Relationship between changes in hemoglobin glycosilated and improvement of body composition in patients with morbid obesity after tubular laparoscopic gastrectomy

Medicina Clínica (English Edition) - Tập 151 - Trang 131 - 2018
Cambil-Martín Jacobo, Fernández-Lao Carolina, Cantarero-Villanueva Irene, Arroyo-Morales Manuel, Jiménez Ríos José Antonio, Gallart-Aragón Tania, Cózar-Ibañez Antonio

Tóm tắt

Background and objective The objective of our study is to analyze the possible relationship between changes in glycemic profile and body composition parameters in morbid obesity patients after tubular laparoscopic gastrectomy. Material and methods A prospective observational cohort study with 69 patients was performed. The variables analyzed were body weight, blood glucose, haemoglobin, glycosylated, high density lipoprotein, low density lipoprotein, triglycerides, and waist and hip circumference. An analysis of variance of repeated measurements (ANOVA) and a correlation analysis through the Pearson test were carried out. Results A significant reduction in weight (p <0.001 after surgery) and in glycosylated haemoglobin (p <0.036) and waist hip (p <0.001) were found at 6 months after surgery. There was no significant difference in the rest of the variables studied. In correlation analysis, a significant positive correlation was found between the change in concentration of haemoglobin glycosylated and hip circumference (p =0.047; r =0.237), the smaller the hip circumference, the lower the concentration of glycosylated haemoglobin. Conclusions Tubular laparoscopic gastrectomy is an effective technique for the treatment of morbidly obese patients with type 2 diabetes mellitus. The reduction in the perimeter of hip is related to glycosylated haemoglobin reduction 6 months after intervention.

Từ khóa

#Diabetes mellitus #Morbid obesity #Tubular laparoscopic gastrectomy #Diabetes mellitus #Gastrectomía tubular laparoscópica #Obesidad mórbida