Regulation of mitochondrial dehydrogenases by calcium ions

Biochimica et Biophysica Acta (BBA) - Bioenergetics - Tập 1787 Số 11 - Trang 1309-1316 - 2009
Richard M. Denton1
1Department of Biochemistry, School of Medical Sciences, University of Bristol, University Walk, Bristol, BS8 ITD, UK. [email protected]

Tóm tắt

Từ khóa


Tài liệu tham khảo

Hansford, 1967, Effect of Ca2+ on oxidation of glycerol phosphosphate by blowfly flight-muscle mitochondria, Biochem. Biophys. Res. Commun., 27, 686, 10.1016/S0006-291X(67)80090-1

Denton, 1972, Stimulation by calcium-ions of pyruvate dehydrogenase phosphate phosphatase, Biochem. J., 128, 161, 10.1042/bj1280161

Denton, 1978, Calcium-ions and the regulation of NAD+-linked isocitrate dehydrogenase from the mitochondria of rat-heart and other tissues, Biochem. J., 176, 899, 10.1042/bj1760899

McCormack, 1979, Effects of calcium-ions and adenine-nucleotides on the activity of pig-heart 2-oxoglutarate dehydrogenase complex, Biochem. J., 180, 533, 10.1042/bj1800533

Denton, 1980, On the role of the calcium-transport cycle in heart and other mammalian mitochondria, FEBS Lett., 119, 1, 10.1016/0014-5793(80)80986-0

McCormack, 1990, Role of calcium-ions in regulation of mammalian intramitochondrial metabolism, Physiol. Rev., 70, 391, 10.1152/physrev.1990.70.2.391

Hansford, 1985, Relation between mitochondrial calcium-transport and control of energy-metabolism, Rev. Physiol., Biochem. Pharmacol., 102, 1, 10.1007/BFb0034084

Hansford, 1991, Dehydrogenase activation by Ca2+ in cells and tissues, J. Bioenerg. Biomembranes, 23, 823, 10.1007/BF00786004

Nichols, 1995, Towards the molecular-basis for the regulation of mitochondrial dehydrogenases by calcium-ions, Mol. Cell. Biochem., 149, 203, 10.1007/BF01076578

McCormack, 1999, Calcium in the regulation of intramitochondrial enzymes, 529

E.J. Griffiths, G.A. Rutter, Mitochondrial calcium as a key regulator of mitochondrial ATP production, Biochim. Biophys. (2009-this issue).

Estabrook, 1958, Alpha-glycerophosphate oxidase of flight muscle mitochondria, J. Biol. Chem., 233, 1014, 10.1016/S0021-9258(18)64696-4

Portzehl, 1964, Dependence of contraction and relaxation of muscle fibres from crab Maia squinado on internal concentration of free calcium ions, Biochim. Biophys. Acta, 79, 581

Linn, 1969, Alpha-keto acid dehydrogenase complexes. x. Regulation of activity of pyruvate dehydrogenase complex from beef kidney mitochondria by phosphorylation and dephosphorylation, Proc. Natl. Acad. Sci. U. S. A., 62, 234, 10.1073/pnas.62.1.234

Denton, 1971, Insulin activates pyruvate dehydrogenase in rat epididymal adipose tissue, Nature New Biol., 231, 115, 10.1038/newbio231115a0

Denton, 1989, Studies into the mechanism whereby insulin activates pyruvate-dehydrogenase complex in adipose-tissue, Ann. N.Y. Acad. Sci., 573, 285, 10.1111/j.1749-6632.1989.tb15005.x

Vaughan, 1970, Effects of calcium ions and adenosine diphosphate on activity of nicotinamide-adenine dinucleotide-linked isocitrate dehydrogenase muscle, Biochem. J., 116, P23, 10.1042/bj1160023Pa

Zammit, 1976, Effects of calcium-ions and adenosine-diphosphate on activities of NAD+-linked isocitrate dehydrogenase from radular muscles of whelk and flight muscles of insects, Biochem. J., 154, 677, 10.1042/bj1540677

Williamson, 1980, Regulation of the citric-acid cycle in mammalian systems, FEBS Lett., 117, K73, 10.1016/0014-5793(80)80572-2

Williamson, 1981, Role of calcium in the hormonal-regulation of liver-metabolism, Biochim. Biophys. Acta, 639, 243, 10.1016/0304-4173(81)90012-4

Fiskum, 1980, The mechanisms and regulation of mitochondrial Ca2+ transport, Fed. Proc., 39, 2432

Nicholls, 1982, Mitochondrial calcium-transport, Biochim. Biophys. Acta, 683, 57, 10.1016/0304-4173(82)90013-1

Fisher, 1973, Respiration of rat lung mitochondria and influence of Ca2+ on substrate utilization, Biochemistry, 12, 1438, 10.1021/bi00731a026

Wernette, 1981, Ca2+ stimulation of rat-liver mitochondrial glycerophosphate dehydrogenase, J. Biol. Chem., 256, 2767, 10.1016/S0021-9258(18)42961-4

Rutter, 1992, Regulation of mitochondrial glycerol-phosphate dehydrogenase by Ca-2+ within electropermeabilized insulin-secreting cells (Ins-1), Biochim. Biophys. Acta, 1175, 107, 10.1016/0167-4889(92)90016-5

Macdonald, 1996, Calcium activation of mitochondrial glycerol phosphate dehydrogenase restudied, Arch. Biochem. Biophys., 326, 79, 10.1006/abbi.1996.0049

Cole, 1978, Isolation and characterization of flavin-linked glycerol-3-phosphate dehydrogenase from rabbit skeletal-muscle mitochondria and comparison with enzyme from rabbit brain, J. Biol. Chem., 253, 7952, 10.1016/S0021-9258(17)34463-0

Garrib, 1986, Purification and characterization of glycerol-3-phosphate dehydrogenase (flavin-linked) from rat-liver mitochondria, J. Biol. Chem., 261, 8042, 10.1016/S0021-9258(19)57509-3

Brown, 1994, Sequence of rat mitochondrial glycerol-3-phosphate dehydrogenase cDNA — evidence for eF-hand calcium-binding domains, J. Biol. Chem., 269, 14363, 10.1016/S0021-9258(17)36629-2

Persechini, 1989, The eF-hand family of calcium-modulated proteins, Trends Neurosci., 12, 462, 10.1016/0166-2236(89)90097-0

Marsden, 1990, Calcium-binding proteins — elucidating the contributions to calcium affinity from an analysis of species variants and peptide-fragments, Biochem. Cell. Biol.-Biochimie Et Biologie Cellulaire, 68, 587, 10.1139/o90-084

Gifford, 2007, Structures and metal-ion-binding properties of the Ca2+-binding helix–loop–helix ef-hand motifs, Biochem. J., 405, 199, 10.1042/BJ20070255

Ronnow, 1993, Gut2, a gene for mitochondrial glycerol 3-phosphate dehydrogenase of Saccharomyces-cerevisiae, Yeast, 9, 1121, 10.1002/yea.320091013

Shen, 2003, Identification of a mitochondrial glycerol-3-phosphate dehydrogenase from Arabidopsis thaliana: evidence for a mitochondrial glycerol-3-phosphate shuttle in plants, FEBS Lett., 536, 92, 10.1016/S0014-5793(03)00033-4

Hiromasa, 2004, Organization of the cores of the mammalian pyruvate dehydrogenase complex formed by E2 and E2 plus the E3-binding protein and their capacities to bind the E1 and E3 components, J. Biol. Chem., 279, 6921, 10.1074/jbc.M308172200

Reed, 2001, A trail of research from lipoic acid to alpha-keto acid dehydrogenase complexes, J. Biol. Chem., 276, 38329, 10.1074/jbc.R100026200

Randle, 1995, Metabolic fuel selection — general integration at the whole-body level, Proc. Nutr. Soc., 54, 317, 10.1079/PNS19950057

Denton, 1996, The hormonal regulation of pyruvate dehydrogenase complex, Adv. Enzyme Regul., Vol 36, 183, 10.1016/0065-2571(95)00020-8

Uhlinger, 1986, Phosphorylation dephosphorylation of pyruvate-dehydrogenase from bakers-yeast, Biochemistry, 25, 5673, 10.1021/bi00367a049

Karpova, 2003, Characterization of the isozymes of pyruvate dehydrogenase phosphatase: implications for the regulation of pyruvate dehydrogenase activity, Biochimica Et Biophysica Acta. Proteins and Proteomics, 1652, 126, 10.1016/j.bbapap.2003.08.010

Leblanc, 2008, Skeletal muscle type comparison of pyruvate dehydrogenase phosphatase activity and isoform expression: effects of obesity and endurance training, Am. J. Physiol.-Regulatory Integrative and Comparative Physiology, 295, R1224, 10.1152/ajpregu.90320.2008

Huang, 1998, Isoenzymes of pyruvate dehydrogenase phosphatase — DNA-derived amino acid sequences, expression, and regulation, J. Biol. Chem., 273, 17680, 10.1074/jbc.273.28.17680

Teague, 1982, Purification and properties of pyruvate-dehydrogenase phosphatase from bovine heart and kidney, Biochemistry, 21, 5585, 10.1021/bi00265a031

Turkan, 2004, Formation of a complex of the catalytic subunit of pyruvate dehydrogenase phosphatase isoform 1 (Pdp1c) and the L2 domain forms a Ca2+ binding site and captures Pdp1c as a monomer, Biochemistry, 43, 15073, 10.1021/bi048901y

Lawson, 1993, Molecular-cloning and expression of the catalytic subunit of bovine pyruvate-dehydrogenase phosphatase and sequence similarity with protein phosphatase-2c, Biochemistry, 32, 8987, 10.1021/bi00086a002

Chen, 1996, Activated function of the pyruvate dehydrogenase phosphatase through Ca2+-facilitated binding to the inner lipoyl domain of the dihydrolipoyl acetyltransferase, J. Biol. Chem., 271, 28064, 10.1074/jbc.271.45.28064

Turkan, 2002, Structural requirements within the lipoyl domain for the Ca2+-dependent binding and activation of pyruvate dehydrogenase phosphatase isoform 1 or its catalytic subunit, J. Biol. Chem., 277, 14976, 10.1074/jbc.M108434200

Vassylyev, 2007, Crystal structure of pyruvate dehydrogenase phosphatase 1 and its functional implications, J. Mol. Biol., 370, 417, 10.1016/j.jmb.2007.05.002

Denton, 1980, Role of calcium-ions in the regulation of intra-mitochondrial metabolism — effects of Na+, Mg-2+ and ruthenium red on the Ca-2+-stimulated oxidation of oxoglutarate and on pyruvate-dehydrogenase activity in intact rat-heart mitochondria, Biochem. J., 190, 107, 10.1042/bj1900107

Hansford, 1981, Effect of micromolar concentrations of free Ca-2+ ions on pyruvate-dehydrogenase interconversion in intact rat-heart mitochondria, Biochem. J., 194, 721, 10.1042/bj1940721

McCormack, 1985, Characterization of the effects of Ca-2+ on the intramitochondrial Ca-2+-sensitive enzymes from rat-liver and within intact rat-liver mitochondria, Biochem. J., 231, 581, 10.1042/bj2310581

Marshall, 1984, Role of Ca-2+ ions in the regulation of intramitochondrial metabolism in rat epididymal adipose-tissue — evidence against a role for Ca-2+ in the activation of pyruvate-dehydrogenase by insulin, Biochem. J., 218, 249, 10.1042/bj2180249

Hansford, 1985, Role of Ca-2+ in pyruvate-dehydrogenase interconversion in brain mitochondria and synaptosomes, Biochem. J., 227, 129, 10.1042/bj2270129

McCormack, 1988, Characterization of the effects of Ca-2+ on the intramitochondrial Ca-2+-sensitive dehydrogenases within intact rat-kidney mitochondria, Biochim. Biophys. Acta, 934, 282, 10.1016/0005-2728(88)90088-6

Yan, 1996, Role of the regulatory subunit of bovine pyruvate dehydrogenase phosphatase, Proc. Natl. Acad. Sci. U. S. A., 93, 4953, 10.1073/pnas.93.10.4953

Rutter, 1990, Measurement of matrix free Mg-2+ concentration in rat-heart mitochondria by using entrapped fluorescent-probes, Biochem. J., 271, 627, 10.1042/bj2710627

Denton, 1988, The role of Ca-2+ in the hormonal-control of intramitochondrial metabolism in heart, liver, and adipose-tissue, Adv. Second Messenger Phosphoprot. Res., 21, 157

Krause-Buchholz, 2006, Yil042c and Yor090c encode the kinase and phosphatase of the Saccharomyces cerevisiae pyruvate dehydrogenase complex, FEBS Lett., 580, 2553, 10.1016/j.febslet.2006.04.002

Gey, 2008, Yeast pyruvate dehydrogenase complex is regulated by a concerted activity of two kinases and two phosphatases, J. Biol. Chem., 283, 9759, 10.1074/jbc.M708779200

Tovar-Mendez, 2003, Regulation of pyruvate dehydrogenase complex activity in plant cells, Eur. J. Biochem., 270, 1043, 10.1046/j.1432-1033.2003.03469.x

Patel, 2006, Regulation of the pyruvate dehydrogenase complex, Biochem. Soc. Trans., 34, 217, 10.1042/BST0340217

Ehrlich, 1983, Separation, recombination, and characterization of dissimilar subunits of the Dpn-dependent isocitrate dehydrogenase from pig-heart, J. Biol. Chem., 258, 7079, 10.1016/S0021-9258(18)32335-4

Ramachandran, 1980, Chemical characterization of distinct subunits of pig-heart dpn-specific isocitrate dehydrogenase, J. Biol. Chem., 255, 8859, 10.1016/S0021-9258(18)43581-8

Nichols, 1993, Molecular-cloning and deduced amino-acid-sequences of the gamma-subunits of rat and monkey NAD(+)-isocitrate dehydrogenases, Biochem. J., 295, 347, 10.1042/bj2950347

Nichols, 1995, Molecular-cloning and deduced amino-acid-sequences of the alpha- and beta-subunits of mammalian NAD(+)-isocitrate dehydrogenase, Biochem. J., 310, 917, 10.1042/bj3100917

Kim, 1995, Characterization of a cDNA clone for human NAD(+)-specific isocitrate dehydrogenase alpha-subunit and structural comparison with its isoenzymes from different species, Biochem. J., 308, 63, 10.1042/bj3080063

Soundar, 2006, Identification of Mn2+-binding aspartates from alpha, beta, and gamma subunits of human Nad-dependent isocitrate dehydrogenase, J. Biol. Chem., 281, 21073, 10.1074/jbc.M602956200

Bzymek, 2007, Role of alpha-Asp(181), beta-Asp(192), and gamma-Asp(190) in the distinctive subunits of human Nad-specific isocitrate dehydrogenase, Biochemistry, 46, 5391, 10.1021/bi700061t

Taylor, 2008, Allosteric motions in structures of yeast NAD(+)-specific isocitrate dehydrogenase, J. Biol. Chem., 283, 10872, 10.1074/jbc.M708719200

Rutter, 1988, Regulation of NAD+-linked isocitrate dehydrogenase and 2-oxoglutarate dehydrogenase by Ca-2+ ions within toluene-permeabilized rat-heart mitochondria — interactions with regulation by adenine-nucleotides and NADH/NAD+ Ratios, Biochem. J., 252, 181, 10.1042/bj2520181

Rutter, 1989, The binding of Ca-2+ ions to pig-heart Nad+-isocitrate dehydrogenase and the 2-oxoglutarate dehydrogenase complex, Biochem. J., 263, 453, 10.1042/bj2630453

McCormack, 1981, A comparative-study of the regulation by Ca-2+ of the activities of the 2-oxoglutarate dehydrogenase complex and Nad+-isocitrate dehydrogenase from a variety of sources, Biochem. J., 196, 619, 10.1042/bj1960619

Nichols, 1994, Comparison of the effects of Ca2+, adenine-nucleotides and pH on the kinetic-properties of mitochondrial NAD(+)-isocitrate dehydrogenase and oxoglutarate dehydrogenase from the yeast Saccharomyces-cerevisiae and rat-heart, Biochem. J., 303, 461, 10.1042/bj3030461

Hoek, 1988, Physiological roles of nicotinamide nucleotide transhydrogenase, Biochem. J., 254, 1, 10.1042/bj2540001

Hartong, 2008, Insights from retinitis pigmentosa into the roles of isocitrate dehydrogenases in the Krebs cycle, Nat. Genet., 40, 1230, 10.1038/ng.223

Smith, 1979, Activities of NAD-specific and NADP-specific isocitrate dehydrogenases in rat-liver mitochondria — studies with d-threo-alpha-methylisocitrate, Eur. J. Biochem., 97, 283, 10.1111/j.1432-1033.1979.tb13113.x

Hansford, 1975, Steady-state concentrations of coenzyme ASH and coenzyme-A thioester, citrate, and isocitrate during tricarboxylate cycle oxidations in rabbit heart-mitochondria, J. Biol. Chem., 250, 8361, 10.1016/S0021-9258(19)40767-9

Sazanov, 1994, Proton-translocating transhydrogenase and NAD-linked and NADP-linked isocitrate dehydrogenases operate in a substrate cycle which contributes to fine regulation of the tricarboxylic-acid cycle activity in mitochondria, FEBS Lett., 344, 109, 10.1016/0014-5793(94)00370-X

Yeaman, 1989, The 2-oxo acid dehydrogenase complexes — recent advances, Biochem. J., 257, 625, 10.1042/bj2570625

McCartney, 1998, Subunit interactions in the mammalian alpha-ketoglutarate dehydrogenase complex. Evidence for direct association of the alpha-ketoglutarate dehydrogenase and dihydrolipoamide dehydrogenase components, J. Biol. Chem., 273, 24158, 10.1074/jbc.273.37.24158

Lawlis, 1981, Regulation of bovine kidney alpha-ketoglutarate dehydrogenase complex by calcium-ion and adenine-nucleotides — effects on S0.5 for alpha-ketoglutarate, Biochemistry, 20, 2512, 10.1021/bi00512a023

Wan, 1989, Regulation of citric-acid cycle by calcium, J. Biol. Chem., 264, 13430, 10.1016/S0021-9258(18)80015-1

McCormack, 1984, Biochem. J., 218, 235, 10.1042/bj2180235

McCormack, 1985, Studies on the activation of rat liver pyruvate dehydrogenase and 2-oxoglutarate dehydrogenase by adrenaline and glucagon. Role of increases in intramitochondrial Ca2+ concentration, Biochem. J., 231, 597, 10.1042/bj2310597

McCormack, 1983, Ruthenium Red inhibits the activation of pyruvate dehydrogenase caused by positive inotropic agents in the perfused rat heart, Biochem. J., 214, 581, 10.1042/bj2140581

Hansford, 1987, Relation between cytosolic free Ca2+ concentration and the control of pyruvate dehydrogenase in isolated cardiac myocytes, Biochem. J., 241, 145, 10.1042/bj2410145

Palmieri, 2001, Citrin and Aralar1 are Ca2+-stimulated aspartate/glutamate transporters in mitochondria, EMBO J., 20, 5060, 10.1093/emboj/20.18.5060

Yamada, 1988, The calcium-binding ATPase inhibitor protein from bovine heart mitochondria purification and properties, J. Biol. Chem., 263, 11498, 10.1016/S0021-9258(18)37985-7

Yamada, 1989, Calcium-binding ATPase inhibitor protein of bovine heart-mitochondria — role in ATP synthesis and effect of Ca-2+, Biochemistry, 28, 9714, 10.1021/bi00451a026

Harris, 1991, Control of mitochondrial ATP synthesis in the heart, Biochem. J., 280, 561, 10.1042/bj2800561

Scholz, 1994, Mitochondrial F1-Atpase activity of canine myocardium — effects of hypoxia and stimulation, Am. J. Physiol., 266, H2396

Davidson, 1989, Inhibition of mitochondrial-matrix inorganic pyrophosphatase by physiological [Ca-2+], and its role in the hormonal-regulation of mitochondrial matrix volume, Biochem. J., 258, 817, 10.1042/bj2580817

Halestrap, 1989, The regulation of the matrix volume of mammalian mitochondria in vivo and in vitro and its role in the control of mitochondrial metabolism, Biochim. Biophys. Acta, 973, 355, 10.1016/S0005-2728(89)80378-0

Halestrap, 2009, Mitochondrial calcium in health and disease, Biochim. Biophys. Acta, 1787, 1289, 10.1016/j.bbabio.2009.07.011

Csordás, 2009, SR/ER-mitochondrial local communication: Calcium and ROS, Biochim. Biophys. Acta, 1787, 1352, 10.1016/j.bbabio.2009.06.004

Ghafourifar, 1997, Nitric oxide synthase activity in mitochondria, FEBS Lett., 418, 291, 10.1016/S0014-5793(97)01397-5

Solien, 2005, Differential requirements of calcium for oxoglutarate dehydrogenase and mitochondrial nitric-oxide synthase under hypoxia: impact on the regulation of mitochondrial oxygen consumption, Comp. Biochem. Physiol., Part A Mol. Integr. Physiol., 142, 111, 10.1016/j.cbpb.2005.05.004

B. Nichols. Molecular regulation of NAD-isocitrate dehydrogenase, PhD Thesis University of Bristol., (1995).

Rowan, 1979, Changes in the contents of adenine-nucleotides and intermediates of glycolysis and the citric-acid cycle in flight-muscle of the locust upon flight and their relationship to the control of the cycle, Biochem. J., 178, 209, 10.1042/bj1780209