Relative potencies of 5-lipoxygenase inhibitors on antigeninduced contractions of guinea pig tracheal strips

Adams, 1979, In vitro studies of antigen-induced bronchospasm: Effect of antihistamine and SRS-A antagonist on response of sensitized guinea pig and human airways to antigen, J Immunol, 122, 555, 10.4049/jimmunol.122.2.555 Ashida, 1983, Pharmacological profile of AA-861, a 5-lipoxygenase inhibitor, Prostaglandins, 26, 955, 10.1016/0090-6980(83)90157-0 Burka, 1981, The effects of SRS-A and histamine antagonists on antigen-induced contractions of guinea pig trachea, Eur J Pharmacol, 70, 489, 10.1016/0014-2999(81)90360-5 Burka, 1980, Evidence for lipoxygenase pathway involvement in allergic tracheal contractions, Prostaglandins, 19, 499, 10.1016/S0090-6980(80)80001-3 Dale, 1913, The anaphylactic reaction of plain muscle in the guinea pig, J Pharmacol Exp Ther, 4, 167 Fleisch, 1985, LY171883, 1- < 2-Hydroxy-3-propyl-4- < 4-(1H-te-trazol-5-yl) butoxy>phenyl>ethanone, an orally active leukotriene D4 antagonist, J Pharmacol Exp Ther, 233, 148 Hand, 1979, Effects of selected antagonists on ovalbumin-induced contraction of tracheal strip isolated from the actively sensitized guinea pig, Int J Immunopharmacol, 1, 189, 10.1016/0192-0561(79)90041-9 Hand, 1989, WY-48,252 (1,1,1-trifluoro-N-[3-(2-quinolinylmethoxy) phenyl] methane sulfonamide) an orally active leukotriene D4 antagonist: Pharmacological characterization in vitro and in vivo in the guinea pig, Prostaglandins Leukotrienes Essential Fatty Acids, 37, 97, 10.1016/0952-3278(89)90105-1 Hand, 1986, Antagonism of antigen-induced contraction of isolated guinea-pig trachea by 5-lipoxygenase inhibitors, Int Archs Allergy Appl Immunol, 79, 8, 10.1159/000233934 Hay, 1987, Pharmacologic profile of SK&F 104353: A novel, potent and selective peptidoleukotriene receptor antagonist in guinea pig and human airways, J Pharmacol Exp Ther, 243, 474 Huang, 1989, Differential effects of a series of hydroxamic acid derivatives on 5-lipoxygenase and cyclooxygenase from neutrophils and 12-lipoxygenase from platelets and their in vivo effects on inflammation and anaphylaxis, J Med Chem, 32, 1836, 10.1021/jm00128a027 Jones, 1986, L-649, 923,Sodium (βS∗,γR∗)-4-(3-(4-acetyl-3-hydroxy-2-propylphenoxy)-propylthio)-γ-hydroxy-β-methyl-benzene-butanoate, a selective, orally active leukotriene receptor antagonist, Can J Physiol Pharmacol, 64, 1068, 10.1139/y86-183 Jones, 1988, Antigen-induced contraction of guinea-pig isolated trachea: Studies with novel inhibitors and antagonists of arachidonic acid metabolites, Br J Pharmacol, 95, 309, 10.1111/j.1476-5381.1988.tb16578.x Jones, 1989, Pharmacology of L-660,711 (MK-571): A novel potent and selective leukotriene D4 receptor antagonist, Can J Physiol Pharmacol, 67, 17, 10.1139/y89-004 Krell, 1981, Contraction of isolated airway smooth muscle by synthetic leukotrienes C4 and D4, Prostaglandins, 22, 387, 10.1016/0090-6980(81)90101-5 Redkar-Brown, 1989, Inhibition of antigen-induced contraction of guinea pig trachea by ICI 198615, Eur J Pharmacol, 165, 113, 10.1016/0014-2999(89)90776-0 Rouzer, 1990, MK886, a potent and specific leukotriene biosynthesis inhibitor blocks and reverses the membrane association of 5-lipoxygenase in ionophore-challenged leukocytes, J Biol Chem, 265, 1436, 10.1016/S0021-9258(19)40034-3 Schultz, 1910, Physiological studies in anaphylaxis. I. The reaction of smooth muscle of the guinea pig sensitized with horse serum, J Pharmacol Exp Ther, 1, 549 Snyder, 1991, Endognously formed leukotriene C4 activates LTC4 receptors in guinea pig tracheal strips, Eur J Pharmacol, 195, 209, 10.1016/0014-2999(91)90537-Z Snyder, 1987, In vitro pharmacology of ICI 198,615: A novel, potent and selective peptide leukotriene antagonist, J Pharmacol Exp Ther, 243, 548 Summers, 1987, Hydroxamic acid inhibitors of 5-lipoxygenase, J Med Chem, 30, 574, 10.1021/jm00386a022 Sweeney, 1987, The effect of a novel inhibitor of 5-lipoxygenase on pulmonary anaphylaxis in sensitized guinea pigs, 46, 540 Van Rossum, 1963, Cumulative dose-response curves. II. Technique for the making of doseresponse curves in isolated organs and the evaluation of drug parameters, Arch Int Pharmacodyn Ther, 143, 299 Yoshimoto, 1982, 2,3,5-Trimethyl-6-(12-hydroxy-5,10-dodecadinyl)-1,4-benzoquinone (AA861), a selective inhibitor of the 5-lipoxygenase reaction and biosynthesis of slow-reacting substance of anaphylaxis, Biochim Biophys Acta, 713, 470, 10.1016/0005-2760(82)90267-3