Regulation of genes encoding NAD(P)H:quinone oxidoreductases

Free Radical Biology and Medicine - Tập 29 Số 3-4 - Trang 254-262 - 2000
Anil K. Jaiswal1
1Department of Pharmacology, Baylor College of Medicine, Houston, TX, USA

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Tài liệu tham khảo

Monks, 1992, Quinone chemistry and toxicity, Toxicol. Appl. Pharm., 112, 2, 10.1016/0041-008X(92)90273-U

Radjendirane, 1997, Gene expression of DT diaphorase (NQO1) in cancer cells, 441

Ernster, 1958, Soluble diaphorases in animal tissues, Acta Chem. Scand., 12, 595, 10.3891/acta.chem.scand.12-0595

Ernster, 1960, Purification and some properties of a highly dicumarol-sensitive liver diaphorase, Biochem. Biophys. Res. Commun., 2, 88, 10.1016/0006-291X(60)90193-5

Hojeberg, 1981, Biospecific adsorption of hepatic DT diaphorase on immobilized dicumarol, Arch. Biochem. Biophys., 207, 205, 10.1016/0003-9861(81)90026-6

Raftell, 1980, Immunochemical studies on two DT diaphorase–active antigens isolated from rat liver cytosol by affinity chromatography, Arch. Biochem. Biophys., 199, 165, 10.1016/0003-9861(80)90269-6

Segura-Aguilar, 1992, Separation and characterization of isoforms of DT diaphorase from rat liver cytosol, Biochem. Biophys. Acta, 1120, 33, 10.1016/0167-4838(92)90421-9

Prochaska, 1986, Purification and characterization of two isofunctional forms of NAD(P)H:quinone reductase from mouse liver, J. Biol. Chem., 261, 1372, 10.1016/S0021-9258(17)36101-X

Edwards, 1980, Human FAD-dependent NAD(P)H diaphorase, Biochem. J., 187, 429, 10.1042/bj1870429

Shaw, 1991, The human dioxin-inducible NAD(P)H:quinone oxidoreductase cDNA-encoded protein expressed in COS-1 cells is identical to diaphorase 4, Eur. J. Biochem., 195, 171, 10.1111/j.1432-1033.1991.tb15691.x

Wu, 1997, Catalytic properties of NAD(P)H:quinone oxidoreductase 2 (NQO2), a dihydronicotinamide riboside–dependent oxidoreductase, Arch. Biochem. Biophys., 347, 221, 10.1006/abbi.1997.0344

Zhao, 1997, Unexpected genetic and structural relationships of a long-forgotten flavoenzyme to NAD(P)H:quinone reductase (DT diaphorase), Proc. Natl. Acad. Sci. USA, 94, 1669, 10.1073/pnas.94.5.1669

Robertson, 1986, NAD(P)H:menadione oxidoreductase, J. Biol. Chem., 261, 15794, 10.1016/S0021-9258(18)66789-4

Williams, 1986, Rat liver NAD(P)H:quinone reductase, J. Biol. Chem., 261, 5524, 10.1016/S0021-9258(19)57246-5

Bayney, 1989, Rat liver NAD(P)H:quinone reductase, J. Biol. Chem., 264, 21793, 10.1016/S0021-9258(20)88253-2

Jaiswal, 1988, Human dioxin-inducible cytosolic NAD(P)H:quinone oxidoreductase, J. Biol. Chem., 263, 13572, 10.1016/S0021-9258(18)68280-8

Jaiswal, 1991, Human NAD(P)H:quinone oxidoreductase gene structure and induction by dioxin, Biochemistry, 30, 10647, 10.1021/bi00108a007

Ernster, 1987, DT diaphorase, Chem. Scripta, 27A, 1

Fahey, 1995, Chemoprotection against cancer by phase 2 enzyme induction, Toxicol. Lett., 82, 83, 173, 10.1016/0378-4274(95)03553-2

Riley, 1992, DT diaphorase and cancer chemotherapy, Biochem. Pharm., 43, 1657, 10.1016/0006-2952(92)90694-E

Joseph, 1994, NAD(P)H:quinone oxidoreductase 1 (DT diaphorase) specifically prevents the formation of benzo(a)pyrene quinone–DNA adducts generated by cytochrome P4501A1 and P450 reductase, Proc. Natl. Acad. Sci. USA, 91, 8413, 10.1073/pnas.91.18.8413

Lind, 1982, DT diaphorase, 321

Chesis, 1984, Mutagenicity of quinones, Proc. Natl. Acad. Sci. USA, 81, 1696, 10.1073/pnas.81.6.1696

Brunmark, 1988, DT diaphorase catalyzed two-electron reduction of various p-benzoquinone- and 1,4-naphthoquinone epoxides, Free Radic. Biol. Med., 5, 133, 10.1016/0891-5849(88)90076-7

De Flora, 1985, Prominent role of DT diaphorase as a cellular mechanism reducing chromium (VI) and reverting its mutagenicity, Cancer Res, 45, 3188

Hakura, 1994, Mutagenicity and cytotoxicity of naphthoquinones for Ames Salmonella Tester Strains, Chem. Res. Toxicol., 7, 559, 10.1021/tx00040a012

Hakura, 1995, Mutagenicity of benzoquinones for Ames Salmonella Tester Strains, Mutat. Res., 347, 37, 10.1016/0165-7992(95)90031-4

Joseph, 1998, NAD(P)H:quinone oxidoreductase 1 (NQO1) reduces the mutagenicity of DNA caused by NAD(P)H:P450 reductase–activated metabolites of benzo(a)pyrene quinones, Br. J. Canc., 77, 709, 10.1038/bjc.1998.117

Joseph, 1998, Hydroquinones cause specific frame shift mutations involving deletion of a single cytosine from the DNA sequence 5′-CCCCC-3′ and lead to cellular transformation and in vivo tumorigenesis, Br. J. Canc., 78, 312, 10.1038/bjc.1998.492

Radjendirane, 1998, Disruption of the DT diaphorase (NQO1) in mice leads to increased menadione toxicity, J. Biol. Chem., 273, 7382, 10.1074/jbc.273.13.7382

Jaiswal, 1990, Nucleotide and deduced amino acid sequence of a human cDNA (NQO2) corresponding to a second member of the NAD(P)H:quinone oxidoreductase gene family. Extensive polymorphism at the NQO2 gene locus on chromosome 6, Biochemistry, 29, 1899, 10.1021/bi00459a034

Jaiswal, 1994, Human NAD(P)H:quinone oxidoreductase 2, J. Biol. Chem., 269, 14502, 10.1016/S0021-9258(17)36651-6

Jaiswal, 1999, Localization of human NQO1 gene to chromosome 16q22 and NQO2-6p25 and associated polymorphism, Pharmacogenetics, 9, 413, 10.1097/00008571-199906000-00020

Ross, 1994, Bioactivation of quinones by DT diaphorase, molecular, biochemical, and chemical studies, Oncol. Res., 6, 493

Rauth, 1997, DT diaphorase, Oncol. Res., 9, 339

Workman, 1994, Enzyme-directed bioreductive drug development revisted. A commentary on recent progress and future prospects with emphasis on quinone anticancer agents and quinone metabolizing enzymes particularly DT diaphorase, Oncol. Res., 6, 461

Ernster, 1990, DT diaphorase, Meth. Enzymol., 186, 287

Cresteil, 1987, Transcriptional control of human cytochrome P1-450 (CYP 1A1) gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in human tissue culture cell lines, Arch. Biochem. Biophys., 253, 233, 10.1016/0003-9861(87)90656-4

Rushmore, 1993, Glutathione s-transferase structure, regulation, and therapeutic implications, J. Biol. Chem., 268, 11475, 10.1016/S0021-9258(19)50219-8

Nebert, 1994, Drug-metabolizing enzymes in ligand-modulated transcription, Biochem. Pharmacol., 47, 25, 10.1016/0006-2952(94)90434-0

Daniel, 1989, Regulatory elements controlling the basal and drug- inducible expression of glutathione s-transferase Ya subunit gene, DNA, 8, 399, 10.1089/dna.1.1989.8.399

Jaiswal, 1994, Antioxidant response element, Biochem. Pharmacol., 48, 439, 10.1016/0006-2952(94)90272-0

Hayes, 1995, Potential contribution of the glutathione s-transferase supergene family to resistance to oxidative stress, Free Radic. Res., 22, 193, 10.3109/10715769509147539

Pickett, 1989, Glutathione s-transferases, Ann. Rev. Biochem., 58, 743, 10.1146/annurev.bi.58.070189.003523

Tsuchida, 1992, Glutathione transferases and cancer, Crit. Rev. Biochem. Molec. Biol., 27, 337, 10.3109/10409239209082566

Tephly, 1990, UDP-glucuronosyl transferase, Trends Pharm, 11, 276, 10.1016/0165-6147(90)90008-V

Oesch, 1991, 447

Mulkahy, 1997, Constitutive and β-naphthoflavone-induced expression of the human γ-glutamylcysteine synthetase heavy subunit gene is regulated by a distal antioxidant response element/TRE sequence, J. Biol. Chem., 272, 7445, 10.1074/jbc.272.11.7445

Wattenburg, 1983, Inhibition of neoplasia by minor dietary constituents, Cancer Res, 43, 2448s

Wattenburg, 1985, Chemoprevention of cancer, Cancer Res, 45, 1

Zhang, 1992, A major inducer of anticarcinogenic protective enzymes from broccoli, Proc. Natl. Acad. Sci. USA, 89, 2399, 10.1073/pnas.89.6.2399

Zhang, 1994, Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates, Proc. Natl. Acad. Sci. USA, 91, 3147, 10.1073/pnas.91.8.3147

Li, 1992, Regulation of human NAD(P)H:quinone oxidoreductase gene, J. Biol. Chem., 267, 15097, 10.1016/S0021-9258(18)42151-5

Xie, 1995, ARE- and TRE-mediated regulation of gene expression, J. Biol. Chem., 270, 6894, 10.1074/jbc.270.12.6894

Rushmore, 1990, Regulation of glutathione s- transferase Ya subunit gene expression, Proc. Natl. Acad. Sci. USA, 87, 3826, 10.1073/pnas.87.10.3826

Rushmore, 1990, Transcriptional regulation of the rat glutathione s-transferase Ya subunit gene, J. Biol. Chem., 265, 14648, 10.1016/S0021-9258(18)77351-1

Rushmore, 1991, The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity, J. Biol. Chem., 266, 11632, 10.1016/S0021-9258(18)99004-6

Friling, 1990, Xenobiotic-inducible expression of murine glutathione s-transferase Ya subunit gene is controlled by an electrophile-responsive element, Proc. Natl. Acad. Sci. USA, 87, 6258, 10.1073/pnas.87.16.6258

Friling, 1992, Two adjacent AP-1–like binding sites form the electrophile responsive element of the murine glutathione S-transferase Ya subunit gene, Proc. Natl. Acad. Sci. USA, 89, 668, 10.1073/pnas.89.2.668

Okuda, 1990, Functional cooperativity between two TPA responsive elements in undifferentiated F9 embryonic stem cells, EMBO J, 9, 1131, 10.1002/j.1460-2075.1990.tb08219.x

Angel, 1991, The role of Jun, Fos and AP-1 complex in cell proliferation and transformation, Biochem. Biophys. Acta, 1072, 129

Prestera, 1993, Chemical and molecular regulation of enzymes that detoxify carcinogens, Proc. Natl. Acad. Sci. USA, 90, 2965, 10.1073/pnas.90.7.2965

Wasserman, 1997, Functional antioxidant responsive elements, Proc. Natl. Acad. Sci. USA, 94, 5361, 10.1073/pnas.94.10.5361

Bergelson, 1994, Induction of AP-1 (Fos/Jun) by chemical agents mediates activation of glutathione s-transferase and quinone reductase gene expression, Oncogene, 9, 565

Venugopal, 1996, Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element–mediated expression of NAD(P)H:quinone oxidoreductase 1 gene, Proc. Natl. Acad. Sci. USA, 93, 14960, 10.1073/pnas.93.25.14960

Liu, 1996, The rat liver glutathione s-transferase Ya subunit gene, Biochemistry, 35, 11517, 10.1021/bi960572p

Vasliou, 1995, Interaction between the Ah-receptor and proteins binding to the AP-1–like electrophile response element (EpRE) during murine phase II [Ah] battery gene expression, Biochem. Pharm., 12, 2057, 10.1016/0006-2952(95)02108-6

Yoshioka, 1995, Antitumor promotion by phenolic antioxidants, Proc. Natl. Acad. Sci. USA, 92, 4972, 10.1073/pnas.92.11.4972

Montano, 1998, Transcriptional regulation of the human quinone reductase gene by antiestrogen-liganded estrogen receptor α and estrogen receptor β, J. Biol. Chem., 273, 25443, 10.1074/jbc.273.39.25443

Venugopal, 1998, Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element–mediated expression and coordinated induction of genes encoding detoxifying enzymes, Oncogene, 17, 3145, 10.1038/sj.onc.1202237

Itoh, 1997, An Nrf2/small maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements, Biochem. Biophys. Res. Commun., 236, 313, 10.1006/bbrc.1997.6943

Itoh, 1999, Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain, Genes Dev, 13, 76, 10.1101/gad.13.1.76

Wilkinson, 1998, Disruption of c-Fos leads to increased expression of NAD(P)H:quinone oxidoreductase 1 and glutathione s-transferase, Biochem. Biophys. Res. Commun., 253, 855, 10.1006/bbrc.1998.9804

Marini, 1997, HMAF, a small human transcription factor that heterodimerizes specifically with Nrf1 and Nrf2, J. Biol. Chem., 272, 16490, 10.1074/jbc.272.26.16490

De Long, 1987, Role of cytochrome P1-450 in the induction of NAD(P)H:quinone reductase in a murine hepatoma cell line and its mutants, Carcinogenesis, 8, 1549, 10.1093/carcin/8.10.1549

Pinkus, 1996, Role of oxidants and antioxidants in the induction of AP-1, NF-κB, and glutathione s-transferase gene expression, J. Biol. Chem., 271, 13422, 10.1074/jbc.271.23.13422

Favreau, 1991, Transcriptional regulation of the rat NAD(P)H:quinone reductase gene. Identification of regulatory elements controlling basal level expression and inducible expression by planar aromatic compounds and phenolic antioxidants, J. Biol. Chem., 266, 4556, 10.1016/S0021-9258(20)64358-7

Li, 1994, Human antioxidant response element–mediated regulation of type 1 NAD(P)H:quinone oxidoreductase gene expression, Eur. J. Biochem., 226, 31, 10.1111/j.1432-1033.1994.tb20023.x

Demple, 1991, Redox redux, Cell, 67, 837, 10.1016/0092-8674(91)90355-3

Meyer, 1993, H2O2 and antioxidants have opposite effects on activation of NF-κB and AP-1 in intact cells, EMBO J, 12, 2005, 10.1002/j.1460-2075.1993.tb05850.x

Zheng, 1998, Activation of the OxyR transcription factor by reversible disulfide bond formation, Science, 279, 1718, 10.1126/science.279.5357.1718