Regulation of testicular descent

Pediatric Surgery International - Tập 31 Số 4 - Trang 317-325 - 2015
John M. Hutson1, Ruili Li1, Bridget R. Southwell1, Don Newgreen1, Mary Cousinery1
1F Douglas Stephens Surgical Research Group and Embryology Laboratory, Murdoch Childrens Research Laboratory, Melbourne, Australia

Tóm tắt

Từ khóa


Tài liệu tham khảo

Hutson J (1985) A biphasic model for the hormonal control of testicular descent. Lancet 2(8452):419–420

Hutson JM et al (2014) The power and perils of animal models with urogenital anomalies: handle with care. J Pediatr Urol 10(4):699–705

Lee MM, Donahoe PK (1993) Mullerian inhibiting substance: a gonadal hormone with multiple functions. Endocr Rev 14(2):152–164

Lane AH, Donahoe PK (1998) New insights into mullerian inhibiting substance and its mechanism of action. J Endocrinol 158(1):1–6

Heyns CF (1990) Exstrophy of the testis. J Urol 144:724–725

Backhouse KM (1964) The gubernaculum testis hunteri: testicular descent and maldescent. Ann Royal Colleg Surg Engl 35:15–33

Nef S, Parada LF (1999) Cryptorchidism in mice mutant for Insl3. Nat Genet 22(3):295–299

Zimmermann S et al (1999) Targeted disruption of the Insl3 gene causes bilateral cryptorchidism. Mol Endocrinol 13(5):681–691

Ivell R, Hartung S, Anand-Ivell R (2005) Insulin-like factor 3: where are we now? Ann N Y Acad Sci 1041(1):486–496

Kubota Y et al (2001) Leydig insulin-like hormone, gubernacular development and testicular descent. J Urol 165(5):1673–1675

Adham IM et al (2002) The overexpression of the insl3 in female mice causes descent of the ovaries. Mol Endocrinol 16(2):244–252

Chen N et al (2011) Gone with the Wnt: the canonical Wnt signaling axis is present and androgen dependent in the rodent gubernaculum. J Pediatr Surg 46(12):2363–2369

Kaftanovskaya EM et al (2011) Suppression of insulin-like3 receptor reveals the role of beta-catenin and Notch signaling in gubernaculum development. Mol Endocrinol 25(1):170–183

Bay K et al (2011) Testicular descent: INSL3, testosterone, genes and the intrauterine milieu. Nat Rev Urol 8(4):187–196

Virtanen HE, Toppari J (2008) Epidemiology and pathogenesis of cryptorchidism. Hum Reprod Update 14(1):49–58

Ferlin A et al (2007) Hormonal and genetic control of testicular descent. Reprod Biomed Online 15(6):659–665

Virtanen HE, Toppari J (2014) Embryology and physiology of testicular development and descent. Pediatric Endocrinol Rev PER 11(Suppl 2):206–213

Hutson JM, Baker ML (1994) A hypothesis to explain abnormal gonadal descent in persistent mullerian duct syndrome. Pediatr Surg Int 9:542–543

Hutson JM, Chow CW, Ng W-D (1987) Persistent mullerian duct syndrome with transverse testicular ectopia. Pediatr Surg Int 2:191–194

Imbeaud S et al (1995) Testicular degeneration in three patients with the persistent mullerian duct syndrome. Eur J Pediatr 154(3):187–190

Huynh J et al (2007) Signalling molecules: clues from development of the limb bud for cryptorchidism? Pediatr Surg Int 23(7):617–624

Wolpert L (1999) Vertebrate limb development and malformations. Pediatr Res 46(3):247–254

Dudley AT, Ros MA, Tabin CJ (2002) A re-examination of proximodistal patterning during vertebrate limb development. Nature 418(6897):539–544

Nation T et al (2009) The antiandrogen flutamide perturbs inguinoscrotal testicular descent in the rat and suggests a link with mammary development. J Pediatr Surg 44(12):2330–2334

Su S et al (2012) Regression of the mammary branch of the genitofemoral nerve may be necessary for testicular descent in rats. J Urol 188(4 Suppl):1443–1448

Coveney D et al (2002) The development of the gubernaculum and inguinal closure in the marsupial Macropus eugenii. J Anat 201:239–256

Nightingale SS, Western P, Hutson JM (2008) The migrating gubernaculum grows like a “limb bud”. J Pediatr Surg 43(2):387–390

Krajnc-Franken MA et al (2004) Impaired nipple development and parturition in LGR7 knockout mice. Mol Cell Biol 24(2):687–696

Na AF et al (2007) Cell membrane and mitotic markers show that the neonatal rat gubernaculum grows in a similar way to an embryonic limb bud. J Pediatr Surg 42(9):1566–1573

Churchill JA et al (2011) Gubernaculum as icebreaker: do matrix metalloproteinases in rodent gubernaculum and inguinal fat pad permit testicular descent? J Pediatr Surg 46(12):2353–2357

Das S, Singer A (1990) Controversies of perinatal torsion of the spermatic cord: a review, survery and recommendations. J Urol 143:231–233

Welsh M et al (2008) Identification in rats of a programming window for reproductive tract masculinization, disruption of which leads to hypospadias and cryptorchidism. J Clin Invest 118(4):1479–1490

Nation TR et al (2011) The effect of flutamide on expression of androgen and estrogen receptors in the gubernaculum and surrounding structures during testicular descent. J Pediatr Surg 46(12):2358–2362

Lewis LG (1948) Cryptorchism. J Urol 60:345–356

Beasley SW, Hutson JM (1987) Effect of division of genitofemoral nerve on testicular descent in the rat. ANZ J Surg 57:49–51

Schwindt B et al (1999) Localization of calcitonin gene-related peptide within the genitofemoral nerve in immature rats. J Pediatr Surg 34(6):986–991

Yamanaka J, Metcalfe SA, Hutson JM (1992) Demonstration of calcitonin gene-related peptide receptors in the gubernaculum by computerized densitometry. J Pediatr Surg 27:876–878

Yamanaka J et al (1993) Testicular descent. II. Ontogeny and response to denervation of calcitonin gene-related peptide receptors in neonatal rat gubernaculum. Endocrinology 132(1):280–284

Hrabovszky Z, Hutson JM (1999) Capsaicin restores gubernacular contractility in TS rats. J Pediatr Surg 34(12):1769–1772

Park W-H, Hutson JM (1991) The gubernaculum shows rhythmic contractility and active movement during testicular descent. J Pediatr Surg 26(5):615–617

Momose Y, Griffiths AL, Hutson JM (1992) Testicular descent III. The neonatal gubernaculum shows rhythmic contraction in organ culture in response to calcitonin gene-related peptide. Endocrinology 131:2881–2884

Terada M et al (1994) Ontogeny of Gubernacular Contraction and Effect of Calcitonin Gene-Related Peptide in the Mouse. J Pediatr Surg 29(5):609–611

Yong EXZ et al (2008) Calcitonin gene-related peptide stimulates mitosis in the tip of the rat gubernaculum in vitro and provides the chemotactic signals to control gubernacular migration during testicular descent. J Pediatr Surg 43(8):1533–1539

Shenker NS et al (2006) A new role for androgen in testicular descent: permitting gubernacular cell proliferation in response to the neuropeptide, calcitonin gene-related peptide. J Pediatr Surg 41(2):407–412

Ng YH et al (2009) Growth of the rat gubernaculum in vitro and localisation of its growth centre. J Pediatr Surg 44(2):422–426

Terada M et al (1994) Calcitonin gene-related peptide receptors in the gubernaculum of normal rat and 2 models of cryptorchidism. J Urol 152(2 Pt 2):759–762

Terada M et al (1995) The role of the genitofemoral nerve and CGRP in congenitally cryptorchid mutant TS rats. J Urol 154:734–737

Nation T et al (2011) Androgen and estrogen receptor expression in the spinal segments of the genitofemoral nerve during testicular descent. J Pediatr Surg 46(8):1539–1543

Sengelaub DR et al (1989) Hormonal control of neuron number in sexually dimorphic spinal nuclei of the rat: III. differential effects of the androgen dihydrotestosterone. J Comp Neurol 280(4):637–644

Popper P, Micevych PE (1990) Steroid regulation of calcitonin gene-related peptide mRNA expression in motoneurons of the spinal nucleus of the bulbocavernosus. Brain Res Mol Brain Res 8(2):159–166

Yang LY, Verhovshek T, Sengelaub DR (2004) Brain-derived neurotrophic factor and androgen interact in the maintenance of dendritic morphology in a sexually dimorphic rat spinal nucleus. Endocrinology 145(1):161–168

Forger NG et al (1998) Ciliary neurotrophic factor receptor alpha in spinal motoneurons is regulated by gonadal hormones. J Neurosci 18(21):8720–8729

Bartoletti A et al (2002) Heterozygous knock-out mice for brain-derived neurotrophic factor show a pathway-specific impairment of long-term potentiation but normal critical period for monocular deprivation. J Neurosci 22(23):10072–10077

DeChiara TM et al (1995) Mice lacking the CNTF receptor, unlike mice lacking CNTF, exhibit profound motor neuron deficits at birth. Cell 83(2):313–322

Liu Y et al (2012) Sexually dimorphic BDNF signaling directs sensory innervation of the mammary gland. Science 338(6112):1357–1360

Husmann DA (2009) Testicular descent: a hypothesis and review of current controversies. Pediatr Endocrinol Rev 6(4):491–495

Clarnette TD, Hutson JM (1996) The genitofemoral nerve may link testicular inguinoscrotal descent with congenital inguinal hernia. Aust NZ J Surg 66(9):612–617

Buraundi S et al (2011) Gubernacular development in the mouse is similar to the rat and suggests that the processus vaginalis is derived from the urogenital ridge and is different from the parietal peritoneum. J Pediatr Surg 46(9):1804–1812

Clarnette TD, Hutson JM, Beasley SW (1996) Factors affecting the development of the processus vaginalis in the rat. J Urol 156(4):1463–1466

Clarnette TD, Lam SKL, Hutson JM (1998) Ventriculo-Peritoneal shunts in children reveal the natural history of closure of the processus vaginalis. J Pediatr Surg 33:413–416

Hadziselimovic F et al (2007) Infertility in cryptorchidism is linked to the stage of germ cell development at orchidopexy. Horm Res 68(1):46–52

Sugita Y et al (1999) Calcitonin gene-related peptide (CGRP)-immunoreactive nerve fibres and receptors in the human processus vaginalis. Hernia 3:113–116

Hutson JM et al (2000) In vitro fusion of human inguinal hernia with associated epithelial transformation. Cells Tissues Organs 166(3):249–258

Cook BJ, Hasthorpe S, Hutson JM (2000) Fusion of childhood inguinal hernia induced by HGF and CGRP via an epithelial transition. J Pediatr Surg 35(1):77–81

Hutson JM, Temelcos C (2005) Could inguinal hernia be treated medically? Med Hypotheses 64(1):37–40

Hrabovszky Z, Hutson JM (2002) Androgen imprinting of the brain in animal models and humans with intersex disorders: review and recommendations. J Urol 168:2142–2148

Clarnette TD et al (1997) Incomplete disappearance of the processus vaginalis as a cause of ascending testis. J Urol 157:1889–1891

Kollin C, Ritzen EM (2014) Cryptorchidism: a clinical perspective. Pediatric Endocrinol Rev PER 11(Suppl 2):240–250