin-13 in the lung, Chest, 123,, 339S, 10.1378/chest.123.3_suppl.339S Zosky, 2007, Animal models of asthma, Clin. Exp. Allergy, 37,, 973, 10.1111/j.1365-2222.2007.02740.x Churg, 2008, Mechanisms of cigarette smoke-induced COPD: insights from animal models, Am. J. Physiol. Lung. Cell. Mol. Physiol, 294,, L612, 10.1152/ajplung.00390.2007 Fujita, 2007, The pathogenesis of COPD: lessons learned from in vivo animal models, Med. Sci. Monit, 13,, RA19 Shapiro, 2007, Transgenic and gene-targeted mice as models for chronic obstructive pulmonary disease, Eur. Respir. J, 29,, 375, 10.1183/09031936.00087606 Dos Santos, 2007, Hyperoxic acute lung injury and ventilator-induced/associated lung injury: new insights into intracellular signaling pathways, Crit. Care, 11,, 112, 10.1186/cc5733 Kabir, 2002, Characterization of a murine model of endotoxin-induced acute lung injury, Shock, 17,, 300, 10.1097/00024382-200204000-00010 Moine, 1997, Systemic blood loss affects NF-kappa B regulatory mechanisms in the lungs, Am. J. Physiol. Lung. Cell. Mol. Physiol, 273,, L185, 10.1152/ajplung.1997.273.1.L185 Bahrami, 2006, Small-volume fluid resuscitation with hypertonic saline prevents inflammation but not mortality in a rat model of hemorrhagic shock, Shock, 25,, 283, 10.1097/01.shk.0000208808.03148.ea London, 2002, Respiratory reovirus 1/L induction of diffuse alveolar damage: a model of acute respiratory distress syndrome, Exp. Mol. Pathol, 72,, 24, 10.1006/exmp.2001.2414