Regulation of innate immune functions by guanylate-binding proteins
Tài liệu tham khảo
Abdullah, 2010, Dimerization and its role in GMP formation by human guanylate binding proteins, Biophys. J., 99, 2235, 10.1016/j.bpj.2010.07.025
Abella, 2016, A WUR SNP is associated with European Porcine Reproductive and Respiratory Virus Syndrome resistance and growth performance in pigs, Res. Vet. Sci., 104, 117, 10.1016/j.rvsc.2015.12.014
Al-Zeer, 2009, IFN-gamma-inducible Irga6 mediates host resistance against Chlamydia trachomatis via autophagy, PLoS One, 4, e4588, 10.1371/journal.pone.0004588
Al-Zeer, 2013, Autophagy restricts Chlamydia trachomatis growth in human macrophages via IFNG-inducible guanylate binding proteins, Autophagy, 9, 50, 10.4161/auto.22482
Alaganan, 2014, Toxoplasma GRA7 effector increases turnover of immunity-related GTPases and contributes to acute virulence in the mouse, Proc. Natl. Acad. Sci. U. S. A., 111, 1126, 10.1073/pnas.1313501111
Anderson, 1999, Interferon-induced guanylate binding protein-1 (GBP-1) mediates an antiviral effect against vesicular stomatitis virus and encephalomyocarditis virus, Virology, 256, 8, 10.1006/viro.1999.9614
Balasubramanian, 2011, Role of GTP binding, isoprenylation, and the C-terminal α-helices in the inhibition of cell spreading by the interferon-induced GTPase, mouse guanylate-binding protein-2, J. Interferon Cytokine Res., 31, 291, 10.1089/jir.2010.0056
Behnke, 2012, The polymorphic pseudokinase ROP5 controls virulence in Toxoplasma gondii by regulating the active kinase ROP18, PLoS Pathog., 8, e1002992, 10.1371/journal.ppat.1002992
Bekpen, 2005, The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage, Genome Biol., 6, R92, 10.1186/gb-2005-6-11-r92
Bekpen, 2009, Death and resurrection of the human IRGM gene, PLoS Genet., 5, e1000403, 10.1371/journal.pgen.1000403
Biering, 2017, Viral replication complexes are targeted by LC3-Guided interferon-Inducible GTPases, Cell Host Microbe, 22, 74, 10.1016/j.chom.2017.06.005
Boddicker, 2012, Evidence for a major QTL associated with host response to porcine reproductive and respiratory syndrome virus challenge, J. Anim. Sci., 90, 1733, 10.2527/jas.2011-4464
Boehm, 1998, Two families of GTPases dominate the complex cellular response to IFN-gamma, J. Immunol., 161, 6715, 10.4049/jimmunol.161.12.6715
Britzen-Laurent, 2010, Intracellular trafficking of guanylate-binding proteins is regulated by heterodimerization in a hierarchical manner, PLoS One, 5, e14246, 10.1371/journal.pone.0014246
Britzen-Laurent, 2016, Pathophysiological role of guanylate-binding proteins in gastrointestinal diseases, World J. Gastroenterol., 22, 6434, 10.3748/wjg.v22.i28.6434
Carlow, 1995, 1995 Isolation of a gene encoding a developmentally regulated T cell-specific protein with a guanine nucleotide triphosphate-binding motif, J. Immunol., 154, 1724, 10.4049/jimmunol.154.4.1724
Carter, 2005, Inhibition of VSV and EMCV replication by the interferon-induced GTPase, mGBP-2: differential requirement for wild-type GTP binding domain, Arch. Virol., 150, 1213, 10.1007/s00705-004-0489-2
Chauhan, 2016, Mechanism of action of the tuberculosis and Crohn disease risk factor IRGM in autophagy, Autophagy, 12, 429, 10.1080/15548627.2015.1084457
Cheng, 1983, Interferon induction of fibroblast proteins with guanylate binding activity, J. Biol. Chem., 258, 7746, 10.1016/S0021-9258(18)32242-7
Cheng, 1991, Interferon-induced guanylate-binding proteins lack an N(T)KXD consensus motif and bind GMP in addition to GDP and GTP, Mol. Cell. Biol., 11, 4717, 10.1128/MCB.11.9.4717
Choi, 2014, The parasitophorous vacuole membrane of Toxoplasma gondii is targeted for disruption by ubiquitin-like conjugation systems of autophagy, Immunity, 40, 924, 10.1016/j.immuni.2014.05.006
Clough, 2017, The toxoplasma parasitophorous vacuole: an evolving host-Parasite frontier, Trends Parasitol., 33, 473, 10.1016/j.pt.2017.02.007
Coers, 2011, Compensatory T cell responses in IRG-deficient mice prevent sustained Chlamydia trachomatis infections, PLoS Pathog., 7, e1001346, 10.1371/journal.ppat.1001346
Darnell, 1994, Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins, Science, 264, 1415, 10.1126/science.8197455
Daumke, 2016, Invited review: mechanisms of GTP hydrolysis and conformational transitions in the dynamin superfamily, Biopolymers, 105, 580, 10.1002/bip.22855
Degrandi, 2007, 2007 Extensive characterization of IFN-induced GTPases mGBP1 to mGBP10 involved in host defense, J. Immunol., 179, 7729, 10.4049/jimmunol.179.11.7729
Degrandi, 2013, Murine guanylate binding protein 2 (mGBP2) controls Toxoplasma gondii replication, Proc. Natl. Acad. Sci. U. S. A., 110, 294, 10.1073/pnas.1205635110
Etheridge, 2014, The Toxoplasma pseudokinase ROP5 forms complexes with ROP18 and ROP17 kinases that synergize to control acute virulence in mice, Cell Host Microbe, 15, 537, 10.1016/j.chom.2014.04.002
Ewald, 2014, NLRP1 is an inflammasome sensor for Toxoplasma gondii, Infect. Immun., 82, 460, 10.1128/IAI.01170-13
Feeley, 2017, Galectin-3 directs antimicrobial guanylate binding proteins to vacuoles furnished with bacterial secretion systems, Proc. Natl. Acad. Sci. U. S. A., 114, E1698, 10.1073/pnas.1615771114
Fellenberg, 2004, GBP-5 splicing variants: new guanylate-binding proteins with tumor-associated expression and antigenicity, J. Invest. Dermatol., 122, 1510, 10.1111/j.0022-202X.2004.22613.x
Feng, 2008, The p47 GTPase Lrg-47(Irgm1) links host defense and hematopoietic stem cell proliferation, Cell Stem Cell, 2, 83, 10.1016/j.stem.2007.10.007
Feng, 2017, Inducible GBP5 mediates the antiviral response via interferon-Related pathways during influenza a virus infection, J. Innate Immun., 9, 419, 10.1159/000460294
Fentress, 2010, Phosphorylation of immunity-related GTPases by a Toxoplasma gondii-secreted kinase promotes macrophage survival and virulence, Cell Host Microbe, 8, 484, 10.1016/j.chom.2010.11.005
Fiegl, 2013, 2013 Amphisomal route of MHC class I cross-presentation in bacteria-infected dendritic cells, J. Immunol., 190, 2791, 10.4049/jimmunol.1202741
Finethy, 2015, Guanylate binding proteins enable rapid activation of canonical and noncanonical inflammasomes in Chlamydia-infected macrophages, Infect. Immun., 83, 4740, 10.1128/IAI.00856-15
Finethy, 2017, Inflammasome activation by bacterial outer membrane vesicles requires guanylate binding proteins, mBio, 8, 10.1128/mBio.01188-17
Fleckenstein, 2012, A Toxoplasma gondii pseudokinase inhibits host IRG resistance proteins, PLoS Biol., 10, e1001358, 10.1371/journal.pbio.1001358
Foltz, 2017, TRIM21 is critical for survival of Toxoplasma gondii infection and localises to GBP-positive parasite vacuoles, Sci. Rep., 7, 5209, 10.1038/s41598-017-05487-7
Fox, 2004, Toxoplasma gondii lacks the enzymes required for de novo arginine biosynthesis and arginine starvation triggers cyst formation, Int. J. Parasitol., 34, 323, 10.1016/j.ijpara.2003.12.001
Fres, 2010, Purification of the CaaX-modified, dynamin-related large GTPase hGBP1 by coexpression with farnesyltransferase, J. Lipid Res., 51, 2454, 10.1194/jlr.D005397
Ghosh, 2004, Crystal structure of IIGP1: a paradigm for interferon-inducible p47 resistance GTPases, Mol. Cell, 15, 727, 10.1016/j.molcel.2004.07.017
Ghosh, 2006, How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP, Nature, 440, 101, 10.1038/nature04510
Gilly, 1992, 1992 The IRG-47 gene is IFN-gamma induced in B cells and encodes a protein with GTP-binding motifs, J. Immunol., 148, 3275, 10.4049/jimmunol.148.10.3275
Gorfu, 2014, Dual role for inflammasome sensors NLRP1 and NLRP3 in murine resistance to Toxoplasma gondii, mBio, 5, 10.1128/mBio.01117-13
Guenzi, 2001, The helical domain of GBP-1 mediates the inhibition of endothelial cell proliferation by inflammatory cytokines, EMBO J., 20, 5568, 10.1093/emboj/20.20.5568
Haldar, 2013, IRG and GBP host resistance factors target aberrant, non-self vacuoles characterized by the missing of self IRGM proteins, PLoS Pathog., 9, e1003414, 10.1371/journal.ppat.1003414
Haldar, 2014, The E2-like conjugation enzyme Atg3 promotes binding of IRG and Gbp proteins to Chlamydia- and Toxoplasma-containing vacuoles and host resistance, PLoS One, 9, e86684, 10.1371/journal.pone.0086684
Haldar, 2015, Ubiquitin systems mark pathogen-containing vacuoles as targets for host defense by guanylate binding proteins, Proc. Natl. Acad. Sci. U. S. A., 112, E5628, 10.1073/pnas.1515966112
Haldar, 2016, Chlamydia trachomatis is resistant to inclusion ubiquitination and associated host defense in gamma interferon-Primed human epithelial cells, mBio, 7, 10.1128/mBio.01417-16
Haller, 2015, Mx GTPases: dynamin-like antiviral machines of innate immunity, Trends Microbiol., 23, 154, 10.1016/j.tim.2014.12.003
Hermanns, 2016, The Toxoplasma gondii rhoptry protein ROP18 is an Irga6-specific kinase and regulated by the dense granule protein GRA7, Cell. Microbiol., 18, 244, 10.1111/cmi.12499
Howard, 2011, The IRG protein-based resistance mechanism in mice and its relation to virulence in Toxoplasma gondii, Curr. Opin. Microbiol., 14, 414, 10.1016/j.mib.2011.07.002
Hu, 2016, Fusion of the endoplasmic reticulum by membrane-bound GTPases, Semin. Cell Dev. Biol., 60, 105, 10.1016/j.semcdb.2016.06.001
Hunn, 2008, Regulatory interactions between IRG resistance GTPases in the cellular response to Toxoplasma gondii, EMBO J., 27, 2495, 10.1038/emboj.2008.176
Ince, 2017, The human guanylate-binding proteins hGBP-1 and hGBP-5 cycle between monomers and dimers only, FEBS J., 284, 2284, 10.1111/febs.14126
Itsui, 2009, Antiviral effects of the interferon-induced protein guanylate binding protein 1 and its interaction with the hepatitis C virus NS5B protein, Hepatology, 50, 1727, 10.1002/hep.23195
Johnston, 2016, Human GBP1 does not localize to pathogen vacuoles but restricts Toxoplasma gondii, Cell. Microbiol., 18, 1056, 10.1111/cmi.12579
Jutras, 2008, Modulation of the phagosome proteome by interferon-gamma, Mol. Cell. Proteomics, 7, 697, 10.1074/mcp.M700267-MCP200
Khaminets, 2010, Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole, Cell. Microbiol., 12, 939, 10.1111/j.1462-5822.2010.01443.x
Kim, 2011, A family of IFN- −Inducible 65-kD GTPases protects against bacterial infection, Science, 332, 717, 10.1126/science.1201711
Kim, 2016, Interferon-induced guanylate-binding proteins in inflammasome activation and host defense, Nat. Immunol., 17, 481, 10.1038/ni.3440
King, 2011, Irgm1 protects hematopoietic stem cells by negative regulation of IFN signaling, Blood, 118, 1525, 10.1182/blood-2011-01-328682
Koltes, 2015, Identification of a putative quantitative trait nucleotide in guanylate binding protein 5 for host response to PRRS virus infection, BMC Genomics, 16, 412, 10.1186/s12864-015-1635-9
Kommadath, 2017, Genetic architecture of gene expression underlying variation in host response to porcine reproductive and respiratory syndrome virus infection, Sci. Rep., 7, 46203, 10.1038/srep46203
Krapp, 2016, Guanylate binding protein (GBP) 5 is an interferon-Inducible inhibitor of HIV-1 infectivity, Cell Host Microbe, 19, 504, 10.1016/j.chom.2016.02.019
Kravets, 2012, The GTPase activity of murine guanylate-binding protein 2 (mGBP2) controls the intracellular localization and recruitment to the parasitophorous vacuole of Toxoplasma gondii, J. Biol. Chem., 287, 27452, 10.1074/jbc.M112.379636
Kravets, 2016, Guanylate binding proteins directly attack Toxoplasma gondii via supramolecular complexes, eLife, 5
Kresse, 2008, Analyses of murine GBP homology clusters based on in silico, in vitro and in vivo studies, BMC Genomics, 9, 158, 10.1186/1471-2164-9-158
Kunzelmann, 2006, Transient kinetic investigation of GTP hydrolysis catalyzed by interferon-gamma-induced hGBP1 (human guanylate binding protein 1), J. Biol. Chem., 281, 28627, 10.1074/jbc.M604911200
Lafuse, 1995, Cloning and characterization of a novel cDNA that is IFN-gamma-induced in mouse peritoneal macrophages and encodes a putative GTP-binding protein, J. Leukoc. Biol., 57, 477, 10.1002/jlb.57.3.477
Lee, 2015, P62 plays a specific role in interferon-γ-Induced presentation of a toxoplasma vacuolar antigen, Cell Rep., 13, 223, 10.1016/j.celrep.2015.09.005
Lew, 1991, Overlapping elements in the guanylate-binding protein gene promoter mediate transcriptional induction by alpha and gamma interferons, Mol. Cell. Biol., 11, 182, 10.1128/MCB.11.1.182
Li, 2009, The evolutionarily dynamic IFN-inducible GTPase proteins play conserved immune functions in vertebrates and cephalochordates, Mol. Biol. Evol., 26, 1619, 10.1093/molbev/msp074
Li, 2016, Guanylate-Binding protein 1, an interferon-Induced GTPase, exerts an antiviral activity against classical swine fever virus depending on its GTPase activity, J. Virol., 90, 4412, 10.1128/JVI.02718-15
Lilue, 2013, Reciprocal virulence and resistance polymorphism in the relationship between Toxoplasma gondii and the house mouse, eLife, 2, e01298, 10.7554/eLife.01298
Lindenberg, 2017, Broad recruitment of mGBP family members to Chlamydia trachomatis inclusions, PLoS One, 12, e0185273, 10.1371/journal.pone.0185273
MacMicking, 2012, Interferon-inducible effector mechanisms in cell-autonomous immunity. Nature reviews, Immunology, 12, 367
Man, 2016, IRGB10 liberates bacterial ligands for sensing by the AIM2 and caspase-11-NLRP3 inflammasomes, Cell, 167, 382, 10.1016/j.cell.2016.09.012
Maric-Biresev, 2016, Loss of the interferon-γ-inducible regulatory immunity-related GTPase (IRG), Irgm1, causes activation of effector IRG proteins on lysosomes, damaging lysosomal function and predicting the dramatic susceptibility of Irgm1-deficient mice to infection, BMC Biol., 14, 33, 10.1186/s12915-016-0255-4
Martens, 2004, Mechanisms regulating the positioning of mouse p47 resistance GTPases LRG-47 and IIGP1 on cellular membranes: retargeting to plasma membrane induced by phagocytosis, J. Immunol., 173, 2594, 10.4049/jimmunol.173.4.2594
McNew, 2013, GTP-dependent membrane fusion, Annu. Rev. Cell Dev. Biol., 29, 529, 10.1146/annurev-cellbio-101512-122328
Meunier, 2015, Interferon-induced guanylate-binding proteins promote cytosolic lipopolysaccharide detection by caspase-11, DNA Cell Biol., 34, 1, 10.1089/dna.2014.2701
Meunier, 2016, Interferon-inducible GTPases in cell autonomous and innate immunity, Cell. Microbiol., 18, 168, 10.1111/cmi.12546
Meunier, 2014, Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases, Nature, 509, 366, 10.1038/nature13157
Modiano, 2005, Golgi targeting of human guanylate-binding protein-1 requires nucleotide binding, isoprenylation, and an IFN-gamma-inducible cofactor, Proc. Natl. Acad. Sci. U. S. A., 102, 8680, 10.1073/pnas.0503227102
Mordue, 1999, Invasion by Toxoplasma gondii establishes a moving junction that selectively excludes host cell plasma membrane proteins on the basis of their membrane anchoring, J. Exp. Med., 190, 1783, 10.1084/jem.190.12.1783
Nantais, 1996, Prenylation of an interferon-gamma-induced GTP-binding protein: the human guanylate binding protein, huGBP1, J. Leukoc. Biol., 60, 423, 10.1002/jlb.60.3.423
Naschberger, 2017, Processing and secretion of guanylate binding protein-1 depend on inflammatory caspase activity, J. Cell. Mol. Med., 21, 1954, 10.1111/jcmm.13116
Neun, 1996, GTPase properties of the interferon-induced human guanylate-binding protein 2, FEBS Lett., 390, 69, 10.1016/0014-5793(96)00628-X
Niedelman, 2012, The rhoptry proteins ROP18 and ROP5 mediate Toxoplasma gondii evasion of the murine, but not the human, interferon-gamma response, PLoS Pathog., 8, e1002784, 10.1371/journal.ppat.1002784
Niedelman, 2013, Cell death of gamma interferon-stimulated human fibroblasts upon Toxoplasma gondii infection induces early parasite egress and limits parasite replication, Infect. Immun., 81, 4341, 10.1128/IAI.00416-13
Niu, 2016, Effect of polymorphisms in the GBP1, Mx1 and CD163 genes on host responses to PRRSV infection in pigs, Vet. Microbiol., 182, 187, 10.1016/j.vetmic.2015.11.010
Nordmann, 2012, A new splice variant of the human guanylate-binding protein 3 mediates anti-influenza activity through inhibition of viral transcription and replication, FASEB J., 26, 1290, 10.1096/fj.11-189886
Obar, 1990, Molecular cloning of the microtubule-associated mechanochemical enzyme dynamin reveals homology with a new family of GTP-binding proteins, Nature, 347, 256, 10.1038/347256a0
Ohshima, 2014, Role of mouse and human autophagy proteins in IFN-γ-induced cell-autonomous responses against Toxoplasma gondii, J. Immunol., 192, 3328, 10.4049/jimmunol.1302822
Ohshima, 2015, RabGDIα is a negative regulator of interferon-γ-inducible GTPase-dependent cell-autonomous immunity to Toxoplasma gondii, Proc. Natl. Acad. Sci. U. S. A., 112, E4581, 10.1073/pnas.1510031112
Olszewski, 2006, In silico genomic analysis of the human and murine guanylate-binding protein (GBP) gene clusters, J. Interferon Cytokine Res., 26, 328, 10.1089/jir.2006.26.328
Ostler, 2014, Gamma interferon-induced guanylate binding protein 1 is a novel actin cytoskeleton remodeling factor, Mol. Cell. Biol., 34, 196, 10.1128/MCB.00664-13
Pan, 2012, Guanylate-binding protein 1 participates in cellular antiviral response to dengue virus, Virol. J., 9, 292, 10.1186/1743-422X-9-292
Pandita, 2016, Tetrameric assembly of hGBP1 is crucial for both stimulated GMP formation and antiviral activity, Biochem. J., 473, 1745, 10.1042/BCJ20160220
Papic, 2008, Inactive and active states of the interferon-inducible resistance GTPase, Irga6, in vivo, J. Biol. Chem., 283, 32143, 10.1074/jbc.M804846200
Pawlowski, 2011, The activation mechanism of Irga6, an interferon-inducible GTPase contributing to mouse resistance against Toxoplasma gondii, BMC Biol., 9, 7, 10.1186/1741-7007-9-7
Pfefferkorn, 1986, Characterization of an indoleamine 2,3-dioxygenase induced by gamma-interferon in cultured human fibroblasts, J. Interferon Res., 6, 267, 10.1089/jir.1986.6.267
Pfefferkorn, 1984, Interferon gamma blocks the growth of Toxoplasma gondii in human fibroblasts by inducing the host cells to degrade tryptophan, Proc. Natl. Acad. Sci. U. S. A., 81, 908, 10.1073/pnas.81.3.908
Pilla, 2014, Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS, Proc. Natl. Acad. Sci. U. S. A., 111, 6046, 10.1073/pnas.1321700111
Pilla-Moffett, 2016, Interferon-Inducible GTPases in host resistance, inflammation and disease, J. Mol. Biol., 428, 3495, 10.1016/j.jmb.2016.04.032
Platanias, 2005, Mechanisms of type-I- and type-II-interferon-mediated signalling, Nat. Rev. Immunol., 5, 375, 10.1038/nri1604
Praefcke, 2004, The dynamin superfamily: universal membrane tubulation and fission molecules?, Nat. Rev. Mol. Cell Biol., 5, 133, 10.1038/nrm1313
Praefcke, 1999, Nucleotide-binding characteristics of human guanylate-binding protein 1 (hGBP1) and identification of the third GTP-binding motif, J. Mol. Biol., 292, 321, 10.1006/jmbi.1999.3062
Praefcke, 2004, Identification of residues in the human guanylate-binding protein 1 critical for nucleotide binding and cooperative GTP hydrolysis, J. Mol. Biol., 344, 257, 10.1016/j.jmb.2004.09.026
Prakash, 2000, Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteins, Nature, 403, 567, 10.1038/35000617
Prakash, 2000, Triphosphate structure of guanylate-binding protein 1 and implications for nucleotide binding and GTPase mechanism, EMBO J., 19, 4555, 10.1093/emboj/19.17.4555
Qin, 2017, Guanylate-binding protein 1 (GBP1) contributes to the immunity of human mesenchymal stromal cells against Toxoplasma gondii, Proc. Natl. Acad. Sci. U. S. A., 114, 1365, 10.1073/pnas.1619665114
Scharton-Kersten, 1997, Inducible nitric oxide is essential for host control of persistent but not acute infection with the intracellular pathogen Toxoplasma gondii, J. Exp. Med., 185, 1261, 10.1084/jem.185.7.1261
Schnoor, 2009, Guanylate-binding protein-1 is expressed at tight junctions of intestinal epithelial cells in response to interferon-gamma and regulates barrier function through effects on apoptosis, Mucosal Immunol., 2, 33, 10.1038/mi.2008.62
Schroyen, 2016, Bioinformatic analyses in early host response to Porcine Reproductive and Respiratory Syndrome virus (PRRSV) reveals pathway differences between pigs with alternate genotypes for a major host response QTL, BMC Genomics, 17, 196, 10.1186/s12864-016-2547-z
Schulte, 2016, The immunity-related GTPase Irga6 dimerizes in a parallel head-to-head fashion, BMC Biol., 14, 14, 10.1186/s12915-016-0236-7
Schwemmle, 1994, The interferon-induced 67-kDa guanylate-binding protein (hGBP1) is a GTPase that converts GTP to GMP, J. Biol. Chem., 269, 11299, 10.1016/S0021-9258(19)78125-3
Selleck, 2013, Guanylate-binding protein 1 (Gbp1) contributes to cell-autonomous immunity against Toxoplasma gondii, PLoS Pathog., 9, e1003320, 10.1371/journal.ppat.1003320
Shenoy, 2012, GBP5 promotes NLRP3 inflammasome assembly and immunity in mammals, Science, 336, 481, 10.1126/science.1217141
Shydlovskyi, 2017, Nucleotide-dependent farnesyl switch orchestrates polymerization and membrane binding of human guanylate-binding protein 1, Proc. Natl. Acad. Sci. U. S. A., 114, E5559, 10.1073/pnas.1620959114
Sorace, 1995, Identification of an endotoxin and IFN-inducible cDNA: possible identification of a novel protein family, J. Leukoc. Biol., 58, 477, 10.1002/jlb.58.4.477
Steinfeldt, 2010, Phosphorylation of mouse immunity-related GTPase (IRG) resistance proteins is an evasion strategy for virulent Toxoplasma gondii, PLoS Biol., 8, e1000576, 10.1371/journal.pbio.1000576
Stickney, 2000, Murine guanylate-binding protein: incomplete geranylgeranyl isoprenoid modification of an interferon-gamma-inducible guanosine triphosphate-binding protein, Mol. Biol. Cell, 11, 2191, 10.1091/mbc.11.7.2191
Syguda, 2012, Tetramerization of human guanylate-binding protein 1 is mediated by coiled-coil formation of the C-terminal α-helices, FEBS J., 279, 2544, 10.1111/j.1742-4658.2012.08637.x
Syguda, 2012, Immobilization of biotinylated hGBP1 in a defined orientation on surfaces is crucial for uniform interaction with analyte proteins and catalytic activity, Langmuir, 28, 6411, 10.1021/la3008359
Taylor, 1996, Identification of a novel GTPase, the inducibly expressed GTPase, that accumulates in response to interferon gamma, J. Biol. Chem., 271, 20399, 10.1074/jbc.271.34.20399
Taylor, 2000, Pathogen-specific loss of host resistance in mice lacking the IFN-gamma-inducible gene IGTP, Proc. Natl. Acad. Sci. U. S. A., 97, 751, 10.1073/pnas.97.2.751
Thurston, 2012, Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion, Nature, 482, 414, 10.1038/nature10744
Tietzel, 2009, Human guanylate binding proteins potentiate the anti-chlamydia effects of interferon-gamma, PLoS One, 4, e6499, 10.1371/journal.pone.0006499
Traver, 2011, Immunity-related GTPase M (IRGM) proteins influence the localization of guanylate-binding protein 2 (GBP2) by modulating macroautophagy, J. Biol. Chem., 286, 30471, 10.1074/jbc.M111.251967
Tripal, 2007, Unique features of different members of the human guanylate-binding protein family, J. Interferon Cytokine Res., 27, 44, 10.1089/jir.2007.0086
Trost, 2009, The phagosomal proteome in interferon-gamma-activated macrophages, Immunity, 30, 143, 10.1016/j.immuni.2008.11.006
Tyrkalska, 2016, Neutrophils mediate Salmonella Typhimurium clearance through the GBP4 inflammasome-dependent production of prostaglandins, Nat. Commun., 7, 12077, 10.1038/ncomms12077
Uthaiah, 2003, IIGP1, an interferon-gamma-inducible 47-kDa GTPase of the mouse, showing cooperative enzymatic activity and GTP-dependent multimerization, J. Biol. Chem., 278, 29336, 10.1074/jbc.M211973200
Vöpel, 2009, Nucleotide dependent cysteine reactivity of hGBP1 uncovers a domain movement during GTP hydrolysis, FEBS Lett., 583, 1923, 10.1016/j.febslet.2009.05.027
Vöpel, 2010, Mechanism of GTPase-activity-induced self-assembly of human guanylate binding protein 1, J. Mol. Biol., 400, 63, 10.1016/j.jmb.2010.04.053
Vöpel, 2014, Triphosphate induced dimerization of human guanylate binding protein 1 involves association of the C-terminal helices: a joint double electron–electron resonance and FRET study, Biochemistry, 53, 4590, 10.1021/bi500524u
Vestal, 2000, Different subcellular localizations for the related interferon-induced GTPases, MuGBP-1 and MuGBP-2: implications for different functions?, Journal Interferon Cytokine Res., 20, 991, 10.1089/10799900050198435
Virreira Winter, 2011, Determinants of GBP recruitment to Toxoplasma gondii vacuoles and the parasitic factors that control it, PLoS One, 6, e24434, 10.1371/journal.pone.0024434
Wallet, 2017, IFN-γ extends the immune functions of Guanylate Binding Proteins to inflammasome-independent antibacterial activities during Francisella novicida infection, PLoS Pathog., 13, e1006630, 10.1371/journal.ppat.1006630
Wandel, 2017, GBPs inhibit motility of shigella flexneri but are targeted for degradation by the bacterial ubiquitin ligase IpaH9. 8, Cell Host Microbe, 22, 507, 10.1016/j.chom.2017.09.007
Wehner, 2010, Biochemical properties of the human guanylate binding protein 5 and a tumor-specific truncated splice variant, FEBS J., 277, 1597, 10.1111/j.1742-4658.2010.07586.x
Wehner, 2012, The guanine cap of human guanylate-binding protein 1 is responsible for dimerization and self-activation of GTP hydrolysis, FEBS J., 279, 203, 10.1111/j.1742-4658.2011.08415.x
Yamamoto, 2012, A cluster of interferon-γ-inducible p65 GTPases plays a critical role in host defense against Toxoplasma gondii, Immunity, 37, 302, 10.1016/j.immuni.2012.06.009
Yarovinsky, 2014, Innate immunity to Toxoplasma gondii infection. Nature reviews, Immunology, 14, 109
Zhao, 2008, Autophagosome-independent essential function for the autophagy protein Atg5 in cellular immunity to intracellular pathogens, Cell Host Microbe, 4, 458, 10.1016/j.chom.2008.10.003
Zhao, 2009, Disruption of the Toxoplasma gondii parasitophorous vacuole by IFNgamma-inducible immunity-related GTPases (IRG proteins) triggers necrotic cell death, PLoS Pathog., 5, e1000288, 10.1371/journal.ppat.1000288
Zou, 2017, Guanylate-Binding protein 1 inhibits nuclear delivery of kaposi's sarcoma-associated herpesvirus virions by disrupting formation of actin filament, J. Virol., 91, 10.1128/JVI.00632-17